EY692488

BLAST of EY692488 vs. ExPASy Swiss-Prot
Match: DYR1A_HUMAN (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens GN=DYRK1A PE=1 SV=2)

HSP 1 Score: 125.561 bits (314), Expect = 4.043e-28
Identity = 64/155 (41.29%), Postives = 99/155 (63.87%), Query Frame = 2

Query:  323 DDKDGHYMFALGENLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHD-KGGNRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFM--HDLCMIHTDLKPENVLL 778
            DD +  Y+   GE    RY+I S +G+G+FGQV++ +DR  +E VAIKI++  K +   A IE+ +L+ + KHD +     V ++  F +RNH+C+VFE L  +LYD LR  N+R   ++L R+ A+Q+   + F+   +L +IH DLKPEN+LL
Sbjct:  141 DDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILL 295          

BLAST of EY692488 vs. ExPASy Swiss-Prot
Match: DYRK2_CHICK (Dual specificity tyrosine-phosphorylation-regulated kinase 2 OS=Gallus gallus GN=DYRK2 PE=2 SV=1)

HSP 1 Score: 124.79 bits (312), Expect = 6.896e-28
Identity = 58/153 (37.91%), Postives = 97/153 (63.40%), Query Frame = 2

Query:  323 DDKDGHYMFALGENLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHDKGGN-RCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMHDLCMIHTDLKPENVLL 778
            DD  G Y+    +++  RY++   +G+G+FGQV++ +D +  + VA+K+VR  K++   A  EI +L+ L K DK  N   + +   F +R+HIC+ FE L  +LY+ ++KN ++ F + LVR+ A  +L+C+  +H   +IH DLKPEN+LL
Sbjct:  129 DDDQGSYIQVPHDHIAYRYEVLKVIGKGSFGQVVKAYDHKMHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNNMNVIHMLENFTFRSHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILL 281          

BLAST of EY692488 vs. ExPASy Swiss-Prot
Match: DYR1B_MOUSE (Dual specificity tyrosine-phosphorylation-regulated kinase 1B OS=Mus musculus GN=Dyrk1b PE=1 SV=3)

HSP 1 Score: 124.02 bits (310), Expect = 1.176e-27
Identity = 62/155 (40.00%), Postives = 101/155 (65.16%), Query Frame = 2

Query:  323 DDKDGHYMFALGENLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHD-KGGNRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFM--HDLCMIHTDLKPENVLL 778
            DD +  Y+   GE    RY+I S +G+G+FGQV++ +D + +E+VAIKI++  K +   A IE+ +L+ + +HD +     V ++  F +RNH+C+VFE L  +LYD LR  ++R   ++L R++A+QL   + F+   +L +IH DLKPEN+LL
Sbjct:   93 DDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILL 247          

BLAST of EY692488 vs. ExPASy Swiss-Prot
Match: DYR1B_HUMAN (Dual specificity tyrosine-phosphorylation-regulated kinase 1B OS=Homo sapiens GN=DYRK1B PE=1 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 1.176e-27
Identity = 62/155 (40.00%), Postives = 101/155 (65.16%), Query Frame = 2

Query:  323 DDKDGHYMFALGENLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHD-KGGNRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFM--HDLCMIHTDLKPENVLL 778
            DD +  Y+   GE    RY+I S +G+G+FGQV++ +D + +E+VAIKI++  K +   A IE+ +L+ + +HD +     V ++  F +RNH+C+VFE L  +LYD LR  ++R   ++L R++A+QL   + F+   +L +IH DLKPEN+LL
Sbjct:   93 DDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILL 247          

BLAST of EY692488 vs. ExPASy Swiss-Prot
Match: MBK2_CAEEL (Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2 OS=Caenorhabditis elegans GN=mbk-2 PE=1 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 2.007e-27
Identity = 61/167 (36.53%), Postives = 104/167 (62.28%), Query Frame = 2

Query:  281 VKGLARNGSPPWREDDKDGHYMFALGENLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHDKGG-NRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMHDLCMIHTDLKPENVLL 778
            V G A NG      DD++G Y   + +++  RY++   +G+G+FGQV++ +D + ++ VA+K+VR  K++   A  EI +L  L + D  G +  + + ++F++RNH CI FE L  +LY+ +++N ++ F + LVR+ A  +L C+  +    +IH DLKPENVLL
Sbjct:  433 VIGGANNGG----YDDENGSYQLVVHDHIAYRYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQADEEIRILDHLRRQDSDGTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLL 595          

BLAST of EY692488 vs. ExPASy Swiss-Prot
Match: MBK2_CAEBR (Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2 OS=Caenorhabditis briggsae GN=mbk-2 PE=3 SV=2)

