EY690948

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: DLK1_CAEEL (Mitogen-activated protein kinase kinase kinase dlk-1 OS=Caenorhabditis elegans GN=dlk-1 PE=1 SV=4)

HSP 1 Score: 113.235 bits (282), Expect = 1.933e-24
Identity = 62/160 (38.75%), Postives = 94/160 (58.75%), Query Frame = 1

Query:    7 RPQNTAVPLKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEG-MTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEI 483
            + +NT +  +L  +   ++A GM Y+H    IHRDLKS N+LISA+ SIKI DFG + ++ + +  M    GT  WMAPEMI+ +P  +KVDVYSFG+VLWE++T   P+ N+  +   F V    +   +P++    L  ++ +C       RP F+ I
Sbjct:  213 KSRNT-ITRELFAQWVKEIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHMQKKMDSTMMSFCGTVSWMAPEMIKKQPCNEKVDVYSFGVVLWEMLTRETPYANIAQMAIIFGVGTNILSLPMPEEAPKGLVLLIKQCLSQKGRNRPSFSHI 371          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: DLK1_CAEBR (Mitogen-activated protein kinase kinase kinase dlk-1 OS=Caenorhabditis briggsae GN=dlk-1 PE=3 SV=1)

HSP 1 Score: 113.235 bits (282), Expect = 1.933e-24
Identity = 59/143 (41.26%), Postives = 85/143 (59.44%), Query Frame = 1

Query:   58 DVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEG-MTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEI 483
            ++A GM Y+H    IHRDLKS N+LISA+ SIKI DFG + ++ + +  M    GT  WMAPEMI+  P  +KVDVYSFG+VLWE++T   P+ N+  +   F V    +   +P++    L  ++ +C       RP F+ I
Sbjct:  156 EIADGMHYLHQNKVIHRDLKSPNILISAEDSIKICDFGTSHLQKKNDSTMMSFCGTVSWMAPEMIKKEPCNEKVDVYSFGVVLWEMLTRETPYANIAQMAIIFGVGTNILNLPMPEEAPRGLVLLIKQCLSQKGRNRPSFSHI 298          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: TNI3K_MOUSE (Serine/threonine-protein kinase TNNI3K OS=Mus musculus GN=Tnni3k PE=2 SV=3)

HSP 1 Score: 112.849 bits (281), Expect = 2.524e-24
Identity = 62/151 (41.06%), Postives = 88/151 (58.28%), Query Frame = 1

Query:   52 ALDVARGMAYVHGLG--FIHRDLKSDNLLISADKSIKIADFGVARI--EVQTEGMTPETGTYRWMAPEMI-QHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIVR 489
            A+DVA+GM Y+H L    IHRDL S N+L+  D    +ADFG +R    +  + MT + G  RWMAPE+  Q   YT K DV+S+ + LWEL+ G +PF ++    AA  +    +RP I       +S ++ R W+  PE RP F+E+VR
Sbjct:  566 AVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWELLIGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLMRGWNACPEGRPEFSEVVR 716          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: M313A_XENLA (Mitogen-activated protein kinase kinase kinase 13-A OS=Xenopus laevis GN=map3k13-A PE=2 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 2.524e-24
Identity = 53/151 (35.10%), Postives = 90/151 (59.60%), Query Frame = 1

Query:   34 KLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIV 486
            +L V  +  +A GM Y+H    IHRDLKS N+L++   ++KI+DFG ++            GT  WMAPE+I++ P ++KVD++SFG++LWEL+TG +P++++ +    + V +  +   +P  C      +M + W + P  RP F +I+
Sbjct:  255 RLLVDWSNGIASGMNYLHLHKIIHRDLKSPNVLVTHTDTVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVLLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWHSKPRNRPSFRQIL 405          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: TNI3K_HUMAN (Serine/threonine-protein kinase TNNI3K OS=Homo sapiens GN=TNNI3K PE=1 SV=2)

HSP 1 Score: 112.464 bits (280), Expect = 3.297e-24
Identity = 61/150 (40.67%), Postives = 88/150 (58.67%), Query Frame = 1

Query:   52 ALDVARGMAYVHGLG--FIHRDLKSDNLLISADKSIKIADFGVARI--EVQTEGMTPETGTYRWMAPEMI-QHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIV 486
            A+DVA+GM Y+H L    IHRDL S N+L+  D    +ADFG +R    +  + MT + G  RWMAPE+  Q   YT K DV+S+ + LWE++TG +PF ++    AA  +    +RP I       +S ++ R W+  PE RP F+E+V
Sbjct:  668 AVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISSLLIRGWNACPEGRPEFSEVV 817          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: PYK1_DICDI (Dual specificity protein kinase pyk1 OS=Dictyostelium discoideum GN=splA PE=1 SV=3)

