EY728231

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: DLK1_CAEEL (Mitogen-activated protein kinase kinase kinase dlk-1 OS=Caenorhabditis elegans GN=dlk-1 PE=1 SV=4)

HSP 1 Score: 74.3294 bits (181), Expect = 1.052e-12
Identity = 50/170 (29.41%), Postives = 83/170 (48.82%), Query Frame = 1

Query:  298 LGEGGFGTVYKGVIGQGEIAVKRLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPE 807
            LG G  G V++G +    +AVK++      EIK L++       ++H+N+++ LG C +     ++ EY     L   L     R  +      Q +K +A G+ YLHQ    ++IHRDLK+ NIL+  + + KI DFG + +        ++        GT  +M+PE
Sbjct:  141 LGSGSQGAVFRGQLENRTVAVKKVNQLKETEIKHLRH-------LRHQNIIEFLGVCSKSPCYCIVMEYCSKGQLCTVL---KSRNTITRELFAQWVKEIADGMHYLHQN---KVIHRDLKSPNILISAEDSIKICDFGTSHM------QKKMDSTMMSFCGTVSWMAPE 291          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: CST1_CAEEL (Serine/threonine-protein kinase cst-1 OS=Caenorhabditis elegans GN=cst-1 PE=2 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 1.052e-12
Identity = 58/199 (29.15%), Postives = 99/199 (49.75%), Query Frame = 1

Query:  217 EKEVDQFPLFSFSSVSSATGNFSAANKLGEGGFGTVYKGVIGQGE--IAVKRLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPE 807
            E   D F L S +        F    KLGEG +G+V+K +  +    +A+K++      +++E+  E S++ Q + K +VK  G   +  +  ++ EY    S+   +    +R+ L  +    +++   +GL YLH   +   IHRD+KA NILL+ D   K++DFG+A     G   D +    + I GT  +M+PE
Sbjct:   14 EGSSDGFKLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKV--PVDTDLQEIIKEISIMQQCKSKYVVKYYGSYFKHSDLWIVMEYCGAGSISDIM--RARRKPLSEQEISAVLRDTLKGLQYLHDLKK---IHRDIKAGNILLNTDGIAKLADFGVA-----GQLTDTMAKRNTVI-GTPFWMAPE 199          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: CDC2_CAEBR (Cell division control protein 2 homolog OS=Caenorhabditis briggsae GN=cdk-1 PE=3 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 1.052e-12
Identity = 49/155 (31.61%), Postives = 85/155 (54.84%), Query Frame = 1

Query:  277 NFSAANKLGEGGFGTVYKGVIG--QGEIAVKRLLGKSGQE--IKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIV 729
            +F+   K+GEG +G VYKG     Q  +A+K++  +S  E        E S++ ++QH N+V L    ++++   LI+E++ +  L  ++   +K E L   T       + Q + + HQ    R+IHRDLK  N+L+D+    K++DFG+AR +
Sbjct:   15 DFTKLEKIGEGTYGVVYKGRNRRTQAMVAMKKIRLESEDEGVPSTAVREISLLKELQHPNVVGLEAVIMQENRLYLIFEFL-SYDLKRYMDTLSKEEYLPSETLKSYTFQILQAMCFCHQR---RVIHRDLKPQNLLVDEKGAIKLADFGLARAI 165          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: CAD96_DROME (Tyrosine kinase receptor Cad96Ca OS=Drosophila melanogaster GN=Cad96Ca PE=2 SV=2)

HSP 1 Score: 74.3294 bits (181), Expect = 1.052e-12
Identity = 60/166 (36.14%), Postives = 82/166 (49.40%), Query Frame = 1

Query:  292 NKLGEGGFGTVYK-------GVIGQGEIAVKRLLGKSGQEI--KELKNEASVIAQVQ-HKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPT----------KREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIV 729
            N LGEG FG V++       G  G   +AVK L  +S  E+  K+L +E  V+  ++ H N+V LLGCC +KD   +I EY+    L  +L              K  +L        +  VA+G+ YL       IIHRDL A NIL+  D   K++DFG AR V
Sbjct:  474 NILGEGAFGQVWRCEATNINGNEGITTVAVKTLK-ESATEVDRKDLLSELEVMKSLEPHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKSNVLTSCDLTSFMYQVAKGMDYLTSRG---IIHRDLAARNILITDDHTCKVADFGFARDV 635          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: TYK2_MOUSE (Non-receptor tyrosine-protein kinase TYK2 OS=Mus musculus GN=Tyk2 PE=1 SV=2)

HSP 1 Score: 73.9442 bits (180), Expect = 1.129e-12
Identity = 54/158 (34.18%), Postives = 82/158 (51.90%), Query Frame = 1

Query:  298 LGEGGFGTVYKGVI-----GQGE-IAVKRLLGKSGQEIKE-LKNEASVIAQVQHKNLVKLLGCCIEKDERL--LIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGND 744
            LGEG FG V          G GE +AVK L    G +++   + E  ++  + H+++VK  GCC ++ E+   L+ EY+P  SL  +L     R  +     +   + + +G+ YLH       IHRDL A N+LLD D   KI DFG+A+ V  G++
Sbjct:  896 LGEGHFGKVSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYHEHIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYL----PRHCVGLAQLLLFAQQICEGMAYLHAQ---HYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHE 1046          

HSP 2 Score: 20.4014 bits (41), Expect = 1.129e-12
Identity = 8/13 (61.54%), Postives = 11/13 (84.62%), Query Frame = 2

