CN185846

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: KIN28_YEAST (Serine/threonine-protein kinase KIN28 OS=Saccharomyces cerevisiae GN=KIN28 PE=1 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 3.254e-29
Identity = 71/187 (37.97%), Postives = 103/187 (55.08%), Query Frame = 3

Query:   93 KYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLARTT-SETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLGFLRSDNARRYVRMLPQFPKQNFSARFPNKSPGAVDLLEKMLVFDPNRRITVDEALCHPYLAPL 650
            K ++   LRG+ + H   +LHRDLKP+NLL + +  +K+ DFGLAR   +  + +T  VVTRWYRAPELL     YT+AIDIWSVG I  E+M R P  PG++ V Q+ +    +G+P +     + S      +++ P   +     RF   S  A+D +  ML  +P +R T  + L   Y   L
Sbjct:  107 KAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKEL 293          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: CDKL4_HUMAN (Cyclin-dependent kinase-like 4 OS=Homo sapiens GN=CDKL4 PE=2 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 3.254e-29
Identity = 65/188 (34.57%), Postives = 105/188 (55.85%), Query Frame = 3

Query:   75 ISAG*HKYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLGFLRSDNARRYVRMLPQFPKQNFSARFPNKSPGAVDLLEKMLVFDPNRRITVDEALCHPY 638
            ++ G  K  L+Q L+ L + H  N +HRD+KP N+L+     +KI DFG A+     D  T+YV TRWYRAPELL+  ++Y +++DIW++GC+  E++T QPL+PGK  V QL LI   +G          +S+     + +      +    +F +  P A++ ++  L  +P+ R+T  + L   Y
Sbjct:   98 VADGVIKSVLWQTLQALNFCHIHNCIHRDIKPENILITKQGIIKICDFGFAQILIPGDAYTDYVATRWYRAPELLVGDTQYGSSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHGISIPEPEDMETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSY 285          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: CDK9_XENTR (Cell division protein kinase 9 OS=Xenopus tropicalis GN=cdk9 PE=2 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 3.254e-29
Identity = 77/190 (40.53%), Postives = 107/190 (56.32%), Query Frame = 3

Query:   93 KYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLART-----TSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLGFLRSDNARRYVRM-LPQFPKQNFSARFPN--KSPGAVDLLEKMLVFDPNRRITVDEALCHPY 638
            K  +  LL GL Y+H   +LHRD+K +N+L+  +  LK+ DFGLAR       S+ +  T  VVT WYR PELLL   +Y   ID+W  GCI+ E+ TR P+  G    HQL LI++L GS   T   +   D    Y ++ LP+  K+    R     K   A+DL++K+LV DP +RI  D+AL H +
Sbjct:  131 KKVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNKYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLTLISQLCGS--ITPEVWPNVDKYELYQKLELPKGQKRKVKERLKAYVKDLYALDLIDKLLVLDPAQRIDSDDALNHDF 318          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: CDK4_MOUSE (Cell division protein kinase 4 OS=Mus musculus GN=Cdk4 PE=1 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 3.254e-29
Identity = 78/188 (41.49%), Postives = 105/188 (55.85%), Query Frame = 3

Query:   93 KYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLGFLRSDNARRYVRM-----LPQFPKQNFSARFPNKSPGAVDLLEKMLVFDPNRRITVDEALCHPYL 641
            K  + Q L GL ++H+  ++HRDLKP N+L+ +N  +K+ DFGLAR  S    +T  VVT WYRAPE+LL  S Y   +D+WSVGCI  E+  R+PLF G     QL  I +LIG P E        D+  R V +      P+ P+   S   P        LL +ML F+P++RI+   AL H YL
Sbjct:  118 KDLMRQFLSGLDFLHANCIVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQ-STYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPE--------DDWPREVSLPRGAFAPRGPRPVQSV-VPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYL 295          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: BUR1_CANAL (Serine/threonine-protein kinase BUR1 OS=Candida albicans GN=CRK1 PE=3 SV=2)

HSP 1 Score: 128.642 bits (322), Expect = 3.254e-29
Identity = 75/204 (36.76%), Postives = 112/204 (54.90%), Query Frame = 3

Query:   72 EISAG*HKYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLARTTSET------------DFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLGFLRSDNARRYVRMLPQFPKQNFSARFPNKSP-GAVDLLEKMLVFDPNRRITVDEALCHPYLA 644
            ++  G  K  + QLL+G++YVH+   LHRD+K +N+L+  +  LKI DFGLAR                    T  VVTRWYR PE+LL   +YT A+D+W +GC+  E+ T +P+  GK   HQ +++ EL+GSP  T     +  N   Y   L    K++  A+F +  P  A+DLL  +L  DP +R+   +AL H + +
Sbjct:  150 KLELGQIKCIMQQLLKGIQYVHNQKFLHRDIKAANILIGQDGVLKIADFGLARIYHGNVPRLGMGPGGGEKAYTGLVVTRWYRPPEILLGERKYTTAVDLWGIGCVFAELFTGKPILVGKSDSHQAQIVFELVGSP-LTWTDAAKLPNKNEYSCGLA--CKRSLEAKFASIMPTEAIDLLSGLLTLDPFKRLNALDALNHKFFS 350          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: Y7597_DROME (Cell division cycle 2-like protein kinase CG7597 OS=Drosophila melanogaster GN=CG7597 PE=1 SV=1)

