EY664099

BLAST of EY664099 vs. ExPASy Swiss-Prot
Match: SHKA_DICDI (Dual specificity protein kinase shkA OS=Dictyostelium discoideum GN=shkA PE=2 SV=1)

HSP 1 Score: 165.622 bits (418), Expect = 3.089e-40
Identity = 94/207 (45.41%), Postives = 127/207 (61.35%), Query Frame = 3

Query:   48 DIPWNDLVLKEKIGAGSFGTVHHADWHGSDVAVKILMEQEFHAERFKEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKPGVREMLDERRRLNMAYDVAKGMNYLHRRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLK---ANTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDIYSFWCILWELATLQ 659
            +I   ++  +  +G GSFGTV+       DVAVK++++Q    +   +F +EVAIM ++ HPNIVLF+GA T  P   ++   L +G+L  LL  P V+  L  R R  MA D A G+ +LH  NP  +HRDLK+ NLLVD   TVKVCDFGLS++K    N       A GTP WMAPEVL+    NEK+D+YSF  +LW++ T Q
Sbjct:   39 EISETEITTESILGDGSFGTVYKGRCRLKDVAVKVMLKQ-VDQKTLTDFRKEVAIMSKIFHPNIVLFLGACTSTPGKLMICTELMKGNLESLLLDPMVKLPLITRMR--MAKDAALGVLWLHSSNPVFIHRDLKTSNLLVDANLTVKVCDFGLSQIKQRGENLKDGQDGAKGTPLWMAPEVLQGRLFNEKADVYSFGLVLWQIFTRQ 242          

HSP 2 Score: 21.557 bits (44), Expect = 3.089e-40
Identity = 7/16 (43.75%), Postives = 10/16 (62.50%), Query Frame = 2

Query:  761 IMEACWANEPWKRPSF 808
            +++ CW   P  RPSF
Sbjct:  278 LIQKCWDPNPEVRPSF 293          

BLAST of EY664099 vs. ExPASy Swiss-Prot
Match: YR826_MIMIV (Putative serine/threonine-protein kinase/receptor R826 OS=Acanthamoeba polyphaga mimivirus GN=MIMI_R826 PE=4 SV=2)

HSP 1 Score: 163.696 bits (413), Expect = 1.190e-39
Identity = 73/201 (36.32%), Postives = 129/201 (64.18%), Query Frame = 3

Query:   51 IPWNDLVLKEKIGAGSFGTVHHADWHGSDVAVKILMEQEFHAERFKEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKPGVREMLDERRRLNMAYDVAKGMNYLHRRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKANTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDIYSFWCILWELAT 653
            I ++++ + E+IG GS+G V+   W   DVA+K  ++Q+           E+A +K+L HPNI+  +GA  + PN+ IVTEY+++G+L   +        L+  +++ +  ++AKG++YLH  +PPI+HRD+K  N+L+D+ + VK+ DFG +R+K    + ++   GTP W APE++R++  +EK D++SF  ++WE+ T
Sbjct: 1394 INYDEIKMGEQIGLGSYGVVYRGKWKNVDVAIKKFIKQKIDENHLLGIREEIAFLKKLHHPNIITMVGASLKKPNICIVTEYMAKGNLRDAMRT--CTPKLEWHQKIKILVNIAKGISYLHSFDPPIIHRDIKPSNILIDENWNVKIADFGFARIKEENAIMTR--CGTPCWTAPEIIRNDIYDEKVDVFSFGIVMWEVLT 1590          

HSP 2 Score: 162.155 bits (409), Expect = 1.945e-39
Identity = 88/209 (42.11%), Postives = 137/209 (65.55%), Query Frame = 3

