EY665513

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: NEDD4_MOUSE (E3 ubiquitin-protein ligase NEDD4 OS=Mus musculus GN=Nedd4 PE=1 SV=3)

HSP 1 Score: 183.341 bits (464), Expect = 1.477e-45
Identity = 106/236 (44.92%), Postives = 149/236 (63.14%), Query Frame = 1

Query:   34 ISVRRAYILEDSYNQLRMRSTQDL-KGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNS-VYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            + +RRA ILEDSY ++      DL K RL + F GE+G+D GG+ REW+ L+S+ +F+    LF     ++ T Q NPNS +   +HLSYFKF+GRV G A++ G+LLD  F R FYK +L   +T HD+E++D +Y+ +L+W+LEND ++ LDL F ID   E+L      Q   +EL  GG  I VT +NK +Y+ LV + R    I+  + AF EGF ELIP +LI IF + E
Sbjct:  532 MKLRRANILEDSYRRIMGVKRADLLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITLHDMESVDSEYYSSLRWILENDPTE-LDLRFIID---EELF----GQTHQHELKTGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENE 759          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: NEDD4_HUMAN (E3 ubiquitin-protein ligase NEDD4 OS=Homo sapiens GN=NEDD4 PE=1 SV=3)

HSP 1 Score: 183.341 bits (464), Expect = 1.477e-45
Identity = 104/236 (44.07%), Postives = 150/236 (63.56%), Query Frame = 1

Query:   34 ISVRRAYILEDSYNQLR-MRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNS-VYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            + +RRA +LEDSY ++  ++    LK RL + F GE+G+D GG+ REW+ L+S+ +F+    LF     ++ T Q NPNS +   +HLSYFKF+GRV G A++ G+LLD  F R FYK +L   +T HD+E++D +Y+ +L+W+LEND ++ LDL F ID   E+L      Q   +EL  GG  I VT +NK +Y+ LV + R    I+  + AF EGF ELIP +LI IF + E
Sbjct:  964 MKLRRATVLEDSYRRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLHKPITLHDMESVDSEYYNSLRWILENDPTE-LDLRFIID---EELF----GQTHQHELKNGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENE 1191          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: ITCH_MOUSE (E3 ubiquitin-protein ligase Itchy OS=Mus musculus GN=Itch PE=1 SV=2)

HSP 1 Score: 181.8 bits (460), Expect = 4.299e-45
Identity = 97/237 (40.93%), Postives = 144/237 (60.76%), Query Frame = 1

Query:   28 LRISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            ++I+V R  + EDS+ Q+   S QDL+ RL V F GEEG+D GG+ REW+ LLS  + +    LF   G ++   Q NP S    +HL YF+F+GR +  ALF G+ +D  F+  FYK IL   V   D+E+IDP+++ +L W+ EN+I +  L++ FS+D    K IL    ++  ++L P G NI VTEENK +Y+ +VAE RL+  +     AF EGF E++P + +  F  +E
Sbjct:  509 IKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVD----KEIL---GEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKE 738          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: ITCH_HUMAN (E3 ubiquitin-protein ligase Itchy homolog OS=Homo sapiens GN=ITCH PE=1 SV=2)

HSP 1 Score: 181.8 bits (460), Expect = 4.299e-45
Identity = 97/237 (40.93%), Postives = 144/237 (60.76%), Query Frame = 1

Query:   28 LRISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            ++I+V R  + EDS+ Q+   S QDL+ RL V F GEEG+D GG+ REW+ LLS  + +    LF   G ++   Q NP S    +HL YF+F+GR +  ALF G+ +D  F+  FYK IL   V   D+E+IDP+++ +L W+ EN+I +  L++ FS+D    K IL    ++  ++L P G NI VTEENK +Y+ +VAE RL+  +     AF EGF E++P + +  F  +E
Sbjct:  548 IKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVD----KEIL---GEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKE 777          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: SMUF1_MOUSE (E3 ubiquitin-protein ligase SMURF1 OS=Mus musculus GN=Smurf1 PE=1 SV=2)

HSP 1 Score: 181.03 bits (458), Expect = 7.332e-45
Identity = 102/235 (43.40%), Postives = 136/235 (57.87%), Query Frame = 1

Query:   31 RISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFT-TVGNESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            RI V R  I E+SY Q+     +DLK RL V F+GEEG+D GG+ REW  LL   + +    LF  +  N  T Q NP+S    +HLSYF FVGR++G A+F G  ++  FT  FYK +LG  +   D+E++DP+  K+L W+LENDI+ VLD TF ++ +    IL        +EL P GRN+ VTEENK +YV L    R    I     A  +GF ELIP  L+  F  +E
Sbjct:  374 RIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRIL-------QHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKE 601          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: SMUF2_MOUSE (E3 ubiquitin-protein ligase SMURF2 OS=Mus musculus GN=Smurf2 PE=2 SV=1)

HSP 1 Score: 180.644 bits (457), Expect = 9.576e-45
Identity = 99/235 (42.13%), Postives = 136/235 (57.87%), Query Frame = 1

