CV885074

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP132_MYCTU (Putative cytochrome P450 132 OS=Mycobacterium tuberculosis GN=cyp132 PE=3 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 3.357e-19
Identity = 49/131 (37.40%), Postives = 72/131 (54.96%), Query Frame = -1

Query:  197 KRSHEDLSSIPISCRETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLELEFGIILNFKHGV 589
            + S    SS+ I  RE   +  I G+R+ +GT V + +  +  D + +P+PD+F P RF   C   + R  CAYLPFG G R CIGQ FA+ E+ L    + +++ F  +P     +ELE  + L  KHGV
Sbjct:  329 QESQRYFSSVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPRWWPDPDRFDPGRF-LRCPTDRPR--CAYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGYH--VELEATLTLRPKHGV 454          

HSP 2 Score: 37.3502 bits (85), Expect = 3.357e-19
Identity = 31/116 (26.72%), Postives = 58/116 (50.00%), Query Frame = -2

Query:  568 LDEIVFKRMKESKQGSKDLLSLIVKARELETESKNVFTPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDG-FGPRELVPTALDLQQKFPYLDQVIKEAMRIY 912
            ++ ++ +R+ E    S DLL++++ A         ++    +       +LAG  TT+ A+S   YL+A +P+  + +L E+D   G R   PTA DL  K  +    ++E+ R +
Sbjct:  230 INSVIDRRLAEPTN-SADLLNVLLSA------DGGIWPRQRVRDEALTFMLAGHETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRR--PTADDL-GKLAWTTACLQESQRYF 335          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP132_MYCBO (Putative cytochrome P450 132 OS=Mycobacterium bovis GN=cyp132 PE=3 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 3.357e-19
Identity = 49/131 (37.40%), Postives = 72/131 (54.96%), Query Frame = -1

Query:  197 KRSHEDLSSIPISCRETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLELEFGIILNFKHGV 589
            + S    SS+ I  RE   +  I G+R+ +GT V + +  +  D + +P+PD+F P RF   C   + R  CAYLPFG G R CIGQ FA+ E+ L    + +++ F  +P     +ELE  + L  KHGV
Sbjct:  329 QESQRYFSSVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPRWWPDPDRFDPGRF-LRCPTDRPR--CAYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGYH--VELEATLTLRPKHGV 454          

HSP 2 Score: 37.3502 bits (85), Expect = 3.357e-19
Identity = 31/116 (26.72%), Postives = 58/116 (50.00%), Query Frame = -2

Query:  568 LDEIVFKRMKESKQGSKDLLSLIVKARELETESKNVFTPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDG-FGPRELVPTALDLQQKFPYLDQVIKEAMRIY 912
            ++ ++ +R+ E    S DLL++++ A         ++    +       +LAG  TT+ A+S   YL+A +P+  + +L E+D   G R   PTA DL  K  +    ++E+ R +
Sbjct:  230 INSVIDRRLAEPTN-SADLLNVLLSA------DGGIWPRQRVRDEALTFMLAGHETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRR--PTADDL-GKLAWTTACLQESQRYF 335          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP2E1_HUMAN (Cytochrome P450 2E1 OS=Homo sapiens GN=CYP2E1 PE=1 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 4.359e-19
Identity = 37/113 (32.74%), Postives = 58/113 (51.33%), Query Frame = -1

Query:  218 ETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDME----NPLELEFGII 544
            E  ++    GY +PKGT V   L  V  D++ FP+P+KFKPE F    E  K ++   + PF  G R C G+  A  E+ L L  + +++  +   D +    +P+ + FG I
Sbjct:  371 EATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHF--LNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDLSPIHIGFGCI 481          

HSP 2 Score: 53.5286 bits (127), Expect = 4.359e-19
Identity = 38/123 (30.89%), Postives = 60/123 (48.78%), Query Frame = -2

Query:  556 EIVFKRMKESKQG-----SKDLLSLIVKARELETES-KNVFTPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIYLVSP 906
            E V +R+KE  Q       +DL   ++   E E  S + ++T D I+    +   AG+ TTS  L   + ++  +PE+E KL  EID       +P   D +Q+ PY+D V+ E  R   + P
Sbjct:  244 EYVSERVKEHHQSLDPNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKD-RQEMPYMDAVVHEIQRFITLVP 365          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP6D4_DROME (Probable cytochrome P450 6d4 OS=Drosophila melanogaster GN=Cyp6d4 PE=2 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 9.577e-19
Identity = 45/128 (35.16%), Postives = 76/128 (59.38%), Query Frame = -1