Query:   39 DDLDIPWNDLVLKEKIGAGSFGTVHHADWHGSDVAVKILM-EQEFHAERFKEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKPGVREMLDERRRLNMAYDVAKGMNYLHRRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKANT-FLSSKSAAGTPEWMAPEVLRDEPSNE--KSDIYSFWCILWELAT 653
            DD +I +++L L E++G G+FG VH   W G++VAVK++  ++    +  + F  EV +M  LRHPN+VLFM A T+PP + IV E+++ GSL+ LL    + + +    ++ +AY  +KGM++LH  +  I HRDLKS NLL+D K+ VKV DFGL++ K++   ++ +  AGT +W APE+L ++   +   SD+YSF  I+WEL T
Sbjct:  777 DDWEIDFHELELGEQLGTGAFGEVHKGTWRGTEVAVKMISPDKTITKDIERNFKDEVRVMTTLRHPNVVLFMAASTKPPKMCIVMEFMALGSLHDLLKNELIPD-IPFALKVKIAYQASKGMHFLH--SSGITHRDLKSLNLLLDIKWNVKVSDFGLTKFKSDVKSINPEKFAGTIQWTAPEILSEDREVDYILSDVYSFGIIMWELIT 982          

HSP 3 Score: 22.3274 bits (46), Expect = 1.945e-39
Identity = 7/21 (33.33%), Postives = 12/21 (57.14%), Query Frame = 2

Query:  746 PPVASIMEACWANEPWKRPSF 808
            P    ++ +CW  +P  RP+F
Sbjct: 1018 PEYIELLTSCWHFDPTIRPTF 1038          

BLAST of EY664099 vs. ExPASy Swiss-Prot
Match: YR818_MIMIV (Putative serine/threonine-protein kinase/receptor R818 OS=Acanthamoeba polyphaga mimivirus GN=MIMI_R818 PE=4 SV=1)

HSP 1 Score: 160.614 bits (405), Expect = 3.301e-39
Identity = 85/235 (36.17%), Postives = 137/235 (58.30%), Query Frame = 3

Query:   51 IPWNDLVLKEKIGAGSFGTVHHADWHGSDVAVKILMEQEFHAERFKEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLH--KPGVREMLDERRRLNMAYDVAKGMNYLHRRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKANTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDIYSFWCILWELATLQHXWGNLKSGTGCSSWWFSGQEA*DSRNEIP 749
            I ++D+ + ++IG GS+G V+   W   +VAVK  ++Q+   ++  EF  E+A + +LRHP+I+L +GA  + PN+ IVTE++  GSL  ++   KP      + + ++ M Y  A G+ YLH  +P I+HRD+K  N+LVD    VK+ DFG +R+K     S  +  GTP W APE++R E   EK D++SF  ++WE+ T +  +      +GC+    S      +R +IP
Sbjct: 1389 INYDDIQIGKQIGVGSYGIVNMGKWKNINVAVKKFVKQKIDEKQMLEFRAEIAFLSQLRHPHIILMIGACLKRPNICIVTEFMGNGSLRNVIKTTKP------EWKLKIKMLYQTALGIGYLHNSDPIIIHRDIKPSNILVDDSMNVKIADFGFARIKEEN--SVMTRCGTPCWTAPEIIRGEKYTEKVDVFSFGIVMWEVLTCKEPF------SGCNFMKVSMDILEGARPQIP 1609          

HSP 2 Score: 23.0978 bits (48), Expect = 3.301e-39
Identity = 8/15 (53.33%), Postives = 11/15 (73.33%), Query Frame = 2

Query:  761 IMEACWANEPWKRPS 805
            +M+ CW  +P KRPS
Sbjct: 1619 LMKQCWHAKPDKRPS 1633          

HSP 3 Score: 160.999 bits (406), Expect = 7.714e-39
Identity = 90/210 (42.86%), Postives = 132/210 (62.86%), Query Frame = 3

