EY690948

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: ROS_HUMAN (Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens GN=ROS1 PE=2 SV=3)

HSP 1 Score: 90.1225 bits (222), Expect = 1.752e-17
Identity = 56/160 (35.00%), Postives = 85/160 (53.12%), Query Frame = 1

Query:   43 VKQALDVARGMAYVHGLGFIHRDLKSDNLLIS-----ADKSIKIADFGVAR-------IEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEI 483
            V   +D+++G  Y+  + FIHRDL + N L+S     + + +KI DFG+AR          + EG+ P     RWMAPE +    +T + DV+SFGI++WE++T G  P+   + +      V  G R   P +C   L  +MT+CW   P+ RP F  I
Sbjct: 2057 VDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLP----VRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLD-VLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRI 2211          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: ROCO9_DICDI (Probable serine/threonine-protein kinase roco9 OS=Dictyostelium discoideum GN=roco9 PE=3 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.752e-17
Identity = 48/158 (30.38%), Postives = 84/158 (53.16%), Query Frame = 1

Query:   34 KLAVKQALDVARGMAYVHGL--GFIHRDLKSDNLLISADKSIK----IADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIVR 489
            +L +K A  +A  +  +H      +HRDLKS N+L+S+  S+     + DF ++         + +     W+APE+I +   + K DVY++G++L+EL++    F N+T +     ++ +GVRP +P   LP    ++  CW  +P  RP F EI +
Sbjct: 3105 QLRIKIAKGIAASLQTLHDSRPSVVHRDLKSPNILLSSKDSLTMECHLCDFSLSGFSTTVANRSVQNPV--WLAPEVINNELCSDKSDVYAYGVILFELLSRTRFFSNITFMSEVEGLITEGVRPSLPSHNLPEYDSLLNICWAQDPTCRPSFIEITK 3260          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: KSYK_HUMAN (Tyrosine-protein kinase SYK OS=Homo sapiens GN=SYK PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.752e-17
Identity = 53/166 (31.93%), Postives = 85/166 (51.20%), Query Frame = 1

Query:   13 QNTAVPLKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVAR--------IEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEI 483
            QN  V  K  ++    V+ GM Y+    F+HRDL + N+L+      KI+DFG+++         + QT G  P     +W APE I +  ++ K DV+SFG+++WE  + G  P++ M   +   A++ KG R   P  C   + ++M  CW  + E RP F  +
Sbjct:  462 QNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWP----VKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVT-AMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAV 622          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: KIN15_CAEEL (Receptor-like tyrosine-protein kinase kin-15 OS=Caenorhabditis elegans GN=kin-15 PE=2 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.752e-17
Identity = 54/149 (36.24%), Postives = 91/149 (61.07%), Query Frame = 1

Query:   61 VARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEG---MTPETGT---YRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIV 486
            +A GM Y+  +  +HRDL   N+L++ +K+I+IADFG+AR + Q +G   +T   GT    RWMAPE+++    T+K DV+S+G+ L+E+ + G LP+ N++     F  V +G +  +P  C P + + M + W+ +   RP F++ V
Sbjct:  303 IAEGMEYLASIPCVHRDLALRNVLLNKNKTIRIADFGLAR-KYQVDGYYRITKGVGTPMPARWMAPEVMREGKCTEKSDVWSYGVSLYEMFSLGELPYSNVSN-SDVFEHVVQGNQLPMPQYCHPKMYDRMKQFWNFDATFRPSFSKCV 449          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: GDT2_DICDI (Probable serine/threonine-protein kinase gdt2 OS=Dictyostelium discoideum GN=gdt2 PE=2 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.752e-17
Identity = 50/163 (30.67%), Postives = 91/163 (55.83%), Query Frame = 1

