EY659176

BLAST of EY659176 vs. ExPASy Swiss-Prot
Match: CDK10_RAT (Cell division protein kinase 10 OS=Rattus norvegicus GN=Cdk10 PE=2 SV=1)

HSP 1 Score: 282.722 bits (722), Expect = 2.149e-75
Identity = 142/257 (55.25%), Postives = 193/257 (75.10%), Query Frame = 2

Query:   41 VVSVQRSMNMLHGCRSVFEFEKLNKISEGTYGIVYRARDKKSGEIVALKKVKMNVGRKEDCLEYGFPISSLREINILLSFDHPSIVNVKEVVMDDH-DSVYMVMEYMEHDLKWLMESMKQPFSTSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNQGVLKICDFGMSRQYGSPLKPYTSLVVTLWYRAPELLLGAKKYSTAVDMWXSGCIMAELLAKNPCLVGTTEVDQMDRIFKTLSTSTETIGPGFLELP 808
            + ++  S+  L  CRSV EFEKLN+I EGTYGIVYRARD ++ EIVALKKV+M+  +++D    G PISSLREI +LL   HP+IV +KEVV+ +H +S+++VM Y E DL  L+E+M  PFS ++VKC++LQ+L G++YLH ++++HRDLK SNLL+ ++G +K  DFG++R YG P+KP T  VVTLWYRAPELLLG    +T++DMW  GCI+AELLA  P L GT+E+ Q+D I + L T +E I PGF +LP
Sbjct:   18 IPTLAASLFQLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMD--KEKD----GIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCILLQVLRGLQYLHRSFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLP 268          

BLAST of EY659176 vs. ExPASy Swiss-Prot
Match: CDK10_HUMAN (Cell division protein kinase 10 OS=Homo sapiens GN=CDK10 PE=1 SV=1)

HSP 1 Score: 282.722 bits (722), Expect = 2.149e-75
Identity = 141/244 (57.79%), Postives = 187/244 (76.64%), Query Frame = 2

Query:   80 CRSVFEFEKLNKISEGTYGIVYRARDKKSGEIVALKKVKMNVGRKEDCLEYGFPISSLREINILLSFDHPSIVNVKEVVMDDH-DSVYMVMEYMEHDLKWLMESMKQPFSTSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNQGVLKICDFGMSRQYGSPLKPYTSLVVTLWYRAPELLLGAKKYSTAVDMWXSGCIMAELLAKNPCLVGTTEVDQMDRIFKTLSTSTETIGPGFLELP 808
            CRSV EFEKLN+I EGTYGIVYRARD ++ EIVALKKV+M+  +++D    G PISSLREI +LL   HP+IV +KEVV+ +H +S+++VM Y E DL  L+E+M  PFS ++VKC++LQ+L G++YLH N+++HRDLK SNLL+ ++G +K  DFG++R YG P+KP T  VVTLWYRAPELLLG    +T++DMW  GCI+AELLA  P L GT+E+ Q+D I + L T +E I PGF +LP
Sbjct:   33 CRSVKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMD--KEKD----GIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLP 270          

BLAST of EY659176 vs. ExPASy Swiss-Prot
Match: CDK10_BOVIN (Cell division protein kinase 10 OS=Bos taurus GN=CDK10 PE=2 SV=1)

HSP 1 Score: 281.952 bits (720), Expect = 3.665e-75
Identity = 141/244 (57.79%), Postives = 186/244 (76.23%), Query Frame = 2

Query:   80 CRSVFEFEKLNKISEGTYGIVYRARDKKSGEIVALKKVKMNVGRKEDCLEYGFPISSLREINILLSFDHPSIVNVKEVVMDDH-DSVYMVMEYMEHDLKWLMESMKQPFSTSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNQGVLKICDFGMSRQYGSPLKPYTSLVVTLWYRAPELLLGAKKYSTAVDMWXSGCIMAELLAKNPCLVGTTEVDQMDRIFKTLSTSTETIGPGFLELP 808
            CRSV EFEKLN+I EGTYGIVYRARD  + EIVALKKV+M+  +++D    G PISSLREI +LL   HP+IV +KEVV+ +H +S+++VM Y E DL  L+E+M  PFS ++VKC++LQ+L G++YLH N+++HRDLK SNLL+ ++G +K  DFG++R YG P+KP T  VVTLWYRAPELLLG    +T++DMW  GCI+AELLA  P L GT+E+ Q+D I + L T +E I PGF +LP
Sbjct:   31 CRSVKEFEKLNRIGEGTYGIVYRARDTHTDEIVALKKVRMD--KEKD----GVPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGIPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQVDLIVQLLGTPSENIWPGFSQLP 268          

