CX043705

BLAST of CX043705 vs. ExPASy Swiss-Prot
Match: HMCS2_RAT (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Rattus norvegicus GN=Hmgcs2 PE=2 SV=1)

HSP 1 Score: 289.656 bits (740), Expect = 9.679e-78
Identity = 138/219 (63.01%), Postives = 166/219 (75.80%), Query Frame = 2

Query:   17 TMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALD 673
            T  K+VGILA+++YFP   V Q  LE  +    GKYT+GLGQ  M FCS  ED+ S+ LT V  L+E+ K+    +GRLEVG+ET+IDKSK++KT LM++F+  GNTDIEG+D+TNACYGGTA+LFN  NW+ESS WDGRY LVVC D AVY  G  RPTGGA AV ML+GP AP+  E  LRG+HM +AYDFYKPNLASEYP+VDGKLS  CYL ALD
Sbjct:   49 TWPKDVGILALEVYFPAQYVDQTDLEKFNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERTKLPWDAVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSYWDGRYALVVCGDIAVYPSGNPRPTGGAGAVAMLIGPKAPLVLEQGLRGTHMENAYDFYKPNLASEYPLVDGKLSIQCYLRALD 267          

BLAST of CX043705 vs. ExPASy Swiss-Prot
Match: HMCS2_PIG (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Sus scrofa GN=HMGCS2 PE=2 SV=1)

HSP 1 Score: 288.5 bits (737), Expect = 2.156e-77
Identity = 137/219 (62.56%), Postives = 167/219 (76.26%), Query Frame = 2

Query:   17 TMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALD 673
            T  K+VGILA+++YFP   V Q  LE  D    G+YT+GLGQ  M FCS  ED+ S+ LT V  L+E+ ++    +G LEVG+ET+IDKSKS+KT LM++F+  GNTDIEG+D+TNACYGGTA+LFN  NWVESS+WDGRY +VVC D AVY  G +RPTGGA AV MLVGP+AP+A E  LRG+HM +AYDFYKPN  SEYP+VDGKLS  CYL ALD
Sbjct:   49 TWPKDVGILALEVYFPAQYVDQTDLEKFDNVEAGRYTVGLGQTHMGFCSVQEDINSLCLTVVQRLMERTQLPWDSVGWLEVGTETIIDKSKSVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWVESSAWDGRYAVVVCGDIAVYPRGNSRPTGGAGAVAMLVGPEAPLALERGLRGTHMENAYDFYKPNATSEYPLVDGKLSIQCYLRALD 267          

BLAST of CX043705 vs. ExPASy Swiss-Prot
Match: HMCS2_BOVIN (Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Bos taurus GN=HMGCS2 PE=2 SV=1)

HSP 1 Score: 287.73 bits (735), Expect = 3.678e-77
Identity = 137/219 (62.56%), Postives = 167/219 (76.26%), Query Frame = 2

Query:   17 TMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALD 673
            T  K+VGILAM++YFP   V Q  LE  +    G+YT+GLGQ  M FCS  EDV S+ LT V  L+E+ ++    +GRLEVG+ET+IDKSK++KT LM++F+  GNTDIEG+D+TNACYGGTA+LFN  NW+ESSSWDGRY LVVC D AVY  G ARPTGGA AV MLVGP+AP+  E  LRG+HM + YDFYKP++ SEYP+VDGKLS  CYL ALD
Sbjct:   49 TWPKDVGILAMEVYFPAQYVDQTELEKFNKVEAGRYTVGLGQTQMGFCSVQEDVNSLCLTVVQQLMERTQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLVGPEAPLVLERGLRGTHMENVYDFYKPDVTSEYPLVDGKLSIQCYLRALD 267          

BLAST of CX043705 vs. ExPASy Swiss-Prot
Match: HMCS1_BLAGE (Hydroxymethylglutaryl-CoA synthase 1 OS=Blattella germanica GN=HMGCS-1 PE=2 SV=1)

HSP 1 Score: 280.026 bits (715), Expect = 7.669e-75
Identity = 136/215 (63.26%), Postives = 168/215 (78.14%), Query Frame = 2

Query:   29 NVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALD 673
            +VGI+A+++ FP   V Q  LE +D  S GKYT+GLGQ  M FC++ ED+ S+ LT V+ L+E++ I   QIGRLEVG+ET++DKSKS+KT LMQ+F+   NTDIEGVD+ NACYGGT+ALFN ++WVESSSWDGRY LVV  D AVYA+G ARPTGGA AV MLVG +AP+ F+  +R SHM HAYDFYKP+L+S YP VDGKLS  CYL ALD
Sbjct:    5 DVGIVALELIFPSQYVDQVDLEVYDNVSAGKYTVGLGQARMGFCTDREDINSLCLTVVSRLMERWSIPYSQIGRLEVGTETLLDKSKSVKTVLMQLFKD--NTDIEGVDTVNACYGGTSALFNAISWVESSSWDGRYALVVAGDIAVYAKGSARPTGGAGAVAMLVGANAPLVFDRGVRSSHMQHAYDFYKPDLSSLYPTVDGKLSIQCYLSALD 217          

