CX672513

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: SLK_RAT (STE20-like serine/threonine-protein kinase OS=Rattus norvegicus GN=Slk PE=1 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 4.009e-26
Identity = 81/260 (31.15%), Postives = 131/260 (50.38%), Query Frame = -2

Query:  181 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDT-LLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSL--PDGASPEFRSFIECCLQKEFSKRWTASQLLTHPFL 951
            LG G  G VYK Q++ T+ + A KV+   ++  +   +  E++IL   D P IV+    F   + ++ IL+E+   G +D  +L      +E ++  +  Q L+ L+YLH +KIIHRD+K  N+L   +   +K+ADFGVS    R++   +S++GT  +M+PE    +           D+WS                 P    +   ++  I   +PP+L  P   S  F+ F++ CL+K    RWT SQLL HPF+
Sbjct:   40 LGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMV-EIDILASCDHPNIVKLLDAFYYEN-NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDG-DIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE----IEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFV 292          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: SLK_CAVPO (STE20-like serine/threonine-protein kinase OS=Cavia porcellus GN=SLK PE=1 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 4.009e-26
Identity = 81/260 (31.15%), Postives = 131/260 (50.38%), Query Frame = -2

Query:  181 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDT-LLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSL--PDGASPEFRSFIECCLQKEFSKRWTASQLLTHPFL 951
            LG G  G VYK Q++ T+ + A KV+   ++  +   +  E++IL   D P IV+    F   + ++ IL+E+   G +D  +L      +E ++  +  Q L+ L+YLH +KIIHRD+K  N+L   +   +K+ADFGVS    R++   +S++GT  +M+PE    +           D+WS                 P    +   ++  I   +PP+L  P   S  F+ F++ CL+K    RWT SQLL HPF+
Sbjct:   40 LGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMV-EIDILASCDHPNIVKLLDAFYYEN-NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDG-DIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE----IEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFV 292          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: TNIK_MOUSE (Traf2 and NCK-interacting protein kinase OS=Mus musculus GN=Tnik PE=1 SV=2)

HSP 1 Score: 118.627 bits (296), Expect = 5.235e-26
Identity = 87/266 (32.71%), Postives = 137/266 (51.50%), Query Frame = -2

Query:  181 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRR-TDSPFIVQCFGIFEK--PSG---DIAILMEYMDSGTLDTLLN--KNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSLPDGA-SPEFRSFIECCLQKEFSKRWTASQLLTHPFL 951
            +G+G  G VYK +H  T ++ A+KV+    D     ++ +E+ +L++ +    I   +G F K  P G    + ++ME+  +G++  L+   K  T  E  +A++  +IL+GLS+LH HK+IHRDIK  N+L+   N +VK+ DFGVS  + R++   N+++GT  +M+PE    D           D+WS          G  P       P  A  +  I     P L     S +F+SFIE CL K  S+R    QL+ HPF+
Sbjct:   31 VGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDE--EEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLL-TENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCD--MHPMRALFL--IPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFI 289          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: TNIK_HUMAN (TRAF2 and NCK-interacting protein kinase OS=Homo sapiens GN=TNIK PE=1 SV=1)

HSP 1 Score: 118.627 bits (296), Expect = 5.235e-26
Identity = 87/266 (32.71%), Postives = 137/266 (51.50%), Query Frame = -2

Query:  181 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRR-TDSPFIVQCFGIFEK--PSG---DIAILMEYMDSGTLDTLLN--KNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSLPDGA-SPEFRSFIECCLQKEFSKRWTASQLLTHPFL 951
            +G+G  G VYK +H  T ++ A+KV+    D     ++ +E+ +L++ +    I   +G F K  P G    + ++ME+  +G++  L+   K  T  E  +A++  +IL+GLS+LH HK+IHRDIK  N+L+   N +VK+ DFGVS  + R++   N+++GT  +M+PE    D           D+WS          G  P       P  A  +  I     P L     S +F+SFIE CL K  S+R    QL+ HPF+
Sbjct:   31 VGNGTYGQVYKGRHVKTGQLAAIKVMDVTGDE--EEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLL-TENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSLGITAIEMAEGAPPLCD--MHPMRALFL--IPRNPAPRLKSKKWSKKFQSFIESCLVKNHSQRPATEQLMKHPFI 289          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: SLK_MOUSE (STE20-like serine/threonine-protein kinase OS=Mus musculus GN=Slk PE=1 SV=2)

