EY665513

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: SMUF1_HUMAN (E3 ubiquitin-protein ligase SMURF1 OS=Homo sapiens GN=SMURF1 PE=1 SV=2)

HSP 1 Score: 178.718 bits (452), Expect = 3.639e-44
Identity = 101/235 (42.98%), Postives = 135/235 (57.45%), Query Frame = 1

Query:   31 RISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFT-TVGNESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            RI V R  I E+SY Q+     +DLK RL V F+GEEG+D GG+ REW  LL   + +    LF  +  N    Q NP+S    +HLSYF FVGR++G A+F G  ++  FT  FYK +LG  +   D+E++DP+  K+L W+LENDI+ VLD TF ++ +    IL        +EL P GRN+ VTEENK +YV L    R    I     A  +GF ELIP  L+  F  +E
Sbjct:  400 RIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRIL-------QHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKE 627          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: WWP1_MOUSE (NEDD4-like E3 ubiquitin-protein ligase WWP1 OS=Mus musculus GN=Wwp1 PE=1 SV=2)

HSP 1 Score: 177.948 bits (450), Expect = 6.207e-44
Identity = 96/239 (40.17%), Postives = 146/239 (61.09%), Query Frame = 1

Query:   22 SPLRISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVG-NESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            S ++I+V R  + EDS+ Q+      DL+ RL V F+GEEG+D GGL REW+ LLS  + +    LF   G N    Q NP S    +HLSYF F+GR +  ALF G+ +D  F+  FYK +L  K+T  D+E+ID +++ +L W+ +N+I +  L++ FS+D +    IL    +VT ++L  GG NI VTEENK +Y+ L+ E R +  ++    AFL+GF E++P + +  F ++E
Sbjct:  561 SHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDME----IL---GKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKE 792          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: WWP1_HUMAN (NEDD4-like E3 ubiquitin-protein ligase WWP1 OS=Homo sapiens GN=WWP1 PE=1 SV=1)

HSP 1 Score: 177.948 bits (450), Expect = 6.207e-44
Identity = 96/239 (40.17%), Postives = 146/239 (61.09%), Query Frame = 1

Query:   22 SPLRISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVG-NESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            S ++I+V R  + EDS+ Q+      DL+ RL V F+GEEG+D GGL REW+ LLS  + +    LF   G N    Q NP S    +HLSYF F+GR +  ALF G+ +D  F+  FYK +L  K+T  D+E+ID +++ +L W+ +N+I +  L++ FS+D +    IL    +VT ++L  GG NI VTEENK +Y+ L+ E R +  ++    AFL+GF E++P + +  F ++E
Sbjct:  565 SHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDME----IL---GKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKE 796          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: SMUF2_XENLA (E3 ubiquitin-protein ligase SMURF2 OS=Xenopus laevis GN=smurf2 PE=2 SV=1)

HSP 1 Score: 176.407 bits (446), Expect = 1.806e-43
Identity = 97/235 (41.28%), Postives = 136/235 (57.87%), Query Frame = 1

Query:   31 RISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            RI V R  I E+SY Q+     +DL  RL + F+GEEG+D GG+ REW  LLS  + +    LF    ++  T Q NP+S    EHLSYF FVGR++G A+F G  +D  FT  FYK +LG  +T  D+E++DPD   +L W+LENDI+ VLD TF ++ +          ++  +EL P G++I VTE+ K +YV L    R    I     A  +GF E+IP  L+  F ++E
Sbjct:  397 RIEVSREEIFEESYRQVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHDMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKPITLDDMESVDPDLHNSLVWILENDITGVLDHTFCVEHN-------AYGELIQHELKPSGKSIPVTEDTKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKAFDEKE 624          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: SUDX_DROME (E3 ubiquitin-protein ligase Su(dx) OS=Drosophila melanogaster GN=Su(dx) PE=1 SV=1)

HSP 1 Score: 175.637 bits (444), Expect = 3.081e-43
Identity = 93/239 (38.91%), Postives = 141/239 (59.00%), Query Frame = 1

Query:   22 SPLRISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVG-NESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            S ++I+V R  + EDSY+Q+      +L+ RL + F+GEEG+D GG++REW+ LLS  + +    LF     N  + Q NP S    +HL YFKF+GR +  AL+ G+ +   FT  FYK +L  K+T  DIE IDP+++ +L W+ +N+I +  L+L FS+D +          Q+  +EL   G   +VTEENK +Y+ L+ E R+T  I      FLEGF E++P E +  F ++E
Sbjct:  592 SHIKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFYNSLIWVKDNNIDECGLELWFSVDFE-------VLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERE 823          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: SMUF2_DANRE (E3 ubiquitin-protein ligase SMURF2 OS=Danio rerio GN=smurf2 PE=2 SV=1)

