CX672513

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: MP2K3_HUMAN (Dual specificity mitogen-activated protein kinase kinase 3 OS=Homo sapiens GN=MAP2K3 PE=1 SV=2)

HSP 1 Score: 110.923 bits (276), Expect = 1.092e-23
Identity = 89/276 (32.25%), Postives = 138/276 (50.00%), Query Frame = -2

Query:  160 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRT-DSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDT----LLNKNGTFSEPKLAHMASQILKGLSYLHGH-KIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWAT---LMCAICFGDPPSLP-DGASPEFRSFIECCLQKEFSKRWTASQLLTHPF--LCKNRRSD 951
            LG G  G V KV+H  +  I A+K +    +   ++++  +++I  RT D  + V  +G   +  GD+ I ME MD+ +LD     +L+KN T  E  L  +A  I++ L +LH    +IHRD+KPSN+L+N     VK+ DFG+S  +  S+ A     G   YM+PER +P+           D+WS         +  FP+        W T    +  +     P LP D  SPEF  F   CL+K  ++R +  +L+ HPF  L K +++D
Sbjct:   70 LGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALFR-EGDVWICMELMDT-SLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEG-HVKMCDFGISGYLVDSV-AKTMDAGCKPYMAPERINPELNQKGYNVKS-DVWSLGITMIEMAILRFPY------ESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTD 334          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: MP2K6_HUMAN (Dual specificity mitogen-activated protein kinase kinase 6 OS=Homo sapiens GN=MAP2K6 PE=1 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 1.426e-23
Identity = 88/266 (33.08%), Postives = 132/266 (49.62%), Query Frame = -2

Query:  184 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRT-DSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDT----LLNKNGTFSEPKLAHMASQILKGLSYLHGH-KIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWAT---LMCAICFGDPPSLP-DGASPEFRSFIECCLQKEFSKRWTASQLLTHPF 951
            LG G  G V K++H  + +I A+K +    +   ++++  +++I  RT D PF V  +G   +  GD+ I ME MD+ +LD     +++K  T  E  L  +A  I+K L +LH    +IHRD+KPSN+L+N    QVK+ DFG+S  +  S+ A     G   YM+PER +P+           DIWS         +  FP+        W T    +  +     P LP D  S EF  F   CL+K   +R T  +L+ HPF
Sbjct:   59 LGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFR-EGDVWICMELMDT-SLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALG-QVKMCDFGISGYLVDSV-AKTIDAGCKPYMAPERINPE-LNQKGYSVKSDIWSLGITMIELAILRFPY------DSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPF 313          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: M4K4_MOUSE (Mitogen-activated protein kinase kinase kinase kinase 4 OS=Mus musculus GN=Map4k4 PE=1 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 1.862e-23
Identity = 85/266 (31.95%), Postives = 134/266 (50.38%), Query Frame = -2

Query:  181 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRR-TDSPFIVQCFGIFEKPS-----GDIAILMEYMDSGTLDTLLN--KNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSLPDGA-SPEFRSFIECCLQKEFSKRWTASQLLTHPFL 951
            +G+G  G VYK +H  T    A+KV+  D       ++  E+ +L++ +    I   +G F K S       + ++ME+  +G++  L+   K  T  E  +A+++ +IL+GL++LH H +IHRDIK  N+L+   N +VK+ DFGVS  + R++   N+++GT  +M+PE    D           D+WS          G  P       P  A  +  I    PP L     S +F SFIE CL K + +R +  QLL HPF+
Sbjct:   31 VGNGTYGQVYKGRHVKTVTA-AIKVM--DVTEDEEEEITLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLL-TENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGGPPLCD--MHPMRALFL--IPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFI 288          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: MP2K6_MOUSE (Dual specificity mitogen-activated protein kinase kinase 6 OS=Mus musculus GN=Map2k6 PE=2 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 2.432e-23
Identity = 86/266 (32.33%), Postives = 132/266 (49.62%), Query Frame = -2