Query:  821 EFFDKSDVFSFGV 859
            +F+  SDV+SFGV
Sbjct: 1070 KFYYASDVWSFGV 1082          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: SRMS_MOUSE (Tyrosine-protein kinase Srms OS=Mus musculus GN=Srms PE=1 SV=2)

HSP 1 Score: 73.1738 bits (178), Expect = 1.155e-12
Identity = 45/151 (29.80%), Postives = 84/151 (55.63%), Query Frame = 1

Query:  280 FSAANKLGEGGFGTVYKGV-IGQGEIAVKRLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIV 729
            F    KLGEG FG V++G+ +G   +AVK ++  +  ++ +L  E   +  ++H+ L++L   C   +   ++ E M   +L  +L   ++ + L     +     VA+G+ YL +    R++HRDL A N+L+  D+  K++DFG+AR++
Sbjct:  234 FVLRRKLGEGFFGEVWEGLWLGSIPVAVK-VIKSADMKLADLTKEIEALKSLRHERLIRLHAICSLGEPVYIVTELMGKGNLQVYL-GSSEGKALSLPHLLGFACQVAEGMSYLEER---RVVHRDLAARNVLVGDDLTCKVADFGLARLL 379          

HSP 2 Score: 21.1718 bits (43), Expect = 1.155e-12
Identity = 8/12 (66.67%), Postives = 10/12 (83.33%), Query Frame = 2

Query:  824 FFDKSDVFSFGV 859
            F  KSDV+SFG+
Sbjct:  407 FSQKSDVWSFGI 418          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: Y9963_DICDI (Probable serine/threonine-protein kinase DDB_G0272254 OS=Dictyostelium discoideum GN=DDB_G0272254 PE=3 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.374e-12
Identity = 57/179 (31.84%), Postives = 96/179 (53.63%), Query Frame = 1

Query:  295 KLGEGGFGTVYKGVIGQGEIAVKRLLG---KSGQE-IKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSL-DCFLFDPTKREI---LDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPE 807
            ++G+G F  V KG     ++AVK+L     K+ +E I+E K E  ++  +QH NLV   G  +  +   ++ E++P+ +L +     P++++    LD    + I   +A+G+ +LH  +   IIHRDLK+SN+L+DK  N KI+D G+AR        +     T    GT  + +PE
Sbjct: 1078 EIGKGHFSKVLKGNWKGKDVAVKKLNSNKDKAREEMIQEFKAEVELLGSLQHPNLVTCYGYSL--NPMCIVMEFLPSGNLFELIHSKPSEQQQSIKLDSTLILAIAFDIARGMQHLHTRN---IIHRDLKSSNLLMDKHFNIKIADLGIAR--------ETSFTQTMTTIGTVAWTAPE 1243          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: Y9848_DICDI (Probable serine/threonine-protein kinase DDB_G0272092 OS=Dictyostelium discoideum GN=DDB_G0272092 PE=2 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.374e-12
Identity = 53/171 (30.99%), Postives = 84/171 (49.12%), Query Frame = 1

Query:  298 LGEGGFGTVYKGVIGQGEIAVKRLLGKSGQ-EIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPE 807
            LG G  G VYKG     E+A+K L   + + +I E K E  +++ ++   +V   G  I KD+  ++ EY    SL   L D T +    W     +       L  LH ++  +++HRDLK+ N+L+ ++   KI DFG++R   G N           + GTY Y++PE
Sbjct:  607 LGTGASGKVYKGTFNGQEVAIKVLKSFTDKKDIAEFKKEFQIVSALRAPGVVYFHGAGI-KDKLCIVMEYCSRGSLYHILKDDTTQ--FTWDNFFNLGTQAINSLDSLHNWTP-QVLHRDLKSLNLLVTENWTVKICDFGLSRFDTGSN-----LETLGKLRGTYAYVAPE 768          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: TAO1A_XENLA (Serine/threonine-protein kinase TAO1-A OS=Xenopus laevis GN=taok1-A PE=2 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.374e-12
Identity = 55/184 (29.89%), Postives = 90/184 (48.91%), Query Frame = 1

Query:  280 FSAANKLGEGGFGTVY--KGVIGQGEIAVKRLL--GK-SGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPEYAL 816
            FS   ++G G FG VY       +  +A+K++   GK S ++ +++  E   + +++H N ++  GC + +    L+ EY    + D  L +  K+ + +      I  G  QGL YLH ++   +IHRD+KA NILL +    K++DFG A I    N             GT  +M+PE  L
Sbjct:   28 FSDLREIGHGSFGAVYFAHDASTREVVAIKKMSYSGKQSNEKWQDIVKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASD--LLEVHKKPLQEIEIAA-ITHGALQGLAYLHSHN---LIHRDIKAGNILLTEPGQVKLADFGSASIASPANS----------FVGTPYWMAPEVIL 195          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: STK36_PONAB (Serine/threonine-protein kinase 36 OS=Pongo abelii GN=STK36 PE=2 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.374e-12
Identity = 59/179 (32.96%), Postives = 87/179 (48.60%), Query Frame = 1

Query:  298 LGEGGFGTVYKG--VIGQGEIAVKRL--LGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKG-VAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPEYALE 819
            +GEG FG VYKG        +A+K +  LG+S +E++ L+ E  ++  ++H N+V +L       E +++ +Y   + L     D    E      +VQ I   +   L YLH +   RI+HRD+K  NILL K    K+ DFG AR +             + I GT  YMSPE   E
Sbjct:   10 IGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELLQILEDDGKLPE-----DQVQAIAAQLVSALYYLHSH---RILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNT------MVLTSIKGTPLYMSPELVEE 174