CN188826

BLAST of CN188826 vs. ExPASy Swiss-Prot
Match: IDH_RICBR (Isocitrate dehydrogenase [NADP] OS=Rickettsia bellii (strain RML369-C) GN=icd PE=3 SV=1)

HSP 1 Score: 154.451 bits (389), Expect = 7.176e-37
Identity = 84/180 (46.67%), Postives = 119/180 (66.11%), Query Frame = -1

Query:  290 ESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEITYEEVVIDNCCMMLVKNPAAFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGEGGIALAEAVHGSAPDIAGKNLANPTALLLSSVTMLRHLELHDKADRIQNAILSTIAEGKYRTADL 829
            ES+K+I+R    ++  YAF YA  + R++V+ + K NIM+ +DG+F K   E+A++YP+I  E  +ID     L   P  FDV+V  NLYGDIISD+ A + G +GL  S NIGE   A+ EAVHGSAPDIAG+++ANP+ LL +++ ML H+   D A  I+NA   TI +G + TAD+
Sbjct:  141 ESVKLISRTGCEKIIRYAFEYAVKNNRKKVTCLSKDNIMKFSDGIFHKVFNEIAKEYPQINNEHYIIDIGTARLATKPEIFDVIVTSNLYGDIISDVAAEISGSVGLAGSANIGE-HYAMFEAVHGSAPDIAGQDIANPSGLLNAAIMMLVHIGQGDIATLIENAWKKTIEDGMH-TADI 318          

BLAST of CN188826 vs. ExPASy Swiss-Prot
Match: LYS12_YEAST (Homoisocitrate dehydrogenase, mitochondrial OS=Saccharomyces cerevisiae GN=LYS12 PE=1 SV=1)

HSP 1 Score: 154.066 bits (388), Expect = 9.373e-37
Identity = 83/207 (40.10%), Postives = 122/207 (58.94%), Query Frame = -1

Query:  239 VVESLKIITRQASLRVAEYAFHYA----KTHGRERVSAIHKANIMQKTDGLFLKCCREVAE----KYPEITYEEVVIDNCCMMLVKNPAAFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGEGGIALAEAVHGSAPDIAGKNLANPTALLLSSVTMLRHLELHDKADRIQNAILSTIAEGKYRTADLGGSSTTSDFTKAICDHL 835
            V ++ K I+  A+ R+A  A   A    +T G+  ++  HK+N++ ++DGLF + C+EV E    KY +I Y E ++D+    L + P  FDV+V PNLYGDI+SD  A L+G LG+ PS N+G   I + E  HGSAPDIAGK +ANP A + S+  ML  L  ++ A  I  A+ + + EG  +T DLGG ++T      +   L
Sbjct:  166 VADATKRISEIATRRIATIALDIALKRLQTRGQATLTVTHKSNVLSQSDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGP-EIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNEAAQDIYKAVDANLREGSIKTPDLGGKASTQQVVDDVLSRL 371          

BLAST of CN188826 vs. ExPASy Swiss-Prot
Match: LEU3_SULTO (3-isopropylmalate dehydrogenase OS=Sulfolobus tokodaii GN=leuB PE=1 SV=3)

HSP 1 Score: 154.066 bits (388), Expect = 9.373e-37
Identity = 91/207 (43.96%), Postives = 127/207 (61.35%), Query Frame = -1

Query:  239 GVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEITYEEVVIDNCCMMLVKNPAAFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGEGGIALAEAVHGSAPDIAGKNLANPTALLLSSVTMLRHL------ELHDKADR-IQNAILSTIAEGKYRTADLGGSSTTSDFTKAICDHL 838
            GV   +KIITR AS R+A+   ++A    R++V+ +HKAN+M+ TDGLF + CR V +   ++ Y E+ +D     LV+NP  FDV+V  N+YGDI+SD  + + G LG+ PS NIG+   AL E VHG+A DIAGKN+ NPTA LLS   M   +      + + KA R ++NAI     E K  T D+GG++TT D    I + L
Sbjct:  134 GVAVGMKIITRFASERIAKVGLNFALRR-RKKVTCVHKANVMRITDGLFAEACRSVLKG--KVEYSEMYVDAAAANLVRNPQMFDVIVTENVYGDILSDEASQIAGSLGIAPSANIGDKK-ALFEPVHGAAFDIAGKNIGNPTAFLLSVSMMYERMYELSNDDRYIKASRALENAIYLVYKERKALTPDVGGNATTDDLINEIYNKL 336          

BLAST of CN188826 vs. ExPASy Swiss-Prot
Match: IDH_RICFE (Isocitrate dehydrogenase [NADP] OS=Rickettsia felis GN=icd PE=3 SV=2)

HSP 1 Score: 153.68 bits (387), Expect = 1.224e-36
Identity = 84/187 (44.92%), Postives = 120/187 (64.17%), Query Frame = -1

