EY728245

BLAST of EY728245 vs. ExPASy Swiss-Prot
Match: VPS34_YEAST (Phosphatidylinositol 3-kinase VPS34 OS=Saccharomyces cerevisiae GN=VPS34 PE=1 SV=1)

HSP 1 Score: 141.739 bits (356), Expect = 5.515e-33
Identity = 85/235 (36.17%), Postives = 125/235 (53.19%), Query Frame = 2

Query:    8 SGLSQFLVQRXSHNIELASFLRWYVSVEFHDPVHAKRFYSTHEILEESMMKLTPGVDGEDGYKLWQSLVRQTELTAQLCSIMRDVGNVRGNTQKKIEKXXXXXXXXXXXXTYFEEPIRSPLAPNILITGIVPSESSIFKSALHPLRLTFRTASGGTCKMIFKKGDDIRQDQLVVQMVSLMDRLLKLENLDLHLTPYNVLATGQDEGLVEFIPSRSFTQILSELRXIISYLQRFHP 712
            S L++FL++R   N  L SF  WY+  E  D  +        +IL     +L      +    +    VR   +  + C  ++    ++  T KK+E                  PI  PL P++LI  + P  S +FKS+L PL++TF+T       ++FK GDD+RQDQLVVQ++SLM+ LLK EN+DL LTPY +LATG  EG +EFIP+ +   ILS+   I+ YL+  +P
Sbjct:  478 SPLAEFLIRRALVNPRLGSFFYWYLKSESEDKPYLD------QILSSFWSRLD-----KKSRNILNDQVRLINVLRECCETIK---RLKDTTAKKMELLVHLLETKVRPLVKVR-PIALPLDPDVLICDVCPETSKVFKSSLSPLKITFKTTLNQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLASILSKYHGILGYLKLHYP 697          

BLAST of EY728245 vs. ExPASy Swiss-Prot
Match: VPS34_CANAL (Phosphatidylinositol 3-kinase VPS34 OS=Candida albicans GN=VPS34 PE=3 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 5.707e-30
Identity = 84/245 (34.29%), Postives = 125/245 (51.02%), Query Frame = 2

Query:    8 SGLSQFLVQRXSHNIELASFLRWYVSVEFHDPVHAKRFYSTHEILEESM---MKLTPGVDGEDGYKLWQSLVRQTELTAQLCSI---MRDVGNVRGNTQKKIEKXXXXXXXXXXXXTYFEEPIRSPLAPNILITGIVPSESSIFKSALHPLRLTFRTASG-----------------GTCKMIFKKGDDIRQDQLVVQMVSLMDRLLKLENLDLHLTPYNVLATGQDEGLVEFIPSRSFTQILSE 673
            S L+ FL++R   N +L +F  WYV VE  D ++        +I  + +   ++L      E+    ++ L  Q     +L S+   +R        T KK+E               F EP   PL P+++I G  P ESS+FKS+L PL++T +T                    G   ++FK GDD+RQDQLV+Q++ LMD+LLK ENLDL LTPY +LAT    GL++F+P+ +   ILS+
Sbjct:  530 SPLADFLIERAVENEKLGNFFYWYVKVENEDQLNNPHIDGPIKIYMDILNRYIELLKAHCHENRLPYYKHLKHQIWFIKKLTSLVELLRASFKKNEATAKKVEYLREYLANSGNELLKFPEPFPLPLDPSVMICGCYPEESSVFKSSLAPLKITLKTIEKKKHGHATSQLFGKRSRYGKYPLMFKIGDDLRQDQLVIQIIDLMDQLLKNENLDLKLTPYKILATSPISGLIQFVPNETLDSILSK 774          

BLAST of EY728245 vs. ExPASy Swiss-Prot
Match: P3C2A_HUMAN (Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens GN=PIK3C2A PE=1 SV=2)

HSP 1 Score: 91.6633 bits (226), Expect = 6.545e-18
Identity = 61/216 (28.24%), Postives = 111/216 (51.39%), Query Frame = 2

