CX069868

BLAST of CX069868 vs. ExPASy Swiss-Prot
Match: DHB5_MOUSE (Estradiol 17 beta-dehydrogenase 5 OS=Mus musculus GN=Akr1c6 PE=1 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 3.301e-26
Identity = 72/194 (37.11%), Postives = 106/194 (54.64%), Query Frame = -2

Query:  184 VHFPVATKHTGVGTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVS--CLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYR 753
            +HFP+A K    G      DE+G L  D  + +  TW AME     GL +SIG+SN++       L     K KPV NQ E HPY  +  L+ FC+   I + A++ LG      +W    S   LD+PVL  +A+KY RT A   LR+ +QR   V+ K+   +R++EN +VF+F+L+ EDM V+  +++  R
Sbjct:  116 IHFPMAMKP---GENYLPKDENGKLIYDA-VDICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILKKPGLKYKPVCNQVECHPYLNQGKLLDFCRSKDIVLVAYSALGSH-REKQWVDQSSPVLLDNPVLGSMAKKYNRTPALIALRYQLQRGVVVLAKSFSEKRIKENMQVFEFQLTSEDMKVLDDLNKNIR 304          

BLAST of CX069868 vs. ExPASy Swiss-Prot
Match: AKC1H_MOUSE (Aldo-keto reductase family 1 member C18 OS=Mus musculus GN=Akr1c18 PE=2 SV=2)

HSP 1 Score: 117.087 bits (292), Expect = 1.254e-25
Identity = 75/199 (37.69%), Postives = 106/199 (53.27%), Query Frame = -2

Query:  184 VHFPVATKHTGVGTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGA----VANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYR 753
            +HFPV+ K    G      DE G L  DT + L  TW AME     GL +SIG+SN+     ++ L +  L Y   KPV NQ E H Y  +  L+ +C+ + I + A+  LG        N +   T   LDDPVL  +A+KYKRT A   LR+ + R    + K+   ER+ EN +VFDF+L+ +DM ++  +DR  R
Sbjct:  116 IHFPVSLKP---GNELLPKDEHGNLIFDT-VDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY---KPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQRYKYCINED---TPVLLDDPVLCAMAKKYKRTPALIALRYQLDRGIVALAKSFNEERIRENMQVFDFQLASDDMKILDGLDRNLR 304          

BLAST of CX069868 vs. ExPASy Swiss-Prot
Match: GR_BACSU (Glyoxal reductase OS=Bacillus subtilis GN=yvgN PE=1 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 2.795e-25
Identity = 60/155 (38.71%), Postives = 91/155 (58.71%), Query Frame = -2

Query:  184 TWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYR 648
            TW A+E L   G +R+IG+SN+ +    + L  +++KP+VNQ E HP   +  L  +C+  GI + A +PL               LD+ VL  +AEK+ ++VAQ +LRW +Q     IPK+ K  R+ EN  +FDFELS+EDMD I ++++  R
Sbjct:  122 TWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKGQGIQLEAWSPLMQG----------QLLDNEVLTQIAEKHNKSVAQVILRWDLQHGVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDALNKDER 266          

BLAST of CX069868 vs. ExPASy Swiss-Prot
Match: XYL1_KLULA (NAD(P)H-dependent D-xylose reductase OS=Kluyveromyces lactis GN=XYL1 PE=3 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 3.650e-25
Identity = 73/236 (30.93%), Postives = 118/236 (50.00%), Query Frame = -2

Query:  172 WNSDH--GHVLEACKDSXXXXXXXXXXXXLVHFPVATKHTGVGT-------TDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGA----VANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFD-FELSKEDMDVIKSIDRKYRTNQP 837
            WNS H   +V  A + +             +HFP+A K             T    +  G +E +  + L  TW A+E LV  G ++S+GISN+   L +D L  +++KPV  Q E HPY  ++ L+K+ +  GI V A++  G      + N +   T +  +   +K +A K+K T  Q +LRW  Q   A+IPK+SK ERL +N ++ D   L+ +++  I  +++  R N P
Sbjct:   83 WNSFHHPDNVPRALERTLSDLQLDYVDIFYIHFPLAFKPVPFDEKYPPGFYTGKEDEAKGHIE-EEQVPLLDTWRALEKLVDQGKIKSLGISNFSGALIQDLLRGARIKPVALQIEHHPYLTQERLIKYVKNAGIQVVAYSSFGPVSFLELENKKALNTPTLFEHDTIKSIASKHKVTPQQVLLRWATQNGIAIIPKSSKKERLLDNLRINDALTLTDDELKQISGLNQNIRFNDP 317          

BLAST of CX069868 vs. ExPASy Swiss-Prot
Match: P100_LEIMA (Probable reductase OS=Leishmania major GN=P100/11E PE=2 SV=2)

HSP 1 Score: 114.39 bits (285), Expect = 8.131e-25
Identity = 74/220 (33.64%), Postives = 104/220 (47.27%), Query Frame = -2

Query:  184 WNSDHGH--VLEACKDSXXXXXXXXXXXXLVHFPVATKHTGVGTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYR 837
            WN++ G+   L A ++S            L+H+P              L ++G   +D+       W A E L     VR+IG+SN+ I    D LA   V P+VNQ E HP   +  L  FC    I V A +PLG              L +P+L  +  KY +T AQ +LRW IQ+N   IPK+   ER+EEN  +FDFEL  ED+  I +++   R
Sbjct:   81 WNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGK---------DILSKEGKKYLDS-------WRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLGQG----------KLLSNPILSAIGAKYNKTAAQVILRWNIQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDALNTNSR 274          

