EY659673

BLAST of EY659673 vs. ExPASy Swiss-Prot
Match: M3K12_HUMAN (Mitogen-activated protein kinase kinase kinase 12 OS=Homo sapiens GN=MAP3K12 PE=1 SV=2)

HSP 1 Score: 69.707 bits (169), Expect = 2.636e-11
Identity = 43/148 (29.05%), Postives = 75/148 (50.68%), Query Frame = 1

Query:  124 QNEVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLAITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVV 567
            + ++  L  + HPN++   G         I+ E      L   L     G  +T  + +  ++  A G+ YLH H    +IHRDLKS N+L+      K+SDFG +  + S     +  +GT+ ++APE + +  +++K D+++FGVV
Sbjct:  159 ETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRA---GRPVTPSLLVDWSMGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTS-KELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVV 299          

BLAST of EY659673 vs. ExPASy Swiss-Prot
Match: LCK_RAT (Proto-oncogene tyrosine-protein kinase LCK OS=Rattus norvegicus GN=Lck PE=2 SV=3)

HSP 1 Score: 69.707 bits (169), Expect = 2.636e-11
Identity = 47/147 (31.97%), Postives = 78/147 (53.06%), Query Frame = 1

Query:  130 EVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLA-ITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVV 567
            E +L+  + HP +V L      +   +I+ E MEN SL   L  PS G  L  +  + +A   A G+ ++ E      IHRDL+++NIL+    + K++DFGLA + + ++          + + APE +  G  T KSDV++FG++
Sbjct:  288 EANLMKQLQHPRLVRLYAVVTQEPI-YIITEYMENGSLVDFLKTPS-GIKLNVNKLLDMAAQIAEGMAFIEEQ---NYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGIL 429          

BLAST of EY659673 vs. ExPASy Swiss-Prot
Match: LCK_MOUSE (Proto-oncogene tyrosine-protein kinase LCK OS=Mus musculus GN=Lck PE=1 SV=4)

HSP 1 Score: 69.707 bits (169), Expect = 2.636e-11
Identity = 47/147 (31.97%), Postives = 78/147 (53.06%), Query Frame = 1

Query:  130 EVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLA-ITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVV 567
            E +L+  + HP +V L      +   +I+ E MEN SL   L  PS G  L  +  + +A   A G+ ++ E      IHRDL+++NIL+    + K++DFGLA + + ++          + + APE +  G  T KSDV++FG++
Sbjct:  288 EANLMKQLQHPRLVRLYAVVTQEPI-YIITEYMENGSLVDFLKTPS-GIKLNVNKLLDMAAQIAEGMAFIEEQ---NYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGIL 429          

BLAST of EY659673 vs. ExPASy Swiss-Prot
Match: FES_FSVST (Tyrosine-protein kinase transforming protein Fes OS=Feline sarcoma virus (strain Snyder-Theilen) GN=V-FES PE=3 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 2.636e-11
Identity = 47/148 (31.76%), Postives = 74/148 (50.00%), Query Frame = 1

Query:  130 EVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLA--ITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVV 567
            E  +L    HPN+V L+G        +IV EL++       L   + G+ L     +++  D A G+EYL   C    IHRDL + N L+  K   K+SDFG++    DG    +       + + APE L  G+ + +SDV++FG++
Sbjct:  262 EAKILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLR--TEGARLRMKTLLQMVGDAAAGMEYLESKC---CIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLRLVPVKWTAPEALNYGRYSSESDVWSFGIL 404          

BLAST of EY659673 vs. ExPASy Swiss-Prot
Match: ARK1_SCHPO (Serine/threonine-protein kinase ark1 OS=Schizosaccharomyces pombe GN=ark1 PE=1 SV=2)

HSP 1 Score: 69.707 bits (169), Expect = 2.636e-11
Identity = 47/148 (31.76%), Postives = 74/148 (50.00%), Query Frame = 1

Query:  124 QNEVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLAITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVV 567
            + E+++ SN+ H N++ L G+  HD+ R  +Y ++E                 +  +  K     A  L YLH+     VIHRD+K  NILL      KLSDFG ++   S  +    L GTL Y+ PE +   + T+K D+++ GV+
Sbjct:  135 RREIEIQSNLRHKNILRLYGHF-HDEKR--IYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLHKK---HVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNRRTT--LCGTLDYLPPEMVEGKEHTEKVDLWSLGVL 274          

BLAST of EY659673 vs. ExPASy Swiss-Prot
Match: ANKK1_HUMAN (Ankyrin repeat and protein kinase domain-containing protein 1 OS=Homo sapiens GN=ANKK1 PE=1 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 2.636e-11
Identity = 47/125 (37.60%), Postives = 64/125 (51.20%), Query Frame = 1