HSP 1 Score: 123.25 bits (308), Expect = 2.007e-27
Identity = 61/167 (36.53%), Postives = 104/167 (62.28%), Query Frame = 2

Query:  281 VKGLARNGSPPWREDDKDGHYMFALGENLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHDKGG-NRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMHDLCMIHTDLKPENVLL 778
            V G A NG      DD++G Y   + +++  RY++   +G+G+FGQV++ +D + ++ VA+K+VR  K++   A  EI +L  L + D  G +  + + ++F++RNH CI FE L  +LY+ +++N ++ F + LVR+ A  +L C+  +    +IH DLKPENVLL
Sbjct:  432 VIGGANNGG----YDDENGSYQLVVHDHIAYRYEVLKVIGKGSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQADEEIRILDHLRRQDSDGTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQGFSLMLVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLL 594          

BLAST of EY692488 vs. ExPASy Swiss-Prot
Match: DYRK2_MOUSE (Dual specificity tyrosine-phosphorylation-regulated kinase 2 OS=Mus musculus GN=Dyrk2 PE=2 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 2.007e-27
Identity = 58/153 (37.91%), Postives = 96/153 (62.75%), Query Frame = 2

Query:  323 DDKDGHYMFALGENLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHDKGGN-RCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMHDLCMIHTDLKPENVLL 778
            DD  G Y+    +++  RY++   +G+G+FGQV++ +D +  + VA+K+VR  K++   A  EI +L+ L K DK      + +   F +RNHIC+ FE L  +LY+ ++KN ++ F + LVR+ A  +L+C+  +H   +IH DLKPEN+LL
Sbjct:  202 DDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILL 354          

BLAST of EY692488 vs. ExPASy Swiss-Prot
Match: DYRK2_HUMAN (Dual specificity tyrosine-phosphorylation-regulated kinase 2 OS=Homo sapiens GN=DYRK2 PE=1 SV=3)

HSP 1 Score: 123.25 bits (308), Expect = 2.007e-27
Identity = 58/153 (37.91%), Postives = 96/153 (62.75%), Query Frame = 2

Query:  323 DDKDGHYMFALGENLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHDKGGN-RCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMHDLCMIHTDLKPENVLL 778
            DD  G Y+    +++  RY++   +G+G+FGQV++ +D +  + VA+K+VR  K++   A  EI +L+ L K DK      + +   F +RNHIC+ FE L  +LY+ ++KN ++ F + LVR+ A  +L+C+  +H   +IH DLKPEN+LL
Sbjct:  204 DDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILL 356          

BLAST of EY692488 vs. ExPASy Swiss-Prot
Match: MNB_DROME (Serine/threonine-protein kinase minibrain OS=Drosophila melanogaster GN=mnb PE=1 SV=2)

HSP 1 Score: 121.324 bits (303), Expect = 7.625e-27
Identity = 62/155 (40.00%), Postives = 99/155 (63.87%), Query Frame = 2

Query:  323 DDKDGHYMFALGENLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHD-KGGNRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMH--DLCMIHTDLKPENVLL 778
            DD +  Y+   GE    RY+I S +G+G+FGQV++ +D E +  VAIKI++  K +   A IE+++L+ + + D +     V+++  F +RNH+C+VFE L  +LYD LR  N+R   ++L R+ A+QL   + F+   +L +IH DLKPEN+LL
Sbjct:  146 DDDNHDYIIKNGEKFLDRYEIDSLIGKGSFGQVVKAYDHEEQCHVAIKIIKNKKPFLNQAQIEVKLLEMMNRADAENKYYIVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQLCTALLFLSTPELNIIHCDLKPENILL 300          

BLAST of EY692488 vs. ExPASy Swiss-Prot
Match: HIPK1_RAT (Homeodomain-interacting protein kinase 1 OS=Rattus norvegicus GN=Hipk1 PE=2 SV=1)

HSP 1 Score: 120.168 bits (300), Expect = 1.699e-26
Identity = 57/153 (37.25%), Postives = 90/153 (58.82%), Query Frame = 2

Query:  332 DGHYMFALGE---NLTSRYKIHSKMGEGTFGQVLECWDRERKEMVAIKIVRGIKKYREAAMIEIEVLQQLAKHDKGGNRCVQIRNWFDYRNHICIVFEKLGSSLYDFLRKNNYRSFPIDLVREIARQLLECIAFMHDLCMIHTDLKPENVLLV 781
            +G Y     E   ++T+ Y++   +G GTFGQV +CW R  KE+VAIKI++    Y     IE+ +L +L+  +      V+    F ++NH C+VFE L  +LYDFL++N +   P+  +R I +Q+   +  +  L +IH DLKPEN++LV
Sbjct:  172 EGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLV 324