CX672514

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: MP2K1_HUMAN (Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens GN=MAP2K1 PE=1 SV=2)

HSP 1 Score: 157.147 bits (396), Expect = 1.121e-37
Identity = 86/209 (41.15%), Postives = 124/209 (59.33%), Query Frame = 3

Query:  159 DLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYL-HGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQP 782
            D EK+  LG GNGG V+KV H+ +  + A K++H +  P +R Q+ RE+++L   +SP+IV  +G F    G+I+I ME+MD G+LD +L K G   E  L  ++  ++KGL+YL   HKI+HRD+KPSN+LVN+   ++K+ DFGVS  +  S+   NS+VGT +YMSPER               DIWS          G +P   P
Sbjct:   67 DFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYS-DGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSM--ANSFVGTRSYMSPERLQ-----GTHYSVQSDIWSMGLSLVEMAVGRYPIPPP 266          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: M2K1_ARATH (Mitogen-activated protein kinase kinase 1 OS=Arabidopsis thaliana GN=MKK1 PE=1 SV=2)

HSP 1 Score: 156.762 bits (395), Expect = 1.463e-37
Identity = 88/238 (36.97%), Postives = 136/238 (57.14%), Query Frame = 3

Query:  147 IAYSDLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHK-IIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQPGQRPDWAT---LMCAICFGDPPSLP 848
            ++ +DLE ++V+G G+ G V  V+H+ T + +ALKV+  + + +  R + +E+ I   +  P++V C+  F   +G ++I++E+MD G+L  LL K G   E  L+ +  ++L+GL Y+H  + IIHRD+KPSNLL+N+   +VKI DFGVSKI+  +    NS+VGT  YMSPER               DIWS          G FP+  P  +  W++   L+ AI    PP  P
Sbjct:   63 LSLADLEVIKVIGKGSSGNVQLVKHKLTQQFFALKVIQLNTEESTCRAISQELRINLSSQCPYLVSCYQSFYH-NGLVSIILEFMDGGSLADLLKKVGKVPENMLSAICKRVLRGLCYIHHERRIIHRDLKPSNLLINHRG-EVKITDFGVSKILTSTSSLANSFVGTYPYMSPERIS-----GSLYSNKSDIWSLGLVLLECATGKFPYTPPEHKKGWSSVYELVDAIVENPPPCAP 293          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: M2K2_ARATH (Mitogen-activated protein kinase kinase 2 OS=Arabidopsis thaliana GN=MKK2 PE=1 SV=2)

HSP 1 Score: 154.836 bits (390), Expect = 5.561e-37
Identity = 90/240 (37.50%), Postives = 135/240 (56.25%), Query Frame = 3

Query:  147 IAYSDLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHK-IIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQPGQRPDWAT---LMCAICFGDPPSLPDG 854
            ++ SDL+ ++V+G G+ G V  VQH+ T + +ALKV+  + D  +R+ + +E++I + +  P +V  +  F   +G I++++EYMD G+L   L       +  L+ +  Q+L+GL YLH  + IIHRD+KPSNLL+N+   +VKI DFGVS +M  +    N++VGT  YMSPER               DIWS          G FP+  P Q   W +   LM AI    PP+LP G
Sbjct:   65 LSLSDLDMVKVIGKGSSGVVQLVQHKWTGQFFALKVIQLNIDEAIRKAIAQELKINQSSQCPNLVTSYQSFYD-NGAISLILEYMDGGSLADFLKSVKAIPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLINHRG-EVKITDFGVSTVMTNTAGLANTFVGTYNYMSPERI-----VGNKYGNKSDIWSLGLVVLECATGKFPYAPPNQEETWTSVFELMEAIVDQPPPALPSG 297          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: M2K1_ORYSJ (Mitogen-activated protein kinase kinase 1 OS=Oryza sativa subsp. japonica GN=MEK1 PE=1 SV=1)

