EY685218

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: HERC2_MOUSE (Probable E3 ubiquitin-protein ligase HERC2 OS=Mus musculus GN=Herc2 PE=1 SV=2)

HSP 1 Score: 88.5817 bits (218), Expect = 5.657e-17
Identity = 54/167 (32.34%), Postives = 90/167 (53.89%), Query Frame = 3

Query:  144 GRNIKVTEENKHQDVDLVAEH-RLTTAIR-----PQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQ-KFQIHKAYGSIDH-LPSAHTCFNQLDLPGIS 620
            G++I+++ ++ H  +D  AE+ RL    R      Q+ A  EG   ++P  L+S+F   ELE ++ G PDI L  +++   Y G   ++ ++QWFWEV++ FS  +++  L+FV G +++P      +    G     Q+   Y   DH LP ++TCF  L LP  S
Sbjct: 4612 GQDIQLSSKHTHITLDNRAEYVRLAINYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSASLVQWFWEVMESFSNTERSLFLRFVWGRTRLP----RTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFLLKLPRYS 4774          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: HECD3_HUMAN (Probable E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens GN=HECTD3 PE=1 SV=1)

HSP 1 Score: 86.6557 bits (213), Expect = 2.150e-16
Identity = 51/185 (27.57%), Postives = 95/185 (51.35%), Query Frame = 3

Query:   57 DLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            +LTF+    +++++          ELIPGG  I V   ++ + + LV + RL  + + Q+ A   G  +++P  ++ +   +ELE  + G P++ +D +R  T +  +  +   +Q+FWE +  F+ ED++R L+FVTG S++P   +           +     Y + D LP + TC + L LP
Sbjct:  667 ELTFTTVLSDQQVV----------ELIPGGAGIVVGYGDRSRFIQLVQKARLEES-KEQVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALRKLTRFEDFEPSDSRVQYFWEALNNFTNEDRSRFLRFVTGRSRLPARIYI----------YPDKLGYETTDALPESSTCSSTLFLP 830          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: UFD4_YEAST (Ubiquitin fusion degradation protein 4 OS=Saccharomyces cerevisiae GN=UFD4 PE=1 SV=1)

HSP 1 Score: 82.4185 bits (202), Expect = 4.054e-15
Identity = 66/220 (30.00%), Postives = 106/220 (48.18%), Query Frame = 3

Query:    6 LLQNLKWMLENDISDV----LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTE---------LIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQI---HKAYG--SIDHLPSAHTCFNQLDLP 611
            L ++LK+++ N   ++    L LTF++  ++            D ELIPGG N  +   N  + +  V +  L   I  Q+ AF+EGF++         L P EL+ IF   E +  ++ L          N E+ GY+  S +I  F  ++  F K ++   LQF+TG+ K+P+ GF +L     + KF +   H   G  + ++LPS  TC N L LP
Sbjct: 1262 LAKSLKYIVANKDDNMTLESLSLTFTVPGND------------DIELIPGGCNKSLNSSNVEEYIHGVIDQILGKGIEKQLKAFIEGFSKVFSYERMLILFPDELVDIFGRVEEDWSMATLYT------NLNAEH-GYTMDSSIIHDFISIISAFGKHERRLFLQFLTGSPKLPIGGFKSL-----NPKFTVVLKHAEDGLTADEYLPSVMTCANYLKLP 1457          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: HERC6_HUMAN (Probable E3 ubiquitin-protein ligase HERC6 OS=Homo sapiens GN=HERC6 PE=2 SV=2)

HSP 1 Score: 82.4185 bits (202), Expect = 4.054e-15
Identity = 55/196 (28.06%), Postives = 89/196 (45.41%), Query Frame = 3

Query:   36 NDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEY-SGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLPGIS 620
            +DI D L + FSI  D+            D +LIP G +I V + NK   V    ++    +++     F  GF  +   E++  F  +EL   I G  D D      N++Y  GY  + P IQ FW+     + ++K + L F+TG  ++   G   ++ +     F+  + +   DH P++ TC N L LP  S
Sbjct:  817 DDIGDALCIRFSIHWDQN-----------DVDLIPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIGNTDYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIV-----FRCPETFSERDH-PTSITCHNILSLPKYS 995          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: HYD_DROME (E3 ubiquitin-protein ligase hyd OS=Drosophila melanogaster GN=hyd PE=1 SV=3)

HSP 1 Score: 80.8777 bits (198), Expect = 1.180e-14
Identity = 57/209 (27.27%), Postives = 106/209 (50.72%), Query Frame = 3

Query:    6 LLQNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASP-----VIQWFWEVVQGFSKEDKARLLQFVTGTSKVPL--EGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            ++QN +     +  + ++L F ID  +E+          + ELIPGGR++ VT  N  + V    E+RL  +    + A  +G  +++P   +     ++L LL++G+ DI++  + + T ++  S+  P       +WFW +V+  +  ++  L+ F TG+  +P   EGF  L  ++      I  A  S  HLP+A+TC ++L +P
Sbjct: 2668 IIQNAQTKEGEETINRMELCFVIDLMKEE-------GCGNRELIPGGRDVAVTSSNIFEYVRRYTEYRLIKSQEKALEALKDGVFDVLPDNSMINLTAEDLRLLLNGVGDINVSTLISYTTFNDESSEGPDKLLKFKKWFWSIVEKMNIMERQDLVYFWTGSPALPASEEGFQPLPSVT------IRPADDS--HLPTANTCISRLYIP 2861          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: MUG30_SCHPO (Probable E3 ubiquitin-protein ligase mug30 OS=Schizosaccharomyces pombe GN=mug30 PE=1 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 4.482e-14
Identity = 63/228 (27.63%), Postives = 99/228 (43.42%), Query Frame = 3

