EY674986

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL2_PONAB (Cullin-2 OS=Pongo abelii GN=CUL2 PE=2 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 8.449e-22
Identity = 61/206 (29.61%), Postives = 105/206 (50.97%), Query Frame = 2

Query:   26 CRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQV---LIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGGS--SSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKM 628
            C  ++R++K  D++ MY L   +  GL  +    + HI  EG                +S   QE +    +  ++E+H K+++ +         F  AL +A     N     S   + ELLA +CDN+LKK   + +++  +E+ L   + +  YI DKD+F +FY + LA+RL+   + + D E++++ KLKQ CG +FTSK+
Sbjct:  282 CHNIIRQEKKNDMANMYVLLRAVSTGLPHMIQELQNHIHDEGL-------------RATSNLTQENMPTLFVESVLEVHGKFVQLINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSA-KGMTENEVEDRLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKL 473          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL2_MOUSE (Cullin-2 OS=Mus musculus GN=Cul2 PE=1 SV=2)

HSP 1 Score: 104.76 bits (260), Expect = 8.449e-22
Identity = 60/208 (28.85%), Postives = 108/208 (51.92%), Query Frame = 2

Query:   20 SGCRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQV---LIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGGS--SSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKM 628
            S C +++++++  D++ MY L   +  GL  +    ++HI  EG                +S   QE +    +  ++E+H K+++ +         F  AL +A     N     S   + ELLA +CDN+LKK   + +++  +E+ L   + +  YI DKD+F +FY + LA+RL+   + + D E++++ KLKQ CG +FTSK+
Sbjct:  280 SECHSIIQQERKNDMANMYVLLRAVSSGLPHMIEELQKHIHDEGL-------------RATSNLTQEHMPTLFVESVLEVHGKFVQLINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSA-KGMTENEVEDKLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKL 473          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL2_HUMAN (Cullin-2 OS=Homo sapiens GN=CUL2 PE=1 SV=2)

HSP 1 Score: 104.76 bits (260), Expect = 8.449e-22
Identity = 61/206 (29.61%), Postives = 105/206 (50.97%), Query Frame = 2

Query:   26 CRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQV---LIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGGS--SSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKM 628
            C  ++R++K  D++ MY L   +  GL  +    + HI  EG                +S   QE +    +  ++E+H K+++ +         F  AL +A     N     S   + ELLA +CDN+LKK   + +++  +E+ L   + +  YI DKD+F +FY + LA+RL+   + + D E++++ KLKQ CG +FTSK+
Sbjct:  282 CHNIIRQEKKNDMANMYVLLRAVSTGLPHMIQELQNHIHDEGL-------------RATSNLTQENMPTLFVESVLEVHGKFVQLINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSA-KGMTENEVEDRLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKL 473          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL3_CAEEL (Cullin-3 OS=Caenorhabditis elegans GN=cul-3 PE=1 SV=2)

HSP 1 Score: 104.375 bits (259), Expect = 1.104e-21
Identity = 58/205 (28.29%), Postives = 109/205 (53.17%), Query Frame = 2

Query:   14 EQSGCRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGGSSSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKM 628
            +  G + +L   K+EDL+R++R++ +I   +       K  + A    L +   +   N+      V     + ++++L D +   +T  F +   F    +  FE F N       S E +A + D++L+ G  + +SD  ++  L+ V+ L  Y+ +KD+F +++++ LA+RLL D++ +DD EK++L KLK +CG QFT K+
Sbjct:  279 QNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVN---FVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDFETFLNS---NRQSPEFVALYMDDMLRSG-LKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKL 476          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL5_DICDI (Cullin-5 OS=Dictyostelium discoideum GN=culE PE=3 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 2.301e-19
Identity = 69/216 (31.94%), Postives = 114/216 (52.78%), Query Frame = 2

Query:   11 KEQSGCRAL--LREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGG-------SSSSELLATFCDNILKKGGNEKLSDEA-IEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKM 628
            KEQ   + L  L EDK  DL  MY L  ++   L P+ N+F   I +EG   ++     A  +         QVLI  +++++ ++   +  C+ N T F  A+ ++F I  N+           S+   +L+ FCD IL+KG +  +SDEA +E+ L + V L  Y+ DKD+F   Y+K L++RL+ D +A++D E  ++ KLK   G  + +K+
Sbjct:  265 KEQFASKFLDILIEDKSSDLVMMYSLLSRV-NHLTPLKNIFSDFIKSEGLKEIESNLKEAQEK--------PQVLISILLKIYSRFNIMIKECYGNDTDFTTAMDKSFSILVNENPASYDPKKKESNIPVVLSKFCDQILRKGPHH-ISDEAELEKKLTEAVCLFKYLPDKDIFMLNYQKMLSKRLVEDLSASEDAETLMINKLKNYQGFDYCTKL 470          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL3_SCHPO (Cullin-3 OS=Schizosaccharomyces pombe GN=cul3 PE=1 SV=2)

HSP 1 Score: 95.5153 bits (236), Expect = 5.126e-19
Identity = 68/260 (26.15%), Postives = 127/260 (48.85%), Query Frame = 2

Query:    2 LLEKEQSGCRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGG----SSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAVGGSSSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKMGGNGLQI*LWQEKNQTHL*RIPPQITKMPTLEKNFFIYCFPQRGFWP 769
            LLE + +G  +++     E L  +Y  + ++  G++ +     +++   G ++ +    A   +      SS A    + ++K++ L D+    ++           +L +AF  F +   G + + E ++ F D+ LKK   + + + +IE TL+  V L  +IS+KD+F ++Y+  LA+RLL +R+ + D E  ++++LKQ+ G  FT K+ G    + L QE  Q +      Q  K P L+ N  I       FWP
Sbjct:  299 LLENQSTGFFSMIDSSNFEGLQLVYESFSRVELGVKSLKKYLAKYVAHHGKLINETTSQALEGKMAVGRLSSNATMATLWVQKVLALWDRLNTIISTTMDADRSILNSLSDAFVTFVD---GYTRAPEYISLFIDDNLKKDARKAI-EGSIEATLQNSVTLFRFISEKDVFEKYYKTHLAKRLLNNRSISSDAELGMISRLKQEAGNVFTQKLEGMFNDMNLSQELLQEYKHNSALQSAK-PALDLNVSILA---STFWP 550          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL6_CAEEL (Cullin-6 OS=Caenorhabditis elegans GN=cul-6 PE=1 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 8.184e-17
Identity = 60/208 (28.85%), Postives = 105/208 (50.48%), Query Frame = 2

Query:   35 LLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQ-AEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAV---------GGSSSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKM 628
            LL   K E L+RMY L  ++  GLE +    ++ I  EG   +Q+ A+D+             +  I K++E+H+ Y   +   F  + LF ++L +A + F                + S++ LA +CD +LKK  N K+ DE     L+K + +L YIS+KD+F  +Y+   + R++ + +A+DD E+  +T L    G ++T  +
Sbjct:  265 LLEARKDEHLTRMYSLCRRVTHGLEDLRVYLEKRILKEGHETLQRLAKDSGLK-------TTPKEYITKLLEVHEIYFNLINKAFDRNALFMQSLDKASKDFIEANAVTMLAPEKHRSTRSADYLARYCDQLLKK--NSKVQDET---ALDKALTVLKYISEKDVFQLYYQNWFSERIINNSSASDDAEEKFITNLTATEGLEYTRNL 460          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL5_CAEEL (Cullin-5 OS=Caenorhabditis elegans GN=cul-5 PE=1 SV=2)

HSP 1 Score: 88.1965 bits (217), Expect = 8.184e-17
Identity = 60/211 (28.44%), Postives = 106/211 (50.24%), Query Frame = 2

Query:   26 CRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEG-TVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCNKAV---------------GGSSSSELLATFCDNILKKGG-NEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCG 607
            C  L+    VE L R+YRL  +   G++ V      HI  EG   +   AE+ +T+          +  +++++ + DK+   V   F +      A  +AF    N +                  S  +ELLA +CD +L+K   ++KL+ E I+E L +V+ +L Y+ +KD+F  F+R  L+RRL+ + +A+ + E+ ++TKL+ +CG
Sbjct:  264 CSKLIASKDVERLQRLYRLIRRTRSGIDTVLKCIDTHIRTEGLNDMRNNAENLSTDP---------ERYVQQLLLMFDKFSSLVREGFCDDARLLTARDKAFRAVVNDSSIFKTEMMNKKGRTLSVESKCAELLANYCDLLLRKTQLSKKLTSEEIDEKLNQVLLVLKYVENKDVFMRFHRAHLSRRLILEMSADQEKEEMMVTKLR-ECG 464          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL4_CAEEL (Cullin-4 OS=Caenorhabditis elegans GN=cul-4 PE=1 SV=3)

HSP 1 Score: 88.1965 bits (217), Expect = 8.184e-17
Identity = 54/203 (26.60%), Postives = 96/203 (47.29%), Query Frame = 2

Query:   35 LLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTVLVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHT---LFHKALKEAFEIFCNKAVGGSSSSELLATFCDNILKKGGNEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQQCGEQFTSKMGG 634
            L+  D + D+ RM+ L  +   G + V   F +++   G  L+    D              + L+ +++    K    +T  F +        + L +AFE F NK V    S+EL++     +L         D  +++ +++ + L  Y+  KD+F  +Y++ LA+RL  +R+A+ D EK +L KLK +CG  FT K+ G
Sbjct:  378 LIDSDNISDIGRMFNLCRQCVGGEDEVRTQFSKYLKKRGEKLIATCPD--------------EDLVSELLAFKKKVDFIMTGSFKSANDPVKMRQCLSDAFESFVNKQV--DRSAELISKHFHTLLHSSNKNVSDDTTLDQMVDEAIVLFRYLRGKDVFEAYYKRGLAKRLFLERSASVDAEKMVLCKLKTECGSAFTYKLEG 564          

BLAST of EY674986 vs. ExPASy Swiss-Prot
Match: CUL5_RABIT (Cullin-5 OS=Oryctolagus cuniculus GN=CUL5 PE=2 SV=3)

HSP 1 Score: 87.4261 bits (215), Expect = 1.396e-16
Identity = 56/211 (26.54%), Postives = 110/211 (52.13%), Query Frame = 2

Query:   26 CRALLREDKVEDLSRMYRLYHKIPKGLEPVANVFKQHITAEGTV-LVQQAEDAATNQGGSSGAVQEQVLIRKIIELHDKYMEYVTNCFINHTLFHKALKEAFEIFCN-------------KAVG-----GSSSSELLATFCDNILKKGG-NEKLSDEAIEETLEKVVKLLAYISDKDLFAEFYRKKLARRLLFDRNANDDHEKSILTKLKQ 598
            C+ +++ ++ E L  M+ L  K+P G+EP+    ++HI + G   +V  AE   T+          +  + +++ L +++ + V   F +   F  A  +A++   N             K VG      S   ELLA +CD +L+K   ++KL+ E IE  L++V+ +L Y+ +KD+F  +++  L RRL+ D +A+ + E++++  L++
Sbjct:  281 CQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDS---------EKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLRE 482