HSP 1 Score: 118.627 bits (296), Expect = 5.235e-26
Identity = 81/260 (31.15%), Postives = 130/260 (50.00%), Query Frame = -2

Query:  181 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDT-LLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSL--PDGASPEFRSFIECCLQKEFSKRWTASQLLTHPFL 951
            LG G  G VYK Q++ T+ + A KV+   ++  +   +  E++IL   D P IV+    F   + ++ IL+E+   G +D  +L      +E ++  +  Q L+ L+YLH +KIIHRD+K  N+L   +   +K+ADFGVS    R++   +S++GT  +M+PE    +           D+WS                 P    +   ++  I   +PP+L  P   S  F+ F+  CL+K    RWT SQLL HPF+
Sbjct:   40 LGDGAFGKVYKAQNKETNVLAAAKVIDTKSEEELEDYMV-EIDILASCDHPNIVKLLDAFYYEN-NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLEALNYLHDNKIIHRDLKAGNILFTLDG-DIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE----IEPPHHELNPMRVLLKIAKSEPPTLAQPSKWSSNFKDFLRKCLEKNVDARWTTSQLLQHPFV 292          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: MP2K2_XENLA (Dual specificity mitogen-activated protein kinase kinase 2 (Fragment) OS=Xenopus laevis GN=map2k2 PE=1 SV=1)

HSP 1 Score: 118.627 bits (296), Expect = 5.235e-26
Identity = 88/271 (32.47%), Postives = 135/271 (49.82%), Query Frame = -2

Query:  181 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEI-LRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTF-----SEPKLAHMASQILKGLSYLHGH-KIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATL---MCAICFGDPPSLPDGA----SPEFRSFIECCLQKEFSKRWTASQLLTHPFL 951
            +G G  G+V K+ H  + +I A+K +    D   ++Q+  ++++ +R +D P+IVQ +G   +  GD  I ME M + + D       +F      E  L  +    +K L++L  + KIIHRDIKPSN+L++ N   +K+ DFG+S  +  S+ A     G   YM+PER DP            D+WS          G FP+      P W ++   +  +  GDPP L +      SP F SF+  CL K+ SKR    +LL HPF+
Sbjct:  155 IGRGAYGSVNKMSHTPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFR-EGDCWICMELMAT-SFDKFYKYVYSFLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDTNG-NIKLCDFGISGQLVDSI-AKTRDAGCRPYMAPERIDPSASRQGYDVRS-DVWSLGITLYELATGRFPY------PKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFTSFVNQCLTKDESKRPKYKELLKHPFI 414          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: STK10_MOUSE (Serine/threonine-protein kinase 10 OS=Mus musculus GN=Stk10 PE=1 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 6.838e-26
Identity = 81/262 (30.92%), Postives = 134/262 (51.15%), Query Frame = -2

Query:  175 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTL-LNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSL--PDGASPEFRSFIECCLQKEFSKRWTASQLLTHPFLCK 951
            LG G  G VYK +++ T  + A KV+   ++  +   +  E+EIL   D P+IV+  G +    G + I++E+   G +D + L  +   +EP++  +  Q+L+ L++LHG +IIHRD+K  N+L+      +++ADFGVS    ++L   +S++GT  +M+PE    +           DIWS                 P    +   ++  I   DPP+L  P   S EFR F++  L K    R +A+QLL HPF+ +
Sbjct:   42 LGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIV-EIEILATCDHPYIVKLLGAYYY-DGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEG-DIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMA----QIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLQHPFVSR 296          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: SLK_HUMAN (STE20-like serine/threonine-protein kinase OS=Homo sapiens GN=SLK PE=1 SV=1)

HSP 1 Score: 117.472 bits (293), Expect = 1.166e-25
Identity = 81/260 (31.15%), Postives = 129/260 (49.62%), Query Frame = -2

