CX289070

BLAST of CX289070 vs. ExPASy Swiss-Prot
Match: AKCL2_PIG (1,5-anhydro-D-fructose reductase OS=Sus scrofa GN=AKR1E2 PE=1 SV=2)

HSP 1 Score: 98.2117 bits (243), Expect = 2.243e-20
Identity = 60/139 (43.17%), Postives = 80/139 (57.55%), Query Frame = 1

Query:  100 KMPVIGLGSAVDNIDERAMKSAVLEAIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVRALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVPL-----DYNGVWEA 501
            K+PV+GLG+      E  +  AV  AI  GYRHFD A LY  E  +G  I   +  G+V  RE+LFI +KLWC+   + LV  A  +SLK L+++Y+DLYLIHWPM  KP E    D+P +    +     D+   WEA
Sbjct:    3 KIPVLGLGTWQAAPGE--VTEAVKVAIDTGYRHFDCAYLYHNENEVGVGIQAKIDEGVVR-REDLFIVSKLWCTCHKKSLVKSACTRSLKALKLQYLDLYLIHWPMGFKPGEV---DLPVDRSGMIVASNTDFLDTWEA 135          

BLAST of CX289070 vs. ExPASy Swiss-Prot
Match: DHB5_MOUSE (Estradiol 17 beta-dehydrogenase 5 OS=Mus musculus GN=Akr1c6 PE=1 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 3.826e-20
Identity = 56/139 (40.29%), Postives = 85/139 (61.15%), Query Frame = 1

Query:  103 MPVIGLGS-AVDNIDERAMKSAVLEAIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVRALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVPLDYNGV-----WEA 501
            +P++G G+ A   + +     A   AI  G+RH D+AS+Y  E+ +G AI   +  G V  RE++F T+K+WC+    +LV   L++SLK LQ++YVDLYLIH+PM+ KP E   N +P+++   L Y+ V     WEA
Sbjct:   16 IPILGFGTYAPQEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIADGTV-KREDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMKPGE---NYLPKDENGKLIYDAVDICDTWEA 150          

BLAST of CX289070 vs. ExPASy Swiss-Prot
Match: ALDR_HUMAN (Aldose reductase OS=Homo sapiens GN=AKR1B1 PE=1 SV=3)

HSP 1 Score: 97.4413 bits (241), Expect = 3.826e-20
Identity = 55/129 (42.64%), Postives = 78/129 (60.47%), Query Frame = 1

Query:  100 KMPVIGLGSAVDNIDERAMKSAVLEAIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVRALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVPLDYN 486
            KMP++GLG+      +  +  AV  AI +GYRH D A +Y  E  +G AI E L+  +V  REELFI +KLWC+   + LV  A +K+L  L+++Y+DLYLIHWP   KP ++        ++VP D N
Sbjct:   12 KMPILGLGTWKSPPGQ--VTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVV-KREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTN 137          

BLAST of CX289070 vs. ExPASy Swiss-Prot
Match: GRE3_YEAST (NADPH-dependent aldose reductase GRE3 OS=Saccharomyces cerevisiae GN=GRE3 PE=1 SV=1)

HSP 1 Score: 97.0561 bits (240), Expect = 4.997e-20
Identity = 51/109 (46.79%), Postives = 75/109 (68.81%), Query Frame = 1

Query:  100 KMPVIGLGSAVDNIDERAMKSAVLEAIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVRALKKSLKTLQIEYVDLYLIHWPMSAK 426
            KMP++GLG     ID++   + + EAIKLGYR FD A  YG E+ +GE I +A+  GLV SR+++F+ +KLW +  H D V  ALKK+L  + ++Y+DLY IH+P++ K
Sbjct:   12 KMPLVGLGCW--KIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLV-SRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFK 117          

BLAST of CX289070 vs. ExPASy Swiss-Prot
Match: AK1C4_MACFU (Aldo-keto reductase family 1 member C4 OS=Macaca fuscata fuscata GN=AKR1C4 PE=1 SV=1)

HSP 1 Score: 97.0561 bits (240), Expect = 4.997e-20
Identity = 57/139 (41.01%), Postives = 80/139 (57.55%), Query Frame = 1

Query:  103 MPVIGLGS-AVDNIDERAMKSAVLEAIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVRALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVPLDYNGVWEA 501
            MPV+G GS A   +    +      AI+ G+RH D+A LY  E  +G AI   +  G V  RE++F T+KLWC+     LV  AL+ SLK LQ++YVDLYLIH+PM+ KP E     +P+++        +D   +WEA
Sbjct:   16 MPVLGFGSYAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSV-KREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPGE---TPLPKDENGKVMFDTVDLCAIWEA 150          

