EY693108

BLAST of EY693108 vs. ExPASy Swiss-Prot
Match: CUL1_DICDI (Cullin-1 OS=Dictyostelium discoideum GN=culA PE=1 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 6.239e-22
Identity = 61/194 (31.44%), Postives = 105/194 (54.12%), Query Frame = 3

Query:   30 FHYLDRYFIARRSLPPLNEV------GLTCFRDLVYTELNGKVRDAVITLIDQEREGEQIDRALLKNVLDIFVEIGMGQ-------MDYYENDFETAMLKDTAAYYSRKASNWILEDSCPDYMLKAEECLKREKDRVSHYLHSSSEPKLLEKVQHELLSVYANQLLEKEHSXCHALLRDDKVEDLSRMFRLFSK 572
            F Y++RY+I R       EV       L  +RD ++T L  ++ ++++ +I+ ER G QI+  L+K V++ +V +G+ +       +  Y++ FE   L  T  YY+ +++ +I E+S  DYM K E  L  E  RV  YLH ++E +L+ K +  L+  +    +E   +    LL  DK+ DL+RM+ L S+
Sbjct:  130 FQYMNRYWIKREIDDGKKEVYEIFILSLVIWRDCLFTPLKQRLTNSLLDIIESERNGYQINTHLIKGVINGYVSLGLNREKPKETILQVYKSGFEELFLTATENYYTNESAKFISENSVADYMKKVETRLNEEVKRVQQYLHQNTESELIAKCEKVLIEKH----VEVIWNEFQTLLEKDKIPDLTRMYSLLSR 319          

HSP 2 Score: 23.483 bits (49), Expect = 6.239e-22
Identity = 9/15 (60.00%), Postives = 13/15 (86.67%), Query Frame = 2

Query:  563 LFKIPRGLDPVSTSL 607
            L +IPRGL+P+ T+L
Sbjct:  317 LSRIPRGLEPLRTTL 331          

BLAST of EY693108 vs. ExPASy Swiss-Prot
Match: CUL3_CAEEL (Cullin-3 OS=Caenorhabditis elegans GN=cul-3 PE=1 SV=2)

HSP 1 Score: 99.7525 bits (247), Expect = 2.416e-20
Identity = 52/184 (28.26%), Postives = 104/184 (56.52%), Query Frame = 3

Query:   36 YLDRYFIARRS-LPPLNEVGLTCFRDLVYTE--LNGKVRDAVITLIDQEREGEQIDRALLKNVLDIFVEIGMGQMDYYENDFETAMLKDTAAYYSRKASNWIL--EDSCPDYMLKAEECLKREKDRVSHYLHSSSEPKLLEKVQHELLSVYANQLLEKEHSXCHALLRDDKVEDLSRMFRLFSK 572
            Y+DR ++A+ + + P+  +GL  +R  +  +  +  ++RDA++ LI  +R+  QI+   +KN  D+ + +G+     YE++FE  +LK+T+ YY     NW+    D+C  Y+ + E  +  E  R S YL   +E K+L+ +   +++ +   ++  ++     +L   K+EDL+R+FR+F +
Sbjct:  122 YMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDAC-FYLAQVEIAMHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKR 304          

BLAST of EY693108 vs. ExPASy Swiss-Prot
Match: CUL4A_HUMAN (Cullin-4A OS=Homo sapiens GN=CUL4A PE=1 SV=3)

HSP 1 Score: 98.9821 bits (245), Expect = 4.121e-20
Identity = 62/208 (29.81%), Postives = 117/208 (56.25%), Query Frame = 3