HSP 1 Score: 112.464 bits (280), Expect = 3.297e-24
Identity = 67/174 (38.51%), Postives = 99/174 (56.90%), Query Frame = 1

Query:   13 QNTAVPLKLAVKQALDVARGMAYVHGLG--FIHRDLKSDNLLIS-------------ADKSIKIADFGVARIEV-QTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIV 486
            QN  + LKLA    LD+A+GM Y+HG     +HRDL S N+L+               D   KI+DFG++R+++ Q   MT   G   +MAPE+ +    ++K DVYS+G+VL+EL+T   P Q+M  ++ A     +  RP IP        EI+T+CWD+NP+ RP F +I+
Sbjct: 2213 QNPHIRLKLA----LDIAKGMNYLHGWTPPILHRDLSSRNILLDHNIDPKNPVVSSRQDIKCKISDFGLSRLKMEQASQMTQSVGCIPYMAPEVFKGDSNSEKSDVYSYGMVLFELLTSDEPQQDMKPMKMAHLAAYESYRPPIPLTTSSKWKEILTQCWDSNPDSRPTFKQII 2382          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: FER_RAT (Proto-oncogene tyrosine-protein kinase Fer (Fragment) OS=Rattus norvegicus GN=Fer PE=2 SV=1)

HSP 1 Score: 112.464 bits (280), Expect = 3.297e-24
Identity = 63/164 (38.41%), Postives = 95/164 (57.93%), Query Frame = 1

Query:    7 RPQNTAVPLKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEGMTPETG----TYRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEI 483
            R +   + LK  V+ +LDVA GM Y+ G   IHRDL + N L+  + ++KI+DFG++R E    G+   +G      +W APE + +  Y+ + DV+SFGI+LWE  + G+ P+  MT  QA    V +G R   P +C   +  IM +CWD  PE RP F+++
Sbjct:  151 RKRKDELKLKQLVRFSLDVAAGMLYLEGKNCIHRDLAARNCLVGENNTLKISDFGMSRQE--DGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAR-EQVERGYRMSAPQNCPEEIFTIMMKCWDYKPENRPKFSDL 311          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: M3K13_PONAB (Mitogen-activated protein kinase kinase kinase 13 OS=Pongo abelii GN=MAP3K13 PE=2 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 4.306e-24
Identity = 52/149 (34.90%), Postives = 88/149 (59.06%), Query Frame = 1

Query:   34 KLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTE 480
            +L V  +  +A GM Y+H    IHRDLKS N+L++   ++KI+DFG ++            GT  W+APE+I++ P ++KVD++SFG+VLWEL+TG +P++++ +    + V +  +   +P  C      +M + W + P  RP F +
Sbjct:  254 RLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDKSTKMSFAGTVAWLAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSTCPDGFKILMKQTWQSKPRNRPSFRQ 402          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: IGF1R_XENLA (Insulin-like growth factor 1 receptor OS=Xenopus laevis GN=igf1r PE=1 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 4.306e-24
Identity = 63/173 (36.42%), Postives = 99/173 (57.23%), Query Frame = 1

Query:    1 PTRPQNTAVP---LKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTE-------GMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIV 486
            P    N+  P   LK  ++ A ++A GM+Y++   F+HRDL + N +++ D ++KI DFG+ R   +T+       G+ P     RWM+PE ++   +T   DV+SFG+VLWE+ T    P+Q M+  Q    V+  G+    PD+C  +L E+M  CW  NP++RP F EI+
Sbjct: 1092 PDTESNSGQPTPSLKKMIQMAGEIADGMSYLNANKFVHRDLAARNCMVTEDFTVKIGDFGMTRDIYETDYYRKGGKGLLP----VRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGGLLEK-PDNCPDMLFELMRMCWQFNPKMRPSFLEII 1259          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: FER_HUMAN (Proto-oncogene tyrosine-protein kinase Fer OS=Homo sapiens GN=FER PE=1 SV=2)

HSP 1 Score: 111.309 bits (277), Expect = 7.345e-24
Identity = 64/164 (39.02%), Postives = 93/164 (56.71%), Query Frame = 1

Query:    7 RPQNTAVPLKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEGMTPETG----TYRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEI 483
            R +   + LK  VK +LD A GM Y+     IHRDL + N L+  +  +KI+DFG++R E    G+   +G      +W APE + +  Y+ + DV+SFGI+LWE  + G+ P+  MT  QA    V +G R   P  C   +S+IM +CWD  PE RP F+E+
Sbjct:  650 RRKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQE--DGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAR-EQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSEL 810