EY728543

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: KCC2B_MOUSE (Calcium/calmodulin-dependent protein kinase type II subunit beta OS=Mus musculus GN=Camk2b PE=1 SV=2)

HSP 1 Score: 162.925 bits (411), Expect = 2.200e-39
Identity = 88/199 (44.22%), Postives = 129/199 (64.82%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTAVDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSVFFRPGEQ-FNEIVGSPYYMAPEVLKRN-YGPEVDVWSAGVILYILLCGVPPFWAETE 603
            G F V   C  +  G ++A K I+ KKL +A D + + RE +I + L KH NIV L D+  ++   ++V +L  GGELF+ IVAR +Y+E  A+  ++ I+E V  CH+ GV+HRDLKPEN L A+K + + +K  DFGL++  +  +Q +    G+P Y++PEVL++  YG  VD+W+ GVILYILL G PPFW E +
Sbjct:   23 GAFSVVRRCVKLCTGHEYAAKIINTKKL-SARDHQKLEREARICRLL-KHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQ 219          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: KCC2B_HUMAN (Calcium/calmodulin-dependent protein kinase type II subunit beta OS=Homo sapiens GN=CAMK2B PE=1 SV=2)

HSP 1 Score: 162.925 bits (411), Expect = 2.200e-39
Identity = 88/199 (44.22%), Postives = 129/199 (64.82%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTAVDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSVFFRPGEQ-FNEIVGSPYYMAPEVLKRN-YGPEVDVWSAGVILYILLCGVPPFWAETE 603
            G F V   C  +  G ++A K I+ KKL +A D + + RE +I + L KH NIV L D+  ++   ++V +L  GGELF+ IVAR +Y+E  A+  ++ I+E V  CH+ GV+HRDLKPEN L A+K + + +K  DFGL++  +  +Q +    G+P Y++PEVL++  YG  VD+W+ GVILYILL G PPFW E +
Sbjct:   23 GAFSVVRRCVKLCTGHEYAAKIINTKKL-SARDHQKLEREARICRLL-KHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQ 219          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: KCC2B_BOVIN (Calcium/calmodulin-dependent protein kinase type II subunit beta OS=Bos taurus GN=CAMK2B PE=2 SV=1)

HSP 1 Score: 162.925 bits (411), Expect = 2.200e-39
Identity = 88/199 (44.22%), Postives = 129/199 (64.82%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTAVDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSVFFRPGEQ-FNEIVGSPYYMAPEVLKRN-YGPEVDVWSAGVILYILLCGVPPFWAETE 603
            G F V   C  +  G ++A K I+ KKL +A D + + RE +I + L KH NIV L D+  ++   ++V +L  GGELF+ IVAR +Y+E  A+  ++ I+E V  CH+ GV+HRDLKPEN L A+K + + +K  DFGL++  +  +Q +    G+P Y++PEVL++  YG  VD+W+ GVILYILL G PPFW E +
Sbjct:   23 GAFSVVRRCVKLCTGHEYAAKIINTKKL-SARDHQKLEREARICRLL-KHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQ 219          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: DCLK3_MOUSE (Serine/threonine-protein kinase DCLK3 OS=Mus musculus GN=Dclk3 PE=2 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 5.294e-39
Identity = 80/195 (41.03%), Postives = 119/195 (61.03%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTAVDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLF-ANKKESSPLKAIDFGLSVF-FRPGEQFNEIVGSPYYMAPEVL-KRNYGPEVDVWSAGVILYILLCGVPPF 588
            G F     C      + +A K I K +L+   DI D   E+ I++ L  HPNIV L + YE ++ ++++ME  +GG+LFD IV    + E  AA ++  + + +   H++ ++HRD+KPEN L   N+ +S  LK  DFGL+ +  RP      + G+P Y+APE+L ++ YG EVD+W+AGVILYILLCG PPF
Sbjct:  352 GNFATVKECRHRETKQAYAMKMIDKSQLKGKEDIVD--SEILIIQSL-SHPNIVKLHEVYETEAEIYLIMEYVQGGDLFDAIVENVKFPEPEAAVMITDLCKALVHMHDKNIVHRDVKPENLLVQRNEDKSITLKLADFGLAKYVVRP---IFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPF 540          

HSP 2 Score: 40.0466 bits (92), Expect = 5.294e-39
Identity = 15/32 (46.88%), Postives = 23/32 (71.88%), Query Frame = 2

