CX671670

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: Y7165_DICDI (Probable serine/threonine-protein kinase DDB_G0277165 OS=Dictyostelium discoideum GN=DDB_G0277165 PE=3 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 3.681e-17
Identity = 58/215 (26.98%), Postives = 110/215 (51.16%), Query Frame = 3

Query:  156 LGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAHSMLGTPEFMAPELYDE-DYT-ELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSG 794
            LG G   KV   F ++ G +V    +      + P+M  ++  E+ L+K + + N + ++ V+  E    L  I E    G L +Y  +   +       + +QI+ GL Y H+   C  HRDL   N+ ++G+  ++KI D G+ +IV K    H+  G+P + +PE+    DY  +  D++S G+ +  ++T ++P+ + +N+ ++  KV +G
Sbjct:   15 LGQGTTGKVKLGFHKDTGFKVGIKIINKELLINKPSMRRKIEREIVLMKLIDHPNAMKMYEVY--ETSKYLFLILEYVEGGELFDYLVEKGGLESGEALFFFQQIIIGLEYCHSRNIC--HRDLKPENLLLSGDK-RIKIADFGMGSIVRKDMLLHTSCGSPHYASPEVVSGIDYDGQKADVWSCGVILYALLTGKLPFDD-ENIRRLLNKVKNG 223          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: PLK_DICDI (Probable serine/threonine-protein kinase PLK OS=Dictyostelium discoideum GN=PLK PE=3 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 3.681e-17
Identity = 65/256 (25.39%), Postives = 126/256 (49.22%), Query Frame = 3

Query:   63 MPAVNSDP--SDKDSEPFI--ETDPTG-----RYGRYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAHSMLGTPEFMAPELYDED--YTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQ 797
            MP   S P  S++  EP +  ET  +G     +  R  E LG G   K Y   + E     A   +   T     A   +L SE+++  +L+++NI+   + + +E+   +  + E+C    + +  KK +++     K +  Q++  + YLH +   +IHRDL   N+F++    ++K+GD G++  V       ++ GTP ++APE+ D    ++  VD++S G+ +  ++  + P+ E  +V   Y+++   Q
Sbjct:  129 MPPPQSLPNKSNEPQEPIVVYETIRSGDSKRLKEYRQGEFLGKGGFAKCYLMTEVETNRIYAAKIIPKSTLQKTRAR-SKLKSEIKIHSSLSHENIVKFEHCFENEEN--VYILLELCNQKTVMDIHKKRKYLMEYETKYYVYQVIMAVQYLHNNN--IIHRDLKLGNLFIDNM--RIKLGDFGLSTKVEHGERKKTICGTPNYIAPEILDNSNGHSYEVDVWSIGIILYTLLIGKPPF-ETSDVKHTYQRIKQNQ 376          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: PLK3_RAT (Serine/threonine-protein kinase PLK3 (Fragment) OS=Rattus norvegicus GN=Plk3 PE=2 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 3.681e-17
Identity = 65/240 (27.08%), Postives = 115/240 (47.92%), Query Frame = 3

Query:   66 PAVNSDPSDKDSEPFIETDPTGRYGRYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAA-IVGKSHSAHSMLGTPEFMAPE-LYDEDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYK 779
            P V + P   D+   I    +GR      LLG G   + Y A D E  I  A   +  ++    P   E++ +E+ L + L +++I+   + + D D   +    E+C+  +L    K    +    ++ + +QIL GL YL  H+  ++HRDL   N F+  N  ++K+GD G+AA +        ++ GTP ++APE L  + +    D++S G CV+  +    P  E  ++ + Y+
Sbjct:    7 PEVLAGPQTPDASRLITDPRSGRTYIKGRLLGKGGFARCYEATDTETSIAYAVKVIP-QSRVAKPHQREKIINEIELHRDLQHRHIVRFSHHFEDADN--IYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYL--HQRGILHRDLKLGNFFITDNM-ELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLG-CVMYTLLCGSPPFETADLKETYR 239          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: KRAF1_CAEEL (Raf homolog serine/threonine-protein kinase OS=Caenorhabditis elegans GN=lin-45 PE=1 SV=2)

