EY753292

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1CD_MOUSE (Aldo-keto reductase family 1 member C13 OS=Mus musculus GN=Akr1c13 PE=1 SV=2)

HSP 1 Score: 88.5817 bits (218), Expect = 4.953e-17
Identity = 51/131 (38.93%), Postives = 74/131 (56.49%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPEN------LLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            CT   P+ V  AL+ +L+ L++DYVDLY++H+P  MK G   F P N      L  +D   TW  +E   D+G  ++IGV NF+ ++L  +L     +  P  NQVECH    Q+KL  +C+SK + L  Y
Sbjct:   87 CTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDNDF-PVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAY 216          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: DIDH_RAT (3-alpha-hydroxysteroid dehydrogenase OS=Rattus norvegicus GN=Akr1c9 PE=1 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 8.448e-17
Identity = 48/125 (38.40%), Postives = 71/125 (56.80%), Query Frame = 2

Query:  452 PKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPEN-----LLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            P+ V   L+ TL+  ++DYVDLY+IH+P  ++ G + F  +         +DI  TW AME   D+G A++IGV NF+ ++L  +L     +  P  NQVECH    Q K+  +CKSK + L  Y
Sbjct:   92 PELVRTCLEKTLKSTQLDYVDLYIIHFPMALQPGDIFFPRDEHGKLLFETVDICDTWEAMEKCKDAGLAKSIGVSNFNCRQLERILNKPGLKYKPVCNQVECHLYLNQSKMLDYCKSKDIILVSY 216          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AKC1H_RAT (Aldo-keto reductase family 1 member C18 OS=Rattus norvegicus GN=Akr1c18 PE=1 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 1.441e-16
Identity = 52/135 (38.52%), Postives = 73/135 (54.07%), Query Frame = 2

Query:  440 TDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLP-----------LDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVP--PAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            T   P+ V  +L+N+L+ L +DYVDLYLIH+P  +K G      + LLP           +D+  TW AME   D+G A++IGV NF+ ++L  +L    +   P  NQVECH    Q KL  +CK   + L  Y
Sbjct:   88 TSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPG------DELLPQDEHGNLILDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHLYLNQSKLLAYCKMNDIVLVAY 216          

HSP 2 Score: 76.2554 bits (186), Expect = 2.544e-13
Identity = 36/78 (46.15%), Postives = 51/78 (65.38%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTWQADPGVVGNAVD---VAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            ELN G  +P +G GT+  +  +   +++   +AI  G+RHIDC+ LY NE+EIG  +    EDG VKRED++ TSKLW
Sbjct:    9 ELNDGHSIPVLGFGTYATEENLRKKSMESTKIAIDVGFRHIDCSHLYQNEEEIGQAIVSKIEDGTVKREDIFYTSKLW 86          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AKC1H_MOUSE (Aldo-keto reductase family 1 member C18 OS=Mus musculus GN=Akr1c18 PE=2 SV=2)

HSP 1 Score: 87.0409 bits (214), Expect = 1.441e-16
Identity = 51/129 (39.53%), Postives = 74/129 (57.36%), Query Frame = 2

Query:  440 TDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPE---NLL--PLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            T   P+ V  +L+N+L+ L +DYVDLYLIH+P  +K G+     +   NL+   +D+  TW AME   D+G A++IGV NF+ ++L  +L     +  P  NQVECH    Q KL  +CK   + L  Y
Sbjct:   88 TSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAY 216          

HSP 2 Score: 72.7886 bits (177), Expect = 2.812e-12
Identity = 35/78 (44.87%), Postives = 50/78 (64.10%), Query Frame = 1

Query:   64 ELNTGAKMPSVGLGTWQADPGVVGNAVD---VAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            ELN G  +P +G GT+  +  +   +++   +AI  G+ HIDC+ LY NE+EIG  +    EDG VKRED++ TSKLW
Sbjct:    9 ELNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIGQAILSKIEDGTVKREDIFYTSKLW 86          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: P100_LEIMA (Probable reductase OS=Leishmania major GN=P100/11E PE=2 SV=2)

HSP 1 Score: 86.2705 bits (212), Expect = 2.458e-16
Identity = 48/112 (42.86%), Postives = 61/112 (54.46%), Query Frame = 2

Query:  470 ALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            A + + Q L +DY+DLYLIHWP    +G    + E    LD   +WRA E LY   K RAIGV NF    L D+L +  V P VNQVE HP   Q  L  FC +K + +  +
Sbjct:   93 AFEESRQKLGVDYIDLYLIHWP----RGKDILSKEGKKYLD---SWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAW 197          

HSP 2 Score: 70.8626 bits (172), Expect = 1.069e-11
Identity = 38/75 (50.67%), Postives = 49/75 (65.33%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPG-VVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            L+ G KMP  GLG WQ+  G V  NAV+ A+ AGYRHID A +Y NE+ +G  L+       V RED++IT+KLW
Sbjct:   11 LSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGLRA----SGVPREDVFITTKLW 81          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AKCL2_MACFA (1,5-anhydro-D-fructose reductase OS=Macaca fascicularis GN=AKR1E2 PE=2 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 2.081e-15
Identity = 38/68 (55.88%), Postives = 49/68 (72.06%), Query Frame = 1

Query:   85 MPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            +P+VGL  W+A PG V  AV VAI AGYRH +CA  Y NEKE+G  ++   ++G V+REDL+I SKLW
Sbjct:    4 IPAVGLSCWKASPGKVTEAVKVAIDAGYRHFNCAYFYHNEKEVGAGIRYKIKEGAVRREDLFIASKLW 71          

