EY744726

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: M3K15_MOUSE (Mitogen-activated protein kinase kinase kinase 15 OS=Mus musculus GN=Map3k15 PE=3 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 1.434e-17
Identity = 60/161 (37.27%), Postives = 85/161 (52.80%), Query Frame = 2

Query:   62 LYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQY-RKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLA--IVMQQPTARSVIGTPEFMAPELYEE---EYNELVDIYSFGMCILEMVTCEVP 526
            L+ E+ L K LKH NI+++  S  +  N  I +  E    GSL    R K   +    IK + +QIL GL YLH +   I+HRD+K DN+ VN  +G VKI D G +  +    P   +  GT ++MAPE+ ++    Y    DI+S G  I+EM T   P
Sbjct:  698 LHEEIALHKYLKHRNIVQYLGSVSE--NGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQ--IVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSRPP 854          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: M2K2_ARATH (Mitogen-activated protein kinase kinase 2 OS=Arabidopsis thaliana GN=MKK2 PE=1 SV=2)

HSP 1 Score: 90.5077 bits (223), Expect = 1.434e-17
Identity = 60/174 (34.48%), Postives = 96/174 (55.17%), Query Frame = 2

Query:   14 QVNIQDVMQSPDQLERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQPT--ARSVIGTPEFMAPE-LYEEEYNELVDIYSFGMCILEMVTCEVP 526
            Q+NI + ++     + +  E+ + +S +  N++  Y S+ D  N  I++I E    GSL  + K  K +    +    RQ+L+GL YLH H+  IIHRDLK  N+ +N + GEVKI D G++ VM      A + +GT  +M+PE +   +Y    DI+S G+ +LE  T + P
Sbjct:  102 QLNIDEAIR-----KAIAQELKINQSSQCPNLVTSYQSFYD--NGAISLILEYMDGGSLADFLKSVKAIPDSYLSAIFRQVLQGLIYLH-HDRHIIHRDLKPSNLLIN-HRGEVKITDFGVSTVMTNTAGLANTFVGTYNYMSPERIVGNKYGNKSDIWSLGLVVLECATGKFP 266          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: YR818_MIMIV (Putative serine/threonine-protein kinase/receptor R818 OS=Acanthamoeba polyphaga mimivirus GN=MIMI_R818 PE=4 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.872e-17
Identity = 58/160 (36.25%), Postives = 91/160 (56.88%), Query Frame = 2

Query:   50 QLERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQPTARSVIGTPEFMAPELYE-EEYNELVDIYSFGMCILEMVTCEVP 526
            Q+    +E+  L  L+H +II    + +   N  I ++TE   +GSLR   K  K      IK   +  L G+ YLH+ +P IIHRD+K  NI V+ ++  VKI D G A + ++ +  +  GTP + APE+   E+Y E VD++SFG+ + E++TC+ P
Sbjct: 1432 QMLEFRAEIAFLSQLRHPHIILMIGACLKRPN--ICIVTEFMGNGSLRNVIKTTKPEWKLKIKMLYQTAL-GIGYLHNSDPIIIHRDIKPSNILVD-DSMNVKIADFGFARIKEENSVMTRCGTPCWTAPEIIRGEKYTEKVDVFSFGIVMWEVLTCKEP 1587          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: NEK8_MOUSE (Serine/threonine-protein kinase Nek8 OS=Mus musculus GN=Nek8 PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.872e-17
Identity = 54/160 (33.75%), Postives = 98/160 (61.25%), Query Frame = 2

Query:   47 DQLERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKN--VDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLA-IVMQQPTARSVIGTPEFMAPELYE-EEYNELVDIYSFGMCILEMVT 514
            ++ +   +E  +LK L H N+I++Y ++++D    I M  E    G+L ++ +K  N  ++ + I ++  QIL  LH++H+H   I+HRDLK  NI ++ +   VKIGD G++ I+  +  A +V+GTP +++PEL E + YN+  DI++ G  + E+ +
Sbjct:   43 EERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAM--EYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL--ILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELAS 198          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: NEK8_HUMAN (Serine/threonine-protein kinase Nek8 OS=Homo sapiens GN=NEK8 PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.872e-17
Identity = 54/160 (33.75%), Postives = 98/160 (61.25%), Query Frame = 2

