EY728231

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: NEK11_HUMAN (Serine/threonine-protein kinase Nek11 OS=Homo sapiens GN=NEK11 PE=1 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 8.054e-13
Identity = 59/194 (30.41%), Postives = 94/194 (48.45%), Query Frame = 1

Query:  295 KLGEGGFGTVYKGVIGQGEIAVKRLLGKSGQEIKELKN----------------EASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTK-------REILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPE 807
            KLG G FGTVY          V     K G+E+K LK                 EA +++++ H  +VK     +E+D   +I EY   + LD  + +  +        +I++W   +Q++ GV     Y+H+    RI+HRDLK+ N+ L  ++  KI DFG++R++ G  D        + ++GT  YMSPE
Sbjct:   34 KLGSGSFGTVY---------LVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWF--IQLLLGVD----YMHER---RILHRDLKSKNVFLKNNL-LKIGDFGVSRLLMGSCDL------ATTLTGTPHYMSPE 202          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: MERTK_RAT (Proto-oncogene tyrosine-protein kinase Mer OS=Rattus norvegicus GN=Mertk PE=2 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 8.054e-13
Identity = 52/163 (31.90%), Postives = 88/163 (53.99%), Query Frame = 1

Query:  298 LGEGGFGTVYKGVIGQGE-----IAVK--RLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDER-----LLIYEYMPNKSLDCFLFDPTKREI---LDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGN 741
            LGEG FG+V +G + Q +     +AVK  +L   S +EI+E  +EA+ +    H N+++LLG CIE   +     ++I  +M    L  FL       +   +  +T ++ +  +AQG+ YL   S    +HRDL A N +L  DM   ++DFG+++ ++ G+
Sbjct:  588 LGEGEFGSVMEGNLKQEDGTSQKVAVKTMKLDNFSLREIEEFLSEAACMKDFNHPNVIRLLGVCIELSSQGIPKPMVILPFMKYGDLHTFLLYSRIESVPKSIPLQTLLKFMVDIAQGMEYL---SSRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGD 747          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: M3K11_HUMAN (Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 8.054e-13
Identity = 59/185 (31.89%), Postives = 90/185 (48.65%), Query Frame = 1

Query:  298 LGEGGFGTVYKGVIGQGEIAVKRLLGKSGQEI----KELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPT--KREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILL-----DKDMNP---KISDFGMARIVFGGNDXDELXXHTS-XISGTYGYMSPE 807
            +G GGFG VY+G      +AVK       ++I    + ++ EA + A + H N++ L   C+E+    L+ EY     L   L         +++W  ++      A+G+ YLH  + V +IHRDLK++NILL       DM     KI+DFG+AR         E    T    +GTY +M+PE
Sbjct:  123 IGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQI------ARGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLAR---------EWHKTTQMSAAGTYAWMAPE 292          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: KXCA_DICDI (Kinase and exchange factor for Rac A OS=Dictyostelium discoideum GN=kxcA PE=3 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 8.054e-13
Identity = 49/145 (33.79%), Postives = 75/145 (51.72%), Query Frame = 1

Query:  298 LGEGGFGTVYKGVIGQGEIAVKRLLGKSGQEI-KELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNP-KISDFGMARI 726
            +G+G FG VY+G     E+A+K++      +  K  + E   +  ++H  +V   G C  +    LI E++    L  +L    K     W +RV I  GVA+  L+LH  +   ++HRDLK+ NILLD   N  K+ DFG AR+
Sbjct:   24 IGKGNFGCVYRGNYLGVEVAIKQIPSFDDPDYCKYTEREVKALRYIRHPFVVHFFGACKHESGFYLITEFIEGLDLRRYLKSVPKPP--KWLSRVNIALGVAKTFLFLHSKN---LLHRDLKSKNILLDISRNQIKLCDFGFARV 163          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: IRAK2_PONAB (Interleukin-1 receptor-associated kinase-like 2 OS=Pongo abelii GN=IRAK2 PE=2 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 8.054e-13
Identity = 48/158 (30.38%), Postives = 78/158 (49.37%), Query Frame = 1

Query:  244 FSFSSVSSATGNFSAANKLGEGGFGTVYKGVIGQGEIAVKRL----LGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKIS 705
            +S + V  AT +F+  +K+ +G F  VY+G         K+L        G   +  + E  +  +  H N++ +LG C  +     IY YM N SL   L      + L W  RV I  G+   + YLH    + IIH ++K+SN+LLD+++ PK++
Sbjct:  198 WSEADVVQATDDFNQNHKISQGTFADVYRGYRHGTPFVFKKLRETACSSPGSIERFFQAELQICLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRLQGQGGSDPLPWPQRVSICSGLLCAVEYLH---GLEIIHSNVKSSNVLLDQNLTPKLA 352          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: GDT4_DICDI (Probable serine/threonine-protein kinase gdt4 OS=Dictyostelium discoideum GN=gdt4 PE=3 SV=2)

HSP 1 Score: 74.7146 bits (182), Expect = 8.054e-13
Identity = 55/181 (30.39%), Postives = 90/181 (49.72%), Query Frame = 1