Query:   39 DDLDIPWNDLVLKEKIGAGSFGTVHHADWHGSDVAVKILMEQEFHAERFKEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKPGVREMLDERRRLNMAYDVAKGMNYLHRRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKANT---FLSSKSAAGTPEWMAPEVLRDEPSNE--KSDIYSFWCILWELAT 653
            D+ ++ +++L   E +G+G  G V  A W G++VAVK L+      +  + F +E+  M  LRHPN+VLFM A T+PPN+ IV E++S GSLY LL    V E +    R+ +AY  AKGM++LH  +  IVHRDLKS NLL+D K+ VKV DFGL+++K N      + + +  + +W APEVL ++   +   +D+YSF  I+WEL T
Sbjct:  784 DEWEVDFHELDFMESLGSGGSGEVFKAMWKGTEVAVKKLVNSNITKDAERNFKQEIHRMTSLRHPNVVLFMAASTRPPNMCIVMEFMSLGSLYDLLGNELVTE-IPPVLRIRIAYQAAKGMHFLH--SSDIVHRDLKSLNLLLDSKWNVKVSDFGLTKIKDNNKGKSSTKEDSVCSIQWTAPEVLSEKQDIDYILADVYSFGIIMWELMT 990          

BLAST of EY664099 vs. ExPASy Swiss-Prot
Match: SHKB_DICDI (Dual specificity protein kinase shkB OS=Dictyostelium discoideum GN=shkB PE=3 SV=1)

HSP 1 Score: 158.303 bits (399), Expect = 1.630e-38
Identity = 89/220 (40.45%), Postives = 139/220 (63.18%), Query Frame = 3

Query:   30 FDVDDLDIPWNDLVLKEKIGAGSFGTVHHADWHGSDVAVKILMEQEFHAERFKEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLH-KPGVREMLDERRRLNMAYDVAKGMNYLHRRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSR-LKANTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDIYSFWCILWELATLQHXWGNLKS 683
            +++D  +I +N    + K+G+G+FG+V+     G +VA+K L +  F      EF +EV++M +LR+P+++LFMGA T P +LSIVTE + +GS++ LL  K    + +  +R + +A D   GM +LH  N  I+H DLK  NLLVD+ + VKV DFGLS+ +K ++       AG+P +MAPE+L ++P + K D++SF  +LWEL T Q  +  L S
Sbjct:  165 WEIDRNEISYNR---EAKLGSGAFGSVYKGIVRGKEVAIKKLTQTVFEENTMNEFKKEVSLMAKLRNPHLLLFMGACTAPEDLSIVTELMPKGSVHSLLRAKEDTSDFITFKRAILIARDTVLGMTWLHASN--ILHLDLKPANLLVDQNWVVKVADFGLSKYMKPDSKDKLLGQAGSPLYMAPEMLVNQPYDGKVDVFSFSILLWELLTKQEPYNKLYS 379          

HSP 2 Score: 23.0978 bits (48), Expect = 1.630e-38
Identity = 7/17 (41.18%), Postives = 12/17 (70.59%), Query Frame = 2

Query:  761 IMEACWANEPWKRPSFS 811
            ++  CW + P +RPSF+
Sbjct:  408 LLARCWDHYPSRRPSFA 424          

BLAST of EY664099 vs. ExPASy Swiss-Prot
Match: Y9963_DICDI (Probable serine/threonine-protein kinase DDB_G0272254 OS=Dictyostelium discoideum GN=DDB_G0272254 PE=3 SV=1)

HSP 1 Score: 150.984 bits (380), Expect = 7.906e-38
Identity = 85/207 (41.06%), Postives = 127/207 (61.35%), Query Frame = 3

Query:   51 IPWNDLVLKEKIGAGSFGTVHHADWHGSDVAVKILMEQEFHA--ERFKEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLH-KPGVREM---LDERRRLNMAYDVAKGMNYLHRRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKANTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDIYSFWCILWELAT 653
            I ++D+ + ++IG G F  V   +W G DVAVK L   +  A  E  +EF  EV ++  L+HPN+V   G    P  + IV E+L  G+L+ L+H KP  ++    LD    L +A+D+A+GM +LH RN  I+HRDLKS NLL+DK + +K+ D G++R    +F  + +  GT  W APE+LR E  N+K+D+YS+  +L+EL T
Sbjct: 1068 INYSDIKIDKEIGKGHFSKVLKGNWKGKDVAVKKLNSNKDKAREEMIQEFKAEVELLGSLQHPNLVTCYGYSLNP--MCIVMEFLPSGNLFELIHSKPSEQQQSIKLDSTLILAIAFDIARGMQHLHTRN--IIHRDLKSSNLLMDKHFNIKIADLGIAR--ETSFTQTMTTIGTVAWTAPEILRHESYNQKADVYSYAIVLYELLT 1268          