Query:   47 DQLERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKN--VDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLA-IVMQQPTARSVIGTPEFMAPELYE-EEYNELVDIYSFGMCILEMVT 514
            ++ +   +E  +LK L H N+I++Y ++++D    I M  E    G+L ++ +K  N  ++ + I ++  QIL  LH++H+H   I+HRDLK  NI ++ +   VKIGD G++ I+  +  A +V+GTP +++PEL E + YN+  DI++ G  + E+ +
Sbjct:   43 EERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAM--EYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHL--ILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELAS 198          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: KRAF1_CAEBR (Raf homolog serine/threonine-protein kinase OS=Caenorhabditis briggsae GN=lin-45 PE=3 SV=2)

HSP 1 Score: 90.1225 bits (222), Expect = 1.872e-17
Identity = 65/192 (33.85%), Postives = 103/192 (53.65%), Query Frame = 2

Query:    5 ASDQVNIQDVMQSPDQLERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQY---RKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIV-----------MQQPTARSVIGTPEFMAPELY----EEEYNELVDIYSFGMCILEMVTCEVP 526
            A  ++N+ D   +P Q+    +EV +LK  +H N++ F   WV +    I +IT+     SL ++   ++     +M A+ +  +Q+  G++YLHS N  IIHRDLK +NIF+  +   VKIGD GLA V            QQPT     G+  +MAPE+     +  Y    D+YSFG+C+ E+++  +P
Sbjct:  503 AIKKLNVVD--PTPSQMAAFKNEVAVLKKTRHLNVLLFMG-WVREPE--IAIITQWCEGSSLYRHIHVQEPRVEFEMSAVIDILKQVSLGMNYLHSKN--IIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQQQQQPT-----GSILWMAPEVIRMQDDNPYTPQSDVYSFGVCMYEILSSHLP 682          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: YR831_MIMIV (Putative serine/threonine-protein kinase/receptor R831 OS=Acanthamoeba polyphaga mimivirus GN=MIMI_R831 PE=4 SV=2)

HSP 1 Score: 89.7373 bits (221), Expect = 2.445e-17
Identity = 61/167 (36.53%), Postives = 90/167 (53.89%), Query Frame = 2

Query:   41 SPDQLERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQIL----RGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQPTARSVIGTPEFMAPELYE-EEYNELVDIYSFGMCILEMVTCEVP 526
            S  QL    +E+  L  LKH NI+ F  + +   N  I ++TE    G+LR   K   N D+K       ++L     G+ YLHS NP I+HRD+K  NI V+  +  VKI D G A + +  T  +  GTP + APE+   E+Y E  D++SFG+ + E++T + P
Sbjct: 1399 SETQLLEFRAEMAFLSELKHSNIVTFIGACIKKPN--ICIVTEYMRMGNLRDVLK---NPDIKITFANKLKLLYGAAMGIDYLHSSNPMIVHRDIKPANILVD-EHFNVKIADFGFARIKEDNTTMTRCGTPCWTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEP 1559          

HSP 2 Score: 73.1738 bits (178), Expect = 2.369e-12
Identity = 55/171 (32.16%), Postives = 87/171 (50.88%), Query Frame = 2

