EY666537

BLAST of EY666537 vs. ExPASy Swiss-Prot
Match: MLL1_HUMAN (Histone-lysine N-methyltransferase MLL OS=Homo sapiens GN=MLL PE=1 SV=5)

HSP 1 Score: 100.908 bits (250), Expect = 9.700e-21
Identity = 52/113 (46.02%), Postives = 74/113 (65.49%), Query Frame = 3

Query:  414 LSMADKYKHMKETFRKRLAFGKSGIHGFGIFAKHPHRAGDMVIEYTGELVRPSIADRREHFIYNSLVGAGTYMFQIDDERVIDATKAGSIAHLNYHSCEPNWYSRVISANGDQ 752
            L M  +++H+K+T ++ +   +S IHG G+F K    AG+MVIEY G ++R    D+RE + Y+S  G G YMF+IDD  V+DAT  G+ A    HSCEPN YSRVI+ +G +
Sbjct: 3814 LPMPMRFRHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKY-YDSK-GIGCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQK 3924          

BLAST of EY666537 vs. ExPASy Swiss-Prot
Match: SET1B_CHICK (Histone-lysine N-methyltransferase SETD1B OS=Gallus gallus GN=SETD1B PE=2 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 9.079e-19
Identity = 66/191 (34.55%), Postives = 96/191 (50.26%), Query Frame = 3

Query:  192 SGCARSEPYNYFGRRGRKEPEALAAASLKRLFVENQPYLVGGYCQNGLSGNTLPSIRVIGSKFSFSLHRDAPNFLSMAD----KYKHMKETFRKRLAFGKSGIHGFGIFAKHPHRAGDMVIEYTGELVRPSIADRREHFIYNSLVGAGTYMFQIDDERVIDATKAGSIAHLNYHSCEPNWYSRVISANGDQ 752
            +GCARSE Y    ++ +     L   +  R F E  P    G     +      S R  GS+      R   +F    D    K+  +K   +K+L F KS IH +G+FA  P  A +MVIEY G+ +R  IAD RE    +  +G+ +YMF++D + +IDATK G+ A    HSC PN Y++VI+    +
Sbjct: 1786 TGCARSEGYYKIDKKDK-----LKYLNNSRAFAEEPPADTQGM---SIPAQPHASTRA-GSERRSEQRRLLSSFTGSCDSDLLKFNQLKFR-KKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGS-SYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQK 1965          

BLAST of EY666537 vs. ExPASy Swiss-Prot
Match: SET1_USTMA (Histone-lysine N-methyltransferase, H3 lysine-4 specific OS=Ustilago maydis GN=SET1 PE=3 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 2.642e-18
Identity = 46/101 (45.54%), Postives = 66/101 (65.35%), Query Frame = 3

Query:  450 TFRKRLAFGKSGIHGFGIFAKHPHRAGDMVIEYTGELVRPSIADRREHFIYNSLVGAGTYMFQIDDERVIDATKAGSIAHLNYHSCEPNWYSRVISANGDQ 752
            T +K+L F KS IH +G++A     AGDMVIEY GE+VR  +AD RE   Y       TY+F++DD+ V+DAT  G+IA L  H C PN  +++++ NG++
Sbjct: 1324 TRKKQLKFAKSPIHDWGLYAMELIPAGDMVIEYVGEVVRQQVADEREK-QYERQGNFSTYLFRVDDDLVVDATHKGNIARLMNHCCTPNCNAKILTLNGEK 1423          

BLAST of EY666537 vs. ExPASy Swiss-Prot
Match: SET1_COCIM (Histone-lysine N-methyltransferase, H3 lysine-4 specific OS=Coccidioides immitis GN=SET1 PE=3 SV=1)

HSP 1 Score: 92.4337 bits (228), Expect = 3.450e-18
Identity = 77/245 (31.43%), Postives = 115/245 (46.94%), Query Frame = 3

Query:   78 LLSFCKKHKQPLNDRLAVDERLVQVTRRCCDYIPPSNPSGCARSEPYNYFGRRGRKEPEA---------LAAASLKRLF-VENQPYLVGG-----YCQNGLSGNTLPSIRVIGSKFSFSLHRDAP-----NFLSMADKYKHMKETFRKRLAFGKSGIHGFGIFAKHPHRAGDMVIEYTGELVRPSIADRREHFIYNSLVGAGTYMFQIDDERVIDATKAGSIAHLNYHSCEPNWYSRVISANGDQ 752
            L ++  KHK+        D   V    R   Y  P NPSG AR+E     GR+  +E E          +  A  +RL   +N P+              LS +T  S RV   +    ++         N  S   ++  +K+  +K + F +S IH +G++A+    A DM+IEY GE VR  +AD RE     S +G+ +Y+F+ID+  VIDATK G IA    HSC PN  +++I  +G +
Sbjct:  989 LAAWTWKHKEIKAINRGGDRGPVHSETRIDGYYVP-NPSGSARTE-----GRKRIRESEKSKYLPHRIKVQKAREERLAKAKNDPHAAAAEAARLLAAKSLSKSTSRSTRVNNRRLIADINAQKQALPMQNGDSDVLRFNQLKKR-KKPVRFARSAIHNWGLYAEENISANDMIIEYVGEKVRQQVADMRERRYLKSGIGS-SYLFRIDENTVIDATKRGGIARFINHSCTPNCTAKIIKVDGSK 1225          

