EY720507

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: KIC1_YEAST (Serine/threonine-protein kinase KIC1 OS=Saccharomyces cerevisiae GN=KIC1 PE=1 SV=1)

HSP 1 Score: 105.916 bits (263), Expect = 2.964e-25
Identity = 59/152 (38.82%), Postives = 83/152 (54.61%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTGLSY-ELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPP 469
            L+I +E+   GS+   +R   G I E  +    R++L  L  +H  N IHRDIK AN+L+   G VKL DFG+   +   S    ++ G+PYWMAPEV+   +  D         DIWSLG T  E+ TG PP+ + E  +AM  ++ S PP
Sbjct:   95 LWIIMEHCAGGSLRSLLRP--GKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTK------VDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPP 238          

HSP 2 Score: 30.8018 bits (68), Expect = 2.964e-25
Identity = 17/40 (42.50%), Postives = 22/40 (55.00%), Query Frame = 3

Query:  462 PHLYQKCYLPRGKDFLRHCLRRNPVERPSACMLLEHPFIR 581
            P L  + Y    K+F+  CL  +P ER SA  LL+  FIR
Sbjct:  238 PRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFIR 277          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: M4K3_MOUSE (Mitogen-activated protein kinase kinase kinase kinase 3 OS=Mus musculus GN=Map4k3 PE=2 SV=3)

HSP 1 Score: 105.145 bits (261), Expect = 2.972e-25
Identity = 60/160 (37.50%), Postives = 94/160 (58.75%), Query Frame = 2

Query:    5 RPDHLYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTG-LSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPIPEM 481
            R D L+I +E+   GS+   +    G ++E  +   +R+ L GL YLHS   +HRDIKGAN+L+  +G VKLADFG+   +T  ++   S  G+PYWMAPEV  A +++ G +    L D+W++G T IE+   +PP  +    +A+F +  S    P++
Sbjct:   82 RRDKLWICMEFCGGGSLQD-IYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEV--AAVERKGGYN--QLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKL 236          

HSP 2 Score: 31.5722 bits (70), Expect = 2.972e-25
Identity = 12/25 (48.00%), Postives = 19/25 (76.00%), Query Frame = 3

Query:  504 FLRHCLRRNPVERPSACMLLEHPFI 578
            F++  L +NP +RP+A  LL+HPF+
Sbjct:  249 FVKMALTKNPKKRPNAEKLLQHPFV 273          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: M4K3_HUMAN (Mitogen-activated protein kinase kinase kinase kinase 3 OS=Homo sapiens GN=MAP4K3 PE=1 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 2.972e-25
Identity = 60/160 (37.50%), Postives = 94/160 (58.75%), Query Frame = 2

Query:    5 RPDHLYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTG-LSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPIPEM 481
            R D L+I +E+   GS+   +    G ++E  +   +R+ L GL YLHS   +HRDIKGAN+L+  +G VKLADFG+   +T  ++   S  G+PYWMAPEV  A +++ G +    L D+W++G T IE+   +PP  +    +A+F +  S    P++
Sbjct:   82 RRDKLWICMEFCGGGSLQD-IYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEV--AAVERKGGYN--QLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKL 236          

HSP 2 Score: 31.5722 bits (70), Expect = 2.972e-25
Identity = 12/25 (48.00%), Postives = 19/25 (76.00%), Query Frame = 3

Query:  504 FLRHCLRRNPVERPSACMLLEHPFI 578
            F++  L +NP +RP+A  LL+HPF+
Sbjct:  249 FVKMALTKNPKKRPTAEKLLQHPFV 273          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: M4K3_RAT (Mitogen-activated protein kinase kinase kinase kinase 3 OS=Rattus norvegicus GN=Map4k3 PE=1 SV=2)

HSP 1 Score: 105.145 bits (261), Expect = 2.973e-25
Identity = 60/160 (37.50%), Postives = 94/160 (58.75%), Query Frame = 2

Query:    5 RPDHLYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTG-LSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPIPEM 481
            R D L+I +E+   GS+   +    G ++E  +   +R+ L GL YLHS   +HRDIKGAN+L+  +G VKLADFG+   +T  ++   S  G+PYWMAPEV  A +++ G +    L D+W++G T IE+   +PP  +    +A+F +  S    P++
Sbjct:   82 RRDKLWICMEFCGGGSLQD-IYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEV--AAVERKGGYN--QLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKL 236          