HSP 1 Score: 175.637 bits (444), Expect = 3.081e-43
Identity = 96/235 (40.85%), Postives = 136/235 (57.87%), Query Frame = 1

Query:   31 RISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            RI V R  I E+SY Q+     +DL  RL V F+GEEG+D GG+ REW  LLS  + +    LF    ++  T Q NP+S    EHLSYF FVGR++G A+F G  +D  FT  FYK +LG  +T  D+E++DPD   +L W+L+NDI+ VLD TF ++ +          ++  +EL P G++I VT++ K +YV L    R    I     A  +GF E+IP  L+  F ++E
Sbjct:  411 RIEVSREEIFEESYRQVMKMRPKDLWKRLMVKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKPITLDDMESVDPDLHNSLVWILDNDITGVLDHTFCVEHN-------AYGEIIQHELKPNGKSIPVTQDTKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKAFDEKE 638          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: WWP2_MOUSE (NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Mus musculus GN=Wwp2 PE=2 SV=1)

HSP 1 Score: 175.252 bits (443), Expect = 4.023e-43
Identity = 94/239 (39.33%), Postives = 143/239 (59.83%), Query Frame = 1

Query:   22 SPLRISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVG-NESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            S ++ISV R  + EDS+ Q+      DL+ RL +  +GEEG+D GG+ REW+ LLS  + +    LF   G N    Q NP S    +HL+YF+F+GR +  AL+ G+ +D  FT  FYK +L  + T  D+E+IDP+++ ++ W+ EN++ +  L+L F  D +    IL    +VT +EL  GG NI+VTEENK +Y+ L+ + R T  +     AFL+GF E+ P E +  F ++E
Sbjct:  513 SHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELFFIQDME----IL---GKVTTHELKEGGENIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKE 744          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: WWP2_HUMAN (NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Homo sapiens GN=WWP2 PE=1 SV=2)

HSP 1 Score: 173.326 bits (438), Expect = 1.529e-42
Identity = 93/239 (38.91%), Postives = 143/239 (59.83%), Query Frame = 1

Query:   22 SPLRISVRRAYILEDSYNQLRMRSTQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVG-NESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            S ++ISV R  + EDS+ Q+      DL+ RL +  +GEEG+D GG+ REW+ LLS  + +    LF   G N    Q NP S    +HL+YF+F+GR +  AL+ G+ +D  FT  FYK +L  + T  D+E+IDP+++ ++ W+ EN++ +  L+L F  D +    IL    +VT +EL  GG +I+VTEENK +Y+ L+ + R T  +     AFL+GF E+ P E +  F ++E
Sbjct:  513 SHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDME----IL---GKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKE 744          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: HECW2_MOUSE (E3 ubiquitin-protein ligase HECW2 OS=Mus musculus GN=Hecw2 PE=2 SV=1)

HSP 1 Score: 168.703 bits (426), Expect = 3.766e-41
Identity = 91/237 (38.40%), Postives = 148/237 (62.45%), Query Frame = 1

Query:   28 LRISVRRAYILEDSYNQLRMRSTQDL-KGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            L++ +RR ++LED++NQ+   S +DL + +L V F GEEG+D  G +RE++ L+SR +F+    LF    N++ T Q +P S +   H  +F+F GR++G AL    LLD  FTR FYK +L +     D+E +D ++ ++L+WM +NDI D+LDLTF++  +EE        Q+T+ EL PGG NI VTE+NK +Y++ + + R+   +     + + GF E++   L+S+F  +E
Sbjct: 1222 LKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTV--NEEVF-----GQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARE 1451          

BLAST of EY665513 vs. ExPASy Swiss-Prot
Match: HECW2_HUMAN (E3 ubiquitin-protein ligase HECW2 OS=Homo sapiens GN=HECW2 PE=1 SV=2)

HSP 1 Score: 168.703 bits (426), Expect = 3.766e-41
Identity = 91/237 (38.40%), Postives = 148/237 (62.45%), Query Frame = 1

Query:   28 LRISVRRAYILEDSYNQLRMRSTQDL-KGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPPINAFLEGFTELIPGELISIFHDQE 732
            L++ +RR ++LED++NQ+   S +DL + +L V F GEEG+D  G +RE++ L+SR +F+    LF    N++ T Q +P S +   H  +F+F GR++G AL    LLD  FTR FYK +L +     D+E +D ++ ++L+WM +NDI D+LDLTF++  +EE        Q+T+ EL PGG NI VTE+NK +Y++ + + R+   +     + + GF E++   L+S+F  +E
Sbjct: 1216 LKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTV--NEEVF-----GQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARE 1445