Query:   41 SPDQLERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMK-AIK-NWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQ----PTARSVIGTPEFMAPELYEEEYNE---LVDIYSFGMCILEMVTCEVP 526
            S D     + EV ++ SL+H N++ F  +     N  I M  E  + GSL          ++  A+K   A Q  +G+H+LHS    I+HRDLK  N+ ++ +   VK+ D GL  V  +     T  ++IGT  ++APE+  +       L D+YSFG+ + E++T E P
Sbjct:  821 SKDMERSFFEEVKIMTSLRHPNVVLFMAASTKSPNMCIVM--EFMSLGSLYDLLGNELIPEIPYALKIKMAYQASKGMHFLHSSG--IVHRDLKSLNLLLD-SKWNVKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGIILWELLTREQP 986          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: PLK1_BOVIN (Serine/threonine-protein kinase PLK1 OS=Bos taurus GN=PLK1 PE=2 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 2.445e-17
Identity = 58/186 (31.18%), Postives = 104/186 (55.91%), Query Frame = 2

Query:   26 QDVMQSPDQLERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQPTAR--SVIGTPEFMAPELYEEEYNEL-VDIYSFGMCILEMVTCEVPI**LQKSTSNI*ESYL 574
            + ++  P Q E++  E+ + +SL H++++ F+  + D  N  + ++ EL    SL +  K+ K +     + + RQI+ G  YLH +   +IHRDLK  N+F+N  + EVKIGD GLA  ++    R  ++ GTP ++APE+  ++ +   VD++S G  +  ++  + P       TS + E+YL
Sbjct:   84 KSLLLKPHQKEKMSMEISIHRSLAHQHVVGFHGFFED--NDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHGNR--VIHRDLKLGNLFLN-EDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPF-----ETSCLKETYL 259          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: PAKM_DROME (Serine/threonine-protein kinase PAK mbt OS=Drosophila melanogaster GN=mbt PE=1 SV=2)

HSP 1 Score: 89.7373 bits (221), Expect = 2.445e-17
Identity = 55/167 (32.93%), Postives = 93/167 (55.69%), Query Frame = 2

Query:   35 MQSPDQLERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQYRKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIVMQQ--PTARSVIGTPEFMAPELYEE-EYNELVDIYSFGMCILEMVTCEVP 526
            ++   + E L++EV +++   H NI++ Y+S++   N  + ++ E    G+L      H  +D + I    +Q L+ L YLHS    +IHRD+K D+I +   +G VK+ D G    + Q  P  +S++GTP +M+PE+     Y   VDI+S G+ ++EMV  E P
Sbjct:  401 LRKQQRRELLFNEVVIMRDYHHPNIVETYSSFL--VNDELWVVMEYLEGGALTDI-VTHSRMDEEQIATVCKQCLKALAYLHSQG--VIHRDIKSDSILL-AADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMVDGEPP 561          

BLAST of EY744726 vs. ExPASy Swiss-Prot
Match: KRAF1_CAEEL (Raf homolog serine/threonine-protein kinase OS=Caenorhabditis elegans GN=lin-45 PE=1 SV=2)

HSP 1 Score: 89.7373 bits (221), Expect = 2.445e-17
Identity = 66/192 (34.38%), Postives = 103/192 (53.65%), Query Frame = 2

Query:    5 ASDQVNIQDVMQSPDQLERLYSEVHLLKSLKHENIIKFYNSWVDDTNRTINMITELFTSGSLRQY---RKKHKNVDMKAIKNWARQILRGLHYLHSHNPPIIHRDLKCDNIFVNGNNGEVKIGDLGLAIV-----------MQQPTARSVIGTPEFMAPELY----EEEYNELVDIYSFGMCILEMVTCEVP 526
            A  ++N+ D   +P Q+    +EV +LK  +H N++ F   WV +    I +IT+     SL ++   ++     +M AI +  +Q+  G++YLHS N  IIHRDLK +NIF+  +   VKIGD GLA V            QQPT     G+  +MAPE+     +  Y    D+YSFG+C+ E+++  +P
Sbjct:  505 AIKKLNVVD--PTPSQMAAFKNEVAVLKKTRHLNVLLFMG-WVREPE--IAIITQWCEGSSLYRHIHVQEPRVEFEMGAIIDILKQVSLGMNYLHSKN--IIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQQQQQPT-----GSILWMAPEVIRMQDDNPYTPQSDVYSFGICMYEILSSHLP 684