HSP 2 Score: 31.5722 bits (70), Expect = 2.973e-25
Identity = 12/25 (48.00%), Postives = 19/25 (76.00%), Query Frame = 3

Query:  504 FLRHCLRRNPVERPSACMLLEHPFI 578
            F++  L +NP +RP+A  LL+HPF+
Sbjct:  249 FVKMALTKNPKKRPTAEKLLQHPFV 273          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: DST4_DICDI (Serine/threonine-protein kinase dst4 OS=Dictyostelium discoideum GN=dst4 PE=3 SV=1)

HSP 1 Score: 102.449 bits (254), Expect = 3.002e-25
Identity = 58/150 (38.67%), Postives = 83/150 (55.33%), Query Frame = 2

Query:    5 RPDHLYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTGLSY-ELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKV 451
            + ++L I +EY   GSI   ++     +TE+ +     QI+ GL YLHS   +HRDIK  N+LV+  G  KLADFG+   L    + + ++ GSPYWM+PEV+       G++     ADIWSLG T IEM   KPP       + +F +
Sbjct:   87 KENNLMIVMEYCDGGSILDIMQMCSITLTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLGQAKLADFGVSAILVNTGFKQKTVVGSPYWMSPEVIS---PPKGSNGYDSKADIWSLGITAIEMAESKPPLFNLNPVKVIFVI 233          

HSP 2 Score: 34.2686 bits (77), Expect = 3.002e-25
Identity = 15/31 (48.39%), Postives = 19/31 (61.29%), Query Frame = 3

Query:  489 PRGKDFLRHCLRRNPVERPSACMLLEHPFIR 581
            P   DF+  CL +   +RPSA  LL HPFI+
Sbjct:  249 PEFNDFISVCLNKEADKRPSAVDLLNHPFIK 279          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: PAKA_DICDI (Serine/threonine-protein kinase pakA OS=Dictyostelium discoideum GN=pakA PE=1 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 5.012e-25
Identity = 59/157 (37.58%), Postives = 91/157 (57.96%), Query Frame = 2

Query:   11 DHLYIYLEYVHPGSINRYVREHCG-DITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTGLSYEL-SLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKV-LNSTPPI 472
            D L++ +E++  G +   + ++    + ES +    +++L GL Y+H  N IHRDIK  N+L+ A+G +KLADFG    LT +  E  S+ G+PYWMAPE+++      GN+      D+WSLG    EM  G+PP+ EF   +A+F +     PPI
Sbjct:  978 DELWVAMEFMSGGCLTEVLDQYRDIQLNESQIAFVCQEVLRGLEYIHKFNRIHRDIKSDNILIGANGEIKLADFGYAAQLTQIRQERNSVVGTPYWMAPELIR------GNN-YDFKVDVWSLGIMTREMAEGEPPYLEFPPLRALFLLTTQGLPPI 1127          

HSP 2 Score: 31.5722 bits (70), Expect = 5.012e-25
Identity = 13/29 (44.83%), Postives = 19/29 (65.52%), Query Frame = 3