Query:  298 LGEGGFGTVYKGVIGQGEIAVKRLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILL-----DKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPEYALEGI 825
            L EG FG VY  +     +AVK  L K      E+  E S++++++H N+V  +G     +   ++ +Y P  SL+ +  +   +  L     ++I   +++   +LH+     IIHRDLK  N+L+     D  +  KISDFG  R + G ++ +         +GT  YMSPE  LEG+
Sbjct: 1355 LSEGSFGVVYSAIWRSSSVAVK--LFKHHYSKDEIDKETSILSKIKHPNIVSFIGSLNFLNTYGIVIDYHPRGSLNYYTRNQNIK--LSMVQNIRISLDISRACSFLHKNG---IIHRDLKPDNVLIVSFDPDSSICAKISDFGTCREINGKHELNSK-------AGTTRYMSPE-ILEGL 1520          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: ERBB_AVIER (Tyrosine-protein kinase transforming protein erbB OS=Avian erythroblastosis virus (strain ES4) GN=V-ERBB PE=3 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 8.054e-13
Identity = 60/194 (30.93%), Postives = 100/194 (51.55%), Query Frame = 1

Query:  280 FSAANKLGEGGFGTVYKGV-IGQGE-----IAVKRLL-GKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPT----KREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPEYALEGIF 828
            F     LG G FGT+YKG+ I +GE     +A+K L    S +  KE+ +EA V+A V + ++ +LLG C+    +L I + MP   L  ++ +       + +L+W  ++      A+G+ YL +    R++HRDL A N+L+    + KI+DFG+A+++      DE   H         +M+ E  L  I+
Sbjct:  132 FKKVKVLGSGAFGTIYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQL-ITQLMPYGCLLDYIREHKDNIGSQYLLNWCVQI------AKGMNYLEER---RLVHRDLAARNVLVKTPQHVKITDFGLAKLL----GADEKEYHAEGGKVPIKWMALESILHRIY 311          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: ERBB2_MOUSE (Receptor tyrosine-protein kinase erbB-2 OS=Mus musculus GN=Erbb2 PE=1 SV=3)

HSP 1 Score: 74.7146 bits (182), Expect = 8.054e-13
Identity = 64/189 (33.86%), Postives = 98/189 (51.85%), Query Frame = 1

Query:  298 LGEGGFGTVYKGV-IGQGE-----IAVKRLLGKSGQEI-KELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKR----EILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPEYALEGIFR 831
            LG G FGTVYKG+ I  GE     +A+K L   +  +  KE+ +EA V+A V    + +LLG C+    +L + + MP   L   + +   R    ++L+W  ++      A+G+ YL +   VR++HRDL A N+L+    + KI+DFG+AR++    D DE   H         +M    ALE I R
Sbjct:  727 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQL-VTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQI------AKGMSYLEE---VRLVHRDLAARNVLVKSPNHVKITDFGLARLL----DIDETEYHADGGKVPIKWM----ALESILR 897          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: EPHB2_COTJA (Ephrin type-B receptor 2 OS=Coturnix coturnix japonica GN=EPHB2 PE=2 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 8.054e-13
Identity = 66/219 (30.14%), Postives = 105/219 (47.95%), Query Frame = 1

Query:  154 GMNLKVDVELTEGNNKCKKGCEKEVDQFPLFSFSSVSSATGNFSAANKLGEGGFGTVYKGVI---GQGEIAVKRLLGKSGQEIKELKN---EASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQII---KGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISG 783
            GM + +D    E  N+  +   KE+D       S V            +G G FG V  G +   G+ EI V     KSG   K+ ++   EAS++ Q  H N++ L G   +    ++I E+M N SLD FL     R+     T +Q++   +G+A G+ YL   + +  +HRDL A N L++ ++  K+SDFG++R +    D      +TS + G
Sbjct:  593 GMKIYIDPFTYEDPNEAVREFAKEID------ISCVK-------IEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDSFL-----RQNDGQFTVIQLVGMLRGIAAGMKYL---ADMNYVHRDLAARNTLVNSNLVCKVSDFGLSRFL---EDDTSDPTYTSALGG 787          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: TYK2_HUMAN (Non-receptor tyrosine-protein kinase TYK2 OS=Homo sapiens GN=TYK2 PE=1 SV=3)

HSP 1 Score: 74.3294 bits (181), Expect = 8.697e-13
Identity = 54/158 (34.18%), Postives = 81/158 (51.27%), Query Frame = 1

Query:  298 LGEGGFGTVYKGVI-----GQGE-IAVKRLLGKSGQEIKE-LKNEASVIAQVQHKNLVKLLGCCIEKDERLL--IYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGND 744
            LGEG FG V          G GE +AVK L    G + +   K E  ++  + H++++K  GCC ++ E+ L  + EY+P  SL  +L     R  +     +   + + +G+ YLH       IHRDL A N+LLD D   KI DFG+A+ V  G++
Sbjct:  903 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSGWKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYL----PRHSIGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1053          

HSP 2 Score: 20.4014 bits (41), Expect = 8.697e-13
Identity = 8/13 (61.54%), Postives = 11/13 (84.62%), Query Frame = 2

Query:  821 EFFDKSDVFSFGV 859
            +F+  SDV+SFGV
Sbjct: 1077 KFYYASDVWSFGV 1089