EY690948

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: LCK_AOTNA (Proto-oncogene tyrosine-protein kinase LCK OS=Aotus nancymaae GN=LCK PE=2 SV=4)

HSP 1 Score: 109.383 bits (272), Expect = 2.791e-23
Identity = 62/155 (40.00%), Postives = 90/155 (58.06%), Query Frame = 1

Query:   31 LKLAVKQALD----VARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEGMTPETGTY--RWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPF 474
            +KL + + LD    +A GMA++    +IHRDL++ N+L+S   S KIADFG+AR+    E    E   +  +W APE I +  +T K DV+SFGI+L E++T G +P+  MT  +     + +G R V PD+C   L  +M  CW   PE RP F
Sbjct:  334 IKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE-VIQNLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTF 487          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: GDT4_DICDI (Probable serine/threonine-protein kinase gdt4 OS=Dictyostelium discoideum GN=gdt4 PE=3 SV=2)

HSP 1 Score: 109.383 bits (272), Expect = 2.791e-23
Identity = 64/176 (36.36%), Postives = 100/176 (56.82%), Query Frame = 1

Query:    4 TRPQNTAVPLKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISA---DKSI--KIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLP--VLSEIMTRCWDTNPEVRPPFTEIVRNA*RMLK 510
            TR QN  + +   ++ +LD++R  +++H  G IHRDLK DN+LI +   D SI  KI+DFG  R       +  + GT R+M+PE+++  PYT   DVYSF I+ +EL++G +PF+ +   +     V  G RP +  D      +S I+  CW+ NP  RP F  ++    ++LK
Sbjct: 1431 TRNQNIKLSMVQNIRISLDISRACSFLHKNGIIHRDLKPDNVLIVSFDPDSSICAKISDFGTCREINGKHELNSKAGTTRYMSPEILEGLPYTYSTDVYSFAILFFELLSGRVPFREIPKREIP-RFVRLGTRPRLDQDVFADNDISLILLACWNPNPRGRPTFDTLIDLLEKLLK 1605          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: FYN_XENLA (Proto-oncogene tyrosine-protein kinase Fyn OS=Xenopus laevis GN=fyn PE=2 SV=3)

HSP 1 Score: 109.383 bits (272), Expect = 2.791e-23
Identity = 64/158 (40.51%), Postives = 88/158 (55.70%), Query Frame = 1

Query:   13 QNTAVPLKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEGMTPETGT---YRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPF 474
            +  A+ L   V  A  VARGMAY+  + +IHRDL+S N+L+      KIADFG+AR+ ++    T   G     +W APE   +  +T K DV+SFGI+L EL+T G +P+  M   +     V +G R   P DC   L E+M  CW  +PE RP F
Sbjct:  358 EGRALKLPNLVDMAAQVARGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARL-IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNN-REVLEQVERGYRMPCPQDCPISLHELMLNCWKKDPEERPTF 513          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: FGFR1_CHICK (Basic fibroblast growth factor receptor 1 OS=Gallus gallus GN=FGFR1 PE=2 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 2.791e-23
Identity = 71/197 (36.04%), Postives = 104/197 (52.79%), Query Frame = 1

Query:    1 PTRPQNTAVPLKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVAR-------IEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIVRNA*RMLKLRS*QLCVKASLSVLQ*HP 567
            PTR     +  K  V  A  VARGM Y+     IHRDL + N+L++ D  +KIADFG+AR        +  T G  P     +WMAPE +  R YT + DV+SFG++LWE+ T G  P+  +  V+  F ++ +G R   P +C   L  +M  CW   P  RP F ++V +  R++ + S Q  +  S+ + Q  P
Sbjct:  585 PTRIPEEQLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLP----VKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGV-PVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVAMTSNQEYLDLSVPLDQYSP 776          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: FER_MOUSE (Proto-oncogene tyrosine-protein kinase Fer OS=Mus musculus GN=Fer PE=1 SV=2)

HSP 1 Score: 109.383 bits (272), Expect = 2.791e-23
Identity = 62/164 (37.80%), Postives = 93/164 (56.71%), Query Frame = 1

Query:    7 RPQNTAVPLKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEGMTPETG----TYRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEI 483
            R +   + LK  V+ +LDVA GM Y+     IHRDL + N L+  + ++KI+DFG++R E    G+   +G      +W APE + +  Y+ + DV+SFGI+LWE  + G+ P+  MT  QA    V +G R   P +C   +  IM +CWD  PE RP F ++
Sbjct:  651 RKRKDELKLKQLVRFSLDVAAGMLYLESKNCIHRDLAARNCLVGENNTLKISDFGMSRQE--DGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAR-EQVERGYRMSAPQNCPEEVFTIMMKCWDYKPENRPKFNDL 811          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: ROCO5_DICDI (Probable serine/threonine-protein kinase roco5 OS=Dictyostelium discoideum GN=roco5 PE=3 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 3.645e-23
Identity = 60/173 (34.68%), Postives = 97/173 (56.07%), Query Frame = 1