Query:   31 RISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            RI V R  I E+SY Q+     +DL  RL + F+GEEG+D GG+ REW  LLS  + +    LF    ++  T Q NP+S    EHLSYF FVGR++G A+F G  +D  FT  FYK +LG  +T  D+E +DPD   +L W+LENDI+ VLD TF ++ +          ++  +EL P G++I VTEENK +YV L    R    I     A  +GF E+IP  L+  F ++E
Sbjct:  394 RIEVSREEIFEESYRQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGVLDHTFCVEHN-------AYGEIIQHELKPNGKSIPVTEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKE 621          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: NEDD4_DROME (E3 ubiquitin-protein ligase Nedd-4 OS=Drosophila melanogaster GN=Nedd4 PE=1 SV=2)

HSP 1 Score: 180.259 bits (456), Expect = 1.251e-44
Identity = 98/236 (41.53%), Postives = 143/236 (60.59%), Query Frame = 1

Query:   34 ISVRRAYILEDSYNQLRMRSTQDL-KGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDK--GALLFTTVGNESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            I +RR  ILEDSY  +   +  DL K +L V F+GE G+D GGL REW+ LLS+ +F+   G   ++ + N +    N + +   EHLSYFKF+GR+ G A++ G+LLD  F R FYK +L   +   D+E++D +Y+ +L W+ END   +L+LTF +D D          Q + +EL PGG NI VT ENK +Y+ LV E R    ++  +++FL+GF  +IP  LI IF + E
Sbjct:  652 IRIRRTSILEDSYRIISSVTKTDLLKTKLWVEFEGETGLDYGGLAREWFYLLSKEMFNPYYGLFEYSAMDNYTLQINNGSGLCNEEHLSYFKFIGRIAGMAVYHGKLLDAFFIRPFYKMMLQKPIDLKDMESVDTEYYNSLMWIKEND-PRILELTFCLDED-------VFGQKSQHELKPGGANIDVTNENKDEYIKLVIEWRFVARVKEQMSSFLDGFGSIIPLNLIKIFDEHE 879          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: SMUF1_XENLA (E3 ubiquitin-protein ligase SMURF1 OS=Xenopus laevis GN=smurf1 PE=2 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 1.633e-44
Identity = 99/235 (42.13%), Postives = 137/235 (58.30%), Query Frame = 1

Query:   31 RISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFT-TVGNESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            R+ V R  I E+SY Q+     +DLK RL V F+GEEG+D GG+ REW  LL   + +    LF  +  N  T Q NP+S    +HLSYF FVGR++G A+F G  ++  FT  FYK +LG  +   D+E++DP+  K+L W+LENDI+ VLD TF ++ +    +L        +EL P G+N++VTEENK +YV L    R    I     A  +GF ELIP  L+  F  +E
Sbjct:  374 RVEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITSVLDHTFCVEHNAFGRLL-------QHELKPNGKNLQVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFEQKE 601          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: SMUF1_DROME (E3 ubiquitin-protein ligase Smurf1 OS=Drosophila melanogaster GN=lack PE=1 SV=3)

HSP 1 Score: 179.104 bits (453), Expect = 2.786e-44
Identity = 98/235 (41.70%), Postives = 138/235 (58.72%), Query Frame = 1

Query:   31 RISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            R+ V R  I E+SY  +     +D++ RL V F+GEEG+D GG+ REW  LLSR + +    LF    ++  T Q NP+S    +HLSYF FVGR +G A+F G  LD  FT  FYK +L   +T  DIE +DPD  ++L WMLE++IS +++ TFS++ +    ++        +EL PGG +I VTEENK +YV L   +R    I     A  +GF ELIP  L+  F ++E
Sbjct:  703 RLEVSRNEIFEESYRLIMKMRAKDMRKRLMVKFKGEEGLDYGGVAREWLHLLSREMLNPQYGLFQYSRDDHYTLQINPDSGVNPDHLSYFHFVGRTLGIAVFHGHCLDGGFTTPFYKQLLNKPITLGDIEGVDPDLHRSLTWMLESNISGIIESTFSVENNSFGALVV-------HELKPGGASIPVTEENKREYVKLYVNYRFMRGIEQQFLALQKGFCELIPSHLLRPFDERE 930          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: SMUF2_HUMAN (E3 ubiquitin-protein ligase SMURF2 OS=Homo sapiens GN=SMURF2 PE=1 SV=1)

HSP 1 Score: 178.718 bits (452), Expect = 3.639e-44
Identity = 98/235 (41.70%), Postives = 135/235 (57.45%), Query Frame = 1

Query:   31 RISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            RI V R  I E+SY Q+     +DL  RL + F+GEEG+D GG+ REW  LLS  + +    LF    ++  T Q NP+S    EHLSYF FVGR++G A+F G  +D  FT  FYK +LG  +T  D+E +DPD   +L W+LENDI+ VLD TF ++ +          ++  +EL P G++I V EENK +YV L    R    I     A  +GF E+IP  L+  F ++E
Sbjct:  394 RIEVSREEIFEESYRQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGVLDHTFCVEHN-------AYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKE 621