Query:   43 VKQALDVARGMAYVHGLGFIHRDLKSDNLLISA--DKSI---KIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNKGVRPVIPDDCL--PVLSEIMTRCWDTNPEVRPPFTEIVRNA*RMLK 510
            ++  +D+++  AY+H  G  HRDLK +N+LI++   KS+   K++DFG ++   +   +    GT  +M+ E++    YT+  D+YSFG++ +EL +  +P+ +    +    +V K  RP +  +      +S+I+TRCW  NP  RP F  + +    +LK
Sbjct: 1386 IRILIDISKACAYLHRNGITHRDLKPENILITSLNPKSLVCAKVSDFGTSKETNERYNLQTRRGTVAYMSNEILSQGSYTKSTDIYSFGMLCYELFSERIPYYSEPHWRIR-ELVLKNERPSLDQEIFKDTDISDIVTRCWSKNPSQRPTFDYLSKYLKHLLK 1547          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: DDR1_PANTR (Epithelial discoidin domain-containing receptor 1 OS=Pan troglodytes GN=DDR1 PE=3 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.752e-17
Identity = 59/174 (33.91%), Postives = 84/174 (48.28%), Query Frame = 1

Query:   13 QNTAVPLKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVAR-------IEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWE--LITGLLPFQNMTAVQAA------FAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIVR 489
            Q   +   + +  A  +A GM Y+  L F+HRDL + N L+  + +IKIADFG++R         VQ   + P     RWMA E I    +T   DV++FG+ LWE  ++    PF  +T  Q        F    + V    P  C   L E+M RCW    E RPPF+++ R
Sbjct:  730 QGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLP----IRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHR 899          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: DDR1_HUMAN (Epithelial discoidin domain-containing receptor 1 OS=Homo sapiens GN=DDR1 PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.752e-17
Identity = 59/174 (33.91%), Postives = 84/174 (48.28%), Query Frame = 1

Query:   13 QNTAVPLKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVAR-------IEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWE--LITGLLPFQNMTAVQAA------FAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIVR 489
            Q   +   + +  A  +A GM Y+  L F+HRDL + N L+  + +IKIADFG++R         VQ   + P     RWMA E I    +T   DV++FG+ LWE  ++    PF  +T  Q        F    + V    P  C   L E+M RCW    E RPPF+++ R
Sbjct:  734 QGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKIADFGMSRNLYAGDYYRVQGRAVLP----IRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLHR 903          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: STE20_CANAL (Serine/threonine-protein kinase CST20 OS=Candida albicans GN=CST20 PE=3 SV=2)

HSP 1 Score: 89.7373 bits (221), Expect = 2.289e-17
Identity = 43/109 (39.45%), Postives = 67/109 (61.47%), Query Frame = 1

Query:   58 DVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGV-ARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNKG 381
            +  +G+ ++H  G IHRD+KSDN+L++ D +IKI DFG  A+I           GT  WMAPE++  + Y  KVDV+S GI++ E++ G  P+ N T ++A + +   G
Sbjct: 1054 ETLKGLKFLHSKGVIHRDIKSDNILLNMDGNIKITDFGFCAQINEINSKRITMVGTPYWMAPEIVSRKEYGPKVDVWSLGIMIIEMLEGEPPYLNETPLRALYLIATNG 1162          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: PKN5_MYXXA (Serine/threonine-protein kinase pkn5 OS=Myxococcus xanthus GN=pkn5 PE=2 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 2.289e-17
Identity = 42/117 (35.90%), Postives = 67/117 (57.26%), Query Frame = 1

Query:   55 LDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEGMTPE---TGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNKGVRPVI 396
            L +   +AY+HG G +HRDLK  N+++  D+ +++ DFG+A+       +T      GTYR+MAPE I   P   + D+YS G++L+EL++G  PF   T  +    V+     PV+
Sbjct:  226 LQICEALAYIHGHGLVHRDLKPSNIMVDDDRQVRLMDFGLAKFLADDAAITEAGKLVGTYRYMAPEQILGEPLDGRADLYSLGVILYELLSGRPPFDAKTPHELWRQVLETEPPPVL 342          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: ERBB4_MOUSE (Receptor tyrosine-protein kinase erbB-4 OS=Mus musculus GN=Erbb4 PE=1 SV=3)

HSP 1 Score: 89.7373 bits (221), Expect = 2.289e-17
Identity = 51/163 (31.29%), Postives = 86/163 (52.76%), Query Frame = 1

Query:   34 KLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEGMTPETG---TYRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIVRNA*RMLK 510
            +L +   + +A+GM Y+     +HRDL + N+L+ +   +KI DFG+AR+    E      G     +WMA E I +R +T + DV+S+G+ +WEL+T G  P+  +   +    ++ KG R   P  C   +  +M +CW  + + RP F E+     RM +
Sbjct:  818 QLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIP-DLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMAR 979