DT214588

BLAST of DT214588 vs. ExPASy Swiss-Prot
Match: CP17A_FELCA (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Felis catus GN=CYP17A1 PE=2 SV=1)

HSP 1 Score: 102.449 bits (254), Expect = 3.412e-21
Identity = 63/190 (33.16%), Postives = 98/190 (51.58%), Query Frame = -1

Query:  165 DLIAGATETSTLMLEWAFAELVKNPEILDKAREELDRVIGKERWFEEKDIVNLPFIEAIIKETMRLHG-APMLMPRMAREDCKVAGYDILKGTQVLVNTWTIERDPALWENPNEFCPERFLGKS-IDVKGNDFELLPFGAGRRMCPGYSNGLKVIQSSLANLLHGFTWKLP--GNMSNKELNMEEVFKLA 722
            D+     ET+T ++ W  A L+ +P++  K +EE+D+ IG  R     D   L  +EA I+E +R+   AP L+P  A  D  +  + + KGT V++N W +  +   W  P++F PERFL  +   +       LPFGAG R C G S   + +   +A LL  F  ++P  G + + E N   VF +A
Sbjct:  298 DIFGAGVETTTSVVRWTVAFLLHHPQLYKKLQEEIDQNIGFSRTPTMSDRNQLILLEATIREVLRIRPVAPTLIPHKAIMDSSIGEFAVDKGTNVIINLWALHHNEKEWYRPDQFMPERFLDPTRSQLISPSLSYLPFGAGPRSCLGESLARQEVFLFMAWLLQRFDLEVPDDGQLPHLEGNPTVVFLIA 487          

BLAST of DT214588 vs. ExPASy Swiss-Prot
Match: CP1A2_HUMAN (Cytochrome P450 1A2 OS=Homo sapiens GN=CYP1A2 PE=1 SV=3)

HSP 1 Score: 101.293 bits (251), Expect = 7.601e-21
Identity = 66/174 (37.93%), Postives = 90/174 (51.72%), Query Frame = -1

Query:  216 DLIAGATETSTLMLEWAFAELVKNPEILDKAREELDRVIGKERWFEEKDIVNLPFIEAIIKETMRLHGA--PMLMPRMAREDCKVAGYDILKGTQVLVNTWTIERDPALWENPNEFCPERFL---GKSIDVKGNDFELLPFGAGRRMCPGYSNGLKVIQSSLANLLHGFTWKLP 722
            D+     +T T  + W+   LV  PEI  K ++ELD VIG+ER     D   LP++EA I ET R H +  P  +P     D  + G+ I K   V VN W +  DP LWE+P+EF PERFL   G +I+ K    +++ FG G+R C G       I   LA LL    + +P
Sbjct:  313 DIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFR-HSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAIN-KPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVP 484          

BLAST of DT214588 vs. ExPASy Swiss-Prot
Match: CP2A3_RAT (Cytochrome P450 2A3 OS=Rattus norvegicus GN=Cyp2a3 PE=2 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 9.927e-21
Identity = 59/172 (34.30%), Postives = 91/172 (52.91%), Query Frame = -1

Query:  216 TLDLIAGATETSTLMLEWAFAELVKNPEILDKAREELDRVIGKERWFEEKDIVNLPFIEAIIKETMRLHG-APMLMPRMAREDCKVAGYDILKGTQVLVNTWTIERDPALWENPNEFCPERFLGKSIDVKGNDFELLPFGAGRRMCPGYSNGLKVIQSSLANLLHGFTWKLP 728
            TL+L    TET +  L + F  L+K+P+I  K  EE+DRVIG+ R  + +D + +P+ EA+I E  R     PM + R   +D K   + + KGT+V     ++ +DP  + NPN+F P+ FL      K +D   +PF  G+R C G       +   L N++  F +K P
Sbjct:  295 TLNLFFAGTETVSTTLRYGFLLLMKHPDIEAKVHEEIDRVIGRNRQAKYEDRMKMPYTEAVIHEIQRFADMIPMGLARRVTKDTKFREFLLPKGTEVFPMLGSVLKDPKFFSNPNDFNPKHFLDDKGQFKKSD-AFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFCFKSP 465          

BLAST of DT214588 vs. ExPASy Swiss-Prot
Match: CP1A2_CAVPO (Cytochrome P450 1A2 OS=Cavia porcellus GN=CYP1A2 PE=2 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 9.927e-21
Identity = 68/217 (31.34%), Postives = 104/217 (47.93%), Query Frame = -1

