EY728231

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: ABL_DROME (Tyrosine-protein kinase Abl OS=Drosophila melanogaster GN=Abl PE=1 SV=3)

HSP 1 Score: 75.8702 bits (185), Expect = 3.036e-13
Identity = 48/147 (32.65%), Postives = 81/147 (55.10%), Query Frame = 1

Query:  292 NKLGEGGFGTVYKGVIGQ-GEIAVKRLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIV 729
            +KLG G +G VY+ V  + G     + L +    +K+   EA+++ +++H NLV+L+G C  +    +I E+M + +L  FL     RE LD    + +   +A G+ YL   +    IHRDL A N L+  +   K++DFG+AR++
Sbjct:  375 HKLGGGQYGEVYEAVWKRYGNTVAVKTLKEDTMALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFL-RSAGRETLDAVALLYMATQIASGMSYLESRN---YIHRDLAARNCLVGDNKLVKVADFGLARLM 517          

HSP 2 Score: 20.4014 bits (41), Expect = 3.036e-13
Identity = 8/13 (61.54%), Postives = 11/13 (84.62%), Query Frame = 2

Query:  821 EFFDKSDVFSFGV 859
            +F  KSDV++FGV
Sbjct:  544 KFSTKSDVWAFGV 556          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: MATK_HUMAN (Megakaryocyte-associated tyrosine-protein kinase OS=Homo sapiens GN=MATK PE=1 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 3.124e-13
Identity = 50/154 (32.47%), Postives = 86/154 (55.84%), Query Frame = 1

Query:  295 KLGEGGFGTVYKGVIGQGEIAVKRLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDEL 756
            ++GEG FG V +G     ++AVK +  K     +   +E +V+ ++QH+NLV+LLG  + +    ++ E++   +L  FL     R +++    +Q    VA+G+ YL      +++HRDL A NIL+ +D+  K+SDFG+A+    G D   L
Sbjct:  240 QIGEGEFGAVLQGEYLGQKVAVKNI--KCDVTAQAFLDETAVMTKMQHENLVRLLGVILHQG-LYIVMEHVSKGNLVNFL-RTRGRALVNTAQLLQFSLHVAEGMEYLESK---KLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRL 386          

HSP 2 Score: 21.9422 bits (45), Expect = 3.124e-13
Identity = 9/13 (69.23%), Postives = 11/13 (84.62%), Query Frame = 2

Query:  821 EFFDKSDVFSFGV 859
            +F  KSDV+SFGV
Sbjct:  400 KFTSKSDVWSFGV 412          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: Y9853_DICDI (Probable serine/threonine-protein kinase DDB_G0271538 OS=Dictyostelium discoideum GN=DDB_G0271538 PE=3 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 3.615e-13
Identity = 55/178 (30.90%), Postives = 86/178 (48.31%), Query Frame = 1

Query:  295 KLGEGGFGTVYKGVIGQGEIAVKRL---LGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKD----MNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPE 807
            ++G G FG V K      ++AVK+L   +       K +  E  ++  ++H N+V+ +G C  +   +++ EY+    L  F+       I  W  R+++   +A    YLH     ++I RDLKA NIL+D+        K+ DFG ARI F G D + L      I G+   MSPE
Sbjct:   38 EIGRGSFGQVQKASYFGTDVAVKQLSTLVSIDPDYFKFMLREIKILKGMRHPNIVQYIGACCHEGRYMIVTEYIKGGDLHQFIKARGVSNI-SWTLRMKLALDIASAFSYLHS---KKVIFRDLKAKNILVDEIGDGLYRAKVIDFGFARI-FDGKDTNNL-----TICGSENTMSPE 205          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: EPHB3_DANRE (Ephrin type-B receptor 3 (Fragment) OS=Danio rerio GN=ephb3 PE=2 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 3.615e-13
Identity = 53/172 (30.81%), Postives = 91/172 (52.91%), Query Frame = 1

Query:  298 LGEGGFGTVYKGVIGQG-----EIAVKRL-LGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQ----IIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISG 783
            +G G FG V +G + Q       +A+K L  G +  + ++  +EAS++ Q  H N++ L G        L++ E+M N +LD FL       + D R  V     +++G+A G+ YL   S +  +HRDL A N+L++ ++  K+SDFG++R +   +D      +TS + G
Sbjct:  193 IGAGEFGEVCRGRLKQAGRKETTVAIKTLKAGYTEHQRRDFLSEASIMGQFDHPNVIHLEGVLTRSCPVLIVTEFMENGALDSFL------RLNDGRFTVTQLVGMLRGIAAGMKYL---SDMNYVHRDLAARNVLVNSNLVCKVSDFGLSRFL---DDNSSDPTYTSSLGG 352          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: ABL_FSVHY (Tyrosine-protein kinase transforming protein Abl OS=Feline sarcoma virus (strain Hardy-Zuckerman 2) GN=ABL PE=2 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 3.615e-13
Identity = 46/149 (30.87%), Postives = 83/149 (55.70%), Query Frame = 1

Query:  292 NKLGEGGFGTVYKGVIGQGEIAVK-RLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFG 735
            +KLG G +G VY+GV  +  + V  + L +   E++E   EA+V+ +++H NLV+LLG C  +    +I E+M   +L  +L +  ++E+      V ++    Q    +    +   IHRDL A N L+ ++   K++DFG++R++ G
Sbjct:  195 HKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV----NAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 339          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: ABL1_HUMAN (Proto-oncogene tyrosine-protein kinase ABL1 OS=Homo sapiens GN=ABL1 PE=1 SV=4)

