DN621132

BLAST of DN621132 vs. ExPASy Swiss-Prot
Match: MARK1_RAT (Serine/threonine-protein kinase MARK1 OS=Rattus norvegicus GN=Mark1 PE=1 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 1.297e-27
Identity = 65/134 (48.51%), Postives = 90/134 (67.16%), Query Frame = 2

Query:  302 GKYEVGKIIGCGAFAKVYHGRNVRTGQSVAIKAVSKQKILMGGLTAHVKREISIMSRLRHPNIVKLYEVLATKAKIYFVMEFAKGGELF-AKISKGRFSEQLSRRYFQQLISAVEYCHSRGVFHRDLKLENLLL 700
            G Y + K IG G FAKV   R+V TG+ VA+K + K ++    L   + RE+ IM  L HPNIVKL+EV+ T+  +Y VME+A GGE+F   ++ GR  E+ +R  F+Q++SAV+YCH + + HRDLK ENLLL
Sbjct:   58 GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQK-LFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLL 190          

BLAST of DN621132 vs. ExPASy Swiss-Prot
Match: MARK1_MOUSE (Serine/threonine-protein kinase MARK1 OS=Mus musculus GN=Mark1 PE=1 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 1.297e-27
Identity = 65/134 (48.51%), Postives = 90/134 (67.16%), Query Frame = 2

Query:  302 GKYEVGKIIGCGAFAKVYHGRNVRTGQSVAIKAVSKQKILMGGLTAHVKREISIMSRLRHPNIVKLYEVLATKAKIYFVMEFAKGGELF-AKISKGRFSEQLSRRYFQQLISAVEYCHSRGVFHRDLKLENLLL 700
            G Y + K IG G FAKV   R+V TG+ VA+K + K ++    L   + RE+ IM  L HPNIVKL+EV+ T+  +Y VME+A GGE+F   ++ GR  E+ +R  F+Q++SAV+YCH + + HRDLK ENLLL
Sbjct:   58 GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQK-LFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLL 190          

BLAST of DN621132 vs. ExPASy Swiss-Prot
Match: MARK1_HUMAN (Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1 PE=1 SV=2)

HSP 1 Score: 123.25 bits (308), Expect = 1.297e-27
Identity = 65/134 (48.51%), Postives = 90/134 (67.16%), Query Frame = 2

Query:  302 GKYEVGKIIGCGAFAKVYHGRNVRTGQSVAIKAVSKQKILMGGLTAHVKREISIMSRLRHPNIVKLYEVLATKAKIYFVMEFAKGGELF-AKISKGRFSEQLSRRYFQQLISAVEYCHSRGVFHRDLKLENLLL 700
            G Y + K IG G FAKV   R+V TG+ VA+K + K ++    L   + RE+ IM  L HPNIVKL+EV+ T+  +Y VME+A GGE+F   ++ GR  E+ +R  F+Q++SAV+YCH + + HRDLK ENLLL
Sbjct:   58 GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQK-LFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLL 190          

BLAST of DN621132 vs. ExPASy Swiss-Prot
Match: PAR1_CAEEL (Serine/threonine-protein kinase par-1 OS=Caenorhabditis elegans GN=par-1 PE=1 SV=1)

HSP 1 Score: 122.865 bits (307), Expect = 1.694e-27
Identity = 65/134 (48.51%), Postives = 91/134 (67.91%), Query Frame = 2

Query:  302 GKYEVGKIIGCGAFAKVYHGRNVRTGQSVAIKAVSKQKILMGGLTAHVKREISIMSRLRHPNIVKLYEVLATKAKIYFVMEFAKGGELF-AKISKGRFSEQLSRRYFQQLISAVEYCHSRGVFHRDLKLENLLL 700
            GKY++ K IG G FAKV   ++V TG  VAIK + K  +    L   + RE+ IM +L HPNIVKLY+V+ T+  +Y V+E+A GGE+F   ++ GR  E+ +R  F+Q++SAV+Y HS+ + HRDLK ENLLL
Sbjct:  168 GKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQK-LFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLL 300          

BLAST of DN621132 vs. ExPASy Swiss-Prot
Match: PAR1_CAEBR (Serine/threonine-protein kinase par-1 OS=Caenorhabditis briggsae GN=par-1 PE=3 SV=1)

HSP 1 Score: 122.865 bits (307), Expect = 1.694e-27
Identity = 65/134 (48.51%), Postives = 91/134 (67.91%), Query Frame = 2

Query:  302 GKYEVGKIIGCGAFAKVYHGRNVRTGQSVAIKAVSKQKILMGGLTAHVKREISIMSRLRHPNIVKLYEVLATKAKIYFVMEFAKGGELF-AKISKGRFSEQLSRRYFQQLISAVEYCHSRGVFHRDLKLENLLL 700
            GKY++ K IG G FAKV   ++V TG  VAIK + K  +    L   + RE+ IM +L HPNIVKLY+V+ T+  +Y V+E+A GGE+F   ++ GR  E+ +R  F+Q++SAV+Y HS+ + HRDLK ENLLL
Sbjct:  126 GKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPSSLQK-LFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLL 258          

BLAST of DN621132 vs. ExPASy Swiss-Prot
Match: MARK4_MOUSE (MAP/microtubule affinity-regulating kinase 4 OS=Mus musculus GN=Mark4 PE=1 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 2.212e-27
Identity = 71/166 (42.77%), Postives = 98/166 (59.04%), Query Frame = 2