Query:   30 FHYLDRYFIARRS-LPPLNEVGLTCFRDLVYTE--LNGKVRDAVITLIDQEREGEQIDRALLKNVLDIFVEIGMGQMDYYENDFETAMLKDTAAYYSRKASNWILEDSCPDYMLKAEECLKREKDRVSHYLHSSSEPKLLEKVQHELLSVYANQLLEKEHSXCHALLRDDKVEDLSRMFRLFSKYLEA-*ILFRHL*QHVTAEGTALV 641
            F +LDR ++ + S LP + ++GL  FR  + ++  +  K  D ++ LI++ER GE +DR+LL+++L +     +  +  Y++ FE   L++T   Y+ +    + E   P+Y+    + L+ E DRV  YL  S++  L+  V+ +LL  +   +L+K       LL +++V DL++M++LFS+       L +H  +++   GTA+V
Sbjct:  153 FLFLDRTYVLQNSTLPSIWDMGLELFRTHIISDKMVQSKTIDGILLLIERERSGEAVDRSLLRSLLGM-----LSDLQVYKDSFELKFLEETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLDHSTQKPLIACVEKQLLGEHLTAILQK---GLDHLLDENRVPDLAQMYQLFSRVRGGQQALLQHWSEYIKTFGTAIV 352          

BLAST of EY693108 vs. ExPASy Swiss-Prot
Match: CUL4A_MOUSE (Cullin-4A OS=Mus musculus GN=Cul4a PE=2 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 9.181e-20
Identity = 62/210 (29.52%), Postives = 118/210 (56.19%), Query Frame = 3

Query:   30 FHYLDRYFIARRS-LPPLNEVGLTCFRDLVYTE--LNGKVRDAVITLIDQEREGEQIDRALLKNVLDIFVEIGMGQMDYYENDFETAMLKDTAAYYSRKASNWILEDSCPDYMLKAEECLKREKDRVSHYLHSSSEPKLLEKVQHELLSVYANQLLEK--EHSXCHALLRDDKVEDLSRMFRLFSKYLEA-*ILFRHL*QHVTAEGTALV 641
            F +LDR ++ + S LP + ++GL  FR+ + ++  +  K  D ++ LI +ER GE +DR+LL+++L +     +  +  Y++ FE   L++T   Y+ +    + +   P+Y+    + L+ E DRV  YL  S++  L+  V+ +LL  +   +L+K  EH     LL +++V DL++M++LFS+       L +H  +++   GT +V
Sbjct:  153 FLFLDRTYVLQNSMLPSIWDMGLELFRNHIISDRMVQSKTIDGILLLIGRERSGEAVDRSLLRSLLSM-----LSDLQVYKDSFELKFLEETNCLYAAEGQRLMQDREVPEYLNHVSKRLEEEADRVITYLDHSTQKPLIACVEKQLLGEHLTAILQKGLEH-----LLDENRVPDLTQMYQLFSRVKGGQHALLQHWSEYIKTFGTTIV 352          

BLAST of EY693108 vs. ExPASy Swiss-Prot
Match: CUL4B_HUMAN (Cullin-4B OS=Homo sapiens GN=CUL4B PE=1 SV=3)

HSP 1 Score: 96.2857 bits (238), Expect = 2.671e-19
Identity = 58/208 (27.88%), Postives = 118/208 (56.73%), Query Frame = 3

Query:   30 FHYLDRYFIARRS-LPPLNEVGLTCFRDLVYTE--LNGKVRDAVITLIDQEREGEQIDRALLKNVLDIFVEIGMGQMDYYENDFETAMLKDTAAYYSRKASNWILEDSCPDYMLKAEECLKREKDRVSHYLHSSSEPKLLEKVQHELLSVYANQLLEKEHSXCHALLRDDKVEDLSRMFRLFSKYL-EA*ILFRHL*QHVTAEGTALV 641
            F +LDR ++ + S LP + ++GL  FR  + ++  +  K  D ++ LI++ER GE IDR+LL+++L +     +  +  Y++ FE   L++T   Y+ +    + E   P+Y+    + L+ E DR+  YL  +++  L+  V+ +LL  +   +L+K     + LL +++++DLS +++LFS+      +L +   +++ A G+ +V
Sbjct:  289 FLFLDRTYVLQNSMLPSIWDMGLELFRAHIISDQKVQNKTIDGILLLIERERNGEAIDRSLLRSLLSM-----LSDLQIYQDSFEQRFLEETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILQK---GLNNLLDENRIQDLSLLYQLFSRVRGGVQVLLQQWIEYIKAFGSTIV 488          