BLAST of EY659176 vs. ExPASy Swiss-Prot
Match: CDK11_DICDI (PITSVRE serine/threonine protein-kinase cdk11 OS=Dictyostelium discoideum GN=cdk11 PE=3 SV=1)

HSP 1 Score: 278.1 bits (710), Expect = 5.292e-74
Identity = 136/247 (55.06%), Postives = 185/247 (74.90%), Query Frame = 2

Query:   80 CRSVFEFEKLNKISEGTYGIVYRARDKKSGEIVALKKVKMNVGRKEDCLEYGFPISSLREINILLSFDHPSIVNVKEVVMDDH-DSVYMVMEYMEHDLKWLMESMKQPFSTSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNQGVLKICDFGMSRQYGSPLKPYTSLVVTLWYRAPELLLGAKKYSTAVDMWXSGCIMAELLAKNPCLVGTTEVDQMDRIFKTLSTSTETIGPGFLELPGAK 817
            CRSV  F+KL  I+EG +G+VY A+DK++ EIVALKK+KM   R+      G PI+S+REI +L+   H +IV +KE+V+  + +S++M ME+++HDL+ LME +K+PF  SE+K L+ QLL GV Y+HDNWV+HRDLKT+NLL  N+GVLKI DFG++R+YGSPLKP +  VVTLWYRAPELLL  + Y+ A+D+W  GCI AE+++K   L G++E+DQMD+IFK   T TE   P F +LP AK
Sbjct:   46 CRSVDCFKKLYTINEGAFGVVYCAQDKETEEIVALKKIKMERERE------GIPITSVREIKVLMELKHDNIVQIKEIVLGKNINSIFMAMEFIDHDLRGLMEVIKKPFLPSEIKTLIQQLLNGVSYMHDNWVIHRDLKTANLLYTNKGVLKIADFGLAREYGSPLKPLSKGVVTLWYRAPELLLDTEIYTPAIDIWSVGCIFAEIISKEVLLQGSSEIDQMDKIFKLFGTPTEKSWPAFFKLPLAK 286          

BLAST of EY659176 vs. ExPASy Swiss-Prot
Match: YP62_CAEEL (Putative serine/threonine-protein kinase B0495.2 OS=Caenorhabditis elegans GN=B0495.2 PE=2 SV=1)

HSP 1 Score: 276.174 bits (705), Expect = 2.011e-73
Identity = 134/256 (52.34%), Postives = 192/256 (75.00%), Query Frame = 2

Query:   71 LHGCRSVFEFEKLNKISEGTYGIVYRARDKKSGEIVALKKVKMNVGRKEDCLEYGFPISSLREINILLSF-DHPSIVNVKEVVMDDH-DSVYMVMEYMEHDLKWLMESMKQP---FSTSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNQGVLKICDFGMSRQYGSPLKPYTSLVVTLWYRAPELLLGAKKYSTAVDMWXSGCIMAELLAKNPCLVGTTEVDQMDRIFKTLSTSTETIGPGFLELPGAKAI 823
            L GCR++ E+E +N++ EGT+G+VYR +DK++ EIVALK++KM   ++      GFPI++LREIN+LL   +HP+IVNVKE+++  + D +YM ME++EHD+K L+++M +    FS  E K L+ QLL G++++H  W+LHRDLKTSNLL++++G+LKI DFG++R+YG PLK +TS+VVTLWYR+PELLLG + YST VDMW  GCIMAE +   P   G  E++Q+ +IF  + T TE+I PG  EL G KA+
Sbjct:  347 LMGCRNIDEYECVNRVDEGTFGVVYRGKDKRTDEIVALKRLKMEKEKE------GFPITALREINMLLKAGNHPNIVNVKEILLGSNMDKIYMAMEFVEHDMKSLLDTMSRRNKRFSIGEQKTLLQQLLSGIEHMHKLWILHRDLKTSNLLMSHKGILKIADFGLAREYGDPLKKFTSIVVTLWYRSPELLLGTRLYSTPVDMWSVGCIMAEFILLKPLFPGRGELEQIKKIFMEMGTPTESIWPGVTELDGWKAL 596          

BLAST of EY659176 vs. ExPASy Swiss-Prot
Match: CDK10_DICDI (Probable cyclin-dependent kinase 10 OS=Dictyostelium discoideum GN=cdk10 PE=2 SV=1)

HSP 1 Score: 264.233 bits (674), Expect = 7.908e-70
Identity = 131/248 (52.82%), Postives = 172/248 (69.35%), Query Frame = 2

