EY744726

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: CDK10_DICDI (Probable cyclin-dependent kinase 10 OS=Dictyostelium discoideum GN=cdk10 PE=2 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 3.654e-13
Identity = 50/151 (33.11%), Postives = 77/151 (50.99%), Query Frame = 2

Query:   71 EVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQP--TARSVIGTPEFMAPELYE--EEYNELVDIYSFGMCILEMV 511
            E+ +LK +KH NI+      +  T   I ++ E             +K   +  IK +  Q+LR + YLHSH   IIHRDLKC N+ + GNNG +K+ D GLA     P  +    + T  + +PEL    ++Y+  VD++S G    E++
Sbjct:   55 EIQILKEIKHPNIVSLLEVVIGSTGDKIYLVFEYLEHDVASLIDNINKPFKLSEIKCFLLQLLRAVEYLHSHW--IIHRDLKCSNL-LYGNNGNLKLADFGLARKFGYPIESITPCMVTLWYRSPELLLGCQKYSTAVDLWSIGSIFGELL 202          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: PPK34_SCHPO (Serine/threonine-protein kinase ppk34 OS=Schizosaccharomyces pombe GN=ppk34 PE=2 SV=2)

HSP 1 Score: 75.485 bits (184), Expect = 4.773e-13
Identity = 52/182 (28.57%), Postives = 90/182 (49.45%), Query Frame = 2

Query:   11 DQVNIQDVMQSPDQLERLY---SEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLR--QYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLA-IVMQQPTARSVIGTPEFMAPELYEEEYNEL----VDIYSFGMCILEMVTCEVP 526
            D   I+D +++ ++ +  Y    E+ +LK L HEN++K Y     D   ++ M+      G L    +      + ++  +   RQ++  ++Y+H     +IHRD+K DNI    NN    I D GLA  + +    +   GTP FMAPEL++ E  ++    +DI+S G+ +  +   E P
Sbjct:   98 DSSTIEDQIRNQEKKDPYYYIRKELDVLKVLDHENVVKLYQVINSDYKDSLCMVLNYCPGGKLASVDHGISFDPMPLETCRKSFRQLVLAVNYIHGKG--VIHRDIKPDNILFKENNNLCVI-DFGLAEFLPKDGFVKPASGTPAFMAPELFDNELKKIKGKPLDIWSMGVTLYVIAFAEFP 276          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: NAK1_SCHPO (Serine/threonine-protein kinase nak1 OS=Schizosaccharomyces pombe GN=nak1 PE=1 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 4.773e-13
Identity = 58/177 (32.77%), Postives = 93/177 (52.54%), Query Frame = 2

Query:   17 VNIQDVMQSPDQLERLYSEVHLLKSLKH---ENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQPTARSV--IGTPEFMAPELYE--EEYNELVDIYSFGMCILEMVTCEVP 526
            + I ++    D++  +  EV +L  LK    ENIIK++ S++  TN  I  I +    GS+R   +    +    I    R+ L+ L ++H  +  IIHRD+K  NI V+  +G VK+ D G+A  +     + +  IGTP +MAPE+    +EYN + DI+S G+   E+ T   P
Sbjct:   38 IKILNLDTDEDEVSDIQKEVAVLSELKQSDVENIIKYHGSYLVGTNLWI--IMDYCHGGSVRTLMEAGP-ISEPCISLILRETLQALKFIH--HAGIIHRDIKAANILVS-MSGNVKLCDFGVAAELNINRRKRITFIGTPYWMAPEVIRDGQEYNVMADIWSLGITAYEIATGSPP 208          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: MP2K5_HUMAN (Dual specificity mitogen-activated protein kinase kinase 5 OS=Homo sapiens GN=MAP2K5 PE=1 SV=2)

HSP 1 Score: 75.485 bits (184), Expect = 4.773e-13
Identity = 52/169 (30.77%), Postives = 91/169 (53.85%), Query Frame = 2

Query:   56 ERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQPTARSVIGTPEFMAPE-LYEEEYNELVDIYSFGMCILEMVTCEVPI**LQKSTSNI 559
            +++ SE+ +L       II FY ++  +    I++ TE    GSL  YRK  ++V    +   A  +++GL YL S    I+HRD+K  N+ VN   G+VK+ D G++  +    A++ +GT  +MAPE +  E+Y    D++S G+  +E+     P   +QK+  ++
Sbjct:  207 KQIMSELEILYKCDSSYIIGFYGAFFVENR--ISICTEFMDGGSLDVYRKMPEHV----LGRIAVAVVKGLTYLWSLK--ILHRDVKPSNMLVN-TRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSL 366          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: MARK2_RAT (Serine/threonine-protein kinase MARK2 OS=Rattus norvegicus GN=Mark2 PE=1 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 4.773e-13
Identity = 48/171 (28.07%), Postives = 89/171 (52.05%), Query Frame = 2

Query:   23 IQDVMQSPDQLERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQPTARSVI-GTPEFMAPELYE-EEYN-ELVDIYSFGMCILEMVTCEVP 526
            I     +   L++L+ EV ++K L H NI+K +   V +T +T+ ++ E  + G +  Y   H  +  K  +   RQI+  + Y H     I+HRDLK +N+ ++ +   +KI D G +             G+P + APEL++ ++Y+   VD++S G+ +  +V+  +P
Sbjct:   84 IDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFE--VIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF--IVHRDLKAENLLLDADM-NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLP 249          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: MARK2_HUMAN (Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2)