BLAST of EY693108 vs. ExPASy Swiss-Prot
Match: CUL2_PONAB (Cullin-2 OS=Pongo abelii GN=CUL2 PE=2 SV=1)

HSP 1 Score: 82.0333 bits (201), Expect = 5.213e-15
Identity = 55/200 (27.50%), Postives = 98/200 (49.00%), Query Frame = 3

Query:   30 FHYLDRYFIARRSLP---------------PLNEVG---LTCFRDLVYTELNGKVRDAVITLIDQEREGEQIDRALLKNVLDIFVEIGMGQ----MDYYENDFETAMLKDTAAYYSRKASNWILEDSCPDYMLKAEECLKREKDRVSHYLHSSSEPKLLEKVQHELLSVYANQLLEKEHSXCHALLRDDKVEDLSRMFRL 563
            + YL+  FI +  L                PL E+G   L  +R L+   L   +   ++  I  +R GE  ++ ++  V++ FV +   +    + +Y+  FE+  L +T  YY ++ASN + E +C  YM K    LK E+ R   YLH SS  K++ + Q  +++ +    L+  H+ CH ++R +K  D++ M+ L
Sbjct:  105 YRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEIRCRKYLHPSSYTKVIHECQQRMVADH----LQFLHAECHNIIRQEKKNDMANMYVL 300          

BLAST of EY693108 vs. ExPASy Swiss-Prot
Match: CUL2_HUMAN (Cullin-2 OS=Homo sapiens GN=CUL2 PE=1 SV=2)

HSP 1 Score: 82.0333 bits (201), Expect = 5.213e-15
Identity = 55/200 (27.50%), Postives = 98/200 (49.00%), Query Frame = 3

Query:   30 FHYLDRYFIARRSLP---------------PLNEVG---LTCFRDLVYTELNGKVRDAVITLIDQEREGEQIDRALLKNVLDIFVEIGMGQ----MDYYENDFETAMLKDTAAYYSRKASNWILEDSCPDYMLKAEECLKREKDRVSHYLHSSSEPKLLEKVQHELLSVYANQLLEKEHSXCHALLRDDKVEDLSRMFRL 563
            + YL+  FI +  L                PL E+G   L  +R L+   L   +   ++  I  +R GE  ++ ++  V++ FV +   +    + +Y+  FE+  L +T  YY ++ASN + E +C  YM K    LK E+ R   YLH SS  K++ + Q  +++ +    L+  H+ CH ++R +K  D++ M+ L
Sbjct:  105 YRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEIRCRKYLHPSSYTKVIHECQQRMVADH----LQFLHAECHNIIRQEKKNDMANMYVL 300          

BLAST of EY693108 vs. ExPASy Swiss-Prot
Match: CUL1_CAEEL (Cullin-1 OS=Caenorhabditis elegans GN=cul-1 PE=1 SV=1)

HSP 1 Score: 81.2629 bits (199), Expect = 8.892e-15
Identity = 72/235 (30.64%), Postives = 119/235 (50.64%), Query Frame = 3

