CX044145

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: MLTK_HUMAN (Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2)

HSP 1 Score: 165.622 bits (418), Expect = 2.674e-40
Identity = 90/250 (36.00%), Postives = 145/250 (58.00%), Query Frame = -3

Query:    1 GAFGKLYRGTY--NGEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHR---LGLIHRDLKSDNLLIFSDKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAVVNKGARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVVAM 735
            G+FG +YR  +    +EVA+K L + E + E              +L+ L H NI++F G   +P  + IVTEYA  GS+  ++   ++  + +   +  A DVA+GM Y+H    + +IHRDLKS N++I +D  +KI DFG +R    T  M+   GT+ WMAPE+IQ  P ++  D YS+G+VLWE++T  +PF+ +  +Q A+ VV K  R  IP+ C     E++ +CW+A+   RP   +++++
Sbjct:   25 GSFGSVYRAKWISQDKEVAVKKLLKIEKEAE--------------ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSL-VGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISI 259          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: M3K10_XENLA (Mitogen-activated protein kinase kinase kinase 10 OS=Xenopus laevis GN=map3k10 PE=2 SV=1)

HSP 1 Score: 165.236 bits (417), Expect = 3.493e-40
Identity = 96/260 (36.92%), Postives = 147/260 (56.54%), Query Frame = -3

Query:   25 KLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXML-ATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHR---LGLIHRDLKSDNLLIFS--------DKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAV-VNKGARPIIPNDCLPVLGEIMTRCWDANPDVRP 765
            +LN+ +    G FGK+Y+G +  EEVA+K +    +DP++              +   L HPNI+   G C KP   C+V EYA+GG + + L     + VP  + V  A+ +A+GM Y+H    + +IHRDL S N+LI          +K++ I DFG+AR   +T  M+   GTY WMAPE+I+   +++  DV+SFG++LWEL+TG +P++ + A+  A+ V +NK   P IP+ C      I+  CWD +P  RP
Sbjct:  117 ELNLDEIIGVGGFGKVYKGLWRDEEVAVKAVR---HDPDEDINVTAENVRQEAKIFCMLCHPNIIALTGVCLKPPHLCLVMEYARGGPLHRALA---GKKVPAHVLVNWAVQIAKGMTYLHNEAIVPIIHRDLGSSNILILEKAENDDLFNKTLNITDFGLAREWQKTTKMSA-AGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLP-IPSTCPEPFVRILEACWDPDPHSRP 368          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: M3K9_HUMAN (Mitogen-activated protein kinase kinase kinase 9 OS=Homo sapiens GN=MAP3K9 PE=1 SV=3)

HSP 1 Score: 164.851 bits (416), Expect = 4.561e-40
Identity = 98/266 (36.84%), Postives = 153/266 (57.52%), Query Frame = -3

Query:    7 KLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXML-ATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHR---LGLIHRDLKSDNLLIF--------SDKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAV-VNKGARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVV 765
            +L + +    G FGK+YR  + G+EVA+K      +DP++              L A LKHPNI+   G C K    C+V E+A+GG + + L+ ++   +P  + V  A+ +ARGM Y+H    + +IHRDLKS N+LI         S+K +KI DFG+AR   +T  M+   GTY WMAPE+I+   +++  DV+S+G++LWEL+TG +PF+ +  +  A+ V +NK A P IP+ C     ++M  CW+ +P  RP    ++
Sbjct:  143 ELTLEEIIGIGGFGKVYRAFWIGDEVAVKAAR---HDPDEDISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKR---IPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAREWHRTTKMSA-AGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALP-IPSTCPEPFAKLMEDCWNPDPHSRPSFTNIL 400          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: M3K9_MOUSE (Mitogen-activated protein kinase kinase kinase 9 OS=Mus musculus GN=Map3k9 PE=2 SV=1)

HSP 1 Score: 163.696 bits (413), Expect = 1.016e-39
Identity = 97/266 (36.47%), Postives = 153/266 (57.52%), Query Frame = -3

Query:    7 KLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXML-ATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHR---LGLIHRDLKSDNLLIF--------SDKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAV-VNKGARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVV 765
            +L + +    G FGK+YR  + G+EVA+K      +DP++              L A LKHPNI+   G C K    C+V E+A+GG + + L+ ++   +P  + V  A+ +ARGM Y+H    + +IHRDLKS N+LI         S+K ++I DFG+AR   +T  M+   GTY WMAPE+I+   +++  DV+S+G++LWEL+TG +PF+ +  +  A+ V +NK A P IP+ C     ++M  CW+ +P  RP    ++
Sbjct:  136 ELTLEEIIGIGGFGKVYRAFWAGDEVAVKAAR---HDPDEDISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKR---IPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILEITDFGLAREWHRTTKMSA-AGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALP-IPSTCPEPFAKLMEDCWNPDPHSRPSFTSIL 393          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: PYK2_DICDI (Dual specificity protein kinase pyk2 OS=Dictyostelium discoideum GN=splB PE=2 SV=2)