HSP 1 Score: 75.485 bits (184), Expect = 4.773e-13
Identity = 48/171 (28.07%), Postives = 89/171 (52.05%), Query Frame = 2

Query:   23 IQDVMQSPDQLERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQPTARSVI-GTPEFMAPELYE-EEYN-ELVDIYSFGMCILEMVTCEVP 526
            I     +   L++L+ EV ++K L H NI+K +   V +T +T+ ++ E  + G +  Y   H  +  K  +   RQI+  + Y H     I+HRDLK +N+ ++ +   +KI D G +             G+P + APEL++ ++Y+   VD++S G+ +  +V+  +P
Sbjct:   84 IDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFE--VIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKF--IVHRDLKAENLLLDADM-NIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLP 249          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: LIMK2_CHICK (LIM domain kinase 2 OS=Gallus gallus GN=LIMK2 PE=2 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 4.773e-13
Identity = 50/187 (26.74%), Postives = 101/187 (54.01%), Query Frame = 2

Query:   23 IQDVMQSPDQLERLY-SEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIV---------MQQPTAR-------------SVIGTPEFMAPELYE-EEYNELVDIYSFGMCILEMV 511
            ++++++  ++ ++ + +EV +++SL H N++KF      D  + +N++TE    G+L+ + +       +   ++A+ I  G+ YLHS    IIHRDL   N  +  +   V + D GL+ +         +++P+A+             +V+G P +MAPE+   + Y+E VDI+SFG+ + E++
Sbjct:  359 MKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKD--KKLNLLTEYIEGGTLKDFLRNADPFPWQQKVSFAKGIASGMAYLHS--MCIIHRDLNSHNCLIKLDK-TVVVADFGLSRLIVEERKKPTLEKPSAKKRTLRKSDRKKRYTVVGNPYWMAPEMLNGQSYDETVDIFSFGIVLCEII 540          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: KPC1_CAEEL (Protein kinase C-like 1 OS=Caenorhabditis elegans GN=tpa-1 PE=2 SV=2)

HSP 1 Score: 75.485 bits (184), Expect = 4.773e-13
Identity = 51/172 (29.65%), Postives = 95/172 (55.23%), Query Frame = 2

Query:   26 QDVMQSPDQLERLYSEVH-LLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLA---IVMQQPTARSVIGTPEFMAPELYEEE-YNELVDIYSFGMCILEMVTCEVP 526
            +DV+   D  E  Y E   L+ + +   + + + S+   TN  +  + E    G L  + ++ K  D    + +A +I+  L +LH++N  II+RDLK DN+ ++ + G +K+ D G+A   +  +   A +  GTP++++PE+ + + YNE VD +SFG+ + EM+  + P
Sbjct:  408 KDVILEDDDTECTYIERRVLILASQCPFLCQLFCSF--QTNEYLFFVMEYLNGGDLMHHIQQIKKFDEARTRFYACEIVVALQFLHTNN--IIYRDLKLDNVLLDCD-GHIKLADFGMAKTEMNRENGMASTFCGTPDYISPEIIKGQLYNEAVDFWSFGVLMYEMLVGQSP 574          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: DSOR1_DROME (Dual specificity mitogen-activated protein kinase kinase dSOR1 OS=Drosophila melanogaster GN=Dsor1 PE=2 SV=2)

HSP 1 Score: 75.485 bits (184), Expect = 4.773e-13
Identity = 52/159 (32.70%), Postives = 82/159 (51.57%), Query Frame = 2

Query:   56 ERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQPTARSVIGTPEFMAPE-LYEEEYNELVDIYSFGMCILEMVTCEVPI 529
            +++  E+ +L      +I+ FY ++  D   +I M  E    GSL    K+   +    +      +L+GL YL   N  IIHRD+K  NI VN ++GE+KI D G++  +    A S +GT  +M+PE L    Y+   DI+S G+ ++EM     PI
Sbjct:  128 KQILRELKVLHECNFPHIVGFYGAFYSDGEISICM--EYMDGGSLDLILKRAGRIPESILGRITLAVLKGLSYLRD-NHAIIHRDVKPSNILVN-SSGEIKICDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSLGLSLVEMAIGMYPI 282          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: BMR1A_MOUSE (Bone morphogenetic protein receptor type-1A OS=Mus musculus GN=Bmpr1a PE=2 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 4.773e-13
Identity = 55/168 (32.74%), Postives = 83/168 (49.40%), Query Frame = 2

Query:   68 SEVHLLKSLKHENIIKFYNSWVDDTNR--TINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSH------NPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQPT------ARSVIGTPEFMAPELYEEEYNE-------LVDIYSFGMCILEM 508
            +E++    ++HENI+ F  + +  T     + +IT+   +GSL  + K    +D +A+   A     GL +LH+        P I HRDLK  NI +   NG   I DLGLA+     T        + +GT  +MAPE+ +E  N+       + DIYSFG+ I EM
Sbjct:  275 TEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFLKC-ATLDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIAHRDLKSKNILIK-KNGSCCIADLGLAVKFNSDTNEVDIPLNTRVGTKRYMAPEVLDESLNKNHFQPYIMADIYSFGLIIWEM 440