CX672514

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: CC2H3_TRYBB (Cell division control protein 2 homolog 3 OS=Trypanosoma brucei brucei GN=CRK3 PE=3 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 1.245e-20
Identity = 59/168 (35.12%), Postives = 90/168 (53.57%), Query Frame = 3

Query:  168 KLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGD-ADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPE 668
            ++ +LG G  G VY+   R T +I ALK V  D  D  + +   RE+ IL+    P IV    +     G + ++ EY+D      L  + G F+   L  +  Q+L+GLS+ H H+I+HRD+KP+N+LV  +N  VKIADFG+++     +      V T  Y +PE
Sbjct:   25 RMDILGEGTYGVVYRAVDRATGQIVALKKVRLDRTDEGIPQTALREVSILQEIHHPNIVNLLDVI-CADGKLYLIFEYVDHDLKKALEKRGGAFTGTTLKKIIYQLLEGLSFCHRHRIVHRDLKPANILVTTDN-SVKIADFGLARAFQIPMHTYTHEVVTLWYRAPE 190          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: STK4_XENTR (Serine/threonine-protein kinase 4 OS=Xenopus tropicalis GN=stk4 PE=2 SV=1)

HSP 1 Score: 99.7525 bits (247), Expect = 2.123e-20
Identity = 57/167 (34.13%), Postives = 102/167 (61.08%), Query Frame = 3

Query:  171 LQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLN-KNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPE 668
            L+ LG G+ G+VYK  H+ T +I A+K +  ++D    +++ +E+ I+++ DS  +V+ +G + K + D+ I+ME+   G++  ++  +  T  E + A +    LKGL YLH  + IHRDIK  N+L+N+     K+ADFGV+  +  ++   N+ +GT  +M+PE
Sbjct:   33 LEKLGEGSYGSVYKASHKETSQIVAIKQIPVESD---LQEIIKEIAIMQQCDSLHVVKYYGSYFKNT-DLWIVMEFCGGGSISDIIRLRKQTLKEDETATILQSTLKGLEYLHFMRKIHRDIKAGNILLNSEG-TAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPE 194          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: CST1_CAEEL (Serine/threonine-protein kinase cst-1 OS=Caenorhabditis elegans GN=cst-1 PE=2 SV=1)

HSP 1 Score: 99.7525 bits (247), Expect = 2.123e-20
Identity = 63/199 (31.66%), Postives = 109/199 (54.77%), Query Frame = 3

Query:  180 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLN-KNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPF 773
            LG G+ G+V+K  HR +  + A+K V  D D    +++ +E+ I+++  S ++V+ +G + K S D+ I+MEY  +G++  ++  +    SE +++ +    LKGL YLH  K IHRDIK  N+L+N + +  K+ADFGV+  +  ++   N+ +GT  +M+PE  +             DIWS          G  P+
Sbjct:   41 LGEGSYGSVHKAIHRESGHVLAIKKVPVDTD---LQEIIKEISIMQQCKSKYVVKYYGSYFKHS-DLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGI-AKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIE-----EIGYDTKADIWSLGITAIEMAEGRPPY 229          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: SVKA_DICDI (Serine/threonine-protein kinase svkA OS=Dictyostelium discoideum GN=svkA PE=1 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 2.773e-20
Identity = 63/174 (36.21%), Postives = 104/174 (59.77%), Query Frame = 3

Query:  159 DLEKLQV----LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPE 668
            D E+L V    +G G+ G V+K  ++ T++  A+K +  +        + +E+ +L + +SPF+ + FG F K S  + I+MEY+  G++  L+ K G F E  +A +  ++LKGL YLH    IHRDIK +N+L++ +   VK+ADFGVS  +   +   N++VGT  +M+PE
Sbjct:    7 DPEELYVRQEKIGKGSFGEVFKGINKKTNETIAIKTIDLEDAEDEIEDIQQEINVLSQCESPFVTKYFGSFLKGS-KLWIIMEYLAGGSVLDLM-KPGPFDEGYIAIILRELLKGLEYLHSEGKIHRDIKAANVLLSASG-DVKLADFGVSGQLTDQMTKRNTFVGTPFWMAPE 177          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: M4K4_HUMAN (Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens GN=MAP4K4 PE=1 SV=2)

HSP 1 Score: 99.3673 bits (246), Expect = 2.773e-20
Identity = 63/196 (32.14%), Postives = 110/196 (56.12%), Query Frame = 3

Query:  165 EKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRR-TDSPFIVQCFGIFEKPS-----GDIAILMEYMDSGTLDTLLN--KNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWS 728
            E ++V+G+G  G VYK +H  T ++ A+KV+  D       ++  E+ +L++ +    I   +G F K S       + ++ME+  +G++  L+   K  T  E  +A+++ +IL+GL++LH H +IHRDIK  N+L+   N +VK+ DFGVS  + R++   N+++GT  +M+PE    D           D+WS
Sbjct:   26 ELVEVVGNGTYGQVYKGRHVKTGQLAAIKVM--DVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLL-TENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWS 218          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: PPK11_SCHPO (Serine/threonine-protein kinase ppk11 OS=Schizosaccharomyces pombe GN=ppk11 PE=2 SV=1)