Query:   30 FHYLDRYFIARRSLPPLNE-------VGLTCFRDLVYTELNGKVRDAVITLIDQEREGEQIDRALLKNVLDIFVEIGMGQMD-------------YYENDFETAMLKDTAAYYSRKASNWILED-SCPDYMLKAEECLKREKDRVSHYLHSSSEPKLLEKVQHELLSVYANQL--LEKEHSXCHALLRDDKVEDLSRMFRLFSKYLEA-*ILFRHL*QHVTAEG-TALVKLAEDA 659
            F YL+R++I RR L   +E       + L  ++  ++ +L  KV DA++ LI  ER G  I+   +  V++  VE+G+   +              Y+  FE   L+ T  +Y+++A+N++    +  DYM+K E  L +E DR   YL+SS++  L    +  L+S   NQL  L++       LL D + +DLSRMF+L  +       L + L  H+  EG  AL ++A +A
Sbjct:  133 FAYLNRHWI-RRELDEGHENIYMVYTLALVVWKRNLFNDLKDKVIDAMLELIRSERTGSMINSRYISGVVECLVELGVDDSETDAKKDAETKKLAVYKEFFEVKFLEATRGFYTQEAANFLSNGGNVTDYMIKVETRLNQEDDRCQLYLNSSTKTPLATCCESVLIS---NQLDFLQRHFG---GLLVDKRDDDLSRMFKLCDRVPNGLDELRKSLENHIAKEGHQALERVAMEA 360          

BLAST of EY693108 vs. ExPASy Swiss-Prot
Match: CUL2_MOUSE (Cullin-2 OS=Mus musculus GN=Cul2 PE=1 SV=2)

HSP 1 Score: 78.5666 bits (192), Expect = 5.764e-14
Identity = 48/170 (28.24%), Postives = 90/170 (52.94%), Query Frame = 3

Query:   75 PLNEVG---LTCFRDLVYTELNGKVRDAVITLIDQEREGEQIDRALLKNVLDIFVEIGMGQ----MDYYENDFETAMLKDTAAYYSRKASNWILEDSCPDYMLKAEECLKREKDRVSHYLHSSSEPKLLEKVQHELLSVYANQLLEKEHSXCHALLRDDKVEDLSRMFRL 563
            PL E+G   L  +R L+   L   +   ++  I  +R GE  ++ ++  V++ FV +   +    + +Y+  F +  L +T  YY ++ASN + E +C  YM K    LK E+ R   YLH SS  K++ + Q  +++ +    L+  HS CH++++ ++  D++ M+ L
Sbjct:  135 PLMEIGELALDMWRKLMVEPLQNILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQGIFVSPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEIRCRKYLHPSSYTKVIHECQQRMVADH----LQFLHSECHSIIQQERKNDMANMYVL 300          

BLAST of EY693108 vs. ExPASy Swiss-Prot
Match: CUL1_DROME (Cullin homolog 1 OS=Drosophila melanogaster GN=lin19 PE=1 SV=2)

HSP 1 Score: 78.1814 bits (191), Expect = 7.528e-14
Identity = 50/196 (25.51%), Postives = 99/196 (50.51%), Query Frame = 3

Query:   33 HYLDRYFIAR------RSLPPLNEVGLTCFRDLVYTELNGKVRDAVITLIDQEREGEQIDRALLKNVLDIFVEIGMGQMD---------YYENDFETAMLKDTAAYYSRKASNWILEDSCPDYMLKAEECLKREKDRVSHYLHSSSEPKLLEKVQHELLSVYANQLLEKE----HSXCHALLRDDKVEDLSRMFRL 563
            +YL+R ++ R      + +  +  + L  ++  ++  LN  V  AV+  I++ER+G+ I+R+L+++V++ +VE+   + D          Y+ +FE   + DT+A+Y +++  ++  ++  +Y+   E  L+ E  RV  +   +    L E     L S     L+EK     H+    LL  D+ +DL RM+ L
Sbjct:  129 NYLNRNWVKRECEEGQKGIYKIYRLALVAWKGHLFQVLNEPVTKAVLKSIEEERQGKLINRSLVRDVIECYVELSFNEEDTDAEQQKLSVYKQNFENKFIADTSAFYEKESDAFLSTNTVTEYLKHVENRLEEETQRVRGFNSKNGLSYLHETTADVLKSTCEEVLIEKHLKIFHTEFQNLLNADRNDDLKRMYSL 324