Query:  184 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRT-DSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDT----LLNKNGTFSEPKLAHMASQILKGLSYLHGH-KIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWAT---LMCAICFGDPPSLP-DGASPEFRSFIECCLQKEFSKRWTASQLLTHPF 951
            LG G  G V K++H  + +I A+K +    +   ++++  ++++  RT D PF V  +G   +  GD+ I ME MD+ +LD     +++K  T  E  L  +A  I+K L +LH    +IHRD+KPSN+L+N    QVK+ DFG+S  +  S+ A     G   YM+PER +P+           DIWS         +  FP+        W T    +  +     P LP D  S +F  F   CL+K   +R T  +L+ HPF
Sbjct:   59 LGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALFR-EGDVWICMELMDT-SLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINTLG-QVKMCDFGISGYLVDSV-AKTIDAGCKPYMAPERINPE-LNQKGYSVKSDIWSLGITMIELAILRFPY------DSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSKERPTYPELMQHPF 313          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: Y4251_DICDI (Probable serine/threonine-protein kinase DDB_G0284251 OS=Dictyostelium discoideum GN=DDB_G0284251 PE=3 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 4.148e-23
Identity = 80/258 (31.01%), Postives = 127/258 (49.22%), Query Frame = -2

Query:  187 LGHGNGGTVYKVQHRCTHKIYALKVVHGDA-DPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPF--LQPGQRPDWATLMCAICFGDPPSLPDGASPEFRSFIECCLQKEFSKRWTASQLLTHP 951
            +G G  G V+K  +  T +  A+K +  +  D +  + V  E+EIL +     IV+  G+ E  +  +  ++EY+++G+L  ++ K G  SE        Q+L+GL+YLH +K+IHRDIK SN+L+    + +K+ADFGV+  +        S VGT  +M+PE  +             DIWS          G+ P+  LQP         M  I     P  P   S EF  + +   +K+ ++R TA +LL HP
Sbjct:   42 IGRGAFGQVFKGLNGKTGEFVAIKQIDSNKIDESSLQSVKGEVEILHKLRHNNIVKVLGVVEVQA-QLNFILEYVENGSLRDVIEKFGPLSEELCIIYLYQMLQGLAYLHSNKVIHRDIKASNILITKEGV-IKLADFGVASQIDSESQLRFSVVGTPYWMAPESIE-----ISGCSSASDIWSLGSTMIELLTGNPPYYTLQP------MAAMFRIVSDQHPPFPTDISKEFLDYFQQSFKKDPTQRPTAQELLQHP 286          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: STK36_HUMAN (Serine/threonine-protein kinase 36 OS=Homo sapiens GN=STK36 PE=1 SV=2)

HSP 1 Score: 108.997 bits (271), Expect = 4.148e-23
Identity = 76/259 (29.34%), Postives = 128/259 (49.42%), Query Frame = -2

Query:  181 LGHGNGGTVYKVQHRCTHKIYALKVVH--GDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSLPDGASPEFRSFIECCLQKEFSKRWTASQLLTHPFL 951
            +G G+ G VYK + + + ++ ALK +   G ++  +R  + RE+EI+R    P IV     FE    ++ ++ +Y + G L  +L  +G   E ++  +A+Q++  L YLH H+I+HRD+KP N+L+      +K+ DFG ++ M  +     S  GT  YMSPE  +             D+WS         +G  PF            + ++   DP   P   SP F++F++  L K+  +R +   LL HPF+
Sbjct:   10 IGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLRHPNIVHMLDSFETDK-EVVVVTDYAE-GELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGG-GIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVE-----ERPYDHTADLWSVGCILYELAVGTPPFYATS-----IFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFI 254          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: PPK11_SCHPO (Serine/threonine-protein kinase ppk11 OS=Schizosaccharomyces pombe GN=ppk11 PE=2 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 4.148e-23
Identity = 88/260 (33.85%), Postives = 124/260 (47.69%), Query Frame = -2

Query:  175 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSLPDGA-SPEFRSFIECCLQKEFSKRWTASQLLTHPFLCK 951
            +G G+ G+V++ Q   + KI ALKVV  DA       + +E+  L   +S  I + +  F      + I MEY D G+   LL  +GTFSE  +A +  Q+L+ L YLHG   +HRDIK +N+L   + + VK+ADFGVS  +    D  + +VGT  +M+PE                DIWS          G  P+   G  P    ++  I    PPSL     S  F  F+  CL+K    R TA  L  H F+ K
Sbjct:   12 IGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDLNSVHITKYYASFVD-GFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMKDGL-VKLADFGVSGQLESLRDKNDDFVGTPFWMAPE-----VVKQTGYNYKADIWSLGITAYELATGEPPY--SGIHP--MKVLLLIPKHSPPSLERSKFSRAFCDFVSNCLKKNPKDRATAEYLSKHKFIKK 260          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: STK36_PONAB (Serine/threonine-protein kinase 36 OS=Pongo abelii GN=STK36 PE=2 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 5.418e-23
Identity = 76/259 (29.34%), Postives = 128/259 (49.42%), Query Frame = -2

