EY692991

BLAST of EY692991 vs. ExPASy Swiss-Prot
Match: STK6_PIG (Serine/threonine-protein kinase 6 OS=Sus scrofa GN=AURKA PE=3 SV=1)

HSP 1 Score: 197.208 bits (500), Expect = 1.158e-49
Identity = 95/148 (64.19%), Postives = 116/148 (78.38%), Query Frame = 3

Query:   27 SKYPVALKIIFKEQIEKYKIQHQLRREMEIQSSLRHPNILRLYGWFHDDERIFLILEYAHRGELYRELRKHRRFTEQQAATYIASLTNALAYCHENHVIHRDIKPENLLLDHEGRLKIGDSGWSVQS-RSKRHTMCGTLHYLAPEMVD 467
            SK+ +ALK++FK Q+EK  ++HQLRRE+EIQS LRHPNILRLYG+FHD  R++LILEYA  G +YREL+K  +F EQ+ ATYI  L NAL+YCH   VIHRDIKPENLLL   G LKI D GWSV +  S+R T+CGTL YL PEM++
Sbjct:  155 SKFILALKVLFKTQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIE 302          

BLAST of EY692991 vs. ExPASy Swiss-Prot
Match: STK6_HUMAN (Serine/threonine-protein kinase 6 OS=Homo sapiens GN=AURKA PE=1 SV=2)

HSP 1 Score: 197.208 bits (500), Expect = 1.158e-49
Identity = 95/148 (64.19%), Postives = 116/148 (78.38%), Query Frame = 3

Query:   27 SKYPVALKIIFKEQIEKYKIQHQLRREMEIQSSLRHPNILRLYGWFHDDERIFLILEYAHRGELYRELRKHRRFTEQQAATYIASLTNALAYCHENHVIHRDIKPENLLLDHEGRLKIGDSGWSVQS-RSKRHTMCGTLHYLAPEMVD 467
            SK+ +ALK++FK Q+EK  ++HQLRRE+EIQS LRHPNILRLYG+FHD  R++LILEYA  G +YREL+K  +F EQ+ ATYI  L NAL+YCH   VIHRDIKPENLLL   G LKI D GWSV +  S+R T+CGTL YL PEM++
Sbjct:  155 SKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIE 302          

BLAST of EY692991 vs. ExPASy Swiss-Prot
Match: STK6_BOVIN (Serine/threonine-protein kinase 6 OS=Bos taurus GN=AURKA PE=2 SV=1)

HSP 1 Score: 197.208 bits (500), Expect = 1.158e-49
Identity = 95/148 (64.19%), Postives = 116/148 (78.38%), Query Frame = 3

Query:   27 SKYPVALKIIFKEQIEKYKIQHQLRREMEIQSSLRHPNILRLYGWFHDDERIFLILEYAHRGELYRELRKHRRFTEQQAATYIASLTNALAYCHENHVIHRDIKPENLLLDHEGRLKIGDSGWSVQS-RSKRHTMCGTLHYLAPEMVD 467
            SK+ +ALK++FK Q+EK  ++HQLRRE+EIQS LRHPNILRLYG+FHD  R++LILEYA  G +YREL+K  +F EQ+ ATYI  L NAL+YCH   VIHRDIKPENLLL   G LKI D GWSV +  S+R T+CGTL YL PEM++
Sbjct:  155 SKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIE 302          

BLAST of EY692991 vs. ExPASy Swiss-Prot
Match: STK6_XENLA (Serine/threonine-protein kinase 6 OS=Xenopus laevis GN=aurka PE=2 SV=1)

HSP 1 Score: 193.356 bits (490), Expect = 1.673e-48
Identity = 93/148 (62.84%), Postives = 115/148 (77.70%), Query Frame = 3