Query:  269 ESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEITYEEVVIDNCCMMLVKNPAAFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGEGGIALAEAVHGSAPDIAGKNLANPTALLLSSVTMLRHLELHDKADRIQNAILSTIAEGKYRTADLGGSSTTS 829
            ES+K+I+     ++  YAF YA  + R++V+ + K NIM+ +DG+F K   E+A++YP+I  E  +ID     L   P  FDV+V  NLYGDIISD+ A + G +GL  S NIG+   A+ EAVHGSAPDIAGK++ANP+ LL +++ ML H+   D A  I+NA   TI +G + TAD+     +S
Sbjct:  141 ESIKLISHTGCEKIIRYAFEYAVKNNRKKVTCLSKDNIMKFSDGVFHKIFNEIAKEYPQINNEHYIIDIGTARLATKPEIFDVIVTSNLYGDIISDVAAEISGSVGLAGSANIGQ-HYAMFEAVHGSAPDIAGKDIANPSGLLNAAIMMLVHIGQGDIASLIENAWKKTIEDGVH-TADIYNEQNSS 325          

BLAST of CN188826 vs. ExPASy Swiss-Prot
Match: IDH_RICTY (Isocitrate dehydrogenase [NADP] OS=Rickettsia typhi GN=icd PE=3 SV=1)

HSP 1 Score: 151.369 bits (381), Expect = 6.075e-36
Identity = 84/194 (43.30%), Postives = 122/194 (62.89%), Query Frame = -1

Query:  248 ESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEITYEEVVIDNCCMMLVKNPAAFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGEGGIALAEAVHGSAPDIAGKNLANPTALLLSSVTMLRHLELHDKADRIQNAILSTIAEGKYRTADLGGSSTTSDFTKAIC 829
            ESLK+I+     ++  YAF YA  + R++V+ + K NIM+ +DG+F +   E+A++YP+I  E  +ID     L   P  FD++V  NLYGDIISD+ A + G +GL  S NIG+   A+ EAVHGSAPDIAGK +ANP+ LL +++ ML H+   D A  I+NA   TI +G + T D+    ++S   K +C
Sbjct:  141 ESLKLISHTGCKKIIRYAFEYAVKNNRKKVTCLSKDNIMKFSDGIFHRVFNEIAKEYPQIDNEHYIIDIGTAKLATTPEIFDIIVTSNLYGDIISDVAAEISGSVGLAGSANIGQ-HYAMFEAVHGSAPDIAGKGIANPSGLLNAAIMMLVHIGQGDIASLIENAWKKTIEDGVH-TFDIYSEHSSS---KKVC 329          

BLAST of CN188826 vs. ExPASy Swiss-Prot
Match: LEU3_LACLA (3-isopropylmalate dehydrogenase OS=Lactococcus lactis subsp. lactis GN=leuB PE=3 SV=3)

HSP 1 Score: 150.599 bits (379), Expect = 1.036e-35
Identity = 77/182 (42.31%), Postives = 118/182 (64.84%), Query Frame = -1

Query:  251 RVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEITYEEVVIDNCCMMLVKNPAAFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGEGGIALAEAVHGSAPDIAGKNLANPTALLLSSVTMLRH-LELHDKADRIQNAILSTIAEGKYRTADLGGSSTTSDFTKAI 793
            R+  +AF  A++  R+ ++++ K N++  T  L+ K   E+A++YP++  E  ++D+C M+L+ NP  FDV+V  NL+GDI+SD  + L G LG+ PS + G  G+AL E +HGSAPDIAGK +ANP +++LS   MLR      D A  I+ A+  T  +G   T DLGG++TT + T+AI
Sbjct:  161 RILHFAFKSAQSRPRKLLTSVDKQNVLA-TSKLWRKMADEIADEYPDVRLEHQLVDSCAMLLITNPQQFDVIVTENLFGDILSDEASSLAGSLGVMPSSSHGFNGLALYEPIHGSAPDIAGKGIANPVSMILSIAMMLRESFGQEDGAAMIEKAVTQTFTDG-ILTKDLGGTATTKEMTEAI 340          

BLAST of CN188826 vs. ExPASy Swiss-Prot
Match: IDH_RICPR (Isocitrate dehydrogenase [NADP] OS=Rickettsia prowazekii GN=icd PE=3 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 1.353e-35
Identity = 83/194 (42.78%), Postives = 122/194 (62.89%), Query Frame = -1

Query:  248 ESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEITYEEVVIDNCCMMLVKNPAAFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGEGGIALAEAVHGSAPDIAGKNLANPTALLLSSVTMLRHLELHDKADRIQNAILSTIAEGKYRTADLGGSSTTSDFTKAIC 829
            ES+K+I+     ++  YAF YA  + R++V+ + K NIM+ +DG+F +   E+A++YP+I  E  +ID     L   P  FD++V  NLYGDIISD+ A + G +GL  S NIG+   A+ EAVHGSAPDIAGK +ANP+ LL +++ ML H+   D A  I+NA   TI +G + T D+    ++S   K +C
Sbjct:  141 ESMKLISHTGCKKIIRYAFEYAIKNNRKKVTCLTKDNIMKFSDGIFHRVFNEIAKEYPQINNEHYIIDIGTAKLATKPEIFDIIVTSNLYGDIISDVAAEISGSVGLAGSANIGQ-HYAMFEAVHGSAPDIAGKGIANPSGLLNAAIMMLVHIGQGDIASLIENAWKKTIEDGVH-TFDIYNEHSSS---KKVC 329          