Query:    7 RPQNTAVPLKLAVKQALDVARGMAYVHGLG--FIHRDLKSDNLLISADKSI----KIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGLLPFQNMTAVQAAFAV-----VNKGVRPVIPDDCL---PVLSEIMTRCWDTNPEVRPPFTEI 483
            R   +++  +L +K A+++A  + ++HG      HRDLKS N+L+ +D +     K++DFG  R  V +     +     W++PE+++   YT+K DVYSFGIVLWE++TGLLPF       ++F       +  G+RP IP + +   P    ++T CW  +P  RP F +I
Sbjct: 2264 RKSFSSITWQLKLKIAINIADAIKHMHGFTPKICHRDLKSPNILMLSDMNAAVVCKVSDFGETRAVVTSALGRDKLSNPIWLSPEIMRGDEYTEKADVYSFGIVLWEILTGLLPFDEYPVAHSSFMYQLEDEITNGLRPTIPQNSVCGHPDFITLITDCWQNDPLKRPTFIDI 2436          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: MATK_HUMAN (Megakaryocyte-associated tyrosine-protein kinase OS=Homo sapiens GN=MATK PE=1 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 3.645e-23
Identity = 56/154 (36.36%), Postives = 89/154 (57.79%), Query Frame = 1

Query:   52 ALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIVRNA*RMLK 510
            +L VA GM Y+     +HRDL + N+L+S D   K++DFG+A+ E   +G+       +W APE ++H  +T K DV+SFG++LWE+ + G  P+  M+  + + A V KG R   P+ C   +  +M+ CW+  P  RPPF ++     R L+
Sbjct:  333 SLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAE--RKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEA-VEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLARELR 483          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: LCK_MOUSE (Proto-oncogene tyrosine-protein kinase LCK OS=Mus musculus GN=Lck PE=1 SV=4)

HSP 1 Score: 108.997 bits (271), Expect = 3.645e-23
Identity = 63/155 (40.65%), Postives = 90/155 (58.06%), Query Frame = 1

Query:   31 LKLAVKQALD----VARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTEGMTPETGTY--RWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPF 474
            +KL V + LD    +A GMA++    +IHRDL++ N+L+S   S KIADFG+AR+    E    E   +  +W APE I +  +T K DV+SFGI+L E++T G +P+  MT  +     + +G R V PD+C   L  +M  CW   PE RP F
Sbjct:  334 IKLNVNKLLDMAAQIAEGMAFIEEQNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPE-VIQNLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTF 487          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: INSR_HUMAN (Insulin receptor OS=Homo sapiens GN=INSR PE=1 SV=3)

HSP 1 Score: 108.997 bits (271), Expect = 3.645e-23
Identity = 64/171 (37.43%), Postives = 100/171 (58.48%), Query Frame = 1

Query:    1 PTRPQNTAVPLKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTE-------GMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELITGLL--PFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIV 486
            P RP  T   L+  ++ A ++A GMAY++   F+HRDL + N +++ D ++KI DFG+ R   +T+       G+ P     RWMAPE ++   +T   D++SFG+VLWE IT L   P+Q ++  Q    V++ G     PD+C   ++++M  CW  NP++RP F EIV
Sbjct: 1126 PGRPPPT---LQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLP----VRWMAPESLKDGVFTTSSDMWSFGVVLWE-ITSLAEQPYQGLSNEQVLKFVMDGGYLDQ-PDNCPERVTDLMRMCWQFNPKMRPTFLEIV 1287          

BLAST of EY690948 vs. ExPASy Swiss-Prot
Match: IGF1R_RAT (Insulin-like growth factor 1 receptor OS=Rattus norvegicus GN=Igf1r PE=2 SV=2)

HSP 1 Score: 108.997 bits (271), Expect = 3.645e-23
Identity = 59/160 (36.88%), Postives = 94/160 (58.75%), Query Frame = 1

Query:   31 LKLAVKQALDVARGMAYVHGLGFIHRDLKSDNLLISADKSIKIADFGVARIEVQTE-------GMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNKGVRPVIPDDCLPVLSEIMTRCWDTNPEVRPPFTEIV 486
            L   ++ A ++A GMAY++   F+HRDL + N +++ D ++KI DFG+ R   +T+       G+ P     RWM+PE ++   +T   DV+SFG+VLWE+ T    P+Q ++  Q    V+  G+    PD+C  +L E+M  CW  NP++RP F EI+
Sbjct: 1110 LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLP----VRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDK-PDNCPDMLFELMRMCWQYNPKMRPSFLEII 1264