Query:  194 IPISCRETAKEVEIG--GYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLELEF---GIILNFKHGVK 562
            +PI  RE  ++  +    + +PKGT V ++L  +  D++ FP+P+ + PERF    EE++  +P A++PFG GPR CI Q+      KL++I + +N+    + ++ +  E+EF   GI L  KHGV+
Sbjct:  384 LPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYFPDPETYDPERFS---EESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNF----NVEVMSRSEIEFENSGIALIPKHGVR 504          

HSP 2 Score: 38.891 bits (89), Expect = 9.577e-19
Identity = 32/121 (26.45%), Postives = 54/121 (44.63%), Query Frame = -2

Query:  550 KDLLSLIVKAREL----ETESKNVF---TPD---------YISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIYLVSPLV 864
            KDLL L+++ R      E + K+     TPD          I+A  +   +AG  TT    +  +Y +A +PE+  +L  E+D    +       D   K  +LD  ++E +R Y   P++
Sbjct:  267 KDLLQLLIQLRNTGKIDENDEKSFSIQKTPDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITYDSLNKMEFLDLCVQETIRKYPGLPIL 387          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP2E1_MACMU (Cytochrome P450 2E1 OS=Macaca mulatta GN=CYP2E1 PE=2 SV=1)

HSP 1 Score: 61.2326 bits (147), Expect = 9.585e-19
Identity = 36/113 (31.86%), Postives = 58/113 (51.33%), Query Frame = -1

Query:  218 ETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDME----NPLELEFGII 544
            E  ++    GY +PKGT +   L  V  D++ FP+P+KFKPE F    E  K ++   + PF  G R C G+  A  E+ L L  + +++  +   D +    +P+ + FG I
Sbjct:  371 EATRDTIFRGYIIPKGTVIVPTLDSVLYDNQEFPDPEKFKPEHFLD--ESGKFKYSDYFKPFSAGKRVCAGEGLARMELFLLLSAILQHFNLKPLVDPKDIDISPVNIGFGCI 481          

HSP 2 Score: 53.5286 bits (127), Expect = 9.585e-19
Identity = 38/125 (30.40%), Postives = 61/125 (48.80%), Query Frame = -2

Query:  556 LDEIVFKRMKESKQG-----SKDLLSLIVKARELETES-KNVFTPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIYLVSP 912
            + E V +R+KE  Q       +DL   ++   E E  S + ++T D I+    +   AG+ TTS  L   + ++  +PE+E KL  EID       +P   D +Q+ PY+D V+ E  R   + P
Sbjct:  242 IKEYVSERVKEHLQSLDPNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKD-RQEMPYMDAVVHEIQRFITLVP 365          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP27A_MOUSE (Sterol 26-hydroxylase, mitochondrial OS=Mus musculus GN=Cyp27a1 PE=1 SV=1)

HSP 1 Score: 68.5514 bits (166), Expect = 1.244e-18
Identity = 37/99 (37.37%), Postives = 53/99 (53.54%), Query Frame = -1

Query:  251 TAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERF--DPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDM 541
            T KE EI G+  PK T   L   VV++D   FPEP+ F+P R+      +     HP   +PFG G R+C+G++ A  E++L L  L + Y    +P M
Sbjct:  410 TEKETEINGFLFPKNTQFVLCHYVVSRDPSVFPEPNSFQPHRWLRKKEADNPGILHPFGSVPFGYGVRSCLGRRIAELEMQLMLSRLVQKYEIALAPGM 508          

HSP 2 Score: 45.8246 bits (107), Expect = 1.244e-18
Identity = 31/82 (37.80%), Postives = 43/82 (52.44%), Query Frame = -2

Query:  538 EHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIYLVSP----LVVEKQ 771
            E LLAG  TTS  L+  +Y ++  PE++  L  E+ G  P   VP   D     P L  VIKE +R+Y V P    ++ EK+
Sbjct:  333 ELLLAGVDTTSNTLTWALYHLSKSPEIQEALHKEVTGVVPFGKVPQHKDFAH-MPLLKAVIKETLRLYPVVPTNSRIITEKE 413          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP27B_HUMAN (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial OS=Homo sapiens GN=CYP27B1 PE=1 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 2.106e-18
Identity = 34/102 (33.33%), Postives = 57/102 (55.88%), Query Frame = -1

Query:  257 IPISCRETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSP 562
            +P + R   K++ +G Y +PK T V L     ++D   FPEP+ F+P R+     E    HP A LPFG G R+C+G++ A  E++++L  +  ++  +  P
Sbjct:  384 VPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPARW---LGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEP 482          

HSP 2 Score: 43.1282 bits (100), Expect = 2.106e-18
Identity = 27/73 (36.99%), Postives = 38/73 (52.05%), Query Frame = -2