HSP 1 Score: 98.9821 bits (245), Expect = 3.621e-20
Identity = 64/166 (38.55%), Postives = 95/166 (57.23%), Query Frame = 3

Query:  171 LQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPE 668
            LQ++G G+ G+V++ Q   + KI ALKVV  DA       + +E+  L   +S  I + +  F      + I MEY D G+   LL  +GTFSE  +A +  Q+L+ L YLHG   +HRDIK +N+L   + + VK+ADFGVS  +    D  + +VGT  +M+PE
Sbjct:    9 LQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDLNSVHITKYYASFVD-GFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMKDGL-VKLADFGVSGQLESLRDKNDDFVGTPFWMAPE 172          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: STK4L_DICDI (Serine/threonine-protein kinase 4 homolog B OS=Dictyostelium discoideum GN=krsB PE=3 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 4.730e-20
Identity = 58/171 (33.92%), Postives = 101/171 (59.06%), Query Frame = 3

Query:  159 DLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLN-KNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPE 668
            + + ++ LG G+ G+VYK  ++ T  I A+K+V  + D    +++ +E+ I+++  S ++VQ +G + K      I+MEY   G++  ++N  N   +E ++A +    LKGL YLH +  IHRDIKP N+LV+    + K+ADFGVS  +       N+ +GT  +++PE
Sbjct:   22 EFDLIECLGRGSFGSVYKATYKKTGNIVAVKLVPINED---FQEILKEINIMKQCKSKYVVQYYGNYFKDE-TCWIIMEYCAFGSVSDMMNITNRVLNEEQIALVCYSTLKGLYYLHRNSKIHRDIKPGNILVSEEG-ECKLADFGVSGQLSERTRKRNTVIGTPFFLAPE 187          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: SIK2_HUMAN (Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 4.730e-20
Identity = 65/213 (30.52%), Postives = 104/213 (48.83%), Query Frame = 3

Query:  147 IAYSDLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVH-GDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQP 782
            + + D+E    LG GN   V   +HR T    A+K++     D     +++RE++I++  D P I++ + + E  S  + ++ EY  +G +   L  +G  +E +      QIL  + Y HG KI+HRD+K  NLL+ +NNM +KIADFG      +S +   ++ G+  Y +PE F+             DIWS          G  PF  P
Sbjct:   17 VGFYDIEG--TLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSM-LYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLL-DNNMNIKIADFGFGNFF-KSGELLATWCGSPPYAAPEVFE----GQQYEGPQLDIWSMGVVLYVLVCGALPFDGP 220          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: MP2K6_HUMAN (Dual specificity mitogen-activated protein kinase kinase 6 OS=Homo sapiens GN=MAP2K6 PE=1 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 4.730e-20
Identity = 72/211 (34.12%), Postives = 110/211 (52.13%), Query Frame = 3

Query:  159 DLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRT-DSPFIVQCFGIFEKPSGDIAILMEYMDSGTLD----TLLNKNGTFSEPKLAHMASQILKGLSYLHGH-KIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPF 773
            DLE +  LG G  G V K++H  + +I A+K +    +   ++++  +++I  RT D PF V  +G   +  GD+ I ME MD+ +LD     +++K  T  E  L  +A  I+K L +LH    +IHRD+KPSN+L+N    QVK+ DFG+S  +  S+ A     G   YM+PER +P+           DIWS            FP+
Sbjct:   52 DLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFR-EGDVWICMELMDT-SLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALG-QVKMCDFGISGYLVDSV-AKTIDAGCKPYMAPERINPE-LNQKGYSVKSDIWSLGITMIELAILRFPY 257          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: MP2K6_BOVIN (Dual specificity mitogen-activated protein kinase kinase 6 OS=Bos taurus GN=MAP2K6 PE=2 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 4.730e-20
Identity = 72/211 (34.12%), Postives = 110/211 (52.13%), Query Frame = 3

Query:  159 DLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRT-DSPFIVQCFGIFEKPSGDIAILMEYMDSGTLD----TLLNKNGTFSEPKLAHMASQILKGLSYLHGH-KIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPF 773
            DLE +  LG G  G V K++H  + +I A+K +    +   ++++  +++I  RT D PF V  +G   +  GD+ I ME MD+ +LD     +++K  T  E  L  +A  I+K L +LH    +IHRD+KPSN+L+N    QVK+ DFG+S  +  S+ A     G   YM+PER +P+           DIWS            FP+
Sbjct:   52 DLEPIVELGRGAYGVVEKMRHVPSEQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFR-EGDVWICMELMDT-SLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALG-QVKMCDFGISGYLVDSV-AKTIDAGCKPYMAPERINPE-LNQKGYSVKSDIWSLGITMIELAILRFPY 257