CN185846

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: CDK8_HUMAN (Cell division protein kinase 8 OS=Homo sapiens GN=CDK8 PE=1 SV=1)

HSP 1 Score: 108.227 bits (269), Expect = 4.551e-23
Identity = 73/215 (33.95%), Postives = 110/215 (51.16%), Query Frame = 3

Query:   72 EISAG*HKYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCD----LKIGDFGLARTTSET----DFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLF--------PGKDYVH-QLRLITELIGSPDETSLGFLRSDNARRYVRMLPQFPKQNFS----ARFPNK-----SPGAVDLLEKMLVFDPNRRITVDEALCHPY 638
            ++  G  K  LYQ+L G+ Y+H+  VLHRDLKP+N+L+         +KI D G AR  +        +   VVT WYRAPELLL    YT AIDIW++GCI  E++T +P+F            Y H QL  I  ++G P +     ++      +  ++  F +  ++     ++  K        A  LL+K+L  DP +RIT ++A+  PY
Sbjct:  122 QLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIK--KMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPY 334          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: PRP4B_DICDI (Serine/threonine-protein kinase prpf4B OS=Dictyostelium discoideum GN=prpf4B PE=3 SV=1)

HSP 1 Score: 107.457 bits (267), Expect = 7.762e-23
Identity = 73/216 (33.80%), Postives = 112/216 (51.85%), Query Frame = 3

Query:   93 KYFLYQLLRGLKYVHSANVLHRDLKPSNLLLN-ANCDLKIGDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLI--------------TELIGSPDETSLGFLRS--DNARRYVRMLPQ-------------FPKQ-NFSARFPNKSPGAVDLLEKMLVFDPNRRITVDEALCHPYLAP 647
            + +  QL   LK++ ++ +LH D+KP N+++N A   +KI DFG A    E++ +T Y+V+R+YRAPE++L   +Y  +ID+WSVGC L E  T + LFPGK     +RL               +E + +    +L F++   DN  + VR +P               PK  +   +   K     DL+EK  + DP +RIT  EAL H +L P
Sbjct:  597 RVYAKQLFLALKHIKNSKILHADIKPDNIVVNEAKNTIKIVDFGSAGEIHESE-ITPYLVSRFYRAPEIILG-HKYDYSIDVWSVGCCLAEFFTGKFLFPGKTNNDMIRLFMEYRGAFSKKMLKKSEFVSNHFNENLVFMKQEIDNIEKTVRKVPHDITKPTKDILQFLLPKNVSIPDQDMKKLIQLKDLIEKCTILDPEKRITPFEALNHEFLKP 810          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: DYRK4_HUMAN (Dual specificity tyrosine-phosphorylation-regulated kinase 4 OS=Homo sapiens GN=DYRK4 PE=1 SV=2)

HSP 1 Score: 107.457 bits (267), Expect = 7.762e-23
Identity = 70/222 (31.53%), Postives = 115/222 (51.80%), Query Frame = 3

Query:   54 KTANFYEISAG*HKYFLYQLLRGLKYVHSANVLHRDLKPSNLLL--NANCDLKIGDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLGFLRSDNARRYVRMLPQFPKQNFSARFPNKSPGAVDL--------------LEKMLVFDPNRRITVDEALCHPYLAPLHDINEEP 671
            K  NF   S    + F   +L+ L+ +    ++H DLKP N++L       +K+ DFG   +  E   +  Y+ +R+YR+PE++L    Y  AID+WS+GCI  E+ T  PLFPG++ V QL  I E++G P     GF+++ + R+       FPK   + R   + P + DL              L + LV++P+ R+T D+AL H ++    ++  +P
Sbjct:  195 KNNNFQGFSLSIVRRFTLSVLKCLQMLSVEKIIHCDLKPENIVLYQKGQASVKVIDFG--SSCYEHQKVYTYIQSRFYRSPEVILG-HPYDVAIDMWSLGCITAELYTGYPLFPGENEVEQLACIMEVLGLP---PAGFIQTASRRQTFFDSKGFPKNITNNRGKKRYPDSKDLTMVLKTYDTSFLDFLRRCLVWEPSLRMTPDQALKHAWIHQSRNLKPQP 410          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: PPK5_SCHPO (Serine/threonine-protein kinase ppk5 OS=Schizosaccharomyces pombe GN=ppk5 PE=1 SV=1)

HSP 1 Score: 107.071 bits (266), Expect = 1.014e-22
Identity = 73/197 (37.06%), Postives = 102/197 (51.78%), Query Frame = 3