HSP 1 Score: 163.31 bits (412), Expect = 1.327e-39
Identity = 94/252 (37.30%), Postives = 144/252 (57.14%), Query Frame = -3

Query:    7 QGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLK----LAVKQALDVARGMAYVHRLGLIHRDLKSDNLLIFSDKSIKIADFGVARIEVQTEGMTPETGTY---RWMAPEMIQHRP-YTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAVVNKGARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVV 738
            +GAF +++ G + G  VAIK L+   ++ +               L    H NIV FIGAC KP   CI+TEY  GGS+   L    + +  +K    L +K A D+A G+ ++H + ++HRDL S N+L+    +IKI+DFG++R + +   MT   G     RW  PE+ ++   Y++KVDVY F +V+WE++TG +PF ++   QA+  V   G RP IP  C P L  ++T+CW+A+P+ RPP   +V
Sbjct:  861 EGAFSEVWEGWWKGIHVAIKKLKIIGDEEQ----FKERFIREVQNLKKGNHQNIVMFIGACYKPA--CIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVLKMATDMALGLLHLHSITIVHRDLTSQNILLDELGNIKISDFGLSREKSREGSMTMTNGGICNPRWRPPELTKNLGHYSEKVDVYCFSLVVWEILTGEIPFSDLDGSQASAQVAYAGLRPPIPEYCDPELKLLLTQCWEADPNDRPPFTYIV 1106          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: M3KSL_DROME (Mitogen-activated protein kinase kinase kinase OS=Drosophila melanogaster GN=slpr PE=1 SV=1)

HSP 1 Score: 163.31 bits (412), Expect = 1.327e-39
Identity = 94/264 (35.61%), Postives = 139/264 (52.65%), Query Frame = -3

Query:    7 KLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHR---LGLIHRDLKSDNLLIFS--------DKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAVVNKGARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVV 765
            +L++ +    G F K++RG Y+GEEVAIKI  +   D  +                 LKH NI    G C    + C+V EYA+GGS+ + L  +    +P  + V  A+ +ARGM Y+H    + +IHRDLKS N+LI+          K++KI DFG+AR    T+ M+   GTY WM PE+I    Y++  DV+S+G++LWEL+TG  P++    +  A+ V        IP  C    G +M  CW  +P  RP   E++
Sbjct:  141 ELDIKEVIGSGGFCKVHRGYYDGEEVAIKIAHQTGEDDMQRMRDNVLQEAKLFW--ALKHENIAALRGVCLNTKL-CLVMEYARGGSLNRILAGK----IPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTLKITDFGLAREMYNTQRMSA-AGTYAWMPPEVISVSTYSKFSDVWSYGVLLWELITGETPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEIL 396          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: M3K11_RAT (Mitogen-activated protein kinase kinase kinase 11 OS=Rattus norvegicus GN=Map3k11 PE=2 SV=1)

HSP 1 Score: 161.384 bits (407), Expect = 5.043e-39
Identity = 99/267 (37.08%), Postives = 149/267 (55.81%), Query Frame = -3

Query:    7 RKLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXML-ATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGL---IHRDLKSDNLLIFSD--------KSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAV-VNKGARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVV 768
            ++L + +    G FGK+YRG++ GE VA+K   +   DP++              L A L HPNI+     C +    C+V EYA GG + + L  R+   VP  + V  A+ +ARGM Y+H   L   IHRDLKS+N+L+           K++KI DFG+AR   +T  M+   GTY WMAPE+I+   +++  DV+SFG++LWEL+TG +P++ +  +  A+ V VNK   P IP+ C     ++M  CW  +P  RP  A ++
Sbjct:  116 QELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQ---DPDEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRR---VPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAREWHKTTQMSA-AGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLP-IPSTCPEPFAQLMADCWAQDPHRRPDFASIL 374          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: M3K11_MOUSE (Mitogen-activated protein kinase kinase kinase 11 OS=Mus musculus GN=Map3k11 PE=1 SV=1)

HSP 1 Score: 161.384 bits (407), Expect = 5.043e-39
Identity = 99/267 (37.08%), Postives = 149/267 (55.81%), Query Frame = -3