HSP 1 Score: 152.525 bits (384), Expect = 2.760e-36
Identity = 92/238 (38.66%), Postives = 135/238 (56.72%), Query Frame = 3

Query:  147 IAYSDLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHK-IIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQPGQRPDWAT---LMCAICFGDPPSLP 848
            ++  DLE +QV+G G+GG V  V+H+    +YALK +  +    VR+Q+ +E++I + T +  IV C   F   +G I +++EYMD G+L  ++ +  T  EP LA +  Q+L+GL YLH  + +IHRDIKPSNLLVN    +VKI DFGVS ++  S+   +++VGT  YM+PER               DIWS          G FP++ P +   W +   L+ AI    PPS P
Sbjct:   66 LSMDDLEMIQVIGKGSGGIVQLVRHKWVGTLYALKGIQMNIQEAVRKQIVQELKINQATQNAHIVLCHQSFYH-NGVIYLVLEYMDRGSLADIIKQVKTILEPYLAVLCKQVLEGLLYLHHERHVIHRDIKPSNLLVNRKG-EVKITDFGVSAVLASSMGQRDTFVGTYNYMAPERIS-----GSSYDYKSDIWSLGLVILECAIGRFPYI-PSEGEGWLSFYELLEAIVDQPPPSAP 295          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: MP2K2_CANFA (Dual specificity mitogen-activated protein kinase kinase 2 OS=Canis familiaris GN=MAP2K2 PE=2 SV=1)

HSP 1 Score: 150.984 bits (380), Expect = 8.030e-36
Identity = 85/209 (40.67%), Postives = 123/209 (58.85%), Query Frame = 3

Query:  159 DLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYL-HGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQP 782
            D E++  LG GNGG V KVQHR +  I A K++H +  P +R Q+ RE+++L   +SP+IV  +G F    G+I+I ME+MD G+LD +L +     E  L  ++  +L+GL+YL   H+I+HRD+KPSN+LVN+   ++K+ DFGVS  +  S+   NS+VGT +YMSPER               DIWS          G +P   P
Sbjct:   71 DFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSM--ANSFVGTRSYMSPERLQ-----GTHYSVQSDIWSMGLSLVELSIGRYPIPPP 270          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: M2K6_ARATH (Mitogen-activated protein kinase kinase 6 OS=Arabidopsis thaliana GN=MKK6 PE=1 SV=1)

HSP 1 Score: 150.984 bits (380), Expect = 8.030e-36
Identity = 89/239 (37.24%), Postives = 136/239 (56.90%), Query Frame = 3

Query:  147 IAYSDLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDS-PFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHK-IIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQPGQR---PDWATLMCAICFGDPPSLP 848
            I   DLE ++V+G G+GG V  V+H+   K +A+KV+  +    +R+Q+ +E++I + +   P +V C+  F   +G  ++++EYMD G+L  ++ +  T  EP LA +  Q+L GL YLH  + +IHRDIKPSNLLVN+   +VKI+DFGVS  +  S+   +++VGT  YMSPER               DIWS          G FP+L+   +   P +  L+ AI    PP+ P
Sbjct:   65 ITAEDLETVKVIGKGSGGVVQLVRHKWVGKFFAMKVIQMNIQEEIRKQIVQELKINQASSQCPHVVVCYHSFYH-NGAFSLVLEYMDRGSLADVIRQVKTILEPYLAVVCKQVLLGLVYLHNERHVIHRDIKPSNLLVNHKG-EVKISDFGVSASLASSMGQRDTFVGTYNYMSPERIS-----GSTYDYSSDIWSLGMSVLECAIGRFPYLESEDQQNPPSFYELLAAIVENPPPTAP 296          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: MEK2_CAEEL (Dual specificity mitogen-activated protein kinase kinase mek-2 OS=Caenorhabditis elegans GN=mek-2 PE=1 SV=1)