HSP 2 Score: 28.1054 bits (61), Expect = 7.906e-38
Identity = 10/18 (55.56%), Postives = 12/18 (66.67%), Query Frame = 2

Query:  773 CWANEPWKRPSFSTSWNY 826
            CW+ +P KRPSF    NY
Sbjct: 1309 CWSEDPNKRPSFEEITNY 1326          

BLAST of EY664099 vs. ExPASy Swiss-Prot
Match: ABL_DROME (Tyrosine-protein kinase Abl OS=Drosophila melanogaster GN=Abl PE=1 SV=3)

HSP 1 Score: 150.214 bits (378), Expect = 5.422e-36
Identity = 87/208 (41.83%), Postives = 123/208 (59.13%), Query Frame = 3

Query:   39 DDLDIPWNDLVLKEKIGAGSFGTVHHADW--HGSDVAVKILMEQEFHAERFKEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKPGVREMLDERRRLNMAYDVAKGMNYLHRRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKANTFLSSKSAAGTP-EWMAPEVLRDEPSNEKSDIYSFWCILWELAT 653
            D+ +I   D+++K K+G G +G V+ A W  +G+ VAVK L E        K+FL E AIMK ++HPN+V  +G  T+ P   I+TE++S G+L   L   G RE LD    L MA  +A GM+YL  RN   +HRDL + N LV     VKV DFGL+RL  +   ++ + A  P +W APE L     + KSD+++F  +LWE+AT
Sbjct:  362 DEWEICRTDIMMKHKLGGGQYGEVYEAVWKRYGNTVAVKTLKEDTM---ALKDFLEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAG-RETLDAVALLYMATQIASGMSYLESRN--YIHRDLAARNCLVGDNKLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNKFSTKSDVWAFGVLLWEIAT 563          

HSP 2 Score: 22.7126 bits (47), Expect = 5.422e-36
Identity = 8/23 (34.78%), Postives = 12/23 (52.17%), Query Frame = 2

Query:  746 PPVASIMEACWANEPWKRPSFST 814
            P V  +M  CW  +   RP+F +
Sbjct:  595 PEVYDLMRQCWQWDATDRPTFKS 617          

BLAST of EY664099 vs. ExPASy Swiss-Prot
Match: MLTK_MOUSE (Mitogen-activated protein kinase kinase kinase MLT OS=Mus musculus GN=Mltk PE=1 SV=1)

HSP 1 Score: 149.058 bits (375), Expect = 7.119e-36
Identity = 88/206 (42.72%), Postives = 118/206 (57.28%), Query Frame = 3

Query:   45 LDIPWNDLVLKEKIGAGSFGTVHHADWHGSD--VAVKILMEQEFHAERFKEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKPGVREMLDERRRLNMAYDVAKGMNYLHRRNP-PIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKANTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDIYSFWCILWELAT 653
            + I ++DL   E  G GSFG+V+ A W   D  VAVK L++ E  AE          I+  L H NI+ F G + +PPN  IVTEY S GSLY  ++     EM D    +  A DVAKGM+YLH   P  ++HRDLKS N+++     +K+CDFG SR   +T  +  S  GT  WMAPEV++  P +E  D YS+  +LWE+ T
Sbjct:    9 VQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAE----------ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEM-DMEHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHT--THMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLT 201          

HSP 2 Score: 23.483 bits (49), Expect = 7.119e-36
Identity = 8/18 (44.44%), Postives = 11/18 (61.11%), Query Frame = 2

Query:  755 ASIMEACWANEPWKRPSF 808
            A ++  CW  +  KRPSF
Sbjct:  236 AELLHQCWEADAKKRPSF 253          

BLAST of EY664099 vs. ExPASy Swiss-Prot
Match: MLTK_HUMAN (Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2)