BLAST of CX043705 vs. ExPASy Swiss-Prot
Match: HMCSB_DICDI (Hydroxymethylglutaryl-CoA synthase B OS=Dictyostelium discoideum GN=hgsB PE=3 SV=1)

HSP 1 Score: 279.641 bits (714), Expect = 1.002e-74
Identity = 130/216 (60.19%), Postives = 168/216 (77.78%), Query Frame = 2

Query:   26 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALD 673
            K++GI A+DIYFP T V Q  L+ +D  S GKYTIGLGQ  M+F  + ED++SM++T+V  ++ KY ID + IGRLEVG+ET+IDKSKS+K+ +M +F+++GNT +EGVD+ NACYGGT ALFN + W+ESS WDGRY LVV  D AVY++G ARPTGGA  V ML+GP+A + F+  LRG+HM +  DFYKP+L+SEYP VDGKLS  CYL ALD
Sbjct:    5 KDIGICAIDIYFPQTYVNQSELKKYDKVSNGKYTIGLGQTNMSFVGDREDIVSMAMTSVKMMMSKYSIDYQSIGRLEVGTETIIDKSKSVKSSIMSLFQEYGNTSLEGVDTLNACYGGTNALFNSLQWIESSYWDGRYALVVTGDIAVYSKGAARPTGGAGVVTMLIGPNATLIFDQSLRGTHMENVNDFYKPDLSSEYPYVDGKLSIECYLRALD 220          

BLAST of CX043705 vs. ExPASy Swiss-Prot
Match: HMCS_YEAST (Hydroxymethylglutaryl-CoA synthase OS=Saccharomyces cerevisiae GN=ERG13 PE=1 SV=1)

HSP 1 Score: 277.715 bits (709), Expect = 3.806e-74
Identity = 132/220 (60.00%), Postives = 167/220 (75.91%), Query Frame = 2

Query:   14 KTMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALD 673
            KT  +NVGI  + IY P  CV Q  LE  DG S+GKYTIGLGQ  M+F ++ ED+ SMSLT ++ L++ Y ID  +IGRLEVG+ET+IDKSKS+K+ LMQ+F +  NTD+EG+D+ NACYGGT ALFN +NW+ES++WDGR  +VVC D A+Y +G ARPTGGA  V M +GPDAP+ F+S +R S+M HAYDFYKP+  SEYP VDG  S TCY+ ALD
Sbjct:   43 KTRPQNVGIKGIQIYIPTQCVNQSELEKFDGVSQGKYTIGLGQTNMSFVNDREDIYSMSLTVLSKLIKSYNIDTNKIGRLEVGTETLIDKSKSVKSVLMQLFGE--NTDVEGIDTLNACYGGTNALFNSLNWIESNAWDGRDAIVVCGDIAIYDKGAARPTGGAGTVAMWIGPDAPIVFDS-VRASYMEHAYDFYKPDFTSEYPYVDGHFSLTCYVKALD 259          

BLAST of CX043705 vs. ExPASy Swiss-Prot
Match: HMCS_SCHPO (Hydroxymethylglutaryl-CoA synthase OS=Schizosaccharomyces pombe GN=hcs1 PE=1 SV=1)

HSP 1 Score: 267.7 bits (683), Expect = 3.939e-71
Identity = 128/216 (59.26%), Postives = 164/216 (75.93%), Query Frame = 2

Query:   26 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALD 673
            K++GI  + +Y P   V+Q ALEAHDG S GKYTIGLG   MAF  + ED+ S  LTA++ L+++Y+ID  +IGRLEVG+ET+IDKSKS+K+ LMQ+F    N ++EG+D  NACYGG  ALFN ++W+ESS+WDGR G+VV  D A+YA+G ARPTGGA  V +LVGP+AP+ FE  LRG++M HAYDFYKP+L SEYP VDG  S  CY+ ALD
Sbjct:    6 KDIGIKGLVLYTPNQYVEQAALEAHDGVSTGKYTIGLGLTKMAFVDDREDIYSFGLTALSQLIKRYQIDISKIGRLEVGTETIIDKSKSVKSVLMQLFGD--NHNVEGIDCVNACYGGVNALFNTIDWIESSAWDGRDGIVVAGDIALYAKGNARPTGGAGCVALLVGPNAPIVFEPGLRGTYMQHAYDFYKPDLTSEYPYVDGHFSLECYVKALD 219          