BLAST of CN188826 vs. ExPASy Swiss-Prot
Match: LEU3_SULSO (3-isopropylmalate dehydrogenase OS=Sulfolobus solfataricus GN=leuB PE=3 SV=1)

HSP 1 Score: 149.058 bits (375), Expect = 3.015e-35
Identity = 84/207 (40.58%), Postives = 123/207 (59.42%), Query Frame = -1

Query:  239 GVVESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEITYEEVVIDNCCMMLVKNPAAFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGEGGIALAEAVHGSAPDIAGKNLANPTALLLSSVTMLRHLELHDKADR-------IQNAILSTIAEGKYRTADLGGSSTTSDFTKAICDHL 838
            GV  ++K+ T  AS R+   A +YA    R +V+ +HKAN+M+ TDGLF   CRE+ +   ++ +EE+ +D     LV++P  FDV+V  N+YGDI+SD  + + G LGL PS NIG+   ++ E VHG+A DIAGK +ANPTA LLS   ML  +    K ++       ++NAI+ T   G   T D+GGS+   D    I  ++
Sbjct:  134 GVTIAIKVTTEFASKRIVNVALNYALMR-RRKVTCVHKANVMRVTDGLFASVCREILKG--KVNFEEMYVDAAAANLVRDPTRFDVIVTSNVYGDILSDEASQIAGSLGLAPSANIGDRK-SMFEPVHGAAFDIAGKGIANPTAFLLSVSMMLSRMYELSKENKYILASKSLENAIIETYKSGNKLTEDVGGSAKLKDMVDEIYKYM 336          

BLAST of CN188826 vs. ExPASy Swiss-Prot
Match: IDH_RICCN (Isocitrate dehydrogenase [NADP] OS=Rickettsia conorii GN=icd PE=3 SV=1)

HSP 1 Score: 148.288 bits (373), Expect = 5.143e-35
Identity = 82/187 (43.85%), Postives = 118/187 (63.10%), Query Frame = -1

Query:  269 ESLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEITYEEVVIDNCCMMLVKNPAAFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGEGGIALAEAVHGSAPDIAGKNLANPTALLLSSVTMLRHLELHDKADRIQNAILSTIAEGKYRTADLGGSSTTS 829
            ES+K+I+     ++  YAF YA  + R++V  + K NIM+ +DG+  K   E+A++YP+I     +ID     L   P  FDV+V  NLYGDIISD+ A + G +GL  S NIG+   A+ EAVHGSAPDIAGK++ANP+ LL +++ ML H+   D A  I+NA   TI +G + TAD+    ++S
Sbjct:  141 ESMKLISHTGCEKIIRYAFEYAVKNNRKKVMCLSKDNIMKFSDGVLHKVFNEIAKEYPQINNAHYIIDIGTARLATKPEIFDVIVTSNLYGDIISDVAAEISGSVGLAGSANIGQ-HYAMFEAVHGSAPDIAGKDIANPSGLLNAAIMMLVHIGQGDIATLIENAWKKTIEDGVH-TADIYNEQSSS 325          

BLAST of CN188826 vs. ExPASy Swiss-Prot
Match: DLPA_LEGPH (Protein dlpA OS=Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) GN=dlpA PE=3 SV=1)

HSP 1 Score: 144.821 bits (364), Expect = 5.686e-34
Identity = 74/195 (37.95%), Postives = 121/195 (62.05%), Query Frame = -1

Query:  242 SLKIITRQASLRVAEYAFHYAKTHGRERVSAIHKANIMQKTDGLFLKCCREVAEKYPEITYEEVVIDNCCMMLVKNPAAFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGEGGIALAEAVHGSAPDIAGKNLANPTALLLSSVTMLRHLELHDKADRIQNAILSTIAEGKYRTADLGGSSTTSDFTKAICDH 826
            +L++ ++    R+ ++AF +A   G  RV+   K N+++++     K     A++YP+I  + + +D   + L+K+P  F V+V  N++GDI+SD+ AG++GGLGL PS NIG+ G +  E VHGS P I  KN ANP+A+ L+   +L H    D+A +I NA++  I E ++ T DLGG +TT+D   A+ +H
Sbjct:  173 ALRLQSKSGLTRLFDFAFKHAMQTGMPRVTLADKPNVLRESGEFTRKIFESTAQRYPKIQADILNVDAVALWLIKSPEKFGVIVAENMFGDILSDVGAGVMGGLGLAPSANIGDKG-SYFEPVHGSGPRIR-KNCANPSAMFLTISMLLNHFGYPDRAKKIVNAVMQVIKEKRFITYDLGGHATTTDMANAVIEH 365