Query:    8 SGLSQFLVQRXSHNIELASFLRWYVSVEFHDPVHAKRFYSTHEILEESMMKLTPGVDGEDGYKLWQSLVRQTELTAQLCSIMRDVGNVRGNTQKKIEKXXXXXXXXXXXXTYFEE-PIRSPLAPNILITGIVPSESSIFKSALHPLRLTFRTAS--GGTCKMIFKKGDDIRQDQLVVQMVSLMDRLLKLENLDLHLTPYNVLATGQDEGLVEFIPS 646
            S L QFL+ R   NI++A  L W +     D +H  +F + +E +  +++ +        G +L + L++QT+L   L  +   V    G+ ++ + +            ++F++   R PL P+++   +     S F S   PL++T   A   G    ++FK G+D+RQD L +QM+ +MD++   E LDL +  +  L+TG+D G+VE +P+
Sbjct:  990 SSLVQFLLSRALGNIQIAHNLYWLLK----DALHDVQFSTRYEHVLGALLSV-------GGKRLREELLKQTKLVQLLGGVAEKVRQASGSARQVVLQRSMERVQ-----SFFQKNKCRLPLKPSLVAKELNIKSCSFFSSNAVPLKVTMVNADPMGEEINVMFKVGEDLRQDMLALQMIKIMDKIWLKEGLDLRMVIFKCLSTGRDRGMVELVPA 1189          

BLAST of EY728245 vs. ExPASy Swiss-Prot
Match: PK3CD_HUMAN (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform OS=Homo sapiens GN=PIK3CD PE=1 SV=2)

HSP 1 Score: 91.2781 bits (225), Expect = 8.548e-18
Identity = 67/212 (31.60%), Postives = 100/212 (47.17%), Query Frame = 2

Query:   14 LSQFLVQRXSHNIELASFLRWYVSVEFHDPVHAKRFYSTHEILEESMMKLTPGVDGEDGYKLWQSLVRQTELTAQLCSIMRDVGNVRGNTQKKIEKXXXXXXXXXXXXTYFEEPIRSPLAPNILITGIVPSESSIFKSALHPLRLTF---RTASGGTCKMIFKKGDDIRQDQLVVQMVSLMDRLLKLENLDLHLTPYNVLATGQDEGLVEFI 640
            L++FL+ R   N ++  FL W++  E H P  A RF     ILE      T  +         + L++Q E  ++L ++   V      T K   K                  ++SPL P+ L+  +   + +   S + PL + +      SGG+  +IFK GDD+RQD L +QM+ LMD L K E LDL +TPY  L TG   GL+E +
Sbjct:  629 LTKFLLDRALANRKIGHFLFWHLRSEMHVPSVALRFGL---ILEAYCRGSTHHM---------KVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMRQEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVV 828          

BLAST of EY728245 vs. ExPASy Swiss-Prot
Match: P3C2A_PONAB (Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Pongo abelii GN=PIK3C2A PE=2 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 1.458e-17
Identity = 61/216 (28.24%), Postives = 110/216 (50.93%), Query Frame = 2

Query:    8 SGLSQFLVQRXSHNIELASFLRWYVSVEFHDPVHAKRFYSTHEILEESMMKLTPGVDGEDGYKLWQSLVRQTELTAQLCSIMRDVGNVRGNTQKKIEKXXXXXXXXXXXXTYFEE-PIRSPLAPNILITGIVPSESSIFKSALHPLRLTFRTAS--GGTCKMIFKKGDDIRQDQLVVQMVSLMDRLLKLENLDLHLTPYNVLATGQDEGLVEFIPS 646
            S L QFL+ R   NI++A  L W +     D +H  +F + +E +  +++ +        G +L + L +QT+L   L  +   V    G+ ++ + +            ++F++   R PL P+++   +     S F S   PL++T   A   G    ++FK G+D+RQD L +QM+ +MD++   E LDL +  +  L+TG+D G+VE +P+
Sbjct:  988 SSLVQFLLSRALGNIQIAHNLYWLLK----DALHDVQFSTRYEHVLGALLSV-------GGKRLREELRKQTKLVQLLGGVAEKVRQASGSARQVVLQRSMERVQ-----SFFQKNKCRLPLKPSLVAKELSIKSCSFFSSNAVPLKVTMVNADPMGEEINVMFKVGEDLRQDMLALQMIKIMDKIWLKEGLDLRMVIFKCLSTGRDRGMVELVPA 1187          

