EY720507

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: M3K5_HUMAN (Mitogen-activated protein kinase kinase kinase 5 OS=Homo sapiens GN=MAP3K5 PE=1 SV=1)

HSP 1 Score: 122.865 bits (307), Expect = 1.729e-27
Identity = 73/168 (43.45%), Postives = 101/168 (60.12%), Query Frame = 2

Query:   23 IYLEYVHPGSINRYVREHCGDI--TESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDA-SGVVKLADFGIGKHLTGLS-YELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQ-AMFKV--LNSTPPIPEMLSSEGEGF 505
            I++E V  GS++  +R   G +   E  +  +T+QIL GL YLH    +HRDIKG N+L++  SGV+K++DFG  K L G++    +  G+  +MAPE++       G       ADIWSLGCT+IEM TGKPP+ E   PQ AMFKV      P IPE +S+E + F
Sbjct:  752 IFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDK-----GPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAF 914          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: STK10_MOUSE (Serine/threonine-protein kinase 10 OS=Mus musculus GN=Stk10 PE=1 SV=1)

HSP 1 Score: 106.686 bits (265), Expect = 1.985e-27
Identity = 59/152 (38.82%), Postives = 86/152 (56.58%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGI-GKHLTGLSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPP 469
            L+I +E+   G+++  + E    +TE  +    RQ+L  L +LH    IHRD+K  N+L+   G ++LADFG+  K+L  L    S  G+PYWMAPEV+  +  KD  +     ADIWSLG T+IEM   +PP  E    + + K+  S PP
Sbjct:  106 LWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVLCETMKDAPYDYK--ADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPP 255          

HSP 2 Score: 37.3502 bits (85), Expect = 1.985e-27
Identity = 15/27 (55.56%), Postives = 20/27 (74.07%), Query Frame = 3

Query:  498 KDFLRHCLRRNPVERPSACMLLEHPFI 578
            +DFL+  L +NP  RPSA  LL+HPF+
Sbjct:  268 RDFLKIALDKNPETRPSAAQLLQHPFV 294          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: SVKA_DICDI (Serine/threonine-protein kinase svkA OS=Dictyostelium discoideum GN=svkA PE=1 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 2.006e-27
Identity = 66/161 (40.99%), Postives = 94/161 (58.39%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTG-LSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPIPEMLSSEG 496
            L+I +EY+  GS+   ++   G   E  +    R++L GL YLHS   IHRDIK AN+L+ ASG VKLADFG+   LT  ++   +  G+P+WMAPEV    I++ G       ADIWS+G T +EM  G+PP ++    +A+F +    PP  E   S+G
Sbjct:   83 LWIIMEYLAGGSVLDLMKP--GPFDEGYIAIILRELLKGLEYLHSEGKIHRDIKAANVLLSASGDVKLADFGVSGQLTDQMTKRNTFVGTPFWMAPEV----IKQTGYDS---KADIWSMGITALEMAKGEPPRADLHPMRALFLIPKDPPPTLEGNFSKG 234          

HSP 2 Score: 31.9574 bits (71), Expect = 2.006e-27
Identity = 14/30 (46.67%), Postives = 21/30 (70.00%), Query Frame = 3

Query:  498 KDFLRHCLRRNPVERPSACMLLEHPFIRNA 587
            K+F   CL ++P +RP+A  LL+H FI+ A
Sbjct:  236 KEFCALCLNKDPNQRPTAKDLLKHKFIKAA 265          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: M4K4_HUMAN (Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4 PE=1 SV=2)

HSP 1 Score: 107.457 bits (267), Expect = 2.574e-27
Identity = 59/155 (38.06%), Postives = 87/155 (56.13%), Query Frame = 2