HSP 1 Score: 150.599 bits (379), Expect = 1.049e-35
Identity = 88/211 (41.71%), Postives = 127/211 (60.19%), Query Frame = 3

Query:  180 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGH-KIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQPGQRPDWATL 809
            LGHGNGG V K  HR T  I A K+VH +  P+VR+Q+ +E+ +L + +SPFIV  +G F   + DI+I MEYMD  +LD +L K G   E  +  ++  +++GL+YL    KI+HRD+KPSN+LVN+N  ++K+ DFGVS ++  S+   NS+VGT +YM+PER               DIWS          G +P   P Q  ++AT+
Sbjct:   79 LGHGNGGVVNKCVHRKTGVIMARKLVHLEIKPSVRQQIVKELAVLHKCNSPFIVGFYGAF-VDNNDISICMEYMDGLSLDIVLKKVGRLPEKFVGRISVAVVRGLTYLKDEIKILHRDVKPSNMLVNSNG-EIKLCDFGVSGMLIDSM--ANSFVGTRSYMAPERL-----TGSHYTISSDIWSFGLSLVELLIGRYPVPAPSQ-AEYATM 279          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: MP2K2_CHICK (Dual specificity mitogen-activated protein kinase kinase 2 OS=Gallus gallus GN=MAP2K2 PE=2 SV=1)

HSP 1 Score: 150.214 bits (378), Expect = 1.370e-35
Identity = 84/212 (39.62%), Postives = 124/212 (58.49%), Query Frame = 3

Query:  159 DLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYL-HGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQPGQR 791
            D E++  LG GNGG V KVQH+ +  I A K++H +  P +R Q+ RE+++L   +SP+IV  +G F    G+I+I ME+MD G+LD +L +     E  L  ++  +L+GL+YL   H+I+HRD+KPSN+LVN+   ++K+ DFGVS  +  S+   NS+VGT +YMSPER               DIWS          G +P   P  +
Sbjct:   69 DFERISELGAGNGGVVTKVQHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSM--ANSFVGTRSYMSPERLQ-----GTHYSVQSDIWSMGLSLVELSIGRYPIPPPDSK 271          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: MP2K2_HUMAN (Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens GN=MAP2K2 PE=1 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 1.789e-35
Identity = 84/209 (40.19%), Postives = 123/209 (58.85%), Query Frame = 3

Query:  159 DLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYL-HGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQP 782
            D E++  LG GNGG V KVQHR +  I A K++H +  P +R Q+ RE+++L   +SP+IV  +G F    G+I+I ME+MD G+LD +L +     E  L  ++  +L+GL+YL   H+I+HRD+KPSN+LVN+   ++K+ DFGVS  +  S+   NS+VGT +YM+PER               DIWS          G +P   P
Sbjct:   71 DFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSM--ANSFVGTRSYMAPERLQ-----GTHYSVQSDIWSMGLSLVELAVGRYPIPPP 270          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: MP2K2_RAT (Dual specificity mitogen-activated protein kinase kinase 2 OS=Rattus norvegicus GN=Map2k2 PE=2 SV=1)

HSP 1 Score: 148.288 bits (373), Expect = 5.205e-35
Identity = 84/209 (40.19%), Postives = 122/209 (58.37%), Query Frame = 3

Query:  159 DLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYL-HGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQP 782
            D E++  LG GNGG V K +HR +  I A K++H +  P VR Q+ RE+++L   +SP+IV  +G F    G+I+I ME+MD G+LD +L +     E  L  ++  +L+GL+YL   H+I+HRD+KPSN+LVN+   ++K+ DFGVS  +  S+   NS+VGT +YMSPER               DIWS          G +P   P
Sbjct:   71 DFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYS-DGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRG-EIKLCDFGVSGQLIDSM--ANSFVGTRSYMSPERLQ-----GTHYSVQSDIWSMGLSLVELAIGRYPIPPP 270