HSP 1 Score: 128.257 bits (321), Expect = 4.249e-29
Identity = 80/193 (41.45%), Postives = 106/193 (54.92%), Query Frame = 3

Query:  108 QLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLARTTSETDFMTEY---VVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLGFLRSDNARRYVRMLPQFP--KQNFSAR------FPNKSPGAVDLLEKMLVFDPNRRITVDEALCHPYLAPLH 653
            QLL GL Y H  N LHRD+K SN+L+N    +K+ DFGLAR  +  D    Y   V+T WYR PELLL    Y  +ID+WS GCILGE+  ++PLF     + QL  I+++ GSP                V  LP F   KQ  + R      F      A+DLL+KML  DP++RIT ++AL  P+L  ++
Sbjct:  919 QLLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSPVPA---------VWPNVIKLPLFHTLKQKKTHRRRLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRKIN 1102          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: SGG_DROME (Protein kinase shaggy OS=Drosophila melanogaster GN=sgg PE=1 SV=2)

HSP 1 Score: 128.257 bits (321), Expect = 4.249e-29
Identity = 68/188 (36.17%), Postives = 104/188 (55.32%), Query Frame = 3

Query:   93 KYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCD-LKIGDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLGFLRSDNARRYVRMLPQFPKQNFSARFPNKSP-GAVDLLEKMLVFDPNRRITVDEALCHPYLAPL 650
            + ++YQL R L Y+HS  + HRD+KP NLLL+     LK+ DFG A+     +    Y+ +R+YRAPEL+     YT  ID+WS GC+L E++  QP+FPG   V QL  + +++G+P       +R  N        PQ     +   F  ++P  A++L+  +L + P+ RIT  +A  HP+   L
Sbjct:  710 RLYMYQLFRSLAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQ---IREMNPNYTEFKFPQIKSHPWQKVFRIRTPTEAINLVSLLLEYTPSARITPLKACAHPFFDEL 894          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: CDK4_RAT (Cell division protein kinase 4 OS=Rattus norvegicus GN=Cdk4 PE=2 SV=1)

HSP 1 Score: 128.257 bits (321), Expect = 4.249e-29
Identity = 79/191 (41.36%), Postives = 104/191 (54.45%), Query Frame = 3

Query:   93 KYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLGFLRSDNARRYVRMLPQFPKQNFSAR--------FPNKSPGAVDLLEKMLVFDPNRRITVDEALCHPYL 641
            K  + Q L GL ++H+  ++HRDLKP N+L+ +N  +K+ DFGLAR  S    +T  VVT WYRAPE+LL  S Y   +D+WSVGCI  E+  R+PLF G     QL  I +LIG P E        D+  R V +    P+  FS R         P        LL +ML F+P +RI+   AL H YL
Sbjct:  118 KDLMRQFLSGLDFLHANCIVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQ-STYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPE--------DDWPREVSL----PRGAFSPRGPRPVQSVVPEMEESGAQLLLEMLTFNPLKRISAFRALQHSYL 295          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: CDKL2_MACFA (Cyclin-dependent kinase-like 2 OS=Macaca fascicularis GN=CDKL2 PE=2 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 5.550e-29
Identity = 64/181 (35.36%), Postives = 105/181 (58.01%), Query Frame = 3

Query:   99 FLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLARTTSET-DFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLGFLRSDNARRYVRMLPQFPKQNFSARFPNKSPGAVDLLEKMLVFDPNRRITVDEALCHPY 638
            +L+Q++ G+ + HS N++HRD+KP N+L++ +  +K+ DFG ART +   +  T+YV TRWYRAPELL+   +Y  A+D+W++GC++ E+   +PLFPG   + QL  I   +G+           +     VR+     ++    R+P  S   +DL +K L  DP++R    E L H +
Sbjct:  106 YLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFYKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCSELLHHDF 286          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: CDKL2_HUMAN (Cyclin-dependent kinase-like 2 OS=Homo sapiens GN=CDKL2 PE=2 SV=1)

HSP 1 Score: 127.872 bits (320), Expect = 5.550e-29
Identity = 64/181 (35.36%), Postives = 105/181 (58.01%), Query Frame = 3

Query:   99 FLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLARTTSET-DFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLGFLRSDNARRYVRMLPQFPKQNFSARFPNKSPGAVDLLEKMLVFDPNRRITVDEALCHPY 638
            +L+Q++ G+ + HS N++HRD+KP N+L++ +  +K+ DFG ART +   +  T+YV TRWYRAPELL+   +Y  A+D+W++GC++ E+   +PLFPG   + QL  I   +G+           +     VR+     ++    R+P  S   +DL +K L  DP++R    E L H +
Sbjct:  106 YLFQIINGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRLPEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDF 286