Query:   11 DHLYIYLEYVHPGSINRYVREHCGD-ITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHL-TGLSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPP 469
            D L++ +E+   GSI   V+   G+ + E  +   +R+IL GLA+LH  + IHRDIKG N+L+  +  VKL DFG+   L   +    +  G+PYWMAPEV+  D   D  +     +D+WS G T IEM  G PP  +    +A+F +  + PP
Sbjct:   99 DQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYR--SDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPP 251          

HSP 2 Score: 36.1946 bits (82), Expect = 2.574e-27
Identity = 17/41 (41.46%), Postives = 25/41 (60.98%), Query Frame = 3

Query:  462 PHLYQKCYLPRGKDFLRHCLRRNPVERPSACMLLEHPFIRN 584
            P L  K +  +   F+  CL +N ++RPS   LL+HPFIR+
Sbjct:  251 PRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRD 291          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: M4K4_MOUSE (Mitogen-activated protein kinase kinase kinase kinase 4 OS=Mus musculus GN=Map4k4 PE=1 SV=1)

HSP 1 Score: 107.071 bits (266), Expect = 3.351e-27
Identity = 59/155 (38.06%), Postives = 87/155 (56.13%), Query Frame = 2

Query:   11 DHLYIYLEYVHPGSINRYVREHCGD-ITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHL-TGLSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPP 469
            D L++ +E+   GSI   V+   G+ + E  +   +R+IL GLA+LH  + IHRDIKG N+L+  +  VKL DFG+   L   +    +  G+PYWMAPEV+  D   D  +     +D+WS G T IEM  G PP  +    +A+F +  + PP
Sbjct:   98 DQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYR--SDLWSCGITAIEMAEGGPPLCDMHPMRALFLIPRNPPP 250          

HSP 2 Score: 36.1946 bits (82), Expect = 3.351e-27
Identity = 17/41 (41.46%), Postives = 25/41 (60.98%), Query Frame = 3

Query:  462 PHLYQKCYLPRGKDFLRHCLRRNPVERPSACMLLEHPFIRN 584
            P L  K +  +   F+  CL +N ++RPS   LL+HPFIR+
Sbjct:  250 PRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRD 290          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: STK24_HUMAN (Serine/threonine-protein kinase 24 OS=Homo sapiens GN=STK24 PE=1 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 3.403e-27
Identity = 63/155 (40.65%), Postives = 86/155 (55.48%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTGLSYEL-SLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPIPE 478
            L+I +EY+  GS    +    G + E+ +    R+IL GL YLHS   IHRDIK AN+L+   G VKLADFG+   LT    +  +  G+P+WMAPEV++              ADIWSLG T IE+  G+PP SE    + +F +  + PP  E
Sbjct:  107 LWIIMEYLGGGSALDLLEP--GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDS-------KADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE 252          

HSP 2 Score: 33.4982 bits (75), Expect = 3.403e-27
Identity = 17/36 (47.22%), Postives = 23/36 (63.89%), Query Frame = 3

Query:  498 KDFLRHCLRRNPVERPSACMLLEHPFI-RNANYQNY 602
            K+F+  CL + P  RP+A  LL+H FI RNA   +Y
Sbjct:  260 KEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSY 295          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: STK24_MOUSE (Serine/threonine-protein kinase 24 OS=Mus musculus GN=Stk24 PE=1 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 7.509e-27
Identity = 63/155 (40.65%), Postives = 85/155 (54.84%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTGLSYEL-SLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPIPE 478
            L+I +EY+  GS    +    G + E  +    R+IL GL YLHS   IHRDIK AN+L+   G VKLADFG+   LT    +  +  G+P+WMAPEV++              ADIWSLG T IE+  G+PP SE    + +F +  + PP  E
Sbjct:   95 LWIIMEYLGGGSALDLLEP--GPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDS-------KADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLE 240          

HSP 2 Score: 33.4982 bits (75), Expect = 7.509e-27
Identity = 17/36 (47.22%), Postives = 23/36 (63.89%), Query Frame = 3

