CX294559

BLAST of CX294559 vs. ExPASy Swiss-Prot
Match: ALDR_RAT (Aldose reductase OS=Rattus norvegicus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 190.66 bits (483), Expect = 5.059e-48
Identity = 100/196 (51.02%), Postives = 127/196 (64.80%), Query Frame = 2

Query:   44 HFVLNTGAKIPSVGLGTWQSDPGVVGNAVAAAIKAGYRHIDCAQIYGNEKEIGLVLKKFFEDAVVKREDLWITSKLWNAYHEPEDVPEALDRTLRDLQIDYLDLYLMHWPVKMKKGSVGFKPENLDKPDIPS------TWKAMEALYDSGKARAIGVSNFSTKKLGDLLEV--ARVPPAVNQVECHPSWQQQKLRE 607
            H  LN G K+P++GLGTW+S PG V  AV  AI  GYRHIDCAQ+Y NEKE+G+ L++  ++ VVKR+DL+I SKLW  +H+   V  A  +TL DLQ+DYLDLYL+HWP   K G   F P +     IPS      TW AME L D G  +AIGVSNF+  ++  +L     +  PAVNQ+ECHP   Q+KL E
Sbjct:    4 HLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYF-PLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIE 198          

BLAST of CX294559 vs. ExPASy Swiss-Prot
Match: ALDR_MOUSE (Aldose reductase OS=Mus musculus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 189.504 bits (480), Expect = 1.127e-47
Identity = 99/196 (50.51%), Postives = 126/196 (64.29%), Query Frame = 2

Query:   44 HFVLNTGAKIPSVGLGTWQSDPGVVGNAVAAAIKAGYRHIDCAQIYGNEKEIGLVLKKFFEDAVVKREDLWITSKLWNAYHEPEDVPEALDRTLRDLQIDYLDLYLMHWPVKMKKGSVGFKPENLDKPDIPS------TWKAMEALYDSGKARAIGVSNFSTKKLGDLLEV--ARVPPAVNQVECHPSWQQQKLRE 607
            H  LN G K+P++GLGTW+S PG V  AV  AI  GYRHIDCAQ+Y NEKE+G+ L++  ++ VVKR+DL+I SKLW  +H+   V  A  +TL DLQ+DYLDLYL+HWP   K G   F P +     IPS      TW AME L D G  + IGVSNF+  ++  +L     +  PAVNQ+ECHP   Q+KL E
Sbjct:    4 HLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYF-PLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIE 198          

BLAST of CX294559 vs. ExPASy Swiss-Prot
Match: ALDR_BOVIN (Aldose reductase OS=Bos taurus GN=AKR1B1 PE=1 SV=1)

HSP 1 Score: 189.504 bits (480), Expect = 1.127e-47
Identity = 101/194 (52.06%), Postives = 126/194 (64.95%), Query Frame = 2

Query:   44 HFVLNTGAKIPSVGLGTWQSDPGVVGNAVAAAIKAGYRHIDCAQIYGNEKEIGLVLKKFFEDAVVKREDLWITSKLWNAYHEPEDVPEALDRTLRDLQIDYLDLYLMHWPVKMKKGSVGFKPENLDKPDIPS------TWKAMEALYDSGKARAIGVSNFSTKKLGDLLEV--ARVPPAVNQVECHPSWQQQKL 601
            + VL TGAK+P +GLGTW+S PG V  AV  AI  GYRHIDCA +Y NE E+GL L+   ++ VVKREDL+I SKLW  YH+ + V  A  +TL DL++DYLDLYL+HWP   K G   F P + D   IPS      TW AME L D G  +AIGVSNF+  ++  +L     +  PAVNQ+ECHP   Q+KL
Sbjct:    3 NIVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQAKLQEQVVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK-DFFPLDEDGNVIPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIECHPYLTQEKL 195          

BLAST of CX294559 vs. ExPASy Swiss-Prot
Match: ALRA_DICDI (Aldose reductase A OS=Dictyostelium discoideum GN=alrA PE=2 SV=1)

HSP 1 Score: 187.963 bits (476), Expect = 3.279e-47
Identity = 95/190 (50.00%), Postives = 128/190 (67.37%), Query Frame = 2

Query:   47 FVLNTGAKIPSVGLGTWQSDPGVVGNAVAAAIKAGYRHIDCAQIYGNEKEIGLVL-KKFFEDAVVKREDLWITSKLWNAYHEPEDVPEALDRTLRDLQIDYLDLYLMHWPVKMKKGSVGFKPENLDKP--DIPSTWKAMEALYDSGKARAIGVSNFSTKKLGDLLEVARVPPAVNQVECHPSWQQQKLRE 607
            F L++G KIP VG GTW+++  +VG AV  A+ AGYRHIDCA +Y NEKE+G    KKF  +A VKRED++ITSKLWN +H+ E V  AL+RTL DL + YLDLYL+HWPV  +  S   +     +    I  TW+ ME L D+G  ++IG+SNF+ + L ++L  AR+ PA NQVE HP   Q +L++
Sbjct:    5 FKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKK 194          

BLAST of CX294559 vs. ExPASy Swiss-Prot
Match: ALDR_PIG (Aldose reductase OS=Sus scrofa GN=AKR1B1 PE=1 SV=2)

HSP 1 Score: 186.422 bits (472), Expect = 9.540e-47
Identity = 100/195 (51.28%), Postives = 123/195 (63.08%), Query Frame = 2

Query:   44 HFVLNTGAKIPSVGLGTWQSDPGVVGNAVAAAIKAGYRHIDCAQIYGNEKEIGLVLKKFFEDAVVKREDLWITSKLWNAYHEPEDVPEALDRTLRDLQIDYLDLYLMHWPVKMKKGSVGFKPEN-----LDKPDIPSTWKAMEALYDSGKARAIGVSNFSTKKLGDLLEV--ARVPPAVNQVECHPSWQQQKLRE 607
            H VL TGAK+P +GLGTW+S PG V  AV  AI  GYRHIDCA +Y NE E+GL L++  +  VVKREDL+I SKLW   HE   V  A   TLRDL++DYLDLYL+HWP   K G   F  +       D+ D   TW+AME L D G  +AIGVSNF+  ++  +L     +  PAVNQ+E HP   Q+KL E
Sbjct:    4 HLVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEKLQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDPFPLDGDGNVVPDESDFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIEVHPYLTQEKLIE 198          

BLAST of CX294559 vs. ExPASy Swiss-Prot
Match: A1A1B_DANRE (Alcohol dehydrogenase [NADP+] B OS=Danio rerio GN=akr1a1b PE=2 SV=1)

HSP 1 Score: 186.422 bits (472), Expect = 9.540e-47
Identity = 92/190 (48.42%), Postives = 128/190 (67.37%), Query Frame = 2

Query:   50 VLNTGAKIPSVGLGTWQSDPGVVGNAVAAAIKAGYRHIDCAQIYGNEKEIGLVLKKFF-EDAVVKREDLWITSKLWNAYHEPEDVPEALDRTLRDLQIDYLDLYLMHWPVKMKKGSVGFKPEN-----LDKPDIPSTWKAMEALYDSGKARAIGVSNFSTKKLGDLLEVARVPPAVNQVECHPSWQQQKL 601
            VL+TG K+P +GLGTW+S+PG+V  AV  A+++GYRHIDCA IY NE EIG   ++    D  ++RED+++TSKLWN  H P+DV  +L +TL+DL+++YLDLYL+HWP   ++G   F  +       D  D   TW AME L   G  RAIG+SNF+++++ D+L VA + P V QVE HP   Q +L
Sbjct:    6 VLSTGRKMPLLGLGTWKSEPGLVKQAVIWALESGYRHIDCAPIYANEPEIGEAFQETMGPDKGIRREDVFVTSKLWNTKