DR908378

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_CANTR (Lanosterol 14-alpha demethylase OS=Candida tropicalis GN=ERG11 PE=3 SV=2)

HSP 1 Score: 103.605 bits (257), Expect = 9.345e-22
Identity = 66/213 (30.99%), Postives = 106/213 (49.77%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKKHGKRVD---HDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAAGAFS---------------------YISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEFEL 567
            G   T+ E+  LLI  L  GQHTS+ TS W   +L +  +    + EE  +L+K+ G  ++   ++ L ++ ++   IKE LR+H PL  + R   +   V   +   Y IPKGH V  S  +A+     +++P+ ++P R+     +D  A A S                     Y+ FGGGRH C+GE FAY+Q+  I +  + NF++ L
Sbjct:  289 GVKMTDQEIANLLIGVLMGGQHTSASTSAWFLLHLAEQPQLQDDLYEELTNLLKEKGGDLNDLTYEDLQKLPLVNNTIKETLRMHMPLHSIFRKVMNPLRVPNTK---YVIPKGHYVLVSAGYAHTSDRWFEHPEHFNPRRW---ESDDTKASAVSFNSEDTVDYGFGKISKGVSSPYLPFGGGRHRCIGEQFAYVQLGTILTTYIYNFKWRL 495          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_CANAL (Lanosterol 14-alpha demethylase OS=Candida albicans GN=ERG11 PE=3 SV=2)

HSP 1 Score: 102.449 bits (254), Expect = 2.082e-21
Identity = 65/210 (30.95%), Postives = 99/210 (47.14%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKKHGKRVD---HDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDR------------FAPGREEDKAAGAFS------YISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEFEL 567
            G   T+ E+  LLI  L  GQHTS+ TS W   +L +       + +E   L+K+ G  ++   ++ L ++  +   IKE LR+H PL  + R   +   +       Y +PKGH V  SP +A+     + NP+ +DP R            F    E D   G  S      Y+ FGGGRH C+GE FAY+Q+  I +  + N  + +
Sbjct:  289 GVKMTDQEIANLLIGILMGGQHTSASTSAWFLLHLGEKPHLQDVIYQEVVELLKEKGGDLNDLTYEDLQKLPSVNNTIKETLRMHMPLHSIFRKVTNPLRIPETN---YIVPKGHYVLVSPGYAHTSERYFDNPEDFDPTRWDTAAAKANSVSFNSSDEVDYGFGKVSKGVSSPYLPFGGGRHRCIGEQFAYVQLGTILTTFVYNLRWTI 495          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_UNCNE (Eburicol 14-alpha-demethylase OS=Uncinula necator GN=CYP51 PE=2 SV=2)

HSP 1 Score: 98.2117 bits (243), Expect = 3.926e-20
Identity = 63/209 (30.14%), Postives = 104/209 (49.76%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLM--KKHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRF-----------APGREEDKAAGAFS------YISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEFELI 570
            G P  + E+  ++IA L AGQH+SS TS+W   +L    + +  + EEQ  +   +K    + ++ L+++ +    +KE LRLH P+  ++R   +   V    G +Y IP  H++ +SP   ++    + +P  +DP R+           A   + D   G  S      Y+ FG GRH C+GE FA LQ+  I + ++R F F  I
Sbjct:  290 GTPVPDREIAHMMIALLMAGQHSSSSTSSWIMLWLAARPDIMEELYEEQLRIFGSEKPFPPLQYEDLSKLQLHQNVLKEVLRLHAPIHSIMRKVKNPMIV---PGTKYVIPTSHVLISSPGCTSQDATFFPDPLKWDPHRWDIGSGKVLGNDAVDEKYDYGYGLTSTGASSPYLPFGAGRHRCIGEQFATLQLVTIMATMVRFFRFRNI 495          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP4CU_BLAGE (Cytochrome P450 4c21 OS=Blattella germanica GN=CYP4C21 PE=2 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 5.128e-20
Identity = 59/187 (31.55%), Postives = 94/187 (50.27%), Query Frame = 1

Query:   13 TESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKKHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEFELIS 573
            T++++   +   +F G  T S   TW    L  + E      +E + + +   +      L  M+ L R IKE+LRLHP +I  +R +H DF     E   Y IP G  +  S  F +R P I+ NP  ++PD F P R  ++    ++YI F  G   C+G+ FA L+ K + S+LLR++ F  ++
Sbjct:  295 TDTDILEEVHTFMFEGHDTVSAAMTWLLFELGHHPEIQEEAYKEVQDIFQGSDRVPTMADLNNMNYLERVIKESLRLHPSVIYFVREAHQDF-----ELGGYTIPAGTNIDFSVPFIHRNPEIFPNPRCFNPDNFLPDRVVNRHP--YAYIPFSAGPRNCIGQRFALLEEKVVLSYLLRHYRFRTVN 474          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP51_PENIT (Eburicol 14-alpha-demethylase OS=Penicillium italicum GN=CYP51 PE=3 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 2.814e-18
Identity = 60/200 (30.00%), Postives = 95/200 (47.50%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMKKHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAA-------GAFS------YISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEF 561
            G P  + E+  ++I  L AGQH+SS  S W    L    E    +  EQ   +      + +  + ++ +L   IKE LRLH  +  L+R   +   V    G ++ +P  H + +SP    R    +++P  +DP R+    E + ++       GA S      Y+ FG GRH C+GE FAYL ++ I + L+R F F
Sbjct:  286 GTPIPDKEIAHMMITLLMAGQHSSSAISCWILLRLASQPEMAEKLHAEQIKNLGADLPPLQYKDMDKLPLLRNVIKETLRLHSSIHTLMRKVKNPMPVP---GTDFVVPPSHTLLSSPGVTARDERHFRDPLRWDPHRWESRVEVEDSSDTVDYGYGAVSKGTRSPYLPFGAGRHRCIGEKFAYLNLEVIVATLVREFRF 482          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP4FC_HUMAN (Cytochrome P450 4F12 OS=Homo sapiens GN=CYP4F12 PE=1 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 1.396e-17
Identity = 53/188 (28.19%), Postives = 94/188 (50.00%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMK-KHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAIWSHLLRNFEF 561
            G+  ++ ++       +F G  T++   +W    L ++ EY    ++E + L+K +  K ++ D LA++  L  C+KE+LRLHPP   + R    D  +   +G+   IPKG          +  P ++ +P+ YDP RF P  E  K     ++I F  G   C+G+ FA  ++K + + +L +F F
Sbjct:  310 GKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLP--DGRV--IPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDP--ENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRF 491          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP4F3_HUMAN (Leukotriene-B(4) omega-hydroxylase 2 OS=Homo sapiens GN=CYP4F3 PE=2 SV=2)

HSP 1 Score: 89.7373 bits (221), Expect = 1.396e-17
Identity = 56/186 (30.11%), Postives = 96/186 (51.61%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMK-KHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAIWSHLLRNF 555
            G+  ++ ++       +F G  T++   +W   +L K+ EY    ++E + L+K +  K ++ D LA++  L  CIKE+LRLHPP+  + R    D  +   +G+   IPKG I   S    +  P ++ +P+ YDP RF P   ++++  AF  I F  G   C+G+ FA  ++K +    L  F
Sbjct:  310 GKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP--DGRV--IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAF--IPFSAGPRNCIGQAFAMAEMKVVLGLTLLRF 489          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP4F2_HUMAN (Leukotriene-B(4) omega-hydroxylase 1 OS=Homo sapiens GN=CYP4F2 PE=1 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 1.396e-17
Identity = 55/186 (29.57%), Postives = 95/186 (51.08%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMK-KHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAIWSHLLRNF 555
            G+  ++ ++       +F G  T++   +W   +L K+ EY    ++E + L+K +  K ++ D LA +  L  C+KE+LRLHPP+ ++ R    D  +   +G+   IPKG I   S    +  P ++ +P+ YDP RF P  E  K     ++I F  G   C+G+ FA  ++K + +  L  F
Sbjct:  310 GKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP--DGRV--IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDP--ENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRF 489          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP4F8_HUMAN (Cytochrome P450 4F8 OS=Homo sapiens GN=CYP4F8 PE=1 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 3.111e-17
Identity = 51/186 (27.42%), Postives = 92/186 (49.46%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMK-KHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAIWSHLLRNF 555
            G+  ++ ++       +F G  T++   +W    L ++ EY    ++E + L+K +  K ++ D LA++  L  C+KE+LRLHPP+    R    D  +         IPKG++   +    +  P ++ +P+ YDP RF P   + ++  AF  I F  G   C+G+ FA  ++K + +  L  F
Sbjct:  310 GKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSR----VIPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAF--IPFSAGPRNCIGQKFAMAEMKVVLALTLLRF 489          

BLAST of DR908378 vs. ExPASy Swiss-Prot
Match: CP4F6_RAT (Cytochrome P450 4F6 OS=Rattus norvegicus GN=Cyp4f6 PE=2 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 5.306e-17
Identity = 52/186 (27.96%), Postives = 96/186 (51.61%), Query Frame = 1

Query:    1 GRPTTESEVTGLLIAALFAGQHTSSITSTWTGAYLLKYKEYLSAVQEEQKHLMK-KHGKRVDHDILAEMDVLYRCIKEALRLHPPLIMLLRSSHSDFTVQTREGKEYDIPKGHIVGTSPAFANRLPHIYKNPDSYDPDRFAPGREEDKAAGAFSYISFGGGRHGCLGEPFAYLQIKAIWSHLLRNF 555
            G+  ++ ++       +F G  T++   +W    L ++ EY    ++E + L++ +  + ++ D LA++  L  CIKE+LRLHPP++++ R    D  +   +G+   IPKG+I   S    +  P ++ +P+ Y+P RF P  E  +     ++I F  G   C+G+ FA  +IK   +  L  F
Sbjct:  310 GKGLSDVDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVLLISRCCSQDIVLP--DGRV--IPKGNICVISIFGVHHNPSVWPDPEVYNPFRFDP--ENPQKRSPLAFIPFSAGPRNCIGQTFAMSEIKVALALTLLRF 489