Query:   27 SKYPVALKIIFKEQIEKYKIQHQLRREMEIQSSLRHPNILRLYGWFHDDERIFLILEYAHRGELYRELRKHRRFTEQQAATYIASLTNALAYCHENHVIHRDIKPENLLLDHEGRLKIGDSGWSVQS-RSKRHTMCGTLHYLAPEMVD 467
            SK+ +ALK++FK Q+EK  ++HQLRRE+EIQS LRHPNILRLYG+FHD  R++LIL+YA  GEL+REL+K  RF +Q++A YI  L  AL YCH   VIHRDIKPENLLL   G LKI D GWSV +  S+R T+CGTL YL PEM++
Sbjct:  162 SKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEALLYCHSKKVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIE 309          

BLAST of EY692991 vs. ExPASy Swiss-Prot
Match: STK6L_XENLA (Serine/threonine-protein kinase Eg2-like OS=Xenopus laevis PE=2 SV=2)

HSP 1 Score: 193.356 bits (490), Expect = 1.673e-48
Identity = 93/148 (62.84%), Postives = 115/148 (77.70%), Query Frame = 3

Query:   27 SKYPVALKIIFKEQIEKYKIQHQLRREMEIQSSLRHPNILRLYGWFHDDERIFLILEYAHRGELYRELRKHRRFTEQQAATYIASLTNALAYCHENHVIHRDIKPENLLLDHEGRLKIGDSGWSVQS-RSKRHTMCGTLHYLAPEMVD 467
            SK+ +ALK++FK Q+EK  ++HQLRRE+EIQS LRHPNILRLYG+FHD  R++LIL+YA  GEL+REL+K  RF +Q++A YI  L  AL YCH   VIHRDIKPENLLL   G LKI D GWSV +  S+R T+CGTL YL PEM++
Sbjct:  162 SKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSALYIKQLAEALLYCHSKKVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIE 309          

BLAST of EY692991 vs. ExPASy Swiss-Prot
Match: IPL1_ASHGO (Spindle assembly checkpoint kinase OS=Ashbya gossypii GN=IPL1 PE=3 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 3.014e-47
Identity = 70/151 (46.36%), Postives = 107/151 (70.86%), Query Frame = 3

Query:   27 SKYPVALKIIFKEQIEKYKIQHQLRREMEIQSSLRHPNILRLYGWFHDDERIFLILEYAHRGELYRELRKHRRFTEQQAATYIASLTNALAYCHENHVIHRDIKPENLLLDHEGRLKIGDSGWSV--QSRSKRHTMCGTLHYLAPEMVDTK 473
            S +  ALK + K+ I +Y I+ Q RRE+EIQSSLRHPN+ +LYG+FHD++R++L++EY   GELY+ L+    F +  A+ Y+  + +AL Y HE +++HRDIKPEN+++     +K+ D GWSV     SKR T+CGT+ YL+PE++ ++
Sbjct:  131 SGFVCALKAMEKKDIIQYNIEKQFRREVEIQSSLRHPNLTQLYGYFHDEKRVYLLMEYLVNGELYKHLKGRSHFNDVVASYYVYQMADALDYMHERNILHRDIKPENIIIGFNNTIKLTDFGWSVITPKGSKRKTLCGTVDYLSPELIRSR 281          

HSP 2 Score: 45.0542 bits (105), Expect = 3.014e-47
Identity = 19/37 (51.35%), Postives = 27/37 (72.97%), Query Frame = 2

Query:  470 KEHDYAVDNWTLGILCYELLYGAPPFEAESQKTRSRR 580
            +E++  VD W LG+L YELL G+PPFE ES++   +R
Sbjct:  281 REYNEKVDVWALGVLTYELLVGSPPFEEESKELTYKR 317          

HSP 3 Score: 31.187 bits (69), Expect = 3.014e-47
Identity = 19/48 (39.58%), Postives = 29/48 (60.42%), Query Frame = 1