Query:  117 LDRHSVKGFTLDLIAGATETSTLMLEWAFAELVKNPEILDKAREELDRVIGKERWFEEKDIVNLPFIEAIIKETMRLHG-APMLMPRMAREDCKVAGYDILKGTQVLVNTWTIERDPALWENPNEFCPERFL---GKSIDVKGNDFELLPFGAGRRMCPGYSNGLKVIQSSLANLLHGFTWKLPGNMSNKELNMEEVFKLANQKKIPLEVVAQPRLA 755
            + R  +     D+     +T T  + W+   LV  PEI  K  +ELD VIG++R     D   LP++EA I E  R     P  +P     D  + G+ I K   V +N W +  DP  WE+P EF PERFL     ++D   +D ++L FG G+R C G + G   +   LA LL    + +P  +   ++++  V+ L  +      V A+PR +
Sbjct:  302 IPRKKIVNLVNDIFGAGFDTVTTAISWSLLYLVTKPEIQKKIHKELDAVIGRDRKPRLADRPQLPYMEAFILEVFRYSSFLPFTIPHCTTRDTILNGFYIPKDRCVFINQWQVNHDPKQWEDPFEFRPERFLLANNTAVDKTLSD-KILLFGLGKRRCIGETLGRWEVFLFLAILLQQLEFSVPPGV---KVDLTPVYGLTMKPPHCQHVQARPRFS 514          

BLAST of DT214588 vs. ExPASy Swiss-Prot
Match: CP17A_RANDY (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Rana dybowskii GN=CYP17A1 PE=2 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 9.927e-21
Identity = 67/202 (33.17%), Postives = 109/202 (53.96%), Query Frame = -1

Query:  123 DLIAGATETSTLMLEWAFAELVKNPEILDKAREELDRVIGKERWFEEKDIVNLPFIEAIIKETMRLHG-APMLMPRMAREDCKVAGYDILKGTQVLVNTWTIERDPALWENPNEFCPERFLGKSID-VKGNDFELLPFGAGRRMCPGYSNGLKVIQSSLANLLHGFTWKLPGNMSNKELNMEEVFKLANQKKIPLEVVAQPR 722
            D+     ET++ +L+WA A L+  PE+  K +EELD  +G  R+    D   L + EA I E +R+   +P+L+P +A ++  +  Y I K  +V++N W++  D   W NP+ F P+RFL ++ + V       LPFGAG R+C G +     +   L+ +L  FT ++P      +L  E  F +  Q K P +V+A+ R
Sbjct:  311 DIFGAGVETTSTVLKWAVAYLLHYPEVQKKIQEELDVKVGFGRYPLLSDRKILHYTEAAISEVLRIRPVSPLLIPHVALKESSIGEYTIPKEARVVINLWSLHHDEKEWVNPHLFSPDRFLDENGNRVYSPSPSFLPFGAGIRVCLGEALAKMEVFLFLSWILQRFTLEVPEGDPLPDL--EGKFGVVIQVK-PFKVIAKLR 509          

BLAST of DT214588 vs. ExPASy Swiss-Prot
Match: CP3AR_ONCMY (Cytochrome P450 3A27 OS=Oncorhynchus mykiss GN=cyp3a27 PE=2 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 1.296e-20
Identity = 60/214 (28.04%), Postives = 105/214 (49.07%), Query Frame = -1

Query:  114 LDRHSVKGFTLDLIAGATETSTLMLEWAFAELVKNPEILDKAREELDRVIGKERWFEEKDIVNLPFIEAIIKETMRLHGAPMLMPRMAREDCKVAGYDILKGTQVLVNTWTIERDPALWENPNEFCPERFLGKSIDVKGNDFELLPFGAGRRMCPGYSNGLKVIQSSLANLLHGFTWKLPGNMSNKELNMEEVFKLANQKKIPLEVVAQPRLAP 755
            L  H +    +  I    ETS+  + +    L  N  ++ K +EE+D V   +   + + ++ + +++ ++ E++RL+     + R+A++  ++ G  I K   VLV TWT+ RDP +W +P EF PERF  K      + +  +PFGAG R C G    L +I+ ++  +L  FT                 F + ++ +IPLE+  Q  L P
Sbjct:  295 LTDHEILSQAMIFIFAGYETSSSTMSFLAYNLATNHHVMTKLQEEIDTVFPNKAPIQYEALMQMDYLDCVLNESLRLYPIAPRLERVAKKTVEINGIVIPKDCIVLVPTWTLHRDPEIWSDPEEFKPERF-SKENKESIDPYTYMPFGAGPRNCIGMRFALIMIKLAMVEILQSFT-----------------FSVCDETEIPLEMDNQGLLMP 490          

BLAST of DT214588 vs. ExPASy Swiss-Prot
Match: CP21A_LYNLY (Steroid 21-hydroxylase OS=Lynx lynx GN=CYP21 PE=3 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 1.296e-20
Identity = 73/206 (35.44%), Postives = 96/206 (46.60%), Query Frame = -1

