EY674986

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL3A_XENLA (Cullin-3-A OS=Xenopus laevis GN=cul3a PE=1 SV=1)

HSP 1 Score: 125.561 bits (314), Expect = 4.626e-28
Identity = 70/211 (33.18%), Postives = 122/211 (57.82%), Query Frame = 2

Query:    2 LLEKEQSGCRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGGSSSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKMGG 634
            ++E E SG   +L+  K EDL+ MY+L+ ++P GL+ +      ++  +G  LV +       +G     V     I+ +++L  ++  ++   F N  LF + +   FE F N     S S E L+ F D+ LKKG  + L+++ +E  L+K + L  ++ +KD+F  +Y++ LARRLL +++ +DD EK++++KLK +CG QFTSK+ G
Sbjct:  276 IVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSLYLREQGKALVSE-------EGEGKNPVD---YIQGLLDLKSRFDRFLQESFSNDRLFKQTIAGDFEYFLNL---NSRSPEYLSLFIDDKLKKGV-KGLTEQEVESILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEG 472          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL3_HUMAN (Cullin-3 OS=Homo sapiens GN=CUL3 PE=1 SV=2)

HSP 1 Score: 125.176 bits (313), Expect = 6.041e-28
Identity = 70/211 (33.18%), Postives = 121/211 (57.35%), Query Frame = 2

Query:    2 LLEKEQSGCRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGGSSSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKMGG 634
            ++E E SG   +L+  K EDL  MY+L+ ++P GL+ +      ++  +G  LV +       +G     V     I+ +++L  ++  ++   F N  LF + +   FE F N     S S E L+ F D+ LKKG  + L+++ +E  L+K + L  ++ +KD+F  +Y++ LARRLL +++ +DD EK++++KLK +CG QFTSK+ G
Sbjct:  276 IVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALVSE-------EGEGKNPVD---YIQGLLDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNL---NSRSPEYLSLFIDDKLKKGV-KGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEG 472          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL3_MOUSE (Cullin-3 OS=Mus musculus GN=Cul3 PE=1 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 1.030e-27
Identity = 70/211 (33.18%), Postives = 122/211 (57.82%), Query Frame = 2

Query:    2 LLEKEQSGCRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGGSSSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKMGG 634
            ++E E SG   +L+  K EDL+ MY+L+ ++P GL+ +      ++  +G  LV +       +G     V     I+ +++L  ++  ++   F N  LF + +   FE F N     S S E L+ F D+ LKKG  + L+++ +E  L+K + L  ++ +KD+F  +Y++ LARRLL +++ +DD EK++++KLK +CG QFTSK+ G
Sbjct:  276 IVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSE-------EGEGKNPVD---YIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNL---NSRSPEYLSLFIDDKLKKGV-KGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEG 472          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL4A_MOUSE (Cullin-4A OS=Mus musculus GN=Cul4a PE=2 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 1.346e-27
Identity = 71/206 (34.47%), Postives = 119/206 (57.77%), Query Frame = 2

Query:   17 QSGCRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGGSSSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKMGG 634
            Q G   LL E++V DL++MY+L+ ++  G   +   + ++I   GT +V   E             +++ +++ +++  DK    V  CF  +  F   +KE+FE F NK    +  +EL+A   D+ L+  GN++ +DE +E  L+K++ L  +I  KD+F  FY+K LA+RLL  ++A+ D EKS+L+KLK +CG  FTSK+ G
Sbjct:  304 QKGLEHLLDENRVPDLTQMYQLFSRVKGGQHALLQHWSEYIKTFGTTIVINPE-------------KDKDMVQDLLDFKDKVDHVVEVCFQRNERFINLMKESFETFINKRP--NKPAELIAKHVDSKLR-AGNKEATDEELERILDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEG 493          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL1_CAEEL (Cullin-1 OS=Caenorhabditis elegans GN=cul-1 PE=1 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 7.385e-26
Identity = 68/209 (32.54%), Postives = 121/209 (57.89%), Query Frame = 2

Query:   35 LLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEG-TVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGG---------SSSSELLATFCDNILKKGGNEKLSDEA-IEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKM 628
            LL + + +DLSRM++L  ++P GL+ +    + HI  EG   L + A +AAT+          ++ ++ ++E+H++Y   V   F N   F ++L +A   F N              + S+ELLA +CD +L+K  + K+ DEA +EE   K++ +  YI DKD+F++FY K  ++RL+ + +A+D+ E + +TKLK  CG ++T+++
Sbjct:  311 LLVDKRDDDLSRMFKLCDRVPNGLDELRKSLENHIAKEGHQALERVAMEAATDA---------KLYVKTLLEVHERYQSLVNRSFKNEPGFMQSLDKAATSFINNNAVTKRAPPQAQLTKSAELLARYCDQLLRK--SSKMPDEAELEELQTKIMVVFKYIDDKDVFSKFYTKMFSKRLISELSASDEAEANFITKLKSMCGYEYTARL 508          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL4_DICDI (Cullin-4 OS=Dictyostelium discoideum GN=culD PE=3 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 1.393e-24
Identity = 77/258 (29.84%), Postives = 135/258 (52.33%), Query Frame = 2