Query:  659 WPKVPENAKDLVKKMLNPDPKPKLTAEEILEH 754
            W  + + AKDLV+ +L  DPK + TAE++L+H
Sbjct:  566 WDNISDAAKDLVRNLLEVDPKKRYTAEQVLQH 597          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: DAPK3_HUMAN (Death-associated protein kinase 3 OS=Homo sapiens GN=DAPK3 PE=1 SV=1)

HSP 1 Score: 152.14 bits (383), Expect = 6.922e-39
Identity = 81/205 (39.51%), Postives = 123/205 (60.00%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKL---RTAVDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSP-LKAIDFGLSVFFRPGEQFNEIVGSPYYMAPEVLKRNYGP---EVDVWSAGVILYILLCGVPPFWAETEQ 606
            G+F +   C     G+++A K I K++L   R  V  E++ REV I++ + +HPNI++L D +E+ + V +++EL  GGELFD +  +   TE  A   +K I++ V   H + + H DLKPEN +  +K   +P +K IDFG++     G +F  I G+P ++APE++  NY P   E D+WS GVI YILL G  PF  ET+Q
Sbjct:   22 GQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREI-RHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIV--NYEPLGLEADMWSIGVITYILLSGASPFLGETKQ 223          

HSP 2 Score: 30.4166 bits (67), Expect = 6.922e-39
Identity = 15/44 (34.09%), Postives = 23/44 (52.27%), Query Frame = 2

Query:  674 ENAKDLVKKMLNPDPKPKLTAEEILEHLGYKCQKAQCSWVNGTR 805
            E AKD ++++L  DPK ++T  + LEH          SW+   R
Sbjct:  246 ELAKDFIRRLLVKDPKRRMTIAQSLEH----------SWIKAIR 279          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: MYLKA_DICDI (Myosin light chain kinase A OS=Dictyostelium discoideum GN=mlkA PE=1 SV=2)

HSP 1 Score: 155.992 bits (393), Expect = 1.182e-38
Identity = 83/197 (42.13%), Postives = 120/197 (60.91%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTAVDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSVFFRPGEQFNEIVGSPYYMAPEVLK-RNYGPEVDVWSAGVILYILLCGVPPFWAET 600
            G F + YL  +    +++A K I+K +L    + ++++ EV I+K +  HPNI++LK+ ++    +++VMEL  GGELFD+IV +G Y+E  AA ++K IV  V   H   ++HRDLKPEN L  +K+    +   DFGLS             G+P Y+APEVL    Y  EVD+WS GVI YILLCG PPF+ +T
Sbjct:   17 GAFSIVYLGENKQTKQRYAIKVINKSELGKDYE-KNLKMEVDILKKV-NHPNIIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQTLVMQTACGTPSYVAPEVLNATGYDKEVDMWSIGVITYILLCGFPPFYGDT 211          

HSP 2 Score: 25.7942 bits (55), Expect = 1.182e-38
Identity = 11/32 (34.38%), Postives = 16/32 (50.00%), Query Frame = 2

Query:  659 WPKVPENAKDLVKKMLNPDPKPKLTAEEILEH 754
            W  + + AKD + K+L  D   +L A   L H
Sbjct:  231 WGGISKEAKDFIGKLLVVDVSKRLNATNALNH 262          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: PHKG2_RAT (Phosphorylase b kinase gamma catalytic chain, testis/liver isoform OS=Rattus norvegicus GN=Phkg2 PE=2 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 1.533e-38
Identity = 76/205 (37.07%), Postives = 119/205 (58.05%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTAVD-IEDVR----REVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSVFFRPGEQFNEIVGSPYYMAPEVLK-------RNYGPEVDVWSAGVILYILLCGVPPFW 591
            G   V   C     G++FA K +     R +++ +E+VR    RE+ I++ +  HP+I++L D+YE  S + +V +L   GELFD +  +   +E+   ++M++++E V   H   ++HRDLKPEN L     ++  ++  DFG S    PGE+  E+ G+P Y+APE+LK         YG EVD+W+ GVIL+ LL G PPFW
Sbjct:   33 GVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVNFLHVNNIVHRDLKPENILL---DDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFW 234          

HSP 2 Score: 36.1946 bits (82), Expect = 1.533e-38
Identity = 16/44 (36.36%), Postives = 23/44 (52.27%), Query Frame = 2