Query:  181 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDT-LLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSL--PDGASPEFRSFIECCLQKEFSKRWTASQLLTHPFL 951
            LG G  G VYK Q++ T  + A KV+   ++  +   +  E++IL   D P IV+    F   + ++ IL+E+   G +D  +L      +E ++  +  Q L  L+YLH +KIIHRD+K  N+L   +   +K+ADFGVS    R++   +S++GT  +M+PE    +           D+WS                 P    +   ++  I   +PP+L  P   S  F+ F++ CL+K    RWT SQLL HPF+
Sbjct:   40 LGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMV-EIDILASCDHPNIVKLLDAFYYEN-NLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDG-DIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAE----IEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFV 292          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: M3K3_ARATH (Mitogen-activated protein kinase kinase kinase 3 OS=Arabidopsis thaliana GN=ANP3 PE=1 SV=1)

HSP 1 Score: 117.472 bits (293), Expect = 1.166e-25
Identity = 76/229 (33.19%), Postives = 121/229 (52.84%), Query Frame = -2

Query:  166 RQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSK--IMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSLPDGASPEFRSFIECCLQKEFSKRWTASQLLTHPFLCKNRR 846
            R++  E+++L+    P IV+  G   + S  + ILME++  G++ +LL K G+F EP +     Q+L GL YLH + I+HRDIK +N+LV+N    +++ADFG SK  +   +++   S  GT  +M+PE                DIWS          G  P+ +  Q   +A ++        P +P+  SPE + F+  CL KE S R +A++LL HPF+   R+
Sbjct:  116 RELEEEVQLLKNLSHPNIVRYLGTVRE-SDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEYLHNNGIMHRDIKGANILVDNKGC-IRLADFGASKKVVELATVNGAKSMKGTPYWMAPE-----VILQTGHSFSADIWSVGCTVIEMATGKPPWSE--QYQQFAAVLHIGRTKAHPPIPEDLSPEAKDFLMKCLHKEPSLRLSATELLQHPFVTGKRQ 335          

BLAST of CX672513 vs. ExPASy Swiss-Prot
Match: SVKA_DICDI (Serine/threonine-protein kinase svkA OS=Dictyostelium discoideum GN=svkA PE=1 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 1.523e-25
Identity = 84/257 (32.68%), Postives = 132/257 (51.36%), Query Frame = -2

Query:  181 LGHGNGGTVYKVQHRCTHKIYALKVVHGDADPTVRRQVFREMEILRRTDSPFIVQCFGIFEKPSGDIAILMEYMDSGTLDTLLNKNGTFSEPKLAHMASQILKGLSYLHGHKIIHRDIKPSNLLVNNNNMQVKIADFGVSKIMCRSLDACNSYVGTCAYMSPERFDPDXXXXXXXXXXGDIWSXXXXXXXXXLGHFPFLQPGQRPDWATLMCAICFGDPPSLPDGASPEFRSFIECCLQKEFSKRWTASQLLTHPFL 951
            +G G+ G V+K  ++ T++  A+K +  +        + +E+ +L + +SPF+ + FG F K S  + I+MEY+  G++  L+ K G F E  +A +  ++LKGL YLH    IHRDIK +N+L++ +   VK+ADFGVS  +   +   N++VGT  +M+PE                DIWS          G  P  +    P  A  +  I    PP+L    S  F+ F   CL K+ ++R TA  LL H F+
Sbjct:   18 IGKGSFGEVFKGINKKTNETIAIKTIDLEDAEDEIEDIQQEINVLSQCESPFVTKYFGSFLKGS-KLWIIMEYLAGGSVLDLM-KPGPFDEGYIAIILRELLKGLEYLHSEGKIHRDIKAANVLLSASG-DVKLADFGVSGQLTDQMTKRNTFVGTPFWMAPE-----VIKQTGYDSKADIWSMGITALEMAKGEPP--RADLHPMRALFL--IPKDPPPTLEGNFSKGFKEFCALCLNKDPNQRPTAKDLLKHKFI 262