CX044145

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: LIMK1_RAT (LIM domain kinase 1 OS=Rattus norvegicus GN=Limk1 PE=2 SV=1)

HSP 1 Score: 135.576 bits (340), Expect = 2.963e-31
Identity = 84/266 (31.58%), Postives = 134/266 (50.38%), Query Frame = -3

Query:   10 GDAFAQGAFGKLYRGTYN--GEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGLIHRDLKSDNLLIFSDKSIKIADFGVARIEVQTEGMTPE---------------TGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAVVNKG-ARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEV 753
            G+   +G FG+  + T+   GE + +K L R + + ++              +  L+HPN+++FIG   K      +TEY KGG++R  + K  +   P    V  A D+A GMAY+H + +IHRDL S N L+  ++++ +ADFG+AR+ +  +G + +                G   WMAPEMI  R Y +KVDV+SFGIVL E++  +    +       F +  +G      P +C P    I  RC D +P+ RP   ++
Sbjct:  342 GEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKV------MRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGII-KSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDEKGQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKL 600          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: SHKE_DICDI (Dual specificity protein kinase shkE OS=Dictyostelium discoideum GN=shkE PE=3 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 3.870e-31
Identity = 83/255 (32.55%), Postives = 135/255 (52.94%), Query Frame = -3

Query:   10 DAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLK---HPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRL-GLIHRDLKSDNLLIFSDKSIKIADFGVARIEVQTEGMTPETG---TYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAF-AVVNKGARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEV 750
            D    GA+GK+Y+ T  G++VA+K+       P+K              +  +K   HPN+V  +GAC KP    IV+E  +   + + +   +    PL   +K  LD A G+ ++H +  +IHRDLK  NL+I  DK++KI DFG +++      ++ + G   T  +MAPE++    + +K DVYSFG++L+E+ T    F   + +   + A+ NK  RP IP+     L  ++ +CWD +P+ RP   EV
Sbjct:  241 DLLGGGAYGKVYKATCRGKKVAVKV-------PKKQTLSESELKSFKNEVEIMKQIFHPNVVLCLGACTKPGKVMIVSELMQT-DLEKLIHSSEVEPPPLYERMKMCLDAALGINWLHGICNIIHRDLKLANLMISKDKTVKIGDFGFSQVIKTGTTLSDQKGPKGTALYMAPEVMMKHEFNEKADVYSFGLILYEMATCEELFPEYSEIDPFYDAICNKKLRPPIPDSFPKSLKTLIQKCWDHDPNKRPSFNEV 487          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: LIMK1_HUMAN (LIM domain kinase 1 OS=Homo sapiens GN=LIMK1 PE=1 SV=3)

HSP 1 Score: 135.191 bits (339), Expect = 3.870e-31
Identity = 89/266 (33.46%), Postives = 136/266 (51.13%), Query Frame = -3

Query:   10 GDAFAQGAFGKLYRGTYN--GEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGLIHRDLKSDNLLIFSDKSIKIADFGVARIEV----QTEGM----TPE-------TGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAVVNKG-ARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEV 753
            G+   +G FG+  + T+   GE + +K L R + + ++              +  L+HPN+++FIG   K      +TEY KGG++R  + K  +   P    V  A D+A GMAY+H + +IHRDL S N L+  +K++ +ADFG+AR+ V    Q EG+     P+        G   WMAPEMI  R Y +KVDV+SFGIVL E++  +    +       F +  +G      P +C P    I  RC D +P+ RP   ++
Sbjct:  342 GEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKV------MRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGII-KSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKL 600          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: MATK_RAT (Megakaryocyte-associated tyrosine-protein kinase OS=Rattus norvegicus GN=Matk PE=2 SV=1)

HSP 1 Score: 134.035 bits (336), Expect = 8.622e-31
Identity = 80/256 (31.25%), Postives = 136/256 (53.12%), Query Frame = -3