BLAST of EY728245 vs. ExPASy Swiss-Prot
Match: P3C2A_MOUSE (Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Mus musculus GN=Pik3c2a PE=1 SV=2)

HSP 1 Score: 89.3521 bits (220), Expect = 3.248e-17
Identity = 63/220 (28.64%), Postives = 105/220 (47.73%), Query Frame = 2

Query:    8 SGLSQFLVQRXSHNIELASFLRWYVSVEFHDPVHAKRFYSTHEILEESMMKLTPGVDGEDGYKLWQSLVRQTELTAQLCSIMRDVGNVRGNT-----QKKIEKXXXXXXXXXXXXTYFEEPIRSPLAPNILITGIVPSESSIFKSALHPLRLTFRTAS--GGTCKMIFKKGDDIRQDQLVVQMVSLMDRLLKLENLDLHLTPYNVLATGQDEGLVEFIPS 646
            S L +FL+ R   NI++A  L W +     D +H   F S +E +  +++ +        G  L + L +Q +L   L  +   V    G+T     QK +E+             +     R PL P+++   +     S F S   PL++T   A   G    ++FK G+D+RQD L +QM+ +MD++   E LDL +  +  L+TG+D G+VE +P+
Sbjct:  990 SSLVRFLLSRALGNIQIAHSLYWLLK----DALHDTHFGSRYEHVLGALLSV-------GGKGLREELSKQMKLVQLLGGVAEKVRQASGSTRQVVLQKSMERVQSF---------FLRNKCRLPLKPSLVAKELNIKSCSFFSSNAMPLKVTMVNADPLGEEINVMFKVGEDLRQDMLALQMIKIMDKIWLKEGLDLRMVIFRCLSTGRDRGMVELVPA 1189          

BLAST of EY728245 vs. ExPASy Swiss-Prot
Match: PK3CD_MOUSE (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform OS=Mus musculus GN=Pik3cd PE=1 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 1.612e-16
Identity = 68/214 (31.78%), Postives = 102/214 (47.66%), Query Frame = 2

Query:   14 LSQFLVQRXSHNIELASFLRWYVSVEFHDPVHAKRFYSTHEILEESMMKLTPGVDGEDGYKLWQSLVRQTELTAQLCSIMRDVGNVRGNTQKKIEKXXXXXXXXXXXXTYFE--EPIRSPLAPNILITGIVPSESSIFKSALHPLRLTFRT---ASGGTCKMIFKKGDDIRQDQLVVQMVSLMDRLLKLENLDLHLTPYNVLATGQDEGLVEFI 640
            L++FL+ R   N ++  FL W++  E H P  A RF     I+E      T  +         + L++Q E  ++L ++   V      T K   K            TY E    ++SPL P+ L+  +   + +   S + PL + + +    S G   +IFK GDD+RQD L +QM+ LMD L K E LDL +TPY  L TG   GL+E +
Sbjct:  628 LTKFLLGRALANRKIGHFLFWHLHSEMHVPSVALRFGL---IMEAYCRGSTHHM---------KVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQE--TYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVV 827          

BLAST of EY728245 vs. ExPASy Swiss-Prot
Match: P3C2B_HUMAN (Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta OS=Homo sapiens GN=PIK3C2B PE=1 SV=2)

HSP 1 Score: 85.5001 bits (210), Expect = 4.691e-16
Identity = 45/130 (34.62%), Postives = 75/130 (57.69%), Query Frame = 2