Query:  556 ESKD-TFXKIMKVDLSFPSAPSISAEDIHLISRLLVKDSSQTLSLQKI 696
            ESK+ T+ +I+K +L FP    +  E  HLISRLL  D    + L+++
Sbjct:  309 ESKELTYKRILKRNLIFPD--HVDTEARHLISRLLEYDPGDRIPLKEV 354          

BLAST of EY692991 vs. ExPASy Swiss-Prot
Match: AURKB_DROME (Serine/threonine-protein kinase Ial OS=Drosophila melanogaster GN=ial PE=1 SV=1)

HSP 1 Score: 166.007 bits (419), Expect = 5.335e-47
Identity = 82/150 (54.67%), Postives = 107/150 (71.33%), Query Frame = 3

Query:   27 SKYPVALKIIFKEQIEKYKIQHQLRREMEIQSSLRHPNILRLYGWFHDDERIFLILEYAHRGELYRELR--KHRRFTEQQAATYIASLTNALAYCHENHVIHRDIKPENLLLDHEGRLKIGDSGWSVQS-RSKRHTMCGTLHYLAPEMVD 467
            S Y VA+K++FKE++ K  +Q Q+ RE+EIQS L+HP+ILRL  WFHD+ RI+L LE A  GEL++ LR   + RF E ++A Y   + NAL YCH N+VIHRD+KPEN+LL     LK+ D GWS  +  +KR T+CGTL YL PEMVD
Sbjct:   75 SHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHPHILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKRRTLCGTLDYLPPEMVD 224          

HSP 2 Score: 43.8986 bits (102), Expect = 5.335e-47
Identity = 17/31 (54.84%), Postives = 23/31 (74.19%), Query Frame = 2

Query:  476 HDYAVDNWTLGILCYELLYGAPPFEAESQKT 568
            +D +VD W LGILCYE + G PPFE+ S ++
Sbjct:  228 YDDSVDQWCLGILCYEFVVGCPPFESNSTES 258          

BLAST of EY692991 vs. ExPASy Swiss-Prot
Match: IPL1_YEAST (Spindle assembly checkpoint kinase OS=Saccharomyces cerevisiae GN=IPL1 PE=1 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 2.003e-46
Identity = 72/149 (48.32%), Postives = 108/149 (72.48%), Query Frame = 3

Query:   33 YPVALKIIFKEQIEKYKIQHQLRREMEIQSSLRHPNILRLYGWFHDDERIFLILEYAHRGELYRELRKHRRFTEQQAATYIASLTNALAYCHENHVIHRDIKPENLLLDHEGRLKIGDSGWSV--QSRSKRHTMCGTLHYLAPEMVDTK 473
            Y  ALK++ KE+I KY +Q Q RRE+EIQ+SL HPN+ + YG+FHD++R++L++EY   GE+Y+ LR H  F +  A+ YI  + NAL Y H+ ++IHRDIKPEN+L+     +K+ D GWS+     ++R T+CGT+ YL+PEMV+++
Sbjct:  128 YICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESR 276          

HSP 2 Score: 48.1358 bits (113), Expect = 2.003e-46
Identity = 19/37 (51.35%), Postives = 27/37 (72.97%), Query Frame = 2

Query:  470 KEHDYAVDNWTLGILCYELLYGAPPFEAESQKTRSRR 580
            +E+D+ +D W LG+L +ELL GAPPFE E + T  +R
Sbjct:  276 REYDHTIDAWALGVLAFELLTGAPPFEEEMKDTTYKR 312          

BLAST of EY692991 vs. ExPASy Swiss-Prot
Match: IPL1_CANGA (Spindle assembly checkpoint kinase OS=Candida glabrata GN=IPL1 PE=3 SV=1)

HSP 1 Score: 142.124 bits (357), Expect = 2.634e-45
Identity = 64/148 (43.24%), Postives = 103/148 (69.59%), Query Frame = 3