HSP 1 Score: 148.288 bits (373), Expect = 1.208e-35
Identity = 88/206 (42.72%), Postives = 118/206 (57.28%), Query Frame = 3

Query:   45 LDIPWNDLVLKEKIGAGSFGTVHHADWHGSD--VAVKILMEQEFHAERFKEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKPGVREMLDERRRLNMAYDVAKGMNYLHRRNP-PIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKANTFLSSKSAAGTPEWMAPEVLRDEPSNEKSDIYSFWCILWELAT 653
            + I ++DL   E  G GSFG+V+ A W   D  VAVK L++ E  AE          I+  L H NI+ F G + +PPN  IVTEY S GSLY  ++     EM D    +  A DVAKGM+YLH   P  ++HRDLKS N+++     +K+CDFG SR   +T  +  S  GT  WMAPEV++  P +E  D YS+  +LWE+ T
Sbjct:    9 VQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIEKEAE----------ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEM-DMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHT--THMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLT 201          

HSP 2 Score: 23.483 bits (49), Expect = 1.208e-35
Identity = 8/18 (44.44%), Postives = 11/18 (61.11%), Query Frame = 2

Query:  755 ASIMEACWANEPWKRPSF 808
            A ++  CW  +  KRPSF
Sbjct:  236 AELLHQCWEADAKKRPSF 253          

BLAST of EY664099 vs. ExPASy Swiss-Prot
Match: RAF1_CHICK (RAF proto-oncogene serine/threonine-protein kinase OS=Gallus gallus GN=RAF1 PE=2 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 1.362e-35
Identity = 87/207 (42.03%), Postives = 136/207 (65.70%), Query Frame = 3

Query:   48 DIPWNDLVLKEKIGAGSFGTVHHADWHGSDVAVKILMEQEFHAERFKEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKPGVREMLDERRRLNMAYDVAKGMNYLHRRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKANTFLSS--KSAAGTPEWMAPEVLRDEPSNE---KSDIYSFWCILWELAT 653
            +I  ++++L  +IG+GSFGTV+   WHG DVAVKIL   +   E+F+ F  EVA++++ RH NI+LFMG +T+  NL+IVT++    SLY+ LH    +  + +   +++A   A+GM+YLH +N  I+HRD+KS N+ + +  TVK+ DFGL+ +K+    S   +   G+  WMAPEV+R + SN    +SD+YS+  +L+EL T
Sbjct:  343 EIEASEVMLSTRIGSGSFGTVYKGKWHG-DVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQ--LIDIARQTAQGMDYLHAKN--IIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMT 543          

BLAST of EY664099 vs. ExPASy Swiss-Prot
Match: BRAF1_MOUSE (B-Raf proto-oncogene serine/threonine-protein kinase OS=Mus musculus GN=Braf PE=1 SV=2)

HSP 1 Score: 150.214 bits (378), Expect = 1.362e-35
Identity = 89/232 (38.36%), Postives = 142/232 (61.21%), Query Frame = 3

Query:    3 TRPRTRGFTFDVDDLDIPWNDLVLKEKIGAGSFGTVHHADWHGSDVAVKILMEQEFHAERFKEFLREVAIMKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKPGVREMLDERRRLNMAYDVAKGMNYLHRRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKANTFLSS--KSAAGTPEWMAPEVLRDEPSNE---KSDIYSFWCILWELATLQHXWGNLKS 683
            +R +T G     DD +IP   + + ++IG+GSFGTV+   WHG DVAVK+L       ++ + F  EV ++++ RH NI+LFMG  T+ P L+IVT++    SLY  LH   +    +  + +++A   A+GM+YLH ++  I+HRDLKS N+ + +  TVK+ DFGL+ +K+    S   +  +G+  WMAPEV+R +  N    +SD+Y+F  +L+EL T Q  + N+ +
Sbjct:  473 SRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHI--IETKFEMIKLIDIARQTAQGMDYLHAKS--IIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINN 698