BLAST of CX289070 vs. ExPASy Swiss-Prot
Match: ALDR_MOUSE (Aldose reductase OS=Mus musculus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 96.6709 bits (239), Expect = 6.526e-20
Identity = 55/130 (42.31%), Postives = 76/130 (58.46%), Query Frame = 1

Query:  100 KMPVIGLGSAVDNIDERAMKSAVLEAIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVRALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVPLDYNG 489
            KMP +GLG+      +  +  AV  AI LGYRH D A +Y  E+ +G A+ E LK  +V  R++LFI +KLWC+   + +V  A +K+L  LQ++Y+DLYLIHWP   KP           D  PLD +G
Sbjct:   12 KMPTLGLGTWKSPPGQ--VTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQVV-KRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPG---------PDYFPLDASG 129          

BLAST of CX289070 vs. ExPASy Swiss-Prot
Match: AKC1H_RAT (Aldo-keto reductase family 1 member C18 OS=Rattus norvegicus GN=Akr1c18 PE=1 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 6.526e-20
Identity = 56/150 (37.33%), Postives = 93/150 (62.00%), Query Frame = 1

Query:   73 KLSSASGHRKMPVIGLGSAV--DNIDERAMKSAVLEAIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVRALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVPLDYNGVWEA 501
            K+    GH  +PV+G G+    +N+ +++M+S  + AI +G+RH D + LY  E  +G+AI   ++ G V  RE++F T+KLW +    +LV  +L+ SL+ L ++YVDLYLIH+P+S KP ++L   +P+++     L  +D    WEA
Sbjct:    7 KMELNDGH-SIPVLGFGTYATEENLRKKSMESTKI-AIDVGFRHIDCSHLYQNEEEIGQAIVSKIEDGTV-KREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGDEL---LPQDEHGNLILDTVDLCDTWEA 150          

BLAST of CX289070 vs. ExPASy Swiss-Prot
Match: AK1C4_MACFA (Aldo-keto reductase family 1 member C4 OS=Macaca fascicularis GN=AKR1C4 PE=1 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 1.113e-19
Identity = 56/139 (40.29%), Postives = 80/139 (57.55%), Query Frame = 1

Query:  103 MPVIGLGS-AVDNIDERAMKSAVLEAIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVRALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEED-----LVPLDYNGVWEA 501
            MPV+G G+ A   +    +      AI+ G+RH D+A LY  E  +G AI   +  G V  RE++F T+KLWC+     LV  AL+ SLK LQ++YVDLYLIH+PM+ KP E     +P+++        +D   +WEA
Sbjct:   16 MPVLGFGTYAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSV-KREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALKPGE---TPLPKDENGKVMFDTVDLCAIWEA 150          

BLAST of CX289070 vs. ExPASy Swiss-Prot
Match: A1A1B_DANRE (Alcohol dehydrogenase [NADP+] B OS=Danio rerio GN=akr1a1b PE=2 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 1.113e-19
Identity = 57/142 (40.14%), Postives = 82/142 (57.75%), Query Frame = 1

Query:   97 RKMPVIGLGSAVDNIDERAMKSAVLEAIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVRALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIP---EED----LVPLDYNGVWEA 501
            RKMP++GLG+     +   +K AV+ A++ GYRH D A +Y  E  +GEA  E +       RE++F+T+KLW +  H D V  +L K+LK L++EY+DLYLIHWP + +     R D P   +ED       +DY   W A
Sbjct:   11 RKMPLLGLGTWKS--EPGLVKQAVIWALESGYRHIDCAPIYANEPEIGEAFQETMGPDKGIRREDVFVTSKLWNTKHHPDDVEPSLLKTLKDLKLEYLDLYLIHWPYAFQ-----RGDTPFPRKEDGTLLYDDIDYKLTWAA 145          

BLAST of CX289070 vs. ExPASy Swiss-Prot
Match: ALDR_BOVIN (Aldose reductase OS=Bos taurus GN=AKR1B1 PE=1 SV=1)

HSP 1 Score: 95.5153 bits (236), Expect = 1.454e-19
Identity = 55/130 (42.31%), Postives = 77/130 (59.23%), Query Frame = 1

Query:  100 KMPVIGLGSAVDNIDERAMKSAVLEAIKLGYRHFDTASLYGTERALGEAIAEALKLGLVASREELFITTKLWCSDAHRDLVVRALKKSLKTLQIEYVDLYLIHWPMSAKPSEKLRNDIPEEDLVPLDYNG 489
            KMP++GLG+      +  +  AV  AI LGYRH D A +Y  E  +G A+   L+  +V  RE+LFI +KLWC+   +DLV  A +K+L  L+++Y+DLYLIHWP   KP          +D  PLD +G
Sbjct:   11 KMPILGLGTWKSPPGK--VTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQAKLQEQVV-KREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPG---------KDFFPLDEDG 128