Query:  181 LGHGNGGTVYKVQHRCTHKIYALKVVH--GDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSLPDGASPEFRSFIECCLQKEFSKRWTASQLLTHPFL 951
            +G G+ G VYK + + + ++ ALK +   G ++  +R  + RE+EI+R    P IV     FE    ++ ++ +Y + G L  +L  +G   E ++  +A+Q++  L YLH H+I+HRD+KP N+L+      +K+ DFG ++ M  +     S  GT  YMSPE  +             D+WS         +G  PF            + ++   DP   P   SP F++F++  L K+  +R +   LL HPF+
Sbjct:   10 IGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRN-LQREIEIMRGLRHPNIVHMLDSFETDK-EVVVVTDYAE-GELLQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGG-GIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVE-----ERPYDHTADLWSVGCILYELAVGTPPFYATS-----IFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFI 254          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: PAKE_DICDI (Serine/threonine-protein kinase pakE OS=Dictyostelium discoideum GN=pakE PE=3 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 5.418e-23
Identity = 81/266 (30.45%), Postives = 131/266 (49.25%), Query Frame = -2

Query:  163 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKN-GTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSL--PDGASPEFRSFIECCLQKEFSKRWTASQLLTHPFLCKNRRS 951
            LG G  G V+KV HR T+   A+KV+     PT  + + +E+++L++   P ++  +G       ++ ILM++   G+++ ++     T  E ++A +   +L GL YLH   I+H D+K +N+L+  +  Q+KIADFGVS+ +       N Y+G+  YM+PE                DIWS          G  P    G R      +  I    PP L  P   SP F +F+  CL K+  +R +   LL+H F+ KN ++
Sbjct:  656 LGQGGYGAVFKVLHRETNFPLAIKVL--SITPTRIKDIEKEIDLLKKCRCPNVLSYYGSISSKLTELWILMDHCAVGSINDMMKICCDTLDEEQIAVVTLNVLNGLGYLHSKGIVHLDVKAANILLTEDK-QIKIADFGVSQQLQTEYGQANVYIGSPLYMAPE-----VILKAPYNSKADIWSLGITLIELAEGRPP--NRGLRS--MNQLVEIPNMPPPKLSNPKDWSPCFNNFLATCLVKDPVQRPSVIDLLSHDFI-KNAKT 908          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: MP2K3_MOUSE (Dual specificity mitogen-activated protein kinase kinase 3 OS=Mus musculus GN=Map2k3 PE=1 SV=2)

HSP 1 Score: 108.612 bits (270), Expect = 5.418e-23
Identity = 88/276 (31.88%), Postives = 136/276 (49.28%), Query Frame = -2

Query:  160 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRT-DSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDT----LLNKNGTFSEPKLAHMASQILKGLSYLHGH-KIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWAT---LMCAICFGDPPSLP-DGASPEFRSFIECCLQKEFSKRWTASQLLTHPF--LCKNRRSD 951
            LG G  G V KV+H  +  I A+K +    +   ++++  +++I  RT D  + V  +G   +  GD+ I ME MD+ +LD     +L KN    E  L  +A  I++ L +LH    +IHRD+KPSN+L+N     VK+ DFG+S  +  S+ A     G   YM+PER +P+           D+WS         +  FP+        W T    +  +     P LP D  SPEF  F   CL+K  ++R +  +L+ HPF  L K +++D
Sbjct:   70 LGRGAYGVVEKVRHAQSGTIMAVKRIRATVNTQEQKRLLMDLDINMRTVDCFYTVTFYGALFR-EGDVWICMELMDT-SLDKFYRKVLEKNMKIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEG-HVKMCDFGISGYLVDSV-AKTMDAGCKPYMAPERINPELNQKGYNVKS-DVWSLGITMIEMAILRFPY------ESWGTPFQQLKQVVEEPSPQLPADQFSPEFVDFTSQCLRKNPAERMSYLELMEHPFFTLHKTKKTD 334