HSP 1 Score: 88.9669 bits (219), Expect = 3.681e-17
Identity = 74/237 (31.22%), Postives = 113/237 (47.68%), Query Frame = 3

Query:  156 LGSGAVKKVYRA-FDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVK---------ALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAI-----VGKSHSAHSMLGTPEFMAPELY----DEDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQ-RPD 806
            +GSG+   VYR  F     I+      KL      P+ +    +EV +LK   + N++ L   W  E    +  IT+ C   +L      +RH+ V+         A+    KQ+  G+NYLH+    +IHRDL  +N+F+  +   VKIGD G+A +     V          G+  +MAPE+     D  YT   D+YSFG+C+ E+++  +PYS  +N  +I   V  G  RPD
Sbjct:  487 VGSGSFGTVYRGEFFGTVAIK------KLNVVDPTPSQMAAFKNEVAVLKKTRHLNVL-LFMGWVREPE--IAIITQWCEGSSL------YRHIHVQEPRVEFEMGAIIDILKQVSLGMNYLHSKN--IIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGICMYEILSSHLPYSNINNRDQILFMVGRGYLRPD 706          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: M3K10_MOUSE (Mitogen-activated protein kinase kinase kinase 10 OS=Mus musculus GN=Map3k10 PE=2 SV=2)

HSP 1 Score: 88.5817 bits (218), Expect = 4.807e-17
Identity = 80/252 (31.75%), Postives = 117/252 (46.43%), Query Frame = 3

Query:   57 FMMPAVNSDPSD---KDSEPFIETDPTGRYGRYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPC-VIHRDLNCSNVFV-----NGNTGQ--VKIGDLGVAAIVGKSHSAHSMLGTPEFMAPELYDED-YTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIY 776
            ++ PA  + PSD       PF E        +  E++G G   KVYRA  + E  EVA    +L    D     E++  E RL   L + NII+L           L  + E    G L       R V    L  W+ Q+ +G+NYLH   P  +IHRDL   N+ +     N N     +KI D G+A    K+ +  S  GT  +MAPE+     +++  D++SFG+ + E++T E+PY E D +A  Y
Sbjct:   75 YVAPAAPAAPSDLQLPQEIPFHEL-------QLEEIIGVGGFGKVYRAVWRGE--EVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSPPN--LCLVMEYARGGALSRVLAGRR-VPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKT-TKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAY 313          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: BCK1_YEAST (Serine/threonine-protein kinase BCK1/SLK1/SSP31 OS=Saccharomyces cerevisiae GN=BCK1 PE=1 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 4.807e-17
Identity = 68/226 (30.09%), Postives = 112/226 (49.56%), Query Frame = 3

Query:  150 ELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDP----AMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGK--SHSAHSMLGTPEFMAPELYD--EDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQRP 803
            E++G G+   VY   +   G  +A  QV++  +        + +E L SEV  LK L + NI+   Y+  +   N  +   E    G++    + +       +K  + Q+LKGL YLH+    ++HRD+   N+ ++ + G  KI D G++       S+S  +M GT  +MAPE+ D  + Y+  VDI+S G  VLEM   + P+S  + VA ++K   S   P
Sbjct: 1179 EMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQ--YLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKG--ILHRDMKADNLLLDQD-GICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAP 1399          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: KRAF1_CAEBR (Raf homolog serine/threonine-protein kinase OS=Caenorhabditis briggsae GN=lin-45 PE=3 SV=2)

HSP 1 Score: 88.1965 bits (217), Expect = 6.278e-17
Identity = 75/240 (31.25%), Postives = 114/240 (47.50%), Query Frame = 3

Query:  156 LGSGAVKKVYRA-FDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVS-------VKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAI-----VGKSHSAHSMLGTPEFMAPELY----DEDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQRPDALNKIK 824
            +GSG+   VYR  F     I+      KL      P+ +    +EV +LK   + N++ L   W  E    +  IT+ C   +L  YR  H HV        + A+    KQ+  G+NYLH+    +IHRDL  +N+F+  +   VKIGD G+A +     V          G+  +MAPE+     D  YT   D+YSFG+C+ E+++  +PYS  +N  +I   V  G      +KI+
Sbjct:  485 VGSGSFGTVYRGEFFGTVAIK------KLNVVDPTPSQMAAFKNEVAVLKKTRHLNVL-LFMGWVREPE--IAIITQWCEGSSL--YR--HIHVQEPRVEFEMSAVIDILKQVSLGMNYLHSKN--IIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGVCMYEILSSHLPYSNINNRDQILFMVGRGYLKPDRSKIR 709          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: PLK4_XENTR (Serine/threonine-protein kinase PLK4 OS=Xenopus tropicalis GN=plk4 PE=2 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 8.199e-17
Identity = 66/227 (29.07%), Postives = 117/227 (51.54%), Query Frame = 3

