DN621608

BLAST of DN621608 vs. ExPASy Swiss-Prot
Match: AAPK1_CAEEL (5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Caenorhabditis elegans GN=aak-1 PE=2 SV=2)

HSP 1 Score: 134.035 bits (336), Expect = 6.457e-31
Identity = 74/201 (36.82%), Postives = 120/201 (59.70%), Query Frame = 2

Query:   59 VEGWIVGQTLGEGAYGEVKLLLNRNTGSAVAMKIIDL--VKHPTACASVRKEALIHSRLSHSNVISYYGQRQDQNYVYMFLEYSSGGELFDRIEPDIGMSIAEAQKYFTELLAGVEYLHSMGIAHRDLKPENLLLDSCGTLKISDFGMATFFRVDGKERLLESKCGTLPYVAPEVL-EKIYSAEPADIWSCGIILVALLAG 652
            +  +++ +T+G+GA+G VK   +  TG  VA+KI++   +K        R E     +L+H ++   +      + +++ +E  SGGELF  I     + I E+++YF ++++GV Y H+  I HRDLKPENLLLD+   +KI+DFG++ +   DG   LL + CG+  Y APE++  K+Y     D+WSCG+IL A+L G
Sbjct:   21 IGNFVIKETIGKGAFGAVKRGTHIQTGYDVAIKILNRGRMKGLGTVNKTRNEIDNLQKLTHPHITRLFRVISTPSDIFLVMELVSGGELFSYITRKGALPIRESRRYFQQIISGVSYCHNHMIVHRDLKPENLLLDANKNIKIADFGLSNYM-TDGD--LLSTACGSPNYAAPELISNKLYVGPEVDLWSCGVILYAMLCG 218          

BLAST of DN621608 vs. ExPASy Swiss-Prot
Match: SIK1_RAT (Serine/threonine-protein kinase SIK1 OS=Rattus norvegicus GN=Sik1 PE=2 SV=1)

HSP 1 Score: 133.65 bits (335), Expect = 8.432e-31
Identity = 75/195 (38.46%), Postives = 115/195 (58.97%), Query Frame = 2

Query:   74 VGQTLGEGAYGEVKLLLNRNTGSAVAMKIIDLVKHPTA-CASVRKEALIHSRLSHSNVISYYGQRQDQNYVYMFLEYSSGGELFDRIEPDIGMSIAEAQKYFTELLAGVEYLHSMGIAHRDLKPENLLLDSCGTLKISDFGMATFFRVDGKERLLESKCGTLPYVAPEVLE-KIYSAEPADIWSCGIILVALLAG 652
            V +TLG+G +  VKL  +R T + VA+KIID  +  ++    + +E  +   L+H N+I  Y   + ++ +Y+  E++  GE+FD +  +  +S  EA+K F ++L+ VEY H+  I HRDLK ENLLLD    +K++DFG   F++       L + CG+ PY APEV E K Y     DIWS G++L  L+ G
Sbjct:   29 VERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPNIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHNHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYK---PGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCG 220          

BLAST of DN621608 vs. ExPASy Swiss-Prot
Match: NUAK1_MOUSE (NUAK family SNF1-like kinase 1 OS=Mus musculus GN=Nuak1 PE=2 SV=1)

HSP 1 Score: 133.65 bits (335), Expect = 8.432e-31
Identity = 76/215 (35.35%), Postives = 124/215 (57.67%), Query Frame = 2

Query:   17 NHCLHNLANHMTEFVEGWIVGQTLGEGAYGEVKLLLNRNTGSAVAMKII--DLVKHPTACASVRKEALIHSRLSHSNVISYYGQRQDQNYVYMFLEYSSGGELFDRIEPDIGMSIAEAQKYFTELLAGVEYLHSMGIAHRDLKPENLLLDSCGTLKISDFGMATFFRVDGKERLLESKCGTLPYVAPEVLE-KIYSAEPADIWSCGIILVALLAG 652
            +H  HNL  H  E  E      TLG+G YG+VK    R +G  VA+K I  D +K       +R+E  I S L+H ++IS Y   ++++ + + +EY+S GEL+D I     +S  E + +F ++++ V Y H  G+ HRDLK EN+LLD    +KI+DFG++  ++   K++ L++ CG+  Y +PE++  + Y     D W+ G++L  L+ G
Sbjct:   46 HHHKHNL-KHRYELQE------TLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQ---KDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLIYG 250          

BLAST of DN621608 vs. ExPASy Swiss-Prot
Match: CDR1_SCHPO (Mitosis inducer protein kinase cdr1 OS=Schizosaccharomyces pombe GN=cdr1 PE=1 SV=3)