Query:    7 VRKLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGLIHRDLKSDNLLIFSDKSIKIADFGVARIEVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVT-GMLPFQNMTAVQAAFAVVNKGARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVV 771
            ++ L +G    +G FG + +G Y G++VA+K +        K             ++  L+H N+VR +G      ++ IV E+   G++  FL  R    V     ++ AL VA GM Y+    L+HRDL + N+L+  D   K++DFG+A+ E++ +G+       +W APE +++  ++ K DV+SFG++LWE+ + G  P+  M+  + + A V KG R   P+ C   +  +M  CW+A P  RPP  ++V
Sbjct:  191 LQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNI--------KCDVTAQAFLDETAVMTKLQHRNLVRLLGVILHHGLY-IVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKAELR-KGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEA-VEKGYRMEPPDSCPGPVHTLMGSCWEAEPSRRPPFRKIV 435          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: KINY_DICDI (Probable serine/threonine-protein kinase kinY OS=Dictyostelium discoideum GN=kinY PE=2 SV=1)

HSP 1 Score: 134.035 bits (336), Expect = 8.622e-31
Identity = 89/276 (32.25%), Postives = 142/276 (51.45%), Query Frame = -3

Query:    7 VRKLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMV--------------WCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGLIHRDLKSDNLLIFSDKSI---KIADFGVARI---EVQTEGMTPETGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNM-TAVQAAFAVVNKGARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVV 771
            ++ L +G++   GA+G +YRGT    +VAIK ++   N+  +             +L  ++HPNIV+FIG   +P+               W IVTEY  GG++ + + K   +  P++L +K +LD+A  MAY+H   +I RDLKS N+LI    S    K+ DFG ARI   + Q        GT   MAPE+I    Y + VD++SFG+VL E++      + +    Q+AF +    AR +IP+D   +  ++   C    P+ RP  + ++
Sbjct:   29 IKDLKVGESIGSGAYGIVYRGTLFNSDVAIKKIQ---NEKSEKNEFIKYLKREVAVLKNIQHPNIVQFIGVYYEPLASPSLVNRLLNSSSTW-IVTEYIGGGNLHERI-KDTKKDFPIELRIKLSLDIALAMAYLHSRDIIFRDLKSKNILIDDSSSPIRGKVCDFGFARILNKKQQGNRHLSICGTDSIMAPELILGMEYDESVDIFSFGVVLLEMILRKKVSKVLERGPQSAFEIDQDSARQLIPDDIPVLYSDLALDCIKYQPEERPNFSHII 299          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: RMIL_AVII1 (Serine/threonine-protein kinase-transforming protein Rmil OS=Avian retrovirus IC10 GN=V-RMIL PE=3 SV=1)

HSP 1 Score: 133.65 bits (335), Expect = 1.126e-30
Identity = 83/264 (31.44%), Postives = 141/264 (53.41%), Query Frame = -3

Query:    4 KLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGLIHRDLKSDNLLIFSDKSIKIADFGVARIEVQTEG---MTPETGTYRWMAPEMIQ---HRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAVVNKG----ARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVVA 765
            ++ +G     G+FG +Y+G ++G+ VA+K+L      P++              L   +H NI+ F+G   KP +  IVT++ +G S+   L   + +   +KL +  A   A+GM Y+H   +IHRDLKS+N+ +  D ++KI DFG+A ++ +  G       +G+  WMAPE+I+     PY+ + DVY+FGIVL+EL+TG LP+ N+        +V +G        + ++C   +  +M  C     D RP   +++A
Sbjct:   66 QITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKNEVGV----LRKTRHVNILLFMGYSTKPQL-AIVTQWCEGSSLYHHLHIIETKFEMIKL-IDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILA 322          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: RMIL_AVEVR (Serine/threonine-protein kinase-transforming protein Rmil OS=Avian rous-associated virus type 1 GN=V-RMIL PE=3 SV=1)

HSP 1 Score: 133.65 bits (335), Expect = 1.126e-30
Identity = 83/264 (31.44%), Postives = 141/264 (53.41%), Query Frame = -3