BLAST of CX069868 vs. ExPASy Swiss-Prot
Match: AKC1H_RAT (Aldo-keto reductase family 1 member C18 OS=Rattus norvegicus GN=Akr1c18 PE=1 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 8.131e-25
Identity = 72/196 (36.73%), Postives = 107/196 (54.59%), Query Frame = -2

Query:  184 VHFPVATKHTGVGTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVK--PVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGA----VANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYR 753
            +HFPV+ K    G      DE G L +DT + L  TW AME     GL +SIG+SN++       L    +K  PV NQ E H Y  +  L+ +C+ + I + A+  LG        N +   T   LDDP+L  +A+KYKRT A   LR+ ++R    + K+   ER+ EN +VFDF+L+ +DM+++ ++DR  R
Sbjct:  116 IHFPVSLKP---GDELLPQDEHGNLILDT-VDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQRYKYCINED---TPVLLDDPILCTMAKKYKRTPALIALRYQLERGIVTLVKSFNEERIRENLQVFDFQLASDDMEILDNLDRNLR 304          

BLAST of CX069868 vs. ExPASy Swiss-Prot
Match: XYL1_PICST (NAD(P)H-dependent D-xylose reductase OS=Pichia stipitis GN=XYL1 PE=3 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 1.062e-24
Identity = 79/247 (31.98%), Postives = 118/247 (47.77%), Query Frame = -2

Query:  145 WNSDH--GHVLEACKDSXXXXXXXXXXXXLVHFPVATKHTGV----------GTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGG----AVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYRTNQPARFWGIDLF 837
            WN+ H   +V +A   +            L+HFPV  K   +          G  D+   ED        + +  TW A+E LV  G +RSIG+SN+   L  D L  + +KP V Q E HPY Q+  L++F Q  GI VTA++  G      +       T    ++  +K +A K+ ++ AQ +LRW  QR  A+IPK++ + RL EN  V  F+L ++D   I  +D   R N P  +  I +F
Sbjct:   79 WNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLEEKYPPGFYCGKGDNFDYED--------VPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLRGATIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENETIKAIAAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAKLDINLRFNDPWDWDKIPIF 317          

BLAST of CX069868 vs. ExPASy Swiss-Prot
Match: XYL1_PACTA (NAD(P)H-dependent D-xylose reductase OS=Pachysolen tannophilus GN=XYL1 PE=1 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 1.062e-24
Identity = 76/230 (33.04%), Postives = 113/230 (49.13%), Query Frame = -2

Query:  172 WNSDHG--HVLEACKDSXXXXXXXXXXXXLVHFPVATKHTGVGTT--DSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGG----AVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYRTNQP 837
            WN+ H   +V +A   S            L+HFP++ K               DG   I   + +  TW AME+LV  GLV+SIG+SN    L  D +  +++KP   Q E HPY Q++ LV++ Q  GI VT ++  G      + N     T    ++  +  +A K+ +T  Q +LRW  QR  A+IPK++    L  N  V +F+L+KED + I  +DR  R N P
Sbjct:   79 WNNFHAKENVKKALMKSLSDFNLDYFDLYLMHFPISFKFVPFEEKYPPGFYCGDGDKFIYEDVPIIETWRAMENLVDEGLVKSIGVSNVSGGLLEDLIKAARIKPASLQIEHHPYLQQNKLVEYAQLKGIVVTGYSNFGPLSFLELGNETAKKTQPLYENKTITTIAAKHGKTPFQVLLRWVNQRGIAIIPKSTFPNTLAVNLHVDEFDLTKEDFEEIAKLDRHLRFNDP 308          

BLAST of CX069868 vs. ExPASy Swiss-Prot
Match: YOF5_CAEEL (Uncharacterized oxidoreductase ZK1290.5 OS=Caenorhabditis elegans GN=ZK1290.5 PE=2 SV=3)

HSP 1 Score: 112.079 bits (279), Expect = 4.035e-24
Identity = 61/157 (38.85%), Postives = 84/157 (53.50%), Query Frame = -2

Query:  184 ETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKVFDFELSKEDMDVIKSIDRKYR 654
            E TW  ME L     VRSIG+SNY I    + L ++ + P  NQ E HP+F +  L  +C + GI    + PL               L+D  L  +A KY+++ AQ  LRW IQ+N   +PK++   RL+EN  VFDFELS EDM+ + S   + R
Sbjct:  122 EKTWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHANQVELHPWFHQADLKNYCDELGILTMGYCPLAKG----------KYLEDETLCKIASKYQKSPAQICLRWSIQQNVPTVPKSTDCRRLKENTNVFDFELSAEDMNTLNSFSSQNR 268          

BLAST of CX069868 vs. ExPASy Swiss-Prot
Match: GRE3_YEAST (NADPH-dependent aldose reductase GRE3 OS=Saccharomyces cerevisiae GN=GRE3 PE=1 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 4.035e-24
Identity = 76/240 (31.67%), Postives = 122/240 (50.83%), Query Frame = -2

Query:  172 WNSDH--GHVLEACKDSXXXXXXXXXXXXLVHFPVATKHTGV------GTTDSALDEDGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGG--------AVANTEWFGTVSCLDDPVLKGLAEKYK-RTVAQTVLRWGIQRNTAVIPKTSKLERLEENFKV-FDFELSKEDMDVIKSIDRKYRTNQP 837
            WN+ H   HV  A K +             +HFP+A K+         G    A DE      +  + +  T+ A+E+ V  GL++SIG+SN+   L +D L   ++KPV  Q E HPY  ++ LV+FC+ H I V A++  G          +A T    T +  ++ V+K +++ +   T +Q +LRW  QR  AVIPK+SK ERL  N ++   F L+++++  I +++   R N P
Sbjct:   80 WNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKT----TPTLFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLGNLEIEKKFTLTEQELKDISALNANIRFNDP 315