Query:   17 QSGCRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGGSSSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKMGGNGLQI*LWQEKNQTHL*RIPPQITKMPTLEKNFFIYCFPQRGFWPNL*NPPI 790
            + G  A++  D++EDL ++Y+L + + + ++ +   ++ +I   G  ++   E  AT             LI+ +++  D+    ++  F  + L   ALKE+FE F N     +  +EL+A F D+ LK GG +++S+E +E  L K + L  YI  KD+F  FY++ L++RLL D++ + D EKS+++KLK +CG  FT+K+      I L  +   +   R  P      ++E N ++      G WP    PPI
Sbjct:  314 EKGFNAMVNGDRLEDLGKLYQLLNSVGE-IKKIKESWQSYIKQTGIQMLNDKEKEAT-------------LIQDLLDYKDRLDRILSQSFSKNELLTYALKESFEYFINTKQ--NKPAELVARFIDSKLKVGG-KRMSEEELETVLNKSLILFRYIQGKDVFEAFYKQDLSKRLLLDKSTSIDAEKSMISKLKTECGTTFTAKLEEMFKDIELSNDIMNSF--RDSPMTQNFKSIEMNIYVL---TSGNWPI--QPPI 547          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL1_DROME (Cullin homolog 1 OS=Drosophila melanogaster GN=lin19 PE=1 SV=2)

HSP 1 Score: 114.005 bits (284), Expect = 1.393e-24
Identity = 71/205 (34.63%), Postives = 109/205 (53.17%), Query Frame = 2

Query:   35 LLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQA--EDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAV-----GGSSSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKM 628
            LL  D+ +DL RMY L     K L  + ++ + HI  +GT  + +    DAA +          +  ++ I+++H KY   V   F N   F  AL +A   F N  V       S S ELLA +CD +LKK       D+ +E+ L +V+ +  YI DKD+F ++Y K LA+RL+   +A+DD E  +++KLKQ CG ++T K+
Sbjct:  309 LLNADRNDDLKRMYSLVALSSKNLTDLKSILENHILHQGTEAIAKCCTTDAANDP---------KTYVQTILDVHKKYNALVLTAFNNDNGFVAALDKACGKFINSNVVTIANSASKSPELLAKYCDLLLKKSSKNP-EDKELEDNLNQVMVVFKYIEDKDVFQKYYSKMLAKRLVNHTSASDDAEAMMISKLKQTCGYEYTVKL 503          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL1_SCHPO (Cullin-1 OS=Schizosaccharomyces pombe GN=cul1 PE=1 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 5.292e-24
Identity = 66/202 (32.67%), Postives = 107/202 (52.97%), Query Frame = 2

Query:   35 LLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAV----GGSSSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKM 628
            +L ++  ED+ RMYRL  + P GL+P+   F++ +   G   V +       Q G    V  +  +  ++  +    E V   F   T F K+L  AF    N+ V      S S ELLA + D+IL+K  N+ +  + +E+ L  ++ +  Y+ DKD+F  FY K LA+RL+   + + D E S+L+KLK+ CG ++TSK+
Sbjct:  303 MLDQNCSEDIIRMYRLMSRTPNGLQPLRQTFEEFVKRSGFAAVAKI----VPQVGGEADVDPKEYMEMLLSTYKASKELVNTAFHGDTDFTKSLDTAFRELVNRNVVCQRSSSRSPELLAKYADSILRKS-NKNVDIDDVEDCLSSIIIIFRYVEDKDVFQNFYTKLLAKRLVNGTSNSQDAESSMLSKLKEVCGFEYTSKL 499          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL2_DICDI (Cullin-2 OS=Dictyostelium discoideum GN=culB PE=2 SV=1)

HSP 1 Score: 107.071 bits (266), Expect = 1.702e-22
Identity = 66/215 (30.70%), Postives = 114/215 (53.02%), Query Frame = 2

Query:    2 LLEKE----QSGCRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNK---AVGGSSSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSK 625
            L+EK     QS C   L+++K++++  MY+L  +I  GL PV    +++I   G   ++   D              ++ +  +++++ ++   +   F N   F   L  A     N+       + S ELLA +CD +LKKG N++  +  +EE L +++ L  Y+ DKD+F +FY K L+RRL+   + +DD EK ++T LKQ CG ++TSK
Sbjct:  261 LIEKHKELLQSECINYLKDEKLDEIYNMYKLLSRIEGGLAPVLETVQKYIQHVGIDAIKSIPDRNNPD--------PKIYVETLLKIYLQFSSIIKKSFNNDVSFITVLDLACHKIFNQNHITRNTTKSPELLAKYCDMLLKKG-NKQHEEIELEEKLGQIIVLFKYVDDKDVFQKFYSKMLSRRLINGTSVSDDIEKFMITGLKQACGFEYTSK 466          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL2_CAEEL (Cullin-2 OS=Caenorhabditis elegans GN=cul-2 PE=1 SV=2)

HSP 1 Score: 106.686 bits (265), Expect = 2.223e-22
Identity = 75/263 (28.52%), Postives = 125/263 (47.53%), Query Frame = 2

Query:    8 EKEQSGCRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGGSS---SSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKMGGNGLQI*LWQE------KNQTHL*RIPPQITKMPTLEKNFFIYCFPQRGFWP 769
            +K  + C  L+  ++ +DL  MYRL   I  GL  +   F++++  +G   V +           +G    Q  +  ++ +++K+ +  T  F++   F   L +A +   N    G S   +SE LA + D +LKK   + LS+  +E  L+  + +  YI DKD+F +FY K LA RL+   + + D E+ ++ KLKQ CG +FTSK+      I L QE      K+   +  + P +  +PT           Q G WP
Sbjct:  292 DKLHAVCHDLITNEENKDLRNMYRLLKPIQAGLSVMVKEFEEYVKKKGLEAVSRL----------TGENVPQQFVENVLRVYNKFNDMKTAVFMDDGEFSSGLDKALQGVVNSKEPGQSVPKASERLARYTDGLLKKS-TKGLSETDLEAKLDSAIVIFRYIEDKDIFQKFYSKMLANRLIASTSISMDAEELMINKLKQACGYEFTSKLSRMFTDIGLSQELSNNFDKHIADIKTVQPDVKFVPTQT------MILQAGSWP 537