HSP 1 Score: 75.8702 bits (185), Expect = 3.615e-13
Identity = 46/149 (30.87%), Postives = 83/149 (55.70%), Query Frame = 1

Query:  292 NKLGEGGFGTVYKGVIGQGEIAVK-RLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFG 735
            +KLG G +G VY+GV  +  + V  + L +   E++E   EA+V+ +++H NLV+LLG C  +    +I E+M   +L  +L +  ++E+      V ++    Q    +    +   IHRDL A N L+ ++   K++DFG++R++ G
Sbjct:  246 HKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV----NAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTG 390          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: SPKA_DICDI (Stress-activated protein kinase alpha OS=Dictyostelium discoideum GN=spkA-1 PE=1 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 4.722e-13
Identity = 53/180 (29.44%), Postives = 85/180 (47.22%), Query Frame = 1

Query:  295 KLGEGGFGTVYKGVIGQGEIAVKRLLGKS-GQEIKELKNEASVIAQVQHKNLVKLLGCCIEKD--------ERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPE 807
            KLG G  G VYKG+    E+A+K L   +  +EI+E K E  +++ ++ K++V   G  +E           R  +Y  M N SLD           + W    +      +G+  LH++    I+HRDLK+ N+L++     K+ DFG++R   G N           + GT+ Y +PE
Sbjct:  356 KLGAGSSGKVYKGLYRGKEVAIKVLKSMTESKEIEEFKKEFQIMSAIRSKHVVHFYGAVLEPKLCMVMENCSRGSLYHVMDNNSLD-----------IGWERTFRFAIETVRGIECLHKWDPP-IVHRDLKSLNLLVNDKWEIKVCDFGLSRFNTGSN-----LETLVKMRGTFAYCAPE 518          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: RYK_AVIR3 (Tyrosine-protein kinase transforming protein RYK OS=Avian retrovirus RPL30 GN=V-RYK PE=2 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 4.722e-13
Identity = 62/204 (30.39%), Postives = 99/204 (48.53%), Query Frame = 1

Query:  175 VELTEGNNKCKKGCEKEVDQFPLFSFSSVSSATGNFSAANKLGEGGFGTVYKGVIGQGE-----IAVK--RLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDER-----LLIYEYMPNKSLDCFLFDPTKR---EILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGN 741
            VELT G+     G   E+ Q        V       S    LGEG FG+V +G + Q E     +AVK  +L   S +EI+E  +EA+ I    H N++KLLG CIE   +     +++  +M    L  FL         + +  +  ++ +  +A G+ YL   S  + +HRDL A N +L  DM   ++DFG+++ ++ G+
Sbjct:   18 VELTLGS----LGVSSELQQ----KLQDVVIDRNALSLGKVLGEGEFGSVMEGRLSQPEGTPQKVAVKTMKLDNFSHREIEEFLSEAACIKDFDHPNVIKLLGVCIELSSQQIPKPMVVLPFMKYGDLHSFLLRSRLEMAPQFVPLQMLLKFMVDIALGMEYL---SSRQFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGD 210          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: ROS_MOUSE (Proto-oncogene tyrosine-protein kinase ROS OS=Mus musculus GN=Ros1 PE=2 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 4.722e-13
Identity = 68/225 (30.22%), Postives = 106/225 (47.11%), Query Frame = 1

Query:  217 EKEVDQFPLFSFSSVSSATGNFSAANKLGEGGFGTVYKGV------IGQGEI--AVKRLL-GKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFL-------FDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLD-KDMNP----KISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPEYALEGIF 828
            ++E++  P F    +S           LG G FG VY+G       +G GEI  AVK L  G + QE  E   EA ++++  H N++K LG C+  + + +I E M    L  +L       F      +LD    V++   +++G +YL Q   +  IHRDL A N L+  KD       KI DFG+AR ++  +   +       +     +M+PE  ++GIF
Sbjct: 1924 QEEIENLPAFPREKLSLRL-------LLGSGAFGEVYEGTAIDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLGEPQYIILELMEGGDLLSYLRKARGTTFHGPSLTLLD---LVELCVDISKGCVYLEQ---MHFIHRDLAARNCLVSVKDYTSPRVVKIGDFGLAREIYKNDYYRKRGEGLLPVR----WMAPENLMDGIF 2131          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: RIPK2_HUMAN (Receptor-interacting serine/threonine-protein kinase 2 OS=Homo sapiens GN=RIPK2 PE=1 SV=2)

HSP 1 Score: 75.485 bits (184), Expect = 4.722e-13
Identity = 48/147 (32.65%), Postives = 80/147 (54.42%), Query Frame = 1

Query:  298 LGEGGFGTVYKG--VIGQGEIAVKRLLGKS---GQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMAR 723
            L  G  GTV        + ++AVK L   +     E K++  EA ++ + +   ++ +LG C E +   ++ EYMPN SL+  L   T+   + W  R +I+  +A G+ YLH  +   ++H DLK  NILLD + + KI+DFG+++
Sbjct:   24 LSRGASGTVSSARHADWRVQVAVKHLHIHTPLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMT-PPLLHHDLKTQNILLDNEFHVKIADFGLSK 169