CX672514

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: SCH9_YEAST (Serine/threonine-protein kinase SCH9 OS=Saccharomyces cerevisiae GN=SCH9 PE=1 SV=3)

HSP 1 Score: 96.6709 bits (239), Expect = 1.797e-19
Identity = 61/175 (34.86%), Postives = 96/175 (54.86%), Query Frame = 3

Query:  159 DLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRR--QVFREMEILRRT---DSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPE 668
            D E L++LG G  G VY+V+ + T +IYA+KV+                E  IL  T    SPFIV     F+ P+ D+ ++ +YM  G L   L K G FSE +     ++++  L +LH + I++RD+KP N+L++ N   + + DFG+SK   +  D  N++ GT  Y++PE
Sbjct:  411 DFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPT-DLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANG-NIALCDFGLSKADLK--DRTNTFCGTTEYLAPE 581          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: MP2K4_MOUSE (Dual specificity mitogen-activated protein kinase kinase 4 OS=Mus musculus GN=Map2k4 PE=1 SV=2)

HSP 1 Score: 96.6709 bits (239), Expect = 1.797e-19
Identity = 74/239 (30.96%), Postives = 118/239 (49.37%), Query Frame = 3

Query:  159 DLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEI-LRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNK-----NGTFSEPKLAHMASQILKGLSYLHGH-KIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQPGQRPDWATL---MCAICFGDPPSL 845
            DL+ L  +G G  G+V K+ H+ + +I A+K +    D   ++Q+  ++++ +R +D P+IVQ +G   +  GD  I ME M S + D          +    E  L  +    +K L++L  + KIIHRDIKPSN+L++ +   +K+ DFG+S  +  S+ A     G   YM+PER DP            D+WS          G FP+      P W ++   +  +  GDPP L
Sbjct:   99 DLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFR-EGDCWICMELM-STSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSG-NIKLCDFGISGQLVDSI-AKTRDAGCRPYMAPERIDPS-ASRQGYDVRSDVWSLGITLYELATGRFPY------PKWNSVFDQLTQVVKGDPPQL 326          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: MP2K4_HUMAN (Dual specificity mitogen-activated protein kinase kinase 4 OS=Homo sapiens GN=MAP2K4 PE=1 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 1.797e-19
Identity = 74/239 (30.96%), Postives = 118/239 (49.37%), Query Frame = 3

Query:  159 DLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEI-LRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNK-----NGTFSEPKLAHMASQILKGLSYLHGH-KIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQPGQRPDWATL---MCAICFGDPPSL 845
            DL+ L  +G G  G+V K+ H+ + +I A+K +    D   ++Q+  ++++ +R +D P+IVQ +G   +  GD  I ME M S + D          +    E  L  +    +K L++L  + KIIHRDIKPSN+L++ +   +K+ DFG+S  +  S+ A     G   YM+PER DP            D+WS          G FP+      P W ++   +  +  GDPP L
Sbjct:  101 DLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFR-EGDCWICMELM-STSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSG-NIKLCDFGISGQLVDSI-AKTRDAGCRPYMAPERIDPS-ASRQGYDVRSDVWSLGITLYELATGRFPY------PKWNSVFDQLTQVVKGDPPQL 328          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: DST2_DICDI (Serine/threonine-protein kinase dst2 OS=Dictyostelium discoideum GN=dst2 PE=3 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 1.797e-19
Identity = 64/189 (33.86%), Postives = 107/189 (56.61%), Query Frame = 3

Query:  165 EKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNK-NGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWS 728
            E ++ +  G+ GTVYK +H  T  I A+K++  D D T    V  E++IL R +   IV+ +G + K   ++ I ME    G++  +  + N   +E ++A++  + LKGL YLH   +IHRD+K +N+L+  +   VK+ADFGVS ++ +S    N+++GT  +M+PE  + +           DIWS
Sbjct:   21 ELIEEIAEGSFGTVYKGKHLPTGNIMAVKIIALDEDETFEDLVV-EIDILNRCNHNNIVKYYGSWVK-GDELFIAMECCGGGSITEIYQELNIPLNESQIAYVCRETLKGLEYLHHTNVIHRDLKGANILLTESG-DVKLADFGVSGLLDKS-SKRNTFIGTPYWMAPEVIE-NRSNPVPYDTKADIWS 204          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: CDS1_SCHPO (Serine/threonine-protein kinase cds1 OS=Schizosaccharomyces pombe GN=cds1 PE=1 SV=2)

HSP 1 Score: 96.2857 bits (238), Expect = 2.347e-19
Identity = 63/218 (28.90%), Postives = 102/218 (46.79%), Query Frame = 3

Query:  156 SDLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHG------DADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERF-DPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQPGQ 788
            S  E ++ LG G    V       + K YA+K+++        ++        RE++IL+    P +VQC  IFE    ++ I+MEY++ G L   L  NG+  E     +  Q+L+ L +LH   + HRDIKP N+L+  N+  +KI+DFG++K++  +     ++ GT  Y++PE     +           DIWS             PF    Q
Sbjct:  165 SHYEIIRTLGSGTFAVVKLAVEVNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSLHHPGVVQCHEIFENDD-ELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILI-TNDFHLKISDFGLAKVIHGTGTFLETFCGTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFASSSQ 380          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: PAKE_DICDI (Serine/threonine-protein kinase pakE OS=Dictyostelium discoideum GN=pakE PE=3 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 3.066e-19
Identity = 54/164 (32.93%), Postives = 94/164 (57.32%), Query Frame = 3