Query:  211 IVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLA----ITDGSQNKNNLKLSGTLGYVAPEYLLDGKLT--DKSDVYAFGVV 567
            IV E M N SL+  L   S    L W +R +I  +T+  + +LH    P ++H DLK  NILLDS  + K+SDFGL+     +   Q      L G L Y+ PE  L+       K DVY+F +V
Sbjct:   96 IVMEFMANGSLEKVLSTHS----LCWKLRFRIIHETSLAMNFLHS-IKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIERSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIV 215          

BLAST of EY659673 vs. ExPASy Swiss-Prot
Match: Y9957_DICDI (Probable serine/threonine-protein kinase DDB_G0276181 OS=Dictyostelium discoideum GN=DDB_G0276181 PE=3 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 3.442e-11
Identity = 52/167 (31.14%), Postives = 83/167 (49.70%), Query Frame = 1

Query:  127 NEVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDS-----KFNAKLSDFGLAIT------------DGSQNKNNLKLS---GTLGYVAPEYLLDGKLTDKSDVYAFGVV 567
            NEV +LS  +HPNVV  +G         IV E +   +L   L  P     + + + +++ALD A+GL YLH   +  ++H D+KS N+L+ S     K N K++DF   I              GS + N ++     GT  ++APE +     ++K DVY+F ++
Sbjct: 1079 NEVRVLSMFNHPNVVKYVGGCTKIANWSIVMEYVPGGNLMDVLANPV--LVIPYKLVLRMALDIAKGLHYLH---SLGILHLDMKSPNLLVSSLSTSAKVNIKVADFNTCINRSRITAGFFNRHTGSGDNNKVEKDSKKGTTLWMAPEVIRGAMYSEKCDVYSFAII 1240          

BLAST of EY659673 vs. ExPASy Swiss-Prot
Match: STE20_MAGGR (Serine/threonine-protein kinase MST20 OS=Magnaporthe grisea GN=MST20 PE=3 SV=2)

HSP 1 Score: 69.3218 bits (168), Expect = 3.442e-11
Identity = 45/148 (30.41%), Postives = 74/148 (50.00%), Query Frame = 1

Query:  127 NEVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSL-DIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLAITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVV 567
            NE+ ++ +  HPN+V  +         ++V E ME  SL D+        + +T      +  +T  GL++LH   +  VIHRD+KS NILL  + N KL+DFG   T          + GT  ++APE +   +   K D+++ G++
Sbjct:  678 NEILVMKDSSHPNIVNFIDSYLCGGELWVVMEFMEGGSLTDVVTF-----NIMTEGQIASVCRETLLGLQHLH---SKGVIHRDIKSDNILLSMEGNIKLTDFGFCATINEAQNKRTTMVGTPYWMAPEVVTRKEYGRKVDIWSLGIM 817          

BLAST of EY659673 vs. ExPASy Swiss-Prot
Match: STE20_ASHGO (Serine/threonine-protein kinase STE20 OS=Ashbya gossypii GN=STE20 PE=3 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 3.442e-11
Identity = 46/148 (31.08%), Postives = 72/148 (48.65%), Query Frame = 1

Query:  127 NEVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSL-DIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGLAITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVV 567
            NE+ ++    H N+V  +         +++ E ME  SL D+  H       LT      ++ +T RGL +LH   +  VIHRD+KS NILL    N KL+DFG        N     + GT  ++APE +   +   K D+++ G++
Sbjct:  727 NEILVMKGSRHNNIVNFIDSYLLKGDLWVIMEYMEGGSLTDVVTH-----CILTEGQIAAVSRETLRGLHFLH---SKGVIHRDIKSDNILLSMDGNIKLTDFGFCAQINETNLKRTTMVGTPYWMAPEVVSRKEYGPKVDIWSLGIM 866          

BLAST of EY659673 vs. ExPASy Swiss-Prot
Match: PKNB_LACLA (Probable serine/threonine-protein kinase pknB OS=Lactococcus lactis subsp. lactis GN=pknB PE=3 SV=1)

HSP 1 Score: 69.3218 bits (168), Expect = 3.442e-11
Identity = 40/150 (26.67%), Postives = 78/150 (52.00%), Query Frame = 1

Query:  124 QNEVDLLSNIHHPNVVCLLGYSAHDDTRFIVYELMENRSLDIQLHGPSHGSALTWHMRMKIALDTARGLEYLHEHCNPAVIHRDLKSSNILLDSKFNAKLSDFGL--AITDGSQNKNNLKLSGTLGYVAPEYLLDGKLTDKSDVYAFGVV 567
            Q E   ++ + HPN+V +      +  ++IV E ++  +L   ++     + L     ++I  +    ++  H H    +IHRDLK  N+L+ S    K++DFG+  A+++ S  + N  + G++ Y++PE       T +SD+YA G++
Sbjct:   59 QREAFAMAELSHPNIVGISDVGEFESQQYIVMEFVDGMTLKQYIN---QNAPLANDEAIEIITEILSAMDMAHSH---GIIHRDLKPQNVLVSSSGTVKVTDFGIAKALSETSLTQTN-TMFGSVHYLSPEQARGSNATVQSDIYAIGII 201