EY720507

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: M3K4_HUMAN (Mitogen-activated protein kinase kinase kinase 4 OS=Homo sapiens GN=MAP3K4 PE=1 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 4.247e-31
Identity = 70/174 (40.23%), Postives = 102/174 (58.62%), Query Frame = 2

Query:   11 DHLYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTGLSYEL-----SLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFE-GPQAMFKV-LNSTPPIPEMLSSEGEGFSS 511
            + +YI++EY   G++    R     + E ++  +++QI   +  LH    +HRDIKGAN+ + +SG++KL DFG    L   +  +     S  G+  +MAPEV+    + +G+ R    ADIWSLGC VIEM+TGK PW E+E   Q M+KV +   PPIPE LS EG+ F S
Sbjct: 1412 EEMYIFMEYCDEGTLEEVSRL---GLQEHVIRLYSKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVI-TRAKGEGHGRA---ADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPPIPERLSPEGKDFLS 1578          

HSP 2 Score: 39.2762 bits (90), Expect = 4.247e-31
Identity = 16/31 (51.61%), Postives = 21/31 (67.74%), Query Frame = 3

Query:  489 PRGKDFLRHCLRRNPVERPSACMLLEHPFIR 581
            P GKDFL HCL  +P  R +A  LL+H F++
Sbjct: 1571 PEGKDFLSHCLESDPKMRWTASQLLDHSFVK 1601          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: M3K4_MOUSE (Mitogen-activated protein kinase kinase kinase 4 OS=Mus musculus GN=Map3k4 PE=1 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 1.221e-30
Identity = 71/174 (40.80%), Postives = 102/174 (58.62%), Query Frame = 2

Query:   11 DHLYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTGLSYEL-----SLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFE-GPQAMFKV-LNSTPPIPEMLSSEGEGFSS 511
            + +YI++EY   G++    R     + E ++  +T+QI   +  LH    +HRDIKGAN+ + +SG++KL DFG    L   +  +     S  G+  +MAPEV+    + +G+ R    ADIWSLGC VIEM+TGK PW E+E   Q M+KV +   PPIPE LS EG+ F S
Sbjct: 1402 EEMYIFMEYCDEGTLEEVSRL---GLQEHVIRLYTKQITVAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVI-TRAKGEGHGRA---ADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPPIPERLSPEGKAFLS 1568          

HSP 2 Score: 35.8094 bits (81), Expect = 1.221e-30
Identity = 15/31 (48.39%), Postives = 20/31 (64.52%), Query Frame = 3

Query:  489 PRGKDFLRHCLRRNPVERPSACMLLEHPFIR 581
            P GK FL HCL  +P  R +A  LL+H F++
Sbjct: 1561 PEGKAFLSHCLESDPKIRWTASQLLDHAFVK 1591          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: STK4_SQUAC (Serine/threonine-protein kinase 3/4 OS=Squalus acanthias GN=STK4 PE=2 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 1.240e-30
Identity = 66/167 (39.52%), Postives = 96/167 (57.49%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTG-LSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPI---PEMLSSEGEGF 505
            L+I +EY   GS++  +R     +TE  +    +  L GL YLH    IHRDIK  N+L++  G  KLADFG+   LT  ++   ++ G+P+WMAPEV    IQ+ G + V   ADIWSLG + IEM  GKPP+++    +A+F +  + PP    PE+ + E   F
Sbjct:  100 LWIVMEYCGAGSVSDLIRIRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNNEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEV----IQEIGYNCV---ADIWSLGISAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWTDEFTDF 259          

HSP 2 Score: 41.2022 bits (95), Expect = 1.240e-30
Identity = 16/29 (55.17%), Postives = 23/29 (79.31%), Query Frame = 3

Query:  501 DFLRHCLRRNPVERPSACMLLEHPFIRNA 587
            DF++ CL +NP +R +A  LL+HPFI+NA
Sbjct:  258 DFVKQCLVKNPEQRAAATQLLQHPFIKNA 286          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: M3K2_MOUSE (Mitogen-activated protein kinase kinase kinase 2 OS=Mus musculus GN=Map3k2 PE=1 SV=2)