Query:    6 LLQNLKWML--ENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDI------------DLDDMRA-------------NTEYSGYSAAS--PVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQL 602
            L + LK +L  E D+ +   L F+I+       L         EL  GG  + V  EN+ + V    ++ L T ++ Q +AF +GF ++  G  IS+F D E+  LI G  ++            D  D  A              ++Y  +S  S   +I WFW+++  +S + +   L FVTG+ ++P  G    Q        +I       D LP +HTCFN L
Sbjct:  566 LYRGLKELLLFEGDVKNTYGLNFTIN-------LKAVEGFRTVELKEGGSELSVDNENRKEYVLRYVDYLLNTTVKKQFSAFFDGFMKVCGGNAISLFQDNEISKLIRGSEEVIDWELLKNVCVYDFYDQNAISNSISESEPSMTASKYLCHSFVSKRKIILWFWDLISHYSLKMQKLFLIFVTGSDRIPATGAHNFQ-------LRISVLGPDSDQLPISHTCFNHL 779          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: HERC2_DROME (Probable E3 ubiquitin-protein ligase HERC2 OS=Drosophila melanogaster GN=HERC2 PE=1 SV=3)

HSP 1 Score: 78.5666 bits (192), Expect = 5.854e-14
Identity = 46/174 (26.44%), Postives = 89/174 (51.15%), Query Frame = 3

Query:  102 YERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSAASPVIQWFWEVVQGFSKEDKARLLQFVTGTSKVPLEGFSALQGISGSQ-KFQIHKAYGSIDHLPSAHTCFNQLDLPGIS 620
            +  +    +E+    R   ++  N+ + V L    RL      Q+ A  +G +++IP  L+S+F+  EL+ ++ G PDI L  +++   Y G+  +S ++ WFWEV++ F+ ++++  L+FV G +++P      +    G     Q+ +       LP ++TCF  L +P  S
Sbjct: 4692 FSTSSARGHEVPLSTRYTHISPRNRAEYVRLALGFRLHE-FDEQVKAVRDGMSKVIPVPLLSLFSAAELQAMVCGSPDIPLGLLKSVATYKGFDPSSALVTWFWEVMEEFTNQERSLFLRFVWGRTRLP----RTIADFRGRDFVLQVLEKNPPDHFLPESYTCFFLLKMPRYS 4860          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: UBR5_MOUSE (E3 ubiquitin-protein ligase UBR5 OS=Mus musculus GN=Ubr5 PE=1 SV=2)

HSP 1 Score: 78.1814 bits (191), Expect = 7.646e-14
Identity = 54/197 (27.41%), Postives = 98/197 (49.75%), Query Frame = 3

Query:   42 ISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSA--ASPVIQ---WFWEVVQGFSKEDKARLLQFVTGTSKVPL--EGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            +   +DL F+ID  +E+       QV   ELIP G NI VT +N ++ V   AEHR+       ++A  +G  +++P   +     ++  LL++G  ++++  + + T ++  S   A  ++Q   WFW +V+  S  ++  L+ F T +  +P   EGF  +  I+               HLP+A+TC ++L +P
Sbjct: 2587 VFSAMDLAFAIDLCKEE----GGGQV---ELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPP--------DDQHLPTANTCISRLYVP 2768          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: UBR5_HUMAN (E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens GN=UBR5 PE=1 SV=2)

HSP 1 Score: 78.1814 bits (191), Expect = 7.646e-14
Identity = 54/197 (27.41%), Postives = 98/197 (49.75%), Query Frame = 3

Query:   42 ISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSA--ASPVIQ---WFWEVVQGFSKEDKARLLQFVTGTSKVPL--EGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            +   +DL F+ID  +E+       QV   ELIP G NI VT +N ++ V   AEHR+       ++A  +G  +++P   +     ++  LL++G  ++++  + + T ++  S   A  ++Q   WFW +V+  S  ++  L+ F T +  +P   EGF  +  I+               HLP+A+TC ++L +P
Sbjct: 2594 VFSAMDLAFAIDLCKEE----GGGQV---ELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPP--------DDQHLPTANTCISRLYVP 2775          

BLAST of EY685218 vs. ExPASy Swiss-Prot
Match: UBR5_RAT (E3 ubiquitin-protein ligase UBR5 (Fragment) OS=Rattus norvegicus GN=Ubr5 PE=2 SV=2)

HSP 1 Score: 77.7962 bits (190), Expect = 9.985e-14
Identity = 53/197 (26.90%), Postives = 98/197 (49.75%), Query Frame = 3

Query:   42 ISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQDVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDKELELLISGLPDIDLDDMRANTEYSGYSA--ASPVIQ---WFWEVVQGFSKEDKARLLQFVTGTSKVPL--EGFSALQGISGSQKFQIHKAYGSIDHLPSAHTCFNQLDLP 611
            +   +DL F++D  +E+       QV   ELIP G NI VT +N ++ V   AEHR+       ++A  +G  +++P   +     ++  LL++G  ++++  + + T ++  S   A  ++Q   WFW +V+  S  ++  L+ F T +  +P   EGF  +  I+               HLP+A+TC ++L +P
Sbjct:  715 VFSAMDLAFAVDLCKEE----GGGQV---ELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVERMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPP--------DDQHLPTANTCISRLYVP 896