Query:  206 RMSD*SCLNSCTTLTATMGDNTGDISREVNLFGKYEVGKIIGCGAFAKVYHGRNVRTGQSVAIKAVSKQKILMGGLTAHVKREISIMSRLRHPNIVKLYEVLATKAKIYFVMEFAKGGELFAK-ISKGRFSEQLSRRYFQQLISAVEYCHSRGVFHRDLKLENLLL 700
            R SD     S  +L A   ++      E    G Y + + IG G FAKV   R++ TG+ VAIK + K ++    L   + RE+ IM  L HPNIVKL+EV+ T+  +Y VME+A  GE+F   +S GR  E+ +R  F+Q++SAV YCH + + HRDLK ENLLL
Sbjct:   25 RSSDKGPSWSSRSLGARCRNSIASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLL 189          

BLAST of DN621132 vs. ExPASy Swiss-Prot
Match: MARK4_HUMAN (MAP/microtubule affinity-regulating kinase 4 OS=Homo sapiens GN=MARK4 PE=1 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 2.212e-27
Identity = 71/166 (42.77%), Postives = 98/166 (59.04%), Query Frame = 2

Query:  206 RMSD*SCLNSCTTLTATMGDNTGDISREVNLFGKYEVGKIIGCGAFAKVYHGRNVRTGQSVAIKAVSKQKILMGGLTAHVKREISIMSRLRHPNIVKLYEVLATKAKIYFVMEFAKGGELFAK-ISKGRFSEQLSRRYFQQLISAVEYCHSRGVFHRDLKLENLLL 700
            R SD     S  +L A   ++      E    G Y + + IG G FAKV   R++ TG+ VAIK + K ++    L   + RE+ IM  L HPNIVKL+EV+ T+  +Y VME+A  GE+F   +S GR  E+ +R  F+Q++SAV YCH + + HRDLK ENLLL
Sbjct:   25 RSSDKGPSWSSRSLGARCRNSIASCPEEQPHVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLL 189          

BLAST of DN621132 vs. ExPASy Swiss-Prot
Match: MARK3_RAT (MAP/microtubule affinity-regulating kinase 3 OS=Rattus norvegicus GN=Mark3 PE=2 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 2.212e-27
Identity = 64/134 (47.76%), Postives = 90/134 (67.16%), Query Frame = 2

Query:  302 GKYEVGKIIGCGAFAKVYHGRNVRTGQSVAIKAVSKQKILMGGLTAHVKREISIMSRLRHPNIVKLYEVLATKAKIYFVMEFAKGGELF-AKISKGRFSEQLSRRYFQQLISAVEYCHSRGVFHRDLKLENLLL 700
            G Y + K IG G FAKV   R++ TG+ VAIK + K ++    L   + RE+ IM  L HPNIVKL+EV+ T+  +Y +ME+A GGE+F   ++ GR  E+ +R  F+Q++SAV+YCH + + HRDLK ENLLL
Sbjct:   54 GNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLL 186          

BLAST of DN621132 vs. ExPASy Swiss-Prot
Match: MARK3_MOUSE (MAP/microtubule affinity-regulating kinase 3 OS=Mus musculus GN=Mark3 PE=1 SV=2)

HSP 1 Score: 122.479 bits (306), Expect = 2.212e-27
Identity = 64/134 (47.76%), Postives = 90/134 (67.16%), Query Frame = 2

Query:  302 GKYEVGKIIGCGAFAKVYHGRNVRTGQSVAIKAVSKQKILMGGLTAHVKREISIMSRLRHPNIVKLYEVLATKAKIYFVMEFAKGGELF-AKISKGRFSEQLSRRYFQQLISAVEYCHSRGVFHRDLKLENLLL 700
            G Y + K IG G FAKV   R++ TG+ VAIK + K ++    L   + RE+ IM  L HPNIVKL+EV+ T+  +Y +ME+A GGE+F   ++ GR  E+ +R  F+Q++SAV+YCH + + HRDLK ENLLL
Sbjct:   54 GNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKRIVHRDLKAENLLL 186          

BLAST of DN621132 vs. ExPASy Swiss-Prot
Match: CIPKM_ORYSJ (CBL-interacting protein kinase 22 OS=Oryza sativa subsp. japonica GN=CIPK22 PE=2 SV=1)

HSP 1 Score: 120.168 bits (300), Expect = 1.098e-26
Identity = 67/161 (41.61%), Postives = 97/161 (60.25%), Query Frame = 2

Query:  269 TGDISREVNLFGKYEVGKIIGCGAFAKVYHGRNVRTGQSVAIKAVSKQK-------------ILMGGLTAHVKREISIMSRLR-HPNIVKLYEVLATKAKIYFVMEFAKGGELFAKISK---GRFSEQLSRRYFQQLISAVEYCHSRGVFHRDLKLENLLL 700
            TGD   +  L G+YE+G+++G GA +KVY  R+ RTG  VA+KA+ KQ+                      V+RE++ + R+R HP++V L +VLAT++ +Y V+E A GG + + +     G + E  +RR F QL SAV + HS GVFHRD+K ENLLL
Sbjct:   13 TGDGYSKKVLQGRYELGRVLGQGASSKVYRARDARTGAHVAVKAIRKQQQPHHHPSCRSPEAAAAARRCVEVEREVAALRRVRGHPHVVALLDVLATRSTVYLVLELASGGSVLSALDSRGGGHYDEPAARRLFAQLASAVAHAHSLGVFHRDIKPENLLL 173