Query:  659 WPKVPENAKDLVKKMLNPDPKPKLTAEEILEHLGYKCQKAQCSW 790
            W       KDL+ K+L  DP  +LTAE+ L+H  ++  K    W
Sbjct:  257 WDDRSNTVKDLIAKLLQVDPNARLTAEQALQHPFFERCKGSQPW 300          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: CDPK1_PLAFK (Calcium-dependent protein kinase 1 OS=Plasmodium falciparum (isolate K1 / Thailand) GN=CPK1 PE=1 SV=2)

HSP 1 Score: 159.844 bits (403), Expect = 1.862e-38
Identity = 83/210 (39.52%), Postives = 123/210 (58.57%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKK---KLRTAVDI---------EDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSVFFRPGEQFNEIVGSPYYMAPEVLKRNYGPEVDVWSAGVILYILLCGVPPFWAETEQ 606
            G +G   LC + +   + A K I K    K++ ++           E++  E+ ++K L  HPNI+ L D +ED    ++V E  EGGELF++I+ R  + E  AA +MK I+  +   H+  ++HRD+KPEN L  NK     +K +DFGLS FF    +  + +G+ YY+APEVL++ Y  + DVWS GVILYILLCG PPF  + +Q
Sbjct:   65 GAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNEISLLKSLD-HPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKLRDRLGTAYYIAPEVLRKKYNEKCDVWSCGVILYILLCGYPPFGGQNDQ 273          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: CDPK1_PLAF7 (Calcium-dependent protein kinase 1 OS=Plasmodium falciparum (isolate 3D7) GN=CPK1 PE=3 SV=2)

HSP 1 Score: 159.844 bits (403), Expect = 1.862e-38
Identity = 83/210 (39.52%), Postives = 123/210 (58.57%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKK---KLRTAVDI---------EDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSVFFRPGEQFNEIVGSPYYMAPEVLKRNYGPEVDVWSAGVILYILLCGVPPFWAETEQ 606
            G +G   LC + +   + A K I K    K++ ++           E++  E+ ++K L  HPNI+ L D +ED    ++V E  EGGELF++I+ R  + E  AA +MK I+  +   H+  ++HRD+KPEN L  NK     +K +DFGLS FF    +  + +G+ YY+APEVL++ Y  + DVWS GVILYILLCG PPF  + +Q
Sbjct:   65 GAYGEVLLCREKHGHGEKAIKVIKKSQFDKMKYSITNKIECDDKIHEEIYNEISLLKSLD-HPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICYLHKHNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDNKLRDRLGTAYYIAPEVLRKKYNEKCDVWSCGVILYILLCGYPPFGGQNDQ 273          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: CCAMK_LILLO (Calcium and calcium/calmodulin-dependent serine/threonine-protein kinase OS=Lilium longiflorum GN=CCAMK PE=1 SV=1)

HSP 1 Score: 147.132 bits (370), Expect = 2.594e-38
Identity = 76/165 (46.06%), Postives = 106/165 (64.24%), Query Frame = 1

Query:  136 QIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSVFFRPGEQFNEIVGSPYYMAPEVL-KRNYGPEVDVWSAGVILYILLCGVPPFWAETEQGGTQAII 627
            +I++ +  HPN++ L D YED + VH+V+ELC GGELFDRIVA+  Y+E  AA V++ I   +   H+  ++HRDLKPEN LF N+++ S LK +DFGLS      +    + GS  Y++PE L +R      D+WS GVILYILL G PPF A + +   Q I+
Sbjct:   93 RIVEDVSPHPNVIHLHDVYEDANGVHLVLELCSGGELFDRIVAQDRYSESEAAEVVQQIASGLAALHKSTIIHRDLKPENCLFLNQEKRSTLKIMDFGLSSVEDFTDPIVALFGSIDYVSPEALSQRQVSSASDMWSLGVILYILLSGCPPFHAPSNREKQQRIL 257          

HSP 2 Score: 33.4982 bits (75), Expect = 2.594e-38
Identity = 14/51 (27.45%), Postives = 27/51 (52.94%), Query Frame = 2

Query:  602 NKGVHRQLFAQWIDLRGTPWPKVPENAKDLVKKMLNPDPKPKLTAEEILEH 754
            N+   +++ A         W  +  +AKDL+  +L+ DP  + TA ++L+H
Sbjct:  249 NREKQQRILAGDFSFEEHTWKTITSSAKDLISSLLSVDPYKRPTANDLLKH 299