HSP 1 Score: 133.265 bits (334), Expect = 1.279e-30
Identity = 77/172 (44.77%), Postives = 105/172 (61.05%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHL-------TGLSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLN--STPPIPEMLSSEGEGF 505
            L I++E    GSI   ++ + G +TE++   +TRQIL G+ YLHS   +HRDIKGAN+L D++G +KL DFG  K L       TG+    S+ G+PYWM+PEV    I  +G  R    ADIWS+ CTV+EMLT KPPW+EFE   A+FK+    + P +P  +S     F
Sbjct:  433 LSIFMELSPGGSIKDQLKAY-GALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMK---SVTGTPYWMSPEV----ISGEGYGR---KADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDF 593          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: CST1_CAEEL (Serine/threonine-protein kinase cst-1 OS=Caenorhabditis elegans GN=cst-1 PE=2 SV=1)

HSP 1 Score: 117.472 bits (293), Expect = 1.614e-30
Identity = 68/167 (40.72%), Postives = 95/167 (56.89%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTG-LSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPI---PEMLSSEGEGF 505
            L+I +EY   GSI+  +R     ++E  +    R  L GL YLH    IHRDIK  N+L++  G+ KLADFG+   LT  ++   ++ G+P+WMAPEV++ +I  D        ADIWSLG T IEM  G+PP+S+    +A+F +    PP    PE  SSE   F
Sbjct:  103 LWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIE-EIGYDTK------ADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDF 262          

HSP 2 Score: 36.965 bits (84), Expect = 1.614e-30
Identity = 16/29 (55.17%), Postives = 20/29 (68.97%), Query Frame = 3

Query:  501 DFLRHCLRRNPVERPSACMLLEHPFIRNA 587
            DF+R CL + P ER +A  L EH FI+NA
Sbjct:  261 DFIRSCLIKKPEERKTALRLCEHTFIKNA 289          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: STK3_MOUSE (Serine/threonine-protein kinase 3 OS=Mus musculus GN=Stk3 PE=1 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 1.614e-30
Identity = 67/167 (40.12%), Postives = 96/167 (57.49%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTG-LSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPI---PEMLSSEGEGF 505
            L+I +EY   GS++  +R     +TE  +    +  L GL YLH    IHRDIK  N+L++  G  KLADFG+   LT  ++   ++ G+P+WMAPEV    IQ+ G + V   ADIWSLG T IEM  GKPP+++    +A+F +  + PP    PE+ S +   F
Sbjct:   95 LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEV----IQEIGYNCV---ADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDF 254          

HSP 2 Score: 38.891 bits (89), Expect = 1.614e-30
Identity = 15/29 (51.72%), Postives = 23/29 (79.31%), Query Frame = 3

Query:  501 DFLRHCLRRNPVERPSACMLLEHPFIRNA 587
            DF++ CL ++P +R +A  LL+HPFI+NA
Sbjct:  253 DFVKKCLVKSPEQRATATQLLQHPFIKNA 281          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: STK3_RAT (Serine/threonine-protein kinase 3 OS=Rattus norvegicus GN=Stk3 PE=1 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 1.615e-30
Identity = 67/167 (40.12%), Postives = 96/167 (57.49%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTG-LSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPI---PEMLSSEGEGF 505
            L+I +EY   GS++  +R     +TE  +    +  L GL YLH    IHRDIK  N+L++  G  KLADFG+   LT  ++   ++ G+P+WMAPEV    IQ+ G + V   ADIWSLG T IEM  GKPP+++    +A+F +  + PP    PE+ S +   F
Sbjct:   95 LWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEV----IQEIGYNCV---ADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDF 254          

HSP 2 Score: 38.891 bits (89), Expect = 1.615e-30
Identity = 15/29 (51.72%), Postives = 23/29 (79.31%), Query Frame = 3

Query:  501 DFLRHCLRRNPVERPSACMLLEHPFIRNA 587
            DF++ CL ++P +R +A  LL+HPFI+NA
Sbjct:  253 DFVKKCLVKSPEQRATATQLLQHPFIKNA 281          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: STK3_HUMAN (Serine/threonine-protein kinase 3 OS=Homo sapiens GN=STK3 PE=1 SV=2)

HSP 1 Score: 113.235 bits (282), Expect = 2.102e-30
Identity = 66/167 (39.52%), Postives = 95/167 (56.89%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTG-LSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPI---PEMLSSEGEGF 505
            L+I +EY   GS++  +R     + E  +    +  L GL YLH    IHRDIK  N+L++  G  KLADFG+   LT  ++   ++ G+P+WMAPEV    IQ+ G + V   ADIWSLG T IEM  GKPP+++    +A+F +  + PP    PE+ S +   F
Sbjct:   95 LWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEV----IQEIGYNCV---ADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDF 254          

HSP 2 Score: 40.817 bits (94), Expect = 2.102e-30
Identity = 16/29 (55.17%), Postives = 23/29 (79.31%), Query Frame = 3

Query:  501 DFLRHCLRRNPVERPSACMLLEHPFIRNA 587
            DF++ CL +NP +R +A  LL+HPFI+NA
Sbjct:  253 DFVKKCLVKNPEQRATATQLLQHPFIKNA 281          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: BYR2_SCHPO (Protein kinase byr2 OS=Schizosaccharomyces pombe GN=byr2 PE=1 SV=1)

HSP 1 Score: 129.798 bits (325), Expect = 4.622e-30
Identity = 77/174 (44.25%), Postives = 101/174 (58.05%), Query Frame = 2

Query:   11 DHLYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHL--------TGLSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKV-LNSTPPIPEMLSSEGEGF 505
            DHL I+LEYV  GS+   +  + G   E++V NF +Q L GL YLHS   +HRDIKGAN+LVD  G +K++DFGI K L        TG     S +GS +WMAPEV++  +  +         DIWSLGC VIEMLT K P+   +  QA+F++  N  P  P  +SS    F
Sbjct:  470 DHLNIFLEYVPGGSVAGLLTMY-GSFEETLVKNFIKQTLKGLEYLHSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTG-GARPSFQGSSFWMAPEVVKQTMHTE-------KTDIWSLGCLVIEMLTSKHPYPNCDQMQAIFRIGENILPEFPSNISSSAIDF 634          

HSP 2 Score: 23.0978 bits (48), Expect = 4.622e-30
Identity = 11/26 (42.31%), Postives = 14/26 (53.85%), Query Frame = 3

Query:  501 DFLRHCLRRNPVERPSACMLLEHPFI 578
            DFL      +   RP+A  LL HPF+
Sbjct:  633 DFLEKTFAIDCNLRPTASELLSHPFV 658          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: Y4251_DICDI (Probable serine/threonine-protein kinase DDB_G0284251 OS=Dictyostelium discoideum GN=DDB_G0284251 PE=3 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 1.024e-29
Identity = 69/161 (42.86%), Postives = 96/161 (59.63%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTGLS-YELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNST-PPIPEMLSSE 493
            L   LEYV  GS+ R V E  G ++E +   +  Q+L GLAYLHS   IHRDIK +N+L+   GV+KLADFG+   +   S    S+ G+PYWMAPE ++           +  +DIWSLG T+IE+LTG PP+   +   AMF++++   PP P  +S E
Sbjct:  108 LNFILEYVENGSL-RDVIEKFGPLSEELCIIYLYQMLQGLAYLHSNKVIHRDIKASNILITKEGVIKLADFGVASQIDSESQLRFSVVGTPYWMAPESIEIS-------GCSSASDIWSLGSTMIELLTGNPPYYTLQPMAAMFRIVSDQHPPFPTDISKE 260          

HSP 2 Score: 27.7202 bits (60), Expect = 1.024e-29
Identity = 9/24 (37.50%), Postives = 17/24 (70.83%), Query Frame = 3

Query:  501 DFLRHCLRRNPVERPSACMLLEHP 572
            D+ +   +++P +RP+A  LL+HP
Sbjct:  263 DYFQQSFKKDPTQRPTAQELLQHP 286