BLAST of EY666537 vs. ExPASy Swiss-Prot
Match: SET1_NEUCR (Histone-lysine N-methyltransferase, H3 lysine-4 specific OS=Neurospora crassa GN=set-1 PE=3 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 5.885e-18
Identity = 71/220 (32.27%), Postives = 109/220 (49.55%), Query Frame = 3

Query:  171 YIPPSNPSGCARSE--------------PYNYFGRRGRKEPE----------ALAAASLKRLFVENQPYLVGGYCQNGLSGNTLPSIRVIGSKFSFSLHRDAPNFLSMAD--KYKHMKETFRKRLAFGKSGIHGFGIFAKHPHRAGDMVIEYTGELVRPSIADRREHFIYNSLVGAGTYMFQIDDERVIDATKAGSIAHLNYHSCEPNWYSRVISANGDQ 752
            Y+P  NP+GCAR+E              P++   ++ R+E E            AAA   RL  ++   LV         GN+  + RV   ++   ++    NF   +D  ++  +K+  +K + F +S IH +G++A       DM+IEY GE VR  IA+ RE     S +G+ +Y+F+IDD  VIDATK G IA    HSC PN  +++I   G +
Sbjct: 1063 YVP--NPTGCARTEGVKKILNSEKSKYLPHHIKVKKAREEREKNAKNGNTNSVAAAAEAARLAADS---LVA-------KGNSRAN-RVNNRRYVAEINDQRKNFGQDSDVLRFNQLKKR-KKPVKFARSAIHNWGLYAMENINKDDMIIEYVGEEVRQQIAELREARYLKSGIGS-SYLFRIDDNTVIDATKKGGIARFINHSCMPNCTAKIIKVEGSK 1267          

BLAST of EY666537 vs. ExPASy Swiss-Prot
Match: SET1_CHAGB (Histone-lysine N-methyltransferase, H3 lysine-4 specific OS=Chaetomium globosum GN=SET1 PE=3 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 7.686e-18
Identity = 72/220 (32.73%), Postives = 109/220 (49.55%), Query Frame = 3

Query:  171 YIPPSNPSGCARSE--------------PYNYFGRRGRKEPEA----------LAAASLKRLFVENQPYLVGGYCQNGLSGNTLPSIRVIGSKFSFSLHRDAPNFLSMAD--KYKHMKETFRKRLAFGKSGIHGFGIFAKHPHRAGDMVIEYTGELVRPSIADRREHFIYNSLVGAGTYMFQIDDERVIDATKAGSIAHLNYHSCEPNWYSRVISANGDQ 752
            Y+P  NP+GCAR+E              P++   ++ R+E +A          LAAA   RL  E+   LV         GN+  + R    +F   L+         +D  ++  +K+  +K + F +S IH +G++A       DM+IEY GE VR  IA+ RE+    S +G+ +Y+F+IDD  VIDATK G IA    HSC PN  +++I   G +
Sbjct:  826 YVP--NPTGCARAEGVKKILNSEKSKYLPHHIKVKKAREERQAQNGKNAKDSVLAAAEAARLAAES---LVA-------KGNSRAN-RANNRRFVADLNDQRKTLGQDSDVLRFNQLKKR-KKPVKFARSAIHNWGLYAMENIPKDDMIIEYVGEEVRQQIAELRENRYLKSGIGS-SYLFRIDDNTVIDATKKGGIARFINHSCMPNCTAKIIKVEGSK 1030          

BLAST of EY666537 vs. ExPASy Swiss-Prot
Match: SE1BA_DANRE (Histone-lysine N-methyltransferase SETD1B-A OS=Danio rerio GN=setd1ba PE=1 SV=2)

HSP 1 Score: 90.8929 bits (224), Expect = 1.004e-17
Identity = 62/189 (32.80%), Postives = 96/189 (50.79%), Query Frame = 3