HSP 1 Score: 133.65 bits (335), Expect = 8.432e-31
Identity = 79/196 (40.31%), Postives = 113/196 (57.65%), Query Frame = 2

Query:   68 WIVGQTLGEGAYGEVKLLLNRNTGSAVAMKIIDLVKHPTACASVRKEALIHSRLSHSNVISYYGQRQDQNYVYMFLEYSSGGELFDRIEPDIGMSIAEAQKYFTELLAGVEYLHSMGIAHRDLKPENLLLD-SCGTLKISDFGMATFFRVDGKERLLESKCGTLPYVAPEVL-EKIYSAEPADIWSCGIILVALLA 649
            W +G+TLG G+   V+L  +  TG   A+KII     P   AS+  E L+   L H N++  Y    D  ++Y+ LEY   GELF  I     +S  EA  Y +++L  V + H     HRDLK EN+L+  +   +KI+DFGMAT   V+  +  LE+ CG+L Y+APE++  K Y   PAD+WSCG+IL +LL+
Sbjct:   12 WRLGKTLGTGSTSCVRLAKHAKTGDLAAIKII-----PIRYASIGMEILMMRLLRHPNILRLYDVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREAAHYLSQILDAVAHCHRFRFRHRDLKLENILIKVNEQQIKIADFGMAT---VEPNDSCLENYCGSLHYLAPEIVSHKPYRGAPADVWSCGVILYSLLS 199          

BLAST of DN621608 vs. ExPASy Swiss-Prot
Match: AAPK2_PONAB (5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Pongo abelii GN=PRKAA2 PE=2 SV=1)

HSP 1 Score: 133.65 bits (335), Expect = 8.432e-31
Identity = 75/198 (37.88%), Postives = 116/198 (58.59%), Query Frame = 2

Query:   68 WIVGQTLGEGAYGEVKLLLNRNTGSAVAMKIIDL--VKHPTACASVRKEALIHSRLSHSNVISYYGQRQDQNYVYMFLEYSSGGELFDRIEPDIGMSIAEAQKYFTELLAGVEYLHSMGIAHRDLKPENLLLDSCGTLKISDFGMATFFRVDGKERLLESKCGTLPYVAPEVLE-KIYSAEPADIWSCGIILVALLAG 652
            +++G TLG G +G+VK+  ++ TG  VA+KI++   ++       +++E        H ++I  Y         +M +EY SGGELFD I     +   EA++ F ++L+ V+Y H   + HRDLKPEN+LLD+    KI+DFG++     DG+   L + CG+  Y APEV+  ++Y+    DIWSCG+IL ALL G
Sbjct:   16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNIMS-DGE--FLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCG 210          

BLAST of DN621608 vs. ExPASy Swiss-Prot
Match: AAPK2_PIG (5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Sus scrofa GN=PRKAA2 PE=2 SV=2)

HSP 1 Score: 133.65 bits (335), Expect = 8.432e-31
Identity = 75/198 (37.88%), Postives = 116/198 (58.59%), Query Frame = 2

Query:   68 WIVGQTLGEGAYGEVKLLLNRNTGSAVAMKIIDL--VKHPTACASVRKEALIHSRLSHSNVISYYGQRQDQNYVYMFLEYSSGGELFDRIEPDIGMSIAEAQKYFTELLAGVEYLHSMGIAHRDLKPENLLLDSCGTLKISDFGMATFFRVDGKERLLESKCGTLPYVAPEVLE-KIYSAEPADIWSCGIILVALLAG 652
            +++G TLG G +G+VK+  ++ TG  VA+KI++   ++       +++E        H ++I  Y         +M +EY SGGELFD I     +   EA++ F ++L+ V+Y H   + HRDLKPEN+LLD+    KI+DFG++     DG+   L + CG+  Y APEV+  ++Y+    DIWSCG+IL ALL G
Sbjct:   16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAQMNAKIADFGLSNMMS-DGE--FLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCG 210          

BLAST of DN621608 vs. ExPASy Swiss-Prot
Match: AAPK2_HUMAN (5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Homo sapiens GN=PRKAA2 PE=1 SV=2)

HSP 1 Score: 133.65 bits (335), Expect = 8.432e-31
Identity = 75/198 (37.88%), Postives = 116/198 (58.59%), Query Frame = 2