Query:  153 LLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRK-KHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAH-SMLGTPEFMAPELYDEDYTEL-VDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKV--SSGQRPDALNK 818
            LLG G+   VYRA     GI+VA   +  +       M++R+ +EV +   L + +I+ L+  +  ED N +  I E+C +G +  + K + +  S    + +  QI+ G+ YLH+H   ++HRDL  SN+ ++ +   +KI D G+A  +   +  H +M GTP ++APE+       L  D++S G C+L    +  P  + D V     K+  +  + PD +++
Sbjct:   17 LLGKGSFACVYRAQSINTGIDVAIKMIDKKAM-QKVGMVQRVRNEVEIHCQLKHPSILELYNYF--EDSNYVYLILEMCHNGEMNRFLKNRKKPFSEDEARHFMHQIVTGMLYLHSHG--ILHRDLTLSNLLLSSDM-NIKIADFGLATQLKMPNEKHFTMCGTPNYIAPEIATRSAHGLESDVWSLG-CMLYTFLVGRPPFDTDTVKNTLNKIVLADYEMPDFVSR 236          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: PLK4_XENLA (Serine/threonine-protein kinase PLK4 OS=Xenopus laevis GN=plk4 PE=2 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 8.199e-17
Identity = 66/227 (29.07%), Postives = 117/227 (51.54%), Query Frame = 3

Query:  153 LLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRK-KHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAH-SMLGTPEFMAPELYDEDYTEL-VDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKV--SSGQRPDALNK 818
            LLG G+   VYRA     GI+VA   +  +       M++R+ +EV +   L + +I+ L+  +  ED N +  I E+C +G +  Y K + +  +    + +  QI+ G+ YLH+H   ++HRDL  SN+ ++ +   +KI D G+A  +   +  H +M GTP ++APE+       L  D++S G C+L    +  P  + D V     K+  +  + PD +++
Sbjct:   17 LLGKGSFACVYRAQSINTGIDVAIKMIDKKAM-QKVGMVQRVRNEVEIHCQLKHPSILELYNYF--EDSNYVYLILEMCHNGEVNRYLKNRKKPFAEDEARHFMHQIVTGMLYLHSHG--ILHRDLTLSNLLLSSDM-NIKIADFGLATQLKMPNEKHFTMCGTPNYIAPEIATRSAHGLESDVWSLG-CMLYTFLVGRPPFDTDTVKNTLNKIVLADYEMPDFVSR 236          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: PLK1_MOUSE (Serine/threonine-protein kinase PLK1 OS=Mus musculus GN=Plk1 PE=2 SV=2)

HSP 1 Score: 87.4261 bits (215), Expect = 1.071e-16
Identity = 64/235 (27.23%), Postives = 121/235 (51.49%), Query Frame = 3

Query:  105 PFIETDPTGR--YGRYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVG-KSHSAHSMLGTPEFMAPE-LYDEDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQ 797
            P +  DP  R  Y R    LG G   K +   D +   EV   ++  ++    P   E++  E+ + ++LA+++++  H  + D D   +  + E+C   +L E  K+ + ++    + + +QI+ G  YLH ++  VIHRDL   N+F+N +  +VKIGD G+A  V  +     ++ GTP ++APE L  + ++  VD++S G C++  + +  P  E   + + Y ++   +
Sbjct:   41 PEVLVDPRSRRQYVR-GRFLGKGGFAKCFEISDADTK-EVFAGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQHVVGFHDFFEDSD--FVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNQ--VIHRDLKLGNLFLNEDL-EVKIGDFGLATKVEYEGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIG-CIMYTLLVGKPPFETSCLKETYLRIKKNE 267