EY728231

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: STK25_BOVIN (Serine/threonine-protein kinase 25 OS=Bos taurus GN=STK25 PE=2 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.374e-12
Identity = 53/179 (29.61%), Postives = 97/179 (54.19%), Query Frame = 1

Query:  280 FSAANKLGEGGFGTVYKGVIGQGE--IAVKRL-LGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPE 807
            F+  +++G+G FG VYKG+  + +  +A+K + L ++  EI++++ E +V++Q     + +  G  ++  +  +I EY+   S      D  K   L+      I++ + +GL YLH     R IHRD+KA+N+LL +  + K++DFG+A     G   D      + + GT  +M+PE
Sbjct:   20 FTKLDRIGKGSFGEVYKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSA----LDLLKPGPLEETYIATILREILKGLDYLHSE---RKIHRDIKAANVLLSEQGDVKLADFGVA-----GQLTDTQIKRNTFV-GTPFWMAPE 185          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: ROS_RAT (Proto-oncogene tyrosine-protein kinase ROS OS=Rattus norvegicus GN=Ros1 PE=2 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.374e-12
Identity = 64/222 (28.83%), Postives = 106/222 (47.75%), Query Frame = 1

Query:  217 EKEVDQFPLFSFSSVSSATGNFSAANKLGEGGFGTVYKG----VIGQG----EIAVKRLL-GKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFL----FDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLD-KDMNP----KISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPEYALEGIF 828
            ++E++  P F    +S           LG G FG VY+G    ++G+G    ++AVK L  G + QE  E   EA ++++  H N++K LG C+  + + +I E M    L  +L           +L     V++   +++G +YL Q   +  IHRDL A N L+  KD       KI DFG+AR ++  +   +       +     +M+PE  ++GIF
Sbjct: 1923 QEEIESLPAFPREKLSLRL-------LLGSGAFGEVYEGTAVDILGRGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPNILKQLGVCLLSEPQYIILELMEGGDLLSYLRKARGTTLSGPLLTLADLVELCVDISKGCVYLEQ---MHFIHRDLAARNCLVSVKDYTSPRVVKIGDFGLAREIYKHDYYRKRGEGLLPVR----WMAPENLMDGIF 2130          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: RIPK2_MOUSE (Receptor-interacting serine/threonine-protein kinase 2 OS=Mus musculus GN=Ripk2 PE=2 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.374e-12
Identity = 38/112 (33.93%), Postives = 66/112 (58.93%), Query Frame = 1

Query:  388 EIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMAR 723
            E  ++  EA ++ + +   ++ +LG C E +   ++ EYMPN SL+  L   T+   + W  R +I+  +A G+ YLH  +   ++H DLK  NILLD + + KI+DFG+++
Sbjct:   59 ERNDILREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDIAWPLRFRILHEIALGVNYLHNMN-PPLLHHDLKTQNILLDNEFHVKIADFGLSK 169          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: RIPK1_HUMAN (Receptor-interacting serine/threonine-protein kinase 1 OS=Homo sapiens GN=RIPK1 PE=1 SV=3)

HSP 1 Score: 73.9442 bits (180), Expect = 1.374e-12
Identity = 57/201 (28.36%), Postives = 94/201 (46.77%), Query Frame = 1

Query:  238 PLFSFSSVSSATGNFSAANKLGEGGFGTVYKGVIGQGEIAVKRLLGKSGQEIKE---LKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGG-------NDXDELXXHTSXISGTYGYMSPEY 810
            P  S + +   + +F  + +L  GGFG V         + + + + K    I+    L  EA ++ +++H  +VKLLG  IE+ +  L+ EYM   +L   L       +     + +II  + +G+ YLH      +IH+DLK  NIL+D D + KI+D G+A             N+  E+        GT  YM+PE+
Sbjct:    3 PDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPL---SVKGRIILEIIEGMCYLHGKG---VIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAPEH 197          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: PYK2_DICDI (Dual specificity protein kinase pyk2 OS=Dictyostelium discoideum GN=splB PE=2 SV=2)

HSP 1 Score: 73.9442 bits (180), Expect = 1.374e-12
Identity = 51/148 (34.46%), Postives = 80/148 (54.05%), Query Frame = 1

Query:  295 KLGEGGFGTVYKGVIGQGEIAVKRL--LGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDP---TKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMAR 723
            K+GEG F  V++G      +A+K+L  +G   Q  +    E   + +  H+N+V  +G C +     +I EYM   SL   L +P   T +    +   +++   +A GLL+LH    + I+HRDL + NILLD+  N KISDFG++R
Sbjct:  858 KVGEGAFSEVWEGWWKGIHVAIKKLKIIGDEEQFKERFIREVQNLKKGNHQNIVMFIGACYKP--ACIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVLKMATDMALGLLHLHS---ITIVHRDLTSQNILLDELGNIKISDFGLSR 1000          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: PLK4_DROGR (Serine/threonine-protein kinase PLK4 OS=Drosophila grimshawi GN=SAK PE=3 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.374e-12
Identity = 56/195 (28.72%), Postives = 98/195 (50.26%), Query Frame = 1