HSP 2 Score: 78.5666 bits (192), Expect = 5.125e-14
Identity = 58/170 (34.12%), Postives = 81/170 (47.65%), Query Frame = 2

Query:  395 QGMFVLSKFVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENL--------------------LPLD-----IPS------TWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIA--RVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            + +F+ SK      CT      V  A   +L+ L+++Y+DLYLIHWP       +GF P +                     LPLD     IP       TW AME L  +G  + IGV NF+ ++L  LL     R  P  NQ+ECHP   Q+ L +FC+S+GV ++ Y
Sbjct:   62 EDLFIASKLW----CTCHKKSLVKTACRRSLKALKLNYLDLYLIHWP-------MGFKPPHPEWIMSCSELSFCLSHPGVHDLPLDESDMVIPGDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPVTNQIECHPYLTQKNLISFCQSRGVSVTAY 220          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: DKGA_YERPE (2,5-diketo-D-gluconic acid reductase A OS=Yersinia pestis GN=dkgA PE=3 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 6.054e-15
Identity = 42/102 (41.18%), Postives = 58/102 (56.86%), Query Frame = 2

Query:  467 EALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENLLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTF 772
            +AL+ +LQ L++DYVDLYLIHWP   +   V             S WR +  L + G  R+IGVCNF    L  L++   + P VNQ+E HP  QQ++LH +
Sbjct:   87 QALETSLQKLQLDYVDLYLIHWPDPKQDHYV-------------SAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIELHPLLQQRQLHAW 175          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: S6PD_MALDO (NADP-dependent D-sorbitol-6-phosphate dehydrogenase OS=Malus domestica GN=S6PDH PE=2 SV=1)

HSP 1 Score: 81.2629 bits (199), Expect = 7.907e-15
Identity = 43/119 (36.13%), Postives = 64/119 (53.78%), Query Frame = 2

Query:  461 VPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVG-----FNPENLLPLDIP----STWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIARVPPAVNQVECHPSWQQQKLHTFCKSKGV 790
            V EA  N+L+ L+IDY+DLYL+H+P   K  ++G        + +L +D+      TW  ME     G  R+IG+ N+      D L  +++ PAV+Q E HP +Q+  L  FC   GV
Sbjct:   86 VVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGV 204          

HSP 2 Score: 75.485 bits (184), Expect = 4.339e-13
Identity = 33/74 (44.59%), Postives = 51/74 (68.92%), Query Frame = 1

Query:   67 LNTGAKMPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            L++G +MP +GLG W+ +   +   +  AIK GYRH DCA  Y +E ++G  L + F+ G+VKRE+L+IT+K+W
Sbjct:    6 LSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFKTGLVKREELFITTKIW 79          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AKCL2_HUMAN (1,5-anhydro-D-fructose reductase OS=Homo sapiens GN=AKR1E2 PE=1 SV=2)

HSP 1 Score: 80.8777 bits (198), Expect = 1.033e-14
Identity = 36/68 (52.94%), Postives = 49/68 (72.06%), Query Frame = 1

Query:   85 MPSVGLGTWQADPGVVGNAVDVAIKAGYRHIDCARLYLNEKEIGFVLKKLFEDGVVKREDLWITSKLW 288
            +P+VGL +W+A PG V  AV  AI AGYRH DCA  Y NE+E+G  ++   ++G V+REDL+I +KLW
Sbjct:    4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLW 71          

HSP 2 Score: 76.2554 bits (186), Expect = 2.544e-13
Identity = 55/156 (35.26%), Postives = 75/156 (48.08%), Query Frame = 2

Query:  437 CTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPENL--------------------LPLD-----IPS------TWRAMEALYDSGKARAIGVCNFSTKKLGDLLEIA--RVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            CT      V  A   +L+ L+++Y+DLYLIHWP       +GF P +                     LPLD     IPS      TW AME L  +G  + IGV NF+ ++L  LL     R  P  NQ+ECHP   Q+ L +FC+S+ V ++ Y
Sbjct:   72 CTCHKKSLVETACRKSLKALKLNYLDLYLIHWP-------MGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAY 220          

BLAST of EY753292 vs. ExPASy Swiss-Prot
Match: AK1CD_MESAU (Aldo-keto reductase family 1 member C13 OS=Mesocricetus auratus GN=AKR1C13 PE=1 SV=1)

HSP 1 Score: 80.8777 bits (198), Expect = 1.033e-14
Identity = 48/144 (33.33%), Postives = 77/144 (53.47%), Query Frame = 2

Query:  395 QGMFVLSKFVMIHRCTDLAPKDVPEALDNTLQDLRIDYVDLYLIHWPARMKKGSVGFNPEN-----LLPLDIPSTWRAMEALYDSGKARAIGVCNFSTKKLGDLLEI--ARVPPAVNQVECHPSWQQQKLHTFCKSKGVHLSGY 805
            + MF+ +K      CT   P+ V  +L+     L++++VDL+++H+P  MK G   F  +      L  +D  +TW A+E   D+G  ++IGV NF+ ++L  +L     +  P  NQVECH    Q KL  +CKSK + L  +
Sbjct:   77 EDMFITTKLW----CTCFQPELVRPSLEKXXXKLQLEHVDLFIMHYPVPMKAGDNDFPLDEQGKLLLDTVDFCATWEALEKXXDAGLVKSIGVSNFNMRQLERILNKPGLKYKPVCNQVECHVYNNQSKLLDYCKSKDIVLVAF 216