Query:  501 DFLRHCLRRNPVERPSACMLLEHPFIRNA 587
            DFL  CL ++  +R S+  LL HPF++ A
Sbjct: 1139 DFLALCLEKDTEKRASSSSLLHHPFLKRA 1167          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: STK4_XENLA (Serine/threonine-protein kinase 4 OS=Xenopus laevis GN=stk4 PE=2 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 8.032e-25
Identity = 65/163 (39.88%), Postives = 94/163 (57.67%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTG-LSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPI---PEMLSSE 493
            L+I +E+   GS++  +R     + E  +    +  L GL YLH    IHRDIK  N+L+   G  KLADFG+   LT  ++   ++ G+P+WMAPEV    IQ+ G + V   ADIWSLG T IEM  GKPP++E    +A+F + ++ PP    PE+ S +
Sbjct:   98 LWIVMEFCGGGSVSDIIRLRKQTLNEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLSCEGTAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEV----IQEIGYNCV---ADIWSLGITAIEMAEGKPPYAEIHPMRAIFMIPSNPPPTFRKPELWSKD 253          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: STK4_XENTR (Serine/threonine-protein kinase 4 OS=Xenopus tropicalis GN=stk4 PE=2 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 1.049e-24
Identity = 66/163 (40.49%), Postives = 95/163 (58.28%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTG-LSYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPPI---PEMLSSE 493
            L+I +E+   GSI+  +R     + E       +  L GL YLH    IHRDIK  N+L+++ G  KLADFG+   LT  ++   ++ G+P+WMAPEV    IQ+ G + V   ADIWSLG T IEM  GKPP++E    +A+F + ++ PP    PE+ S +
Sbjct:   98 LWIVMEFCGGGSISDIIRLRKQTLKEDETATILQSTLKGLEYLHFMRKIHRDIKAGNILLNSEGTAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEV----IQEIGYNCV---ADIWSLGITAIEMAEGKPPYAEIHPMRAIFMIPSNPPPTFRKPELWSKD 253          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: PPK11_SCHPO (Serine/threonine-protein kinase ppk11 OS=Schizosaccharomyces pombe GN=ppk11 PE=2 SV=1)

HSP 1 Score: 103.219 bits (256), Expect = 1.471e-24
Identity = 59/152 (38.82%), Postives = 84/152 (55.26%), Query Frame = 2

Query:   17 LYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLTGL-SYELSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQAMFKVLNSTPP 469
            L+I +EY   GS    ++   G  +E ++    RQ+L  L YLH    +HRDIK AN+L    G+VKLADFG+   L  L        G+P+WMAPEV++   Q   N++    ADIWSLG T  E+ TG+PP+S     + +  +   +PP
Sbjct:   77 LWITMEYCDGGSCLDLLKLS-GTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMKDGLVKLADFGVSGQLESLRDKNDDFVGTPFWMAPEVVK---QTGYNYK----ADIWSLGITAYELATGEPPYSGIHPMKVLLLIPKHSPP 220          

HSP 2 Score: 31.187 bits (69), Expect = 1.471e-24
Identity = 12/27 (44.44%), Postives = 20/27 (74.07%), Query Frame = 3

Query:  501 DFLRHCLRRNPVERPSACMLLEHPFIR 581
            DF+ +CL++NP +R +A  L +H FI+
Sbjct:  233 DFVSNCLKKNPKDRATAEYLSKHKFIK 259          

BLAST of EY720507 vs. ExPASy Swiss-Prot
Match: WIS4_SCHPO (MAP kinase kinase kinase wis4 OS=Schizosaccharomyces pombe GN=wis4 PE=2 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 1.866e-24
Identity = 65/180 (36.11%), Postives = 100/180 (55.56%), Query Frame = 2

Query:   11 DHLYIYLEYVHPGSINRYVREHCGDITESIVCNFTRQILNGLAYLHSTNTIHRDIKGANLLVDASGVVKLADFGIGKHLT-----GLSYE------LSLKGSPYWMAPEVMQADIQKDGNHRVALLADIWSLGCTVIEMLTGKPPWSEFEGPQA-MFKV-LNSTPPIP--EMLSSEGEGF 505
            + +YI++E+   GS+   +  H     E+++  +  Q+L GLAY+HS + +HRDIK AN+L+D  G++K +DFG   +++      + YE        L G+P +MAPE++    + D         DIWSLGC ++EM+TG  PWSE +   A M+ V    TP IP  E +SS    F
Sbjct: 1109 EKVYIFMEFCQGGSLADLLA-HGRIEDENVLKVYVVQLLEGLAYIHSQHILHRDIKPANILLDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPMYMAPEIILGTKKGDFG-----AMDIWSLGCVILEMMTGSTPWSEMDNEWAIMYHVAAMHTPSIPQNEKISSLARDF 1282          

HSP 2 Score: 33.8834 bits (76), Expect = 1.866e-24
Identity = 13/27 (48.15%), Postives = 18/27 (66.67%), Query Frame = 3

Query:  498 KDFLRHCLRRNPVERPSACMLLEHPFI 578
            +DF+  C  R+P +RP A  LL HP+I
Sbjct: 1280 RDFIEQCFERDPEQRPRAVDLLTHPWI 1306