Query:   83 RSVFEFEKLNKISEGTYGIVYRARDKKSGEIVALKKVKMNVGRKEDCLEYGFPISSLREINILLSFDHPSIVNVKEVVMDDH-DSVYMVMEYMEHDLKWLMESMKQPFSTSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNQGVLKICDFGMSRQYGSPLKPYTSLVVTLWYRAPELLLGAKKYSTAVDMWXSGCIMAELLAKNPCLVGTTEVDQMDRIFKTLSTSTETIGPGFLELPGAKAI 823
            RSV  FEKL+ I EGTYGIV + RDK++G IVALKKVK+    K+     G P++SLREI IL    HP+IV++ EVV+    D +Y+V EY+EHD+  L++++ +PF  SE+KC +LQLL  V+YLH +W++HRDLK SNLL  N G LK+ DFG++R++G P++  T  +VTLWYR+PELLLG +KYSTAVD+W  G I  ELL   P + G  EVDQ+ RIF  L    E I PGF  LP  K +
Sbjct:    2 RSVLSFEKLDSIGEGTYGIVSKGRDKETGRIVALKKVKIGQQDKD-----GIPLTSLREIQILKEIKHPNIVSLLEVVIGSTGDKIYLVFEYLEHDVASLIDNINKPFKLSEIKCFLLQLLRAVEYLHSHWIIHRDLKCSNLLYGNNGNLKLADFGLARKFGYPIESITPCMVTLWYRSPELLLGCQKYSTAVDLWSIGSIFGELLIGRPLITGNNEVDQIMRIFNLLGEPNEQIWPGFSSLPNFKRL 244          

BLAST of EY659176 vs. ExPASy Swiss-Prot
Match: PPK23_SCHPO (Serine/threonine-protein kinase ppk23 OS=Schizosaccharomyces pombe GN=ppk23 PE=2 SV=1)

HSP 1 Score: 241.121 bits (614), Expect = 7.169e-63
Identity = 126/252 (50.00%), Postives = 162/252 (64.29%), Query Frame = 2

Query:   71 LHGCRSVFEFEKLNKISEGTYGIVYRARDKKSGEIVALKKVKMNVGRKEDCLEYGFPISSLREINILLSFDHPSIVNVKEVVMD-DHDSVYMVMEYMEHDLKWLMESMKQPFSTSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNQGVLKICDFGMSRQYGSPLKPYTSLVVTLWYRAPELLLGAKKYSTAVDMWXSGCIMAELLAKNPCLVGTTEVDQMDRIFKTLSTSTETIGPGFLELPGAKAI 823
            L  C S+ ++E L KI EG+YGIVYR  DK +  +VALKK+K       D    GFPI+SLREI  L S  H +IV +++VV+  D   VY+VME+MEHDLK L+++M + F  SEVK LMLQLL    ++H +W LHRDLK SNLL+NN G +K+ DFG++R    P    T LVVTLWYRAPELLLGA  Y   +DMW  GCI AE++ + P   G +E+DQ+ +IF  L   T    P +  LP A  I
Sbjct:   65 LKSCNSIDDYEILEKIEEGSYGIVYRGLDKSTNTLVALKKIKF------DPNGIGFPITSLREIESLSSIRHDNIVELEKVVVGKDLKDVYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAATAFMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSLTRLVVTLWYRAPELLLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQLYKIFNLLGYPTREEWPQYFLLPYANKI 310          

BLAST of EY659176 vs. ExPASy Swiss-Prot
Match: BUR1_ASPFU (Serine/threonine-protein kinase bur1 OS=Aspergillus fumigatus GN=bur1 PE=3 SV=1)

HSP 1 Score: 238.424 bits (607), Expect = 4.647e-62
Identity = 125/283 (44.17%), Postives = 179/283 (63.25%), Query Frame = 2

Query:   38 AVVSVQRSMN---MLHGCRSVFEFEKLNKISEGTYGIVYRARDKKSGEIVALKKVKMNVGRKEDCLEYGFPISSLREINILLSFDHPSIVNVKEVVMD-------DHDSVYMVMEYMEHDLKWLMESMKQPFSTSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNQGVLKICDFGMSRQYGSP-----------LKPYTSLVVTLWYRAPELLLGAKKYSTAVDMWXSGCIMAELLAKNPCLVGTTEVDQMDRIFKTLSTSTETIGPGFLELPGAKAI 823
            A+ S++R  +      GC S+ +FE L K+ EGT+G VY+AR KK G IVALKK+ M+   ++D    GFPI++LREI +L    H +I+ +KE+ ++          S+YMV  YMEHDL  L+E+    F+  ++KC MLQLLEG+KYLH N +LHRD+K +NLL++N GVL+I DFG++R Y  P            + YT+LVVT WYR PELLL  ++Y+TA+DMW  GC+  E+    P L G+++++Q   IF  + T TE   PG+  LPG + +
Sbjct:    2 AIASLERDDHGNPRFRGCTSIRDFEFLGKLGEGTFGEVYKARSKKDGSIVALKKILMH--NEKD----GFPITALREIKLLKMLSHRNILQLKEMAVERSKGDGRKKPSMYMVTPYMEHDLSGLLENPAVNFTEPQIKCYMLQLLEGLKYLHGNRILHRDMKAANLLISNNGVLQIADFGLARPYDEPPPEPGKGGGEAKRDYTTLVVTRWYRPPELLLQLRRYTTAIDMWGVGCVFGEMFKGKPILAGSSDLNQTQLIFNLVGTPTEENMPGWSSLPGCEGV 278          