Query:  241 LFSFSSVSSATGNFSAANKLGEGGFGTVYKG--VIGQGEIAVK----RLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPE 807
            +  F +       +   + LG+GGF  VYK   +  Q  +A+K    +L+  SG   + ++ E  + ++++H ++++L     + +   L+ E   N  L  ++    KR   +      I++ V  GLLYLH ++   I+HRD+  SN+LL +DM+ KI+DFG+A  +      DE       + GT  Y+SPE
Sbjct:    1 MLPFRNYGETIDEYEVQHLLGKGGFACVYKAKCLRTQQNVAIKMIDKKLIQGSGLSSR-VRQEVEIHSRLKHPSVLQLHTFFQDGNYVYLVLELADNGELHRYMNQQMKRPFTEQEAS-SILRQVVDGLLYLHSHN---IMHRDISLSNLLLSRDMHVKIADFGLATQL---KRPDE---RHMTMCGTPNYISPE 184          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: FPS_DROME (Tyrosine-protein kinase Fps85D OS=Drosophila melanogaster GN=Fps85D PE=1 SV=3)

HSP 1 Score: 73.9442 bits (180), Expect = 1.374e-12
Identity = 47/146 (32.19%), Postives = 79/146 (54.11%), Query Frame = 1

Query:  295 KLGEGGFGTVYKGVIGQG--EIAVKRL-LGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKREILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMAR 723
            ++G G FG VYK  +     ++AVK   +    ++ ++   E  ++ Q  H N+VKL+G C++K   +++ E +   SL  +L   +    L  R ++ + +  A G+ YL   +    IHRDL A N L+D + + KISDFGM+R
Sbjct: 1068 RIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNG--LTTRQQMGMCRDAAAGMRYLESKN---CIHRDLAARNCLVDLEHSVKISDFGMSR 1208          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: ERBB2_RAT (Receptor tyrosine-protein kinase erbB-2 OS=Rattus norvegicus GN=Erbb2 PE=1 SV=3)

HSP 1 Score: 73.9442 bits (180), Expect = 1.374e-12
Identity = 64/189 (33.86%), Postives = 97/189 (51.32%), Query Frame = 1

Query:  298 LGEGGFGTVYKGV-IGQGE-----IAVKRLLGKSGQEI-KELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTKR----EILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVFGGNDXDELXXHTSXISGTYGYMSPEYALEGIFR 831
            LG G FGTVYKG+ I  GE     +A+K L   +  +  KE+ +EA V+A V    + +LLG C+    +L + + MP   L   + +   R    ++L+W  ++      A+G+ YL     VR++HRDL A N+L+    + KI+DFG+AR++    D DE   H         +M    ALE I R
Sbjct:  728 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQL-VTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQI------AKGMSYLED---VRLVHRDLAARNVLVKSPNHVKITDFGLARLL----DIDETEYHADGGKVPIKWM----ALESILR 898          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: ROCO8_DICDI (Probable serine/threonine-protein kinase roco8 OS=Dictyostelium discoideum GN=roco8 PE=3 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 1.450e-12
Identity = 42/136 (30.88%), Postives = 76/136 (55.88%), Query Frame = 1

Query:  343 QGEIAVKRLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFLFDPTK-REILDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILL------DKDMNPKISDFGMARIV 729
            QGE ++ ++       I E + E  +++ + H N+V + G C E     ++ EYM   SL  FL    +  ++LDW+  ++I+  +A G+ +LH  +   ++HRDLK+ NILL        +++ K+SDFG++R +
Sbjct: 1620 QGEDSMNQISSGKLNAINEFRREVWLMSGLSHSNIVLMKGFCFE--PYAIVMEYMDIGSLSSFLKKKKEDGQVLDWQMLLKIVTDIASGMAFLHNIT-PPLVHRDLKSPNILLASHPTNPNEISAKVSDFGLSRSI 1752          

HSP 2 Score: 21.9422 bits (45), Expect = 1.450e-12
Identity = 7/13 (53.85%), Postives = 12/13 (92.31%), Query Frame = 2

Query:  821 EFFDKSDVFSFGV 859
            E+ +KSD++SFG+
Sbjct: 1776 EYNEKSDIYSFGM 1788          

BLAST of EY728231 vs. ExPASy Swiss-Prot
Match: NTRK1_CHICK (High affinity nerve growth factor receptor (Fragment) OS=Gallus gallus GN=NTRK1 PE=2 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 1.482e-12
Identity = 50/165 (30.30%), Postives = 85/165 (51.52%), Query Frame = 1

Query:  295 KLGEGGFGTVYKG----VIGQGE---IAVKRLLGKSGQEIKELKNEASVIAQVQHKNLVKLLGCCIEKDERLLIYEYMPNKSLDCFL--FDPTKREI----------LDWRTRVQIIKGVAQGLLYLHQYSRVRIIHRDLKASNILLDKDMNPKISDFGMARIVF 732
            +LGEG FG V+      ++ + E   +AVK L   +     + + EA ++  +QH+++VK  G C E D  ++++EYM +  L+ FL    P  + +          L     +QI   +A G++YL   + +  +HRDL   N L+  D+  KI DFGM+R ++
Sbjct:  498 ELGEGAFGKVFLAECSHLLPEQEKTLVAVKALKEVTENARLDFQREAELLTVLQHEHIVKFYGVCTEGDPLIMVFEYMKHGDLNRFLRSHGPDAKILDQGQGQPCGQLTLSHMLQIATQIASGMVYL---ASLHFVHRDLATRNCLVGHDLVVKIGDFGMSRDIY 659          

HSP 2 Score: 20.4014 bits (41), Expect = 1.482e-12
Identity = 7/14 (50.00%), Postives = 12/14 (85.71%), Query Frame = 2

Query:  818 KEFFDKSDVFSFGV 859
            ++F  +SD++SFGV
Sbjct:  685 RKFTTESDIWSFGV 698