Query:   93 KYFLYQLLRGLKYVHSANVLHRDLKPSNLLLN--ANCDLKIGDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSP-------DETSLGFLRSDNARRYV-----RMLPQFPKQNFSARFPNKSPGAVDLLEKMLVFDPNRRITVDEALCHPYL 641
            K F  Q L+ L+ +   N++H DLKP NLLL+      +K+ DFG +   +E  +   Y+ +R+YRAPE++L   EY   IDIWS GCIL E+ T  PLFPG +   QL  I E++G P          S  +  S+     +     R+L     + FS     K    +D L K L +DP  RITVD AL H ++
Sbjct:  622 KSFALQGLQALRLLQGQNIIHCDLKPENLLLSHPLKARIKLIDFGSSCFYNEKVYT--YLQSRFYRAPEIILGL-EYGKEIDIWSFGCILAELFTGVPLFPGGNETEQLGYIMEVLGPPPMALIRNSTRSKAYFDSEGKPHPITDSHNRLLVP-STRTFSQLLNTKQASFLDFLSKCLKWDPKDRITVDSALQHEFI 814          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: IME2_YEAST (Meiosis induction protein kinase IME2/SME1 OS=Saccharomyces cerevisiae GN=IME2 PE=1 SV=1)

HSP 1 Score: 107.071 bits (266), Expect = 1.014e-22
Identity = 71/216 (32.87%), Postives = 106/216 (49.07%), Query Frame = 3

Query:   93 KYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNA-----------------NCDLKIGDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLGFLRS------------DNARRYVRMLP-QFPKQNFSARFPNKSPGAV----DLLEKMLVFDPNRRITVDEALCHPY 638
            K  L Q+L GLK++H  N  HRDLKP N+L+                   N  +K+ DFGLAR     +  T YV TRWYR+PE+LL    Y+  +DIW+ GC+  E+   + LFPG + + Q+  I E++G+P + S  F+ +            D+A   V  L  + P    S+     S   +    ++++K L +DPN R T  E    P+
Sbjct:  171 KSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPIKRS-DFVNTNHITAPPPGGFWDDASNLVHKLNLKLPYVEGSSLDHLLSSSQLSDLSEVVKKCLRWDPNERATAQELCEMPF 385          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: DYRK3_MOUSE (Dual specificity tyrosine-phosphorylation-regulated kinase 3 OS=Mus musculus GN=Dyrk3 PE=1 SV=1)

HSP 1 Score: 107.071 bits (266), Expect = 1.014e-22
Identity = 70/212 (33.02%), Postives = 107/212 (50.47%), Query Frame = 3

Query:   99 FLYQLLRGLKYVHSANVLHRDLKPSNLLL--NANCDLKIGDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDETSLG-------FLRSDNARRYVRMLPQFPKQ-----NFSARFPNKSPGA----------------VDLLEKMLVFDPNRRITVDEALCHPYLA 644
            F   +L+ L  +H   ++H DLKP N+LL  +     K+ DFG   +  E   +  Y+ +R+YRAPE++L C  Y+  IDIWS GCIL E++T QPLFPG+D   QL  + EL+G P +  L        F+ S    RY  +  Q   +       S R   + P                  ++ L++ L +DP+ R+T  +AL HP+++
Sbjct:  314 FAQSILQSLDALHKNKIIHCDLKPENILLKHHGRSATKVIDFG--SSCFEYQKLYTYIQSRFYRAPEIILGC-RYSTPIDIWSFGCILAELLTGQPLFPGEDEGDQLACMIELLGMPPQKLLEQSKRAKYFINSKGLPRYCSVSTQTDGRVVLLGGRSRRGKKRGPPGSKDWATALKGCGDYLFIEFLKRCLQWDPSARLTPAQALRHPWIS 522          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: SSN3_MAGGR (Serine/threonine-protein kinase SSN3 OS=Magnaporthe grisea GN=SSN3 PE=3 SV=2)

HSP 1 Score: 106.686 bits (265), Expect = 1.324e-22
Identity = 56/150 (37.33%), Postives = 89/150 (59.33%), Query Frame = 3