Query:    4 KLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGLIHRDLKSDNLLIFSDKSIKIADFGVARIEVQTEG---MTPETGTYRWMAPEMIQ---HRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAVVNKG----ARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVVA 765
            ++ +G     G+FG +Y+G ++G+ VA+K+L      P++              L   +H NI+ F+G   KP +  IVT++ +G S+   L   + +   +KL +  A   A+GM Y+H   +IHRDLKS+N+ +  D ++KI DFG+A ++ +  G       +G+  WMAPE+I+     PY+ + DVY+FGIVL+EL+TG LP+ N+        +V +G        + ++C   +  +M  C     D RP   +++A
Sbjct:   82 QITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKNEVGV----LRKTRHVNILLFMGYSTKPQL-AIVTQWCEGSSLYHHLHIIETKFEMIKL-IDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILA 338          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: LIMK1_MOUSE (LIM domain kinase 1 OS=Mus musculus GN=Limk1 PE=1 SV=1)

HSP 1 Score: 133.65 bits (335), Expect = 1.126e-30
Identity = 83/266 (31.20%), Postives = 133/266 (50.00%), Query Frame = -3

Query:   10 GDAFAQGAFGKLYRGTYN--GEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGLIHRDLKSDNLLIFSDKSIKIADFGVARIEVQTEGMTPE---------------TGTYRWMAPEMIQHRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAVVNKG-ARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEV 753
            G+   +G FG+  + T+   GE + +K L R + + ++              +  L+HPN+++FIG   K      +TEY KGG++R  + K  +   P    V  A D+A GMAY+H + +IHRDL S N L+  ++++ +ADFG+AR+ +  +  + +                G   WMAPEMI  R Y +KVDV+SFGIVL E++  +    +       F +  +G      P +C P    I  RC D +P+ RP   ++
Sbjct:  342 GEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKV------MRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGII-KNMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDEKNQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKL 600          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: BRAF1_MOUSE (B-Raf proto-oncogene serine/threonine-protein kinase OS=Mus musculus GN=Braf PE=1 SV=2)

HSP 1 Score: 133.65 bits (335), Expect = 1.126e-30
Identity = 83/264 (31.44%), Postives = 141/264 (53.41%), Query Frame = -3

Query:    4 KLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGLIHRDLKSDNLLIFSDKSIKIADFGVARIEVQTEG---MTPETGTYRWMAPEMIQ---HRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAVVNKG----ARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVVA 765
            ++ +G     G+FG +Y+G ++G+ VA+K+L      P++              L   +H NI+ F+G   KP +  IVT++ +G S+   L   + +   +KL +  A   A+GM Y+H   +IHRDLKS+N+ +  D ++KI DFG+A ++ +  G       +G+  WMAPE+I+     PY+ + DVY+FGIVL+EL+TG LP+ N+        +V +G        + ++C   +  +M  C     D RP   +++A
Sbjct:  493 QITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKNEVGV----LRKTRHVNILLFMGYSTKPQL-AIVTQWCEGSSLYHHLHIIETKFEMIKL-IDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILA 749          

BLAST of CX044145 vs. ExPASy Swiss-Prot
Match: BRAF1_HUMAN (B-Raf proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=BRAF PE=1 SV=4)

HSP 1 Score: 133.65 bits (335), Expect = 1.126e-30
Identity = 83/264 (31.44%), Postives = 141/264 (53.41%), Query Frame = -3

Query:    4 KLNMGDAFAQGAFGKLYRGTYNGEEVAIKILERPENDPEKAXXXXXXXXXXXXMLATLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTKRQNRSVPLKLAVKQALDVARGMAYVHRLGLIHRDLKSDNLLIFSDKSIKIADFGVARIEVQTEG---MTPETGTYRWMAPEMIQ---HRPYTQKVDVYSFGIVLWELVTGMLPFQNMTAVQAAFAVVNKG----ARPIIPNDCLPVLGEIMTRCWDANPDVRPPLAEVVA 765
            ++ +G     G+FG +Y+G ++G+ VA+K+L      P++              L   +H NI+ F+G   KP +  IVT++ +G S+   L   + +   +KL +  A   A+GM Y+H   +IHRDLKS+N+ +  D ++KI DFG+A ++ +  G       +G+  WMAPE+I+     PY+ + DVY+FGIVL+EL+TG LP+ N+        +V +G        + ++C   +  +M  C     D RP   +++A
Sbjct:  456 QITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKNEVGV----LRKTRHVNILLFMGYSTKPQL-AIVTQWCEGSSLYHHLHIIETKFEMIKL-IDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILA 712