Query:  192 SGCARSEPYNYFGRRGRKEPEALAAASLKRLFVENQPYLVGGYCQNGLSGNTLPSIRV-IGSKFSFSLHRDAPNFLSMADKYKHMKETFRKR-LAFGKSGIHGFGIFAKHPHRAGDMVIEYTGELVRPSIADRREHFIYNSLVGAGTYMFQIDDERVIDATKAGSIAHLNYHSCEPNWYSRVISANGDQ 752
            +GCARSE Y    ++ + +    +    +   V+ Q          G S    P +    GS+      R   +F   +D  K  +  FRK+ + F +S IH +G+FA  P  A +MVIEY G+ +R  IAD RE    +  +G+ +YMF++D + +IDATK G+ A    HSC PN Y++VI+    +
Sbjct: 1624 TGCARSEGYYKIDKKDKMKYLNSSRLQSEEPDVDTQ----------GKSIPAQPQVSTRAGSERRSEQRRLLSSFSCDSDLLKFNQLKFRKKKIRFCRSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGS-SYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQK 1801          

BLAST of EY666537 vs. ExPASy Swiss-Prot
Match: SET1B_XENTR (Histone-lysine N-methyltransferase SETD1B OS=Xenopus tropicalis GN=setd1b PE=2 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 1.311e-17
Identity = 65/191 (34.03%), Postives = 94/191 (49.21%), Query Frame = 3

Query:  192 SGCARSEPYNYFGRRGRKEPEALAAASLKRLFVENQPYLVGGYCQNGLSGNTLPSIRVIGSKFSFSLHRDAPNFLSMAD----KYKHMKETFRKRLAFGKSGIHGFGIFAKHPHRAGDMVIEYTGELVRPSIADRREHFIYNSLVGAGTYMFQIDDERVIDATKAGSIAHLNYHSCEPNWYSRVISANGDQ 752
            +GCARSE Y    ++ +     L      R   E  P    G     +      S R  GS+      R   +F    D    K+  +K   +K+L F KS IH +G+FA  P  A +MVIEY G+ +R  IAD RE    +  +G+ +YMF++D + +IDATK G+ A    HSC PN Y++VI+    +
Sbjct: 1734 TGCARSEGYYKIDKKDK-----LKYLINNRSLTEELPIDTQG---KSIPAQPQASTRA-GSERRSEQRRLLSSFTGSCDSDLLKFNQLKFR-KKKLRFCKSHIHDWGLFAMEPIIADEMVIEYVGQNIRQVIADMREKRYEDEGIGS-SYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQK 1913          

BLAST of EY666537 vs. ExPASy Swiss-Prot
Match: SET1B_MOUSE (Histone-lysine N-methyltransferase SETD1B OS=Mus musculus GN=Setd1b PE=2 SV=2)

HSP 1 Score: 89.3521 bits (220), Expect = 2.921e-17
Identity = 60/189 (31.75%), Postives = 95/189 (50.26%), Query Frame = 3

Query:  192 SGCARSEPYNYFGRRGRKEPEALAAASLKRLFVENQPYLVGG--YCQNGLSGNTLPSIRVIGSKFSFSLHRDAPNFLSMADKYKHMKETFRKRLAFGKSGIHGFGIFAKHPHRAGDMVIEYTGELVRPSIADRREHFIYNSLVGAGTYMFQIDDERVIDATKAGSIAHLNYHSCEPNWYSRVISANGDQ 752
            +GCARSE +    ++ +      + AS     ++ Q   +    +             R + S F+ S   D   F  +  K++      +K+L F KS IH +G+FA  P  A +MVIEY G+ +R  IAD RE    +  +G+ +YMF++D + +IDATK G+ A    HSC PN Y++VI+    +
Sbjct: 1763 TGCARSEGFYTIDKKDKLRYLNSSRASTDEPPMDTQGMSIPAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQL--KFR------KKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGS-SYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQK 1942          

BLAST of EY666537 vs. ExPASy Swiss-Prot
Match: SET1B_HUMAN (Histone-lysine N-methyltransferase SETD1B OS=Homo sapiens GN=SETD1B PE=1 SV=2)

HSP 1 Score: 88.9669 bits (219), Expect = 3.814e-17
Identity = 44/99 (44.44%), Postives = 64/99 (64.65%), Query Frame = 3

Query:  456 RKRLAFGKSGIHGFGIFAKHPHRAGDMVIEYTGELVRPSIADRREHFIYNSLVGAGTYMFQIDDERVIDATKAGSIAHLNYHSCEPNWYSRVISANGDQ 752
            +K+L F KS IH +G+FA  P  A +MVIEY G+ +R  IAD RE    +  +G+ +YMF++D + +IDATK G+ A    HSC PN Y++VI+    +
Sbjct: 1783 KKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGS-SYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQK 1880