Query:   93 KYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLAR-------TTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKD----------------YVHQLRLITELIGSPDETSLGFLRS 473
            K  ++QLL G +Y+H+  VLHRDLKP+N+++ ++ ++K+GD GLAR       T  + D   + VVT WYRAPELL+    YT A+D+W+VGCI  E+++ +P+F G++                  HQ++ I +++G P +     L S
Sbjct:  171 KSIMFQLLNGCQYLHTNWVLHRDLKPANIMVTSSGEVKVGDLGLARIFWKPVRTLMQGD---KVVVTIWYRAPELLMGSHHYTPAVDMWAVGCIFAELLSLRPIFKGEEAKMDNTKKGGSRDMPFQRHQMQKIVDIMGMPTKERWPLLTS 317          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: LKH1_SCHPO (Dual specificity protein kinase lkh1 OS=Schizosaccharomyces pombe GN=lkh1 PE=1 SV=3)

HSP 1 Score: 106.301 bits (264), Expect = 1.729e-22
Identity = 74/216 (34.26%), Postives = 108/216 (50.00%), Query Frame = 3

Query:  108 QLLRGLKYVHSANVLHRDLKPSNLLLNAN-------------------CDLKIGDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYVHQLRLITELIGSPDE--------TSLGFLRSDNARRYVRMLPQFPK---------QNFSARFPNKSPGA---VDLLEKMLVFDPNRRITVDEALCHPY 638
            QL + + ++HS  ++H DLKP N+LL +N                   C++++ DFG A  T E ++ +  V TR YRAPE++L    ++   D+WS+GCIL E+ T Q LF   +    L ++ +++G  D         TS  F +SD   RY   L   PK         Q     F   SP     +DLL+K+ V+DP RRIT  EAL HP+
Sbjct:  471 QLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGSA--TFEDEYHSSVVSTRHYRAPEIILGLG-WSYPCDVWSIGCILVELFTGQALFQTHEDSEHLCMMEKILGPFDRNMISRSSRTSQRFFKSDGKVRYP--LSNTPKKSINYLQSLQTLEQIFAVSSPEVALLLDLLKKVFVYDPKRRITAKEALWHPF 681          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: CDK8_XENTR (Cell division protein kinase 8 OS=Xenopus tropicalis GN=cdk8 PE=2 SV=1)

HSP 1 Score: 106.301 bits (264), Expect = 1.729e-22
Identity = 72/215 (33.49%), Postives = 110/215 (51.16%), Query Frame = 3

Query:   72 EISAG*HKYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCD----LKIGDFGLARTTSET----DFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLF--------PGKDYVH-QLRLITELIGSPDETSLGFLRSDNARRYVRMLPQFPKQNFS----ARFPNKSPGAVD-----LLEKMLVFDPNRRITVDEALCHPY 638
            ++  G  K  LYQ+L G+ Y+H+  VLHRDLKP+N+L+         +KI D G AR  +        +   VVT WYRAPELLL    YT AIDIW++GCI  E++T +P+F            Y H QL  I  ++G P +     ++      +  ++  F +  ++     ++  K     D     LL+K+L  DP +RI+ ++A+  PY
Sbjct:  122 QLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIK--KMPEHSTLIKDFRRNTYTNCSLIKYMEKHKVKPDSKTFHLLQKLLTMDPIKRISSEQAMQDPY 334          

BLAST of CN185846 vs. ExPASy Swiss-Prot
Match: SSN3_GIBMO (Serine/threonine-protein kinase SSN3 OS=Gibberella moniliformis GN=SSN3 PE=1 SV=1)

HSP 1 Score: 105.916 bits (263), Expect = 2.258e-22
Identity = 71/244 (29.10%), Postives = 116/244 (47.54%), Query Frame = 3

Query:   93 KYFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLARTTSETDFMT----EYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTRQPLFPGKDYV-----------HQLRLITELIGSPDE----------------TSLGFLRSDNARRYVRMLPQFPKQNFSARFP------------------NKSPGAV-----------DLLEKMLVFDPNRRITVDEALCHPYLA 644
            K  ++QLL G +Y+H   VLHRDLKP+N+++ ++ ++KIGD GLAR   +         + VVT WYRAPEL+L    YT AID+W+VGCI  E+++ +P+F G++             +Q++ I E++G P +                T    + S +   +    P     ++ +R P                    +PG              LL  +L +DP++R+T  +AL  P+ +
Sbjct:  151 KSIMFQLLNGCQYLHINWVLHRDLKPANIMVTSSGEVKIGDLGLARRFDKPLHSLFSGDKVVVTIWYRAPELILGSYHYTPAIDMWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFRRNQMQKIIEIMGVPTKDKWPLLSTMPEYNQLNTLANSMASSHHNHHSHHHPHHHHGHYGSRNPPPPGGSNLEKWYYSTINHTSAPGGTPPLASLGSEGYKLLAGLLEYDPSKRLTAAQALQSPFFS 394