Query:    7 RKLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXML-ATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGL---IHRDLKSDNLLIFSD--------KSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAV-VNKGARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVV 768
            ++L + +    G FGK+YRG++ GE VA+K   +   DP++              L A L HPNI+     C +    C+V EYA GG + + L  R+   VP  + V  A+ +ARGM Y+H   L   IHRDLKS+N+L+           K++KI DFG+AR   +T  M+   GTY WMAPE+I+   +++  DV+SFG++LWEL+TG +P++ +  +  A+ V VNK   P IP+ C     ++M  CW  +P  RP  A ++
Sbjct:  116 QELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQ---DPDEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRR---VPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIEGDDMEHKTLKITDFGLAREWHKTTQMSA-AGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLP-IPSTCPEPFAQLMADCWAQDPHRRPDFASIL 374          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: M3K11_HUMAN (Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1)

HSP 1 Score: 161.384 bits (407), Expect = 5.043e-39
Identity = 99/267 (37.08%), Postives = 149/267 (55.81%), Query Frame = -3

Query:    7 RKLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXML-ATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGL---IHRDLKSDNLLIFSD--------KSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAV-VNKGARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVV 768
            ++L + +    G FGK+YRG++ GE VA+K   +   DP++              L A L HPNI+     C +    C+V EYA GG + + L  R+   VP  + V  A+ +ARGM Y+H   L   IHRDLKS+N+L+           K++KI DFG+AR   +T  M+   GTY WMAPE+I+   +++  DV+SFG++LWEL+TG +P++ +  +  A+ V VNK   P IP+ C     ++M  CW  +P  RP  A ++
Sbjct:  115 QELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQ---DPDEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRR---VPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQPIESDDMEHKTLKITDFGLAREWHKTTQMSA-AGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNKLTLP-IPSTCPEPFAQLMADCWAQDPHRRPDFASIL 373          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: YR818_MIMIV (Putative serine/threonine-protein kinase/receptor R818 OS=Acanthamoeba polyphaga mimivirus GN=MIMI_R818 PE=4 SV=1)

HSP 1 Score: 160.614 bits (405), Expect = 8.602e-39
Identity = 91/254 (35.83%), Postives = 141/254 (55.51%), Query Frame = -3

Query:    7 LNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLG--LIHRDLKSDNLLIFSDKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAVVNKGARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVV 762
            + +G     G++G +  G +    VA+K   + + D ++              L+ L+HP+I+  IGAC K    CIVTE+   GS+R  +   +      KL +K     A G+ Y+H     +IHRD+K  N+L+    ++KIADFG ARI+ +   MT   GT  W APE+I+   YT+KVDV+SFGIV+WE++T   PF     ++ +  ++ +GARP IP+DC     ++M +CW A PD RP + +V+
Sbjct: 1394 IQIGKQIGVGSYGIVNMGKWKNINVAVKKFVKQKIDEKQMLEFRAEIAF----LSQLRHPHIILMIGACLKRPNICIVTEFMGNGSLRNVI---KTTKPEWKLKIKMLYQTALGIGYLHNSDPIIIHRDIKPSNILVDDSMNVKIADFGFARIKEENSVMT-RCGTPCWTAPEIIRGEKYTEKVDVFSFGIVMWEVLTCKEPFSGCNFMKVSMDIL-EGARPQIPSDCPIDFTKLMKQCWHAKPDKRPSMEDVI 1638          

HSP 2 Score: 135.576 bits (340), Expect = 2.963e-31
Identity = 77/265 (29.06%), Postives = 138/265 (52.08%), Query Frame = -3

Query:    7 KLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPE--NDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGLIHRDLKSDNLLIFSDKSIKIADFGVARIEVQTEGMT----PETGTYRWMAPEMIQHRPYTQKV--DVYSFGIVLWELVTGMLPFQNMTAVQAAFAVVNKGARPIIPNDCLPVLG----EIMTRCWDANPDVRPPLAEVV 765
            +L+  ++   G  G++++  + G EVA+K L       D E+              + +L+HPN+V F+ A  +P   CIV E+   GS+   L       +P  L ++ A   A+GM ++H   ++HRDLKS NLL+ S  ++K++DFG+ +I+   +G +        + +W APE++  +     +  DVYSFGI++WEL+T + P+  ++    A AV+    RP I  + + ++     E++  CW  +  +RP   E++
Sbjct:  792 ELDFMESLGSGGSGEVFKAMWKGTEVAVKKLVNSNITKDAER------NFKQEIHRMTSLRHPNVVLFMAASTRPPNMCIVMEFMSLGSLYDLLGNELVTEIPPVLRIRIAYQAAKGMHFLHSSDIVHRDLKSLNLLLDSKWNVKVSDFGLTKIKDNNKGKSSTKEDSVCSIQWTAPEVLSEKQDIDYILADVYSFGIIMWELMTRLRPYIGLSPAAIAVAVIRDNLRPEIQEEDINLMSSDYVELVNICWHKDTMIRPSFLEIM 1050