Query:   68 WIVGQTLGEGAYGEVKLLLNRNTGSAVAMKIIDL--VKHPTACASVRKEALIHSRLSHSNVISYYGQRQDQNYVYMFLEYSSGGELFDRIEPDIGMSIAEAQKYFTELLAGVEYLHSMGIAHRDLKPENLLLDSCGTLKISDFGMATFFRVDGKERLLESKCGTLPYVAPEVLE-KIYSAEPADIWSCGIILVALLAG 652
            +++G TLG G +G+VK+  ++ TG  VA+KI++   ++       +++E        H ++I  Y         +M +EY SGGELFD I     +   EA++ F ++L+ V+Y H   + HRDLKPEN+LLD+    KI+DFG++     DG+   L + CG+  Y APEV+  ++Y+    DIWSCG+IL ALL G
Sbjct:   16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS-DGE--FLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCG 210          

BLAST of DN621608 vs. ExPASy Swiss-Prot
Match: NUAK1_HUMAN (NUAK family SNF1-like kinase 1 OS=Homo sapiens GN=NUAK1 PE=1 SV=1)

HSP 1 Score: 133.265 bits (334), Expect = 1.101e-30
Identity = 76/215 (35.35%), Postives = 124/215 (57.67%), Query Frame = 2

Query:   17 NHCLHNLANHMTEFVEGWIVGQTLGEGAYGEVKLLLNRNTGSAVAMKII--DLVKHPTACASVRKEALIHSRLSHSNVISYYGQRQDQNYVYMFLEYSSGGELFDRIEPDIGMSIAEAQKYFTELLAGVEYLHSMGIAHRDLKPENLLLDSCGTLKISDFGMATFFRVDGKERLLESKCGTLPYVAPEVLE-KIYSAEPADIWSCGIILVALLAG 652
            +H  HNL  H  E  E      TLG+G YG+VK    R +G  VA+K I  D +K       +R+E  I S L+H ++IS Y   ++++ + + +EY+S GEL+D I     +S  E + +F ++++ V Y H  G+ HRDLK EN+LLD    +KI+DFG++  ++   K++ L++ CG+  Y +PE++  + Y     D W+ G++L  L+ G
Sbjct:   45 HHHKHNL-KHRYELQE------TLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQ---KDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYG 249          

BLAST of DN621608 vs. ExPASy Swiss-Prot
Match: MARK2_RAT (Serine/threonine-protein kinase MARK2 OS=Rattus norvegicus GN=Mark2 PE=1 SV=1)

HSP 1 Score: 132.109 bits (331), Expect = 2.453e-30
Identity = 72/193 (37.31%), Postives = 116/193 (60.10%), Query Frame = 2

Query:   80 QTLGEGAYGEVKLLLNRNTGSAVAMKIIDLVK-HPTACASVRKEALIHSRLSHSNVISYYGQRQDQNYVYMFLEYSSGGELFDRIEPDIGMSIAEAQKYFTELLAGVEYLHSMGIAHRDLKPENLLLDSCGTLKISDFGMATFFRVDGKERLLESKCGTLPYVAPEVLE-KIYSAEPADIWSCGIILVALLAG 652
            +T+G+G + +VKL  +  TG  VA+KIID  + + ++   + +E  I   L+H N++  +   + +  +Y+ +EY+SGGE+FD +     M   EA+  F ++++ V+Y H   I HRDLK ENLLLD+   +KI+DFG +  F    K   L++ CG+ PY APE+ + K Y     D+WS G+IL  L++G
Sbjct:   57 KTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSG 246          

BLAST of DN621608 vs. ExPASy Swiss-Prot
Match: MARK2_HUMAN (Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2)

HSP 1 Score: 132.109 bits (331), Expect = 2.453e-30
Identity = 72/193 (37.31%), Postives = 116/193 (60.10%), Query Frame = 2

Query:   80 QTLGEGAYGEVKLLLNRNTGSAVAMKIIDLVK-HPTACASVRKEALIHSRLSHSNVISYYGQRQDQNYVYMFLEYSSGGELFDRIEPDIGMSIAEAQKYFTELLAGVEYLHSMGIAHRDLKPENLLLDSCGTLKISDFGMATFFRVDGKERLLESKCGTLPYVAPEVLE-KIYSAEPADIWSCGIILVALLAG 652
            +T+G+G + +VKL  +  TG  VA+KIID  + + ++   + +E  I   L+H N++  +   + +  +Y+ +EY+SGGE+FD +     M   EA+  F ++++ V+Y H   I HRDLK ENLLLD+   +KI+DFG +  F    K   L++ CG+ PY APE+ + K Y     D+WS G+IL  L++G
Sbjct:   57 KTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK---LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSG 246