BLAST of CX043705 vs. ExPASy Swiss-Prot
Match: HMCS2_BLAGE (Hydroxymethylglutaryl-CoA synthase 2 OS=Blattella germanica GN=HMGCS-2 PE=2 SV=1)

HSP 1 Score: 265.003 bits (676), Expect = 2.553e-70
Identity = 126/216 (58.33%), Postives = 163/216 (75.46%), Query Frame = 2

Query:   26 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLSQTCYLMALD 673
            ++VGI+ +++ FP   V Q  LE +D  S GKYT+GLGQ+ M  C++ ED+ S+ LTAV  L+E+  ID   IG LEVG+ET++DK KS+KT LMQ+FE+ GNTD+EG+D+ NACY GTAALFN + W+ESSSWDGRY +VV  D A+YA+    PTGGA A++ML+G +AP+  +  +R SHM HAYDFYKP+L SEYPVVDGKLS  CYL ALD
Sbjct:    6 EDVGIIGIEMIFPSLYVDQAELETYDEVSPGKYTMGLGQDKMGVCTDREDINSLCLTAVDKLMERNNIDYNDIGWLEVGTETILDKVKSVKTVLMQLFEESGNTDVEGIDTINACYRGTAALFNALIWIESSSWDGRYAIVVAADIAIYAK-ECSPTGGAGALLMLIGANAPIVIDRGVRASHMKHAYDFYKPDLMSEYPVVDGKLSVQCYLSALD 220          

BLAST of CX043705 vs. ExPASy Swiss-Prot
Match: HMCS_CAEEL (Hydroxymethylglutaryl-CoA synthase OS=Caenorhabditis elegans GN=F25B4.6 PE=2 SV=2)

HSP 1 Score: 213.001 bits (541), Expect = 1.151e-54
Identity = 111/221 (50.23%), Postives = 146/221 (66.06%), Query Frame = 2

Query:   17 TMAKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNTDIEGVDSTNACYGGTAALFNCVNWVE-SSSWDGRYGLVVCTDSAVYAEGPARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKP--NLASEYPVVDGKLSQTCYLMAL 670
            T   +VGI A+++YFP   V Q  LE  +  S GKYTIGLGQ+ M FCS+ ED++S+SLT    L+E YKI    IG L VG+ET+IDKSKS+KT LM +F   GN+DIEGVD  NAC+GG  AL + ++WV  +   D +  +VV  D A+Y EGPAR TGGA A+  L+ PDA +  + +    HM + +DF+KP   + SEYPVVDG LS + YL A+
Sbjct:    9 TPVTDVGIGAIELYFPQNFVDQNDLEKFNNVSSGKYTIGLGQQQMGFCSDNEDIVSISLTVTRKLIETYKISTDSIGCLVVGTETMIDKSKSVKTALMDLFP--GNSDIEGVDIKNACFGGAQALLHAIDWVTVNHPLDKKNAIVVVADIAIYEEGPARCTGGAGAIAFLICPDASIPIDRQFSACHMKNTWDFFKPITPIPSEYPVVDGSLSLSSYLEAV 227          

BLAST of CX043705 vs. ExPASy Swiss-Prot
Match: Y1379_METKA (UPF0219 protein MK1379 OS=Methanopyrus kandleri GN=MK1379 PE=3 SV=1)

HSP 1 Score: 67.781 bits (164), Expect = 5.982e-11
Identity = 61/210 (29.05%), Postives = 94/210 (44.76%), Query Frame = 2

Query:   23 AKNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQECMAFCSEVEDVISMSLTAVTNLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQIFEKFGNT-DIEGVDSTNACYGGTAALFNCVNWVESSSWDGRYGLVVCTDSAVYAEG-PARPTGGAAAVVMLVGPDAPVAFESKLRGSHMSHAYDFYKPNLASEYPVVDGKLS 646
            ++ VGI+    Y P   ++ E + A  G        GL  E  +  SE ED  ++++ A  N + + +IDPK IG + VGSE+      ++K     +    G T D+   D   AC  GTAA+  C   V S     +YGL +  D+A  A G P   T  A     ++G    VA E +   S+ +   DF++      YP   G+ +
Sbjct:    4 SERVGIVGYGAYVPRYRIKAEEIAAVWGDDVDSIKSGLMIEEKSVPSETEDSATIAVEAAKNAVARAEIDPKDIGAIYVGSES---PPYAVKPTATIVAAAIGATPDLTAADYEFACKAGTAAIQTCAGLVASGMI--KYGLAIGADTAQGAPGDPLEYTAAAGGAAFVIGRKKLVA-EMEGTYSYTTDTPDFWRRE-GQPYPRHGGRFT 206