Query:   27 SKYPVALKIIFKEQIEKYKIQHQLRREMEIQSSLRHPNILRLYGWFHDDERIFLILEYAHRGELYRELRKHRRFTEQQAATYIASLTNALAYCHENHVIHRDIKPENLLLDHEGRLKIGDSGWSV--QSRSKRHTMCGTLHYLAPEMV 464
            S +  ALK I K +I ++ +  QL+RE++IQ  + HPNI++LY  FHD++R++L++E++  GELY+ L+ +  F +  A+ YI  + +AL Y H+  +IHRD+KPEN+L+  +  +K+ D GWS+     SKR T+CGT+ YL+PEM+
Sbjct:  122 SGFICALKAIEKNEILQFNLLKQLKREVDIQLGMDHPNIIKLYAHFHDEKRVYLLMEHSINGELYKSLKNNGPFNDVLASHYIYQIADALHYMHKKRIIHRDVKPENVLIGFDNVVKLADFGWSILNPEGSKRKTLCGTIDYLSPEMI 269          

HSP 2 Score: 43.8986 bits (102), Expect = 2.634e-45
Identity = 18/37 (48.65%), Postives = 25/37 (67.57%), Query Frame = 2

Query:  470 KEHDYAVDNWTLGILCYELLYGAPPFEAESQKTRSRR 580
            +E+D  VD W LG+L YEL+ G PPFE  S++   +R
Sbjct:  272 REYDEQVDVWALGVLAYELVVGVPPFEENSKELTYKR 308          

HSP 3 Score: 38.891 bits (89), Expect = 2.634e-45
Identity = 21/40 (52.50%), Postives = 30/40 (75.00%), Query Frame = 1

Query:  568 TFXKIMKVDLSFPSAPSISAEDIHLISRLLVKDSSQTLSL 687
            T+ +I+K DL+FP + S  A+D  LIS+LLV D++Q LSL
Sbjct:  305 TYKRILKCDLNFPESISKDAKD--LISKLLVTDTTQRLSL 342          

BLAST of EY692991 vs. ExPASy Swiss-Prot
Match: IPL1_DEBHA (Spindle assembly checkpoint kinase OS=Debaryomyces hansenii GN=IPL1 PE=3 SV=2)

HSP 1 Score: 153.295 bits (386), Expect = 3.685e-45
Identity = 75/152 (49.34%), Postives = 104/152 (68.42%), Query Frame = 3

Query:   27 SKYPVALKIIFKEQIEKYKIQHQLRREMEIQSSLRHPNILRLYGWFHDDERIFLILEYAHRGELYRELRKHRRFTEQQAATYIASLTNALAYCHENHVIHRDIKPENLLLDHEGRLKIGDSGWSVQ----SRSKRHTMCGTLHYLAPEMVDT 470
            S Y  ALK++ K+ +   K++   RRE+EIQS+L HP I RLYG+F+D + ++LILEY+  GELY  L+  RRF +  A+ YI  +  AL Y H  H+IHRDIKPEN+LL  +  +K+ D GWSV+    S +KR T+CGTL YL PEM+++
Sbjct:  170 SGYIAALKVMAKKDLIDLKLEKNFRREIEIQSNLIHPKISRLYGFFYDHKNVYLILEYSIHGELYHHLKVQRRFNDATASHYIYQVALALDYLHTKHIIHRDIKPENILLSTDNCIKLSDFGWSVKSSPSSSTKRLTICGTLDYLPPEMIES 321          

HSP 2 Score: 50.447 bits (119), Expect = 3.685e-45
Identity = 21/36 (58.33%), Postives = 25/36 (69.44%), Query Frame = 2

Query:  473 EHDYAVDNWTLGILCYELLYGAPPFEAESQKTRSRR 580
            EHDY VD W+LGILCYE L G PPFE   + +  +R
Sbjct:  323 EHDYTVDIWSLGILCYEFLVGKPPFEEIDKNSTYKR 358