Query:  556 EHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEID-GFGPRELVPTALDLQQKFPYLDQVIKEAMRIYLVSP 771
            E LLAG  T S  LS  +Y ++ HPEV+  L +EI     P      +  +  + P L  V+KE +R+Y V P
Sbjct:  313 ELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLKAVVKEVLRLYPVVP 385          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: C27C1_HUMAN (Cytochrome P450 27C1 OS=Homo sapiens GN=CYP27C1 PE=2 SV=1)

HSP 1 Score: 59.3066 bits (142), Expect = 2.121e-18
Identity = 34/101 (33.66%), Postives = 57/101 (56.44%), Query Frame = -1

Query:  260 IPISCRETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHS 562
            +P + R T +++ IGGY +PKGT + L     +   +NFP   +F+PER+     +  +      +PFG G R+CIG++ A  EI L +I L +++  + S
Sbjct:  245 LPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPRAKEFRPERW-LRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTS 344          

HSP 2 Score: 54.299 bits (129), Expect = 2.121e-18
Identity = 36/79 (45.57%), Postives = 47/79 (59.49%), Query Frame = -2

Query:  556 ISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEI-DGFGPRELVPTALDLQQKFPYLDQVIKEAMRIYLVSP 789
            I A   E LLAG  TTSF LS  VY++A HPEV+  +  EI    G R  VPTA D+  K P +  ++KE +R++ V P
Sbjct:  170 IYANVTEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLGERH-VPTAADV-PKVPLVRALLKETLRLFPVLP 246          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP2J3_RAT (Cytochrome P450 2J3 OS=Rattus norvegicus GN=Cyp2j3 PE=2 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 2.739e-18
Identity = 36/107 (33.64%), Postives = 59/107 (55.14%), Query Frame = -1

Query:  227 RETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVFRHSPDMENPLELEF 547
            RE A +  + G+ LPKGT +   L  + +D K +  PD F PE F  N +  K+    ++LPF +G RAC+G++ A  E+ + +  L + + F+  P +   L L+F
Sbjct:  382 REVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWATPDTFNPEHFLENGQFKKRE---SFLPFSMGKRACLGEQLARSELFIFITSLIQKFTFK--PPVNEKLSLQF 483          

HSP 2 Score: 43.1282 bits (100), Expect = 2.739e-18
Identity = 28/89 (31.46%), Postives = 43/89 (48.31%), Query Frame = -2

Query:  538 FTPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIYLVSPLVVEKQ 804
            F  + +   T +   AG+ TTS  L   +  +A +PEV+ K+ AEID    +   P   D +   PY + VI E  RI  + P  V ++
Sbjct:  296 FNEENLICSTLDLFFAGTETTSTTLRWALLCMALYPEVQEKMQAEIDRVIGQGRQPNLAD-RDSMPYTNAVIHEVQRIGNIIPFNVPRE 383          

BLAST of CV885074 vs. ExPASy Swiss-Prot
Match: CP2J6_MOUSE (Cytochrome P450 2J6 OS=Mus musculus GN=Cyp2j6 PE=2 SV=1)

HSP 1 Score: 67.781 bits (164), Expect = 2.739e-18
Identity = 40/117 (34.19%), Postives = 61/117 (52.14%), Query Frame = -1

Query:  233 IPISC-RETAKEVEIGGYRLPKGTWVWLALGVVAKDSKNFPEPDKFKPERFDPNCEEAKQRHPCAYLPFGIGPRACIGQKFAMQEIKLSLIHLYRNYVF------RHSPDMENPLEL 562
            IP++  RE A +  + G+ LPKGT V   L  + +D K +  PD F PE F  N +  K+    ++LPF +G RAC+G++ A  E+ +    L + + F      + SP   N L L
Sbjct:  375 IPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFLENGQFKKRE---SFLPFSMGKRACLGEQLARSELFIFFTSLMQKFTFNPPINEKLSPKFRNGLTL 488          

HSP 2 Score: 45.4394 bits (106), Expect = 2.739e-18
Identity = 30/109 (27.52%), Postives = 51/109 (46.79%), Query Frame = -2

Query:  538 KDLLSLIVKARELETESKNVFTPDYISAVTYEHLLAGSATTSFALSSIVYLVAAHPEVENKLLAEIDGFGPRELVPTALDLQQKFPYLDQVIKEAMRIYLVSPLVVEKQ 864
            +D +   +K      E    F  + +   T +   AG+ TTS  L   +  +A +PEV+ K+ AEID    ++      D ++  PY + VI E  R+  + PL V ++
Sbjct:  275 RDFIDAFLKEMTKYPEKTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLAD-RESMPYTNAVIHEVRRMGNIIPLNVPRE 382