Query:  359 RSPLAPNILITGIVPSESSIFKSALHPLRLTFRTAS--GGTCKMIFKKGDDIRQDQLVVQMVSLMDRLLKLENLDLHLTPYNVLATGQDEGLVEFIPSRSFTQILS---------ELRXIISYLQRFHPG 715
            R PL+P++L+ GIVP + S F S   PL+L+F+     G   ++IFK GDD+RQD L +QM+ +M ++   E LD+ +  +   +TG+  G+VE IP+    + +          + R +  +LQ+ +PG
Sbjct: 1037 RLPLSPSLLVKGIVPRDCSYFNSNAVPLKLSFQNVDPLGENIRVIFKCGDDLRQDMLTLQMIRIMSKIWVQEGLDMRMVIFRCFSTGRGRGMVEMIPNAETLRKIQVEHGVTGSFKDRPLADWLQKHNPG 1166          

BLAST of EY728245 vs. ExPASy Swiss-Prot
Match: PI3K3_DICDI (Phosphatidylinositol 3-kinase 3 OS=Dictyostelium discoideum GN=pikC PE=2 SV=2)

HSP 1 Score: 83.9593 bits (206), Expect = 1.365e-15
Identity = 63/218 (28.90%), Postives = 100/218 (45.87%), Query Frame = 2

Query:    2 HASGLSQFLVQRXSHNIELASF-LRWYVSVEFHDPVHAKRFYSTHEILEESMMKLTPGVDGEDGYKLWQSLVRQTELTAQLCSIMRDVGNVRGNTQKKIEKXXXXXXXXXXXXTYFEEPIRSPLAPNILITGIVPSESSIFKSALHPLRLTFRTAS--GGTCKMIFKKGDDIRQDQLVVQMVSLMDRLLKLENLDLHLTPYNVLATGQDEGLVEFIPS 646
            H S LS FL+ R   N+++      W++  +  +    +RF     +L    ++  P        +L +S  R+      L ++ + V  V        EK              F   +  P  P+I I  I+P +     SA  PL +TF+ A       +MI K GDD+RQD L +Q++ LMD + K ++LDLH+T Y  +ATG   GL+E +P+
Sbjct: 1188 HNSVLSLFLIGRVWQNMQVLGHPFFWHLRADIDNQEVCERF----RVLSSGFLRYAPT-------QLMESFKREITTLRILENLAKRVKEV------PYEKRKQYVENNLREEQSFPTELFVPFDPSIRILNIIPEKCKSMDSAKVPLWVTFKNADPFAPPLQMIAKTGDDLRQDILTLQLLRLMDHMWKSQDLDLHMTIYRCIATGMGTGLIEVVPN 1388          

BLAST of EY728245 vs. ExPASy Swiss-Prot
Match: PK3CB_MOUSE (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform OS=Mus musculus GN=Pik3cb PE=2 SV=1)

HSP 1 Score: 81.2629 bits (199), Expect = 8.846e-15
Identity = 64/217 (29.49%), Postives = 100/217 (46.08%), Query Frame = 2

Query:   14 LSQFLVQRXSHNIELASFLRWYVSVEFHDPVHAKRFYSTHEILEES----MMKLTPGVDGEDGYKLWQSLVRQTELTAQLCSIMRDVGNVRGNTQKKIEKXXXXXXXXXXXXTYFE--EPIRSPLAPNILITGIVPSESSIFKSALHPLRLTFRTASGG--TCKMIFKKGDDIRQDQLVVQMVSLMDRLLKLENLDLHLTPYNVLATGQDEGLVEFI 640
            LS+FL++R   N  +  FL W++  E H P  + +F    E         M  L+  V+  +  K   SL++   +      + R  G    +T  K                Y E    ++SPL P ++++ +   +     S + PL L + + + G  +  +IFK GDD+RQD L +QM+ LMD L K   LDL + PY  LATG   GL+E +
Sbjct:  650 LSRFLLERALDNRRIGQFLFWHLRSEVHTPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAV-----KLSRAKGKEAMHTCLK-------------QSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYSSRAFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVV 848