Query:  180 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKN-GTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPE 668
            LG G  G V+KV HR T+   A+KV+     PT  + + +E+++L++   P ++  +G       ++ ILM++   G+++ ++     T  E ++A +   +L GL YLH   I+H D+K +N+L+  +  Q+KIADFGVS+ +       N Y+G+  YM+PE
Sbjct:  656 LGQGGYGAVFKVLHRETNFPLAIKVL--SITPTRIKDIEKEIDLLKKCRCPNVLSYYGSISSKLTELWILMDHCAVGSINDMMKICCDTLDEEQIAVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDK-QIKIADFGVSQQLQTEYGQANVYIGSPLYMAPE 816          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: IPL1_YEAST (Spindle assembly checkpoint kinase OS=Saccharomyces cerevisiae GN=IPL1 PE=1 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 3.066e-19
Identity = 63/176 (35.80%), Postives = 96/176 (54.55%), Query Frame = 3

Query:  147 IAYSDLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDA--DPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPE 668
            ++  D E  + LG G  G VY V+HR T  I ALKV+  +      +++Q  RE+EI    + P + + +G F      + +LMEY+ +G +  LL  +G F++   +    QI   L Y+H   IIHRDIKP N+L+  NN+ +K+ DFG S I+    +   +  GT  Y+SPE
Sbjct:   99 LSLDDFELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKR-VYLLMEYLVNGEMYKLLRLHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNV-IKLTDFGWS-IINPPENRRKTVCGTIDYLSPE 271          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: SIK2_PONAB (Serine/threonine-protein kinase SIK2 OS=Pongo abelii GN=SIK2 PE=2 SV=1)

HSP 1 Score: 95.5153 bits (236), Expect = 4.004e-19
Identity = 64/213 (30.05%), Postives = 103/213 (48.36%), Query Frame = 3

Query:  147 IAYSDLEKLQVLGHGNGGTVYKVQHRCTHKIYALKVVH-GDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWSXXXXXXXXXXGHFPFLQP 782
            + + D+E    LG GN   V   +HR T    A+K++     D     +++RE++I++  D P I++ + + E  S  + ++ EY  +G +   L  +G  +E +      QIL  + Y HG KI+HRD+K  NLL+ +NNM +KIADF       +S +   ++ G+  Y +PE F+             DIWS          G  PF  P
Sbjct:   17 VGFYDIEG--TLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSM-LYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLL-DNNMNIKIADFSFGNFF-KSGELLATWRGSPPYAAPEVFE----GQQYEGPQLDIWSMGVVLYVLVCGALPFDGP 220          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: SID1_SCHPO (Serine/threonine-protein kinase sid1 OS=Schizosaccharomyces pombe GN=sid1 PE=1 SV=1)

HSP 1 Score: 95.5153 bits (236), Expect = 4.004e-19
Identity = 56/166 (33.73%), Postives = 98/166 (59.04%), Query Frame = 3

Query:  171 LQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPE 668
            L+ LG G+ G V+K +   +  I A+K +  +        + +E+ +L   +S  ++Q +G F      + ILME+MD G++  LL K G  +E  ++ +  ++L GL+YLHG   IHRDIK +N+L++++   VK+ADFGV+  +  +    +++VGT  +M+PE
Sbjct:   12 LRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCNSSNVIQYYGCFVD-GYTLWILMEHMDGGSVSGLL-KMGRLNEQVISIILREVLYGLNYLHGQNKIHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPE 175          

BLAST of CX672514 vs. ExPASy Swiss-Prot
Match: DST4_DICDI (Serine/threonine-protein kinase dst4 OS=Dictyostelium discoideum GN=dst4 PE=3 SV=1)

HSP 1 Score: 95.5153 bits (236), Expect = 4.004e-19
Identity = 66/188 (35.11%), Postives = 106/188 (56.38%), Query Frame = 3

Query:  171 LQVLGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRT-DSPFIVQCFGIFEKPSGDIAILMEYMDSGT-LDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXXDIWS 728
            L+V+G G+ G V    +   +++ A+K +  + +      + +E+ IL+ T   P+IV+  G + K + ++ I+MEY D G+ LD +   + T +E ++A +  QI++GL YLH +KI+HRDIK  N+LVN    Q K+ADFGVS I+  +     + VG+  +MSPE   P            DIWS
Sbjct:   24 LEVIGQGSFGVVCTCINTVNNEVVAIKFLEMEGEEN--SSLKKEITILKNTVRCPYIVKYHGCYIKEN-NLMIVMEYCDGGSILDIMQMCSITLTEAQIAAILYQIVEGLVYLHSNKILHRDIKAGNVLVNKLG-QAKLADFGVSAILVNTGFKQKTVVGSPYWMSPEVISP-PKGSNGYDSKADIWS 206