BLAST of EY659176 vs. ExPASy Swiss-Prot
Match: BUR1_EMENI (Serine/threonine-protein kinase bur1 OS=Emericella nidulans GN=ptkA PE=2 SV=1)

HSP 1 Score: 237.269 bits (604), Expect = 1.035e-61
Identity = 119/267 (44.57%), Postives = 172/267 (64.42%), Query Frame = 2

Query:   77 GCRSVFEFEKLNKISEGTYGIVYRARDKKSGEIVALKKVKMNVGRKEDCLEYGFPISSLREINILLSFDHPSIVNVKEVVMD-------DHDSVYMVMEYMEHDLKWLMESMKQPFSTSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNQGVLKICDFGMSRQY-----------GSPLKPYTSLVVTLWYRAPELLLGAKKYSTAVDMWXSGCIMAELLAKNPCLVGTTEVDQMDRIFKTLSTSTETIGPGFLELPGAKAI 823
            GC S+ EFE L K+ EGT+G VY+AR K+ G IVALKK+ M+  R       GFPI++LREI +L    H +I+ ++E+ ++          S+YMV  YMEHDL  L+E+ +  FS +++KC M+QLLEG+KYLH N +LHRD+K +NLL++NQG+L+I DFG++R +           G   + YT+LVVT WYR PELLL  ++Y++A+DMW  GC+  E+    P L G ++++Q   IF  + T TE   PG+  LPG + +
Sbjct:   18 GCTSIREFEFLGKLGEGTFGEVYKARAKRDGSIVALKKILMHNERD------GFPITALREIKLLKMLSHTNIMQLREMAVERSKGEGRKKPSMYMVFPYMEHDLSGLLENPEVHFSEAQIKCYMIQLLEGLKYLHGNCILHRDMKAANLLISNQGILQIADFGLARPFDEAPPQPGKGAGEAKRDYTTLVVTRWYRPPELLLQLRRYTSAIDMWGVGCVFGEMFKGKPILAGNSDLNQAQLIFSLVGTPTEENMPGWSSLPGCEGV 278          

BLAST of EY659176 vs. ExPASy Swiss-Prot
Match: BUR1_NEUCR (Serine/threonine-protein kinase bur-1 OS=Neurospora crassa GN=bur-1 PE=3 SV=1)

HSP 1 Score: 231.876 bits (590), Expect = 4.349e-60
Identity = 119/281 (42.35%), Postives = 175/281 (62.28%), Query Frame = 2

Query:   53 QRSMNMLHGCRSVFEFEKLNKISEGTYGIVYRARDKKSGEIVALKKVKMNVGRKEDCLEYGFPISSLREINILLSFDHPSIVNVKEVVMDD--------HDSVYMVMEYMEHDLKWLMESMKQPFSTSEVKCLMLQLLEGVKYLHDNWVLHRDLKTSNLLLNNQGVLKICDFGMSRQY-----------GSPLKPYTSLVVTLWYRAPELLLGAKKYSTAVDMWXSGCIMAELLAKNPCLVGTTEVDQMDRIFKTLSTSTETIGPGFLELPGAKAIFANNR 838
            QR      GC  + ++E L K+ EGT+G V+RAR +K+G +VALKK+ M+  R       GFPI++LREI +L    H +++ ++E+ ++            VYMV  YM+HDL  L+++    F+  +VKC +LQLLEG+KYLH N +LHRD+K +NLL+NN+GVL+I DFG++R Y           G   + YTSLVVT WYR PELL+  K+Y+TA+DMW  GC+ AE+L   P L G +++ Q++ ++    T +E   PG+  LPG +A  +  R
Sbjct:   11 QRDRGSFVGCSRIADYEVLGKLGEGTFGEVHRARSRKTGALVALKKIIMHNERD------GFPITALREIKLLKLLSHKNVLRLEEMAIEHPPRTDKRTRPIVYMVTPYMDHDLSGLLDNPSVRFTEPQVKCYLLQLLEGLKYLHANHILHRDMKAANLLINNKGVLQIADFGLARHYEGDIPQPGKGSGEGKRDYTSLVVTRWYRPPELLMHLKRYTTAIDMWGVGCVFAEMLEGKPVLQGESDLHQLELVWDLCGTPSEETMPGWRTLPGGQAFSSKPR 285