Query:  123 LDLIAGATETSTLMLEWAFAELVKNPEILDKAREELDRVIGKERWFEE---KDIVNLPFIEAIIKETMRLHGA-PMLMPRMAREDCKVAGYDILKGTQVLVNTWTIERDPALWENPNEFCPERFLGKSIDVKGNDFELLPFGAGRRMCPGYSNGLKVIQSSLANLLHGFTWKLP-GNMSNKELNMEEVFKLANQKKIPLEVVAQPR 725
            +DL  G TET+   L WA A L+ +PEI  + +EELD  +G          KD   LP + A I E +RL    P+ +P        + GYDI +GT V+ N      D  +WE P+EF P+RFL     V G    +L FG G R+C G       +   LA LLH FT   P G + +          L  Q   P +V  QPR
Sbjct:  284 VDLFIGGTETTATTLSWAVAFLLHHPEIQQRLQEELDCELGPGASGSRVPLKDPSRLPLLTATIAEVLRLRPVVPLALPHRTTRHSSILGYDIPEGTVVIPNLQGAHLDDTVWEQPHEFRPDRFL-----VPGASPRVLAFGCGARVCLGEPLARLELFVVLARLLHAFTLLPPTGPLPSLRPRSHCGINLTMQ---PFQVQLQPR 481          

BLAST of DT214588 vs. ExPASy Swiss-Prot
Match: CP21A_FELCA (Steroid 21-hydroxylase OS=Felis catus GN=CYP21 PE=3 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 1.693e-20
Identity = 64/170 (37.65%), Postives = 84/170 (49.41%), Query Frame = -1

Query:  228 LDLIAGATETSTLMLEWAFAELVKNPEILDKAREELDRVIGKERWFEE---KDIVNLPFIEAIIKETMRLHGA-PMLMPRMAREDCKVAGYDILKGTQVLVNTWTIERDPALWENPNEFCPERFLGKSIDVKGNDFELLPFGAGRRMCPGYSNGLKVIQSSLANLLHGFT 725
            +DL  G TET+   L WA A L+ +PEI  + +EELD  +G          KD   LP + A I E +RL    P+ +P        + GYDI +GT V+ N      D  +WE P+EF P+RFL     V G    +L FG G R+C G       +   LA LLH FT
Sbjct:  284 VDLFIGGTETTATTLSWAVAFLLHHPEIQQRLQEELDCELGPGASGSRVPLKDPSRLPLLTATIAEVLRLRPVVPLALPHRTTRHSSILGYDIPEGTVVIPNLQGAHLDDTVWEQPHEFRPDRFL-----VPGASPRVLAFGCGARVCLGEPLARLELFVVLARLLHAFT 448          

BLAST of DT214588 vs. ExPASy Swiss-Prot
Match: CP17A_MOUSE (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Mus musculus GN=Cyp17a1 PE=2 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 1.693e-20
Identity = 59/170 (34.71%), Postives = 88/170 (51.76%), Query Frame = -1

Query:  231 DLIAGATETSTLMLEWAFAELVKNPEILDKAREELDRVIGKERWFEEKDIVNLPFIEAIIKETMRLHG-APMLMPRMAREDCKVAGYDILKGTQVLVNTWTIERDPALWENPNEFCPERFLGKSIDVKGNDF-----ELLPFGAGRRMCPGYSNGLKVIQSSLANLLHGF 722
            D+     ET++ +L W  A LV NPE+  K ++E+D+ +G  R     D  +L  +EA I+E +R+   AP+L+P  A  D  +  + I K T V++N W +  D   W+ P+ F PERFL    D  G+         LPFGAG R C G +   + +   +A LL  F
Sbjct:  297 DIFGAGIETTSSVLNWILAFLVHNPEVKRKIQKEIDQYVGFSRTPSFNDRTHLLMLEATIREVLRIRPVAPLLIPHKANIDSSIGEFAIPKDTHVIINLWALHHDKNEWDQPDRFMPERFL----DPTGSHLITPTPSYLPFGAGPRSCIGEALARQELFIFMALLLQRF 462          

BLAST of DT214588 vs. ExPASy Swiss-Prot
Match: CP4V3_RAT (Cytochrome P450 4V3 OS=Rattus norvegicus GN=Cyp4v3 PE=2 SV=1)

HSP 1 Score: 99.7525 bits (247), Expect = 2.211e-20
Identity = 58/173 (33.53%), Postives = 95/173 (54.91%), Query Frame = -1

Query:  186 ETSTLMLEWAFAELVKNPEILDKAREELDRVIGKE-RWFEEKDIVNLPFIEAIIKETMRLHGAPMLMPRMAREDCKVAGYDILKGTQVLVNTWTIERDPALWENPNEFCPERFLGKSIDVKGNDFELLPFGAGRRMCPGYSNGLKVIQSSLANLLHGFTWKLPGNMSNKELNM 701
            +T+   + W+   L  NPE+  K  +ELD V G+  R    +D+  L +++ +IKET+R+  +  L  R   EDC+VAGY I KGT+ ++  + + RDP  + +P EF PERF  ++   + + +  +PF AG R C G    +   ++ LA +L  F W +  N   +EL +
Sbjct:  332 DTTAAAINWSLYLLGSNPEVQRKVDKELDDVFGRSHRPVTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVAGYKISKGTEAVIIPYALHRDPRYFPDPEEFQPERFFPENSQGR-HPYAYVPFSAGPRNCIGQKFAVMEEKTILACILREF-W-IESNQKREELGL 501