Query:  498 KDFLRHCLRRNPVERPSACMLLEHPF-IRNANYQNY 602
            K+F+  CL + P  RP+A  LL+H F IRNA   +Y
Sbjct:  248 KEFVEACLNKEPSFRPTAKELLKHKFIIRNAKKTSY 283          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: PAKH_DICDI (Serine/threonine-protein kinase pakH OS=Dictyostelium discoideum GN=pakH-1 PE=3 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 1.269e-26
Identity = 58/150 (38.67%), Postives = 86/150 (57.33%), Query Frame = 2

Query:   20 YIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTGLSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPP 469
            +I ++Y    S N  ++       E  +    +Q L GL YLHS   IHRDIK AN+L+D +G VK+ADFG+ + +     + S+ G+PYWMAPE++    Q D N+++    D+WSLG   IE+  G+PP SE    +AM+ +    PP
Sbjct:  113 WILMDYCSLSSFNDIMQSIGKTFKEKEISLILQQSLLGLVYLHSKQIIHRDIKSANILLDETGQVKIADFGVSQQIQSTFSKGSIAGTPYWMAPEILN---QTDYNNKI----DVWSLGIVAIELADGEPPLSEVNPMRAMYMIGRRPPP 255          

HSP 2 Score: 30.4166 bits (67), Expect = 1.269e-26
Identity = 15/37 (40.54%), Postives = 22/37 (59.46%), Query Frame = 3

Query:  477 KCYLPRGKDFLRHCLRRNPVERPSACMLLEHPFIRNA 587
            K + P    F+  CL ++  ER S   LL+HPFI++A
Sbjct:  261 KKWSPEFVSFVDKCLTKDINERWSPSQLLDHPFIKSA 297          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: TNIK_HUMAN (TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK PE=1 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 1.628e-26
Identity = 56/155 (36.13%), Postives = 85/155 (54.84%), Query Frame = 2

Query:   11 DHLYIYLEYVHPGSINRYVREHCGD-ITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHL-TGLSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPP 469
            D L++ +E+   GS+   ++   G+ + E  +    R+IL GL++LH    IHRDIKG N+L+  +  VKL DFG+   L   +    +  G+PYWMAPEV+  D   D  +     +D+WSLG T IEM  G PP  +    +A+F +  +  P
Sbjct:   99 DQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATY--DFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAP 251          

HSP 2 Score: 36.965 bits (84), Expect = 1.628e-26
Identity = 16/42 (38.10%), Postives = 26/42 (61.90%), Query Frame = 3

Query:  459 APHLYQKCYLPRGKDFLRHCLRRNPVERPSACMLLEHPFIRN 584
            AP L  K +  + + F+  CL +N  +RP+   L++HPFIR+
Sbjct:  250 APRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRD 291          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: TNIK_MOUSE (Traf2 and NCK-interacting protein kinase OS=Mus musculus GN=Tnik PE=1 SV=2)

HSP 1 Score: 103.99 bits (258), Expect = 1.628e-26
Identity = 56/155 (36.13%), Postives = 85/155 (54.84%), Query Frame = 2

Query:   11 DHLYIYLEYVHPGSINRYVREHCGD-ITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHL-TGLSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPP 469
            D L++ +E+   GS+   ++   G+ + E  +    R+IL GL++LH    IHRDIKG N+L+  +  VKL DFG+   L   +    +  G+PYWMAPEV+  D   D  +     +D+WSLG T IEM  G PP  +    +A+F +  +  P
Sbjct:   99 DQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATY--DFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAP 251          

HSP 2 Score: 36.965 bits (84), Expect = 1.628e-26
Identity = 16/42 (38.10%), Postives = 26/42 (61.90%), Query Frame = 3

Query:  459 APHLYQKCYLPRGKDFLRHCLRRNPVERPSACMLLEHPFIRN 584
            AP L  K +  + + F+  CL +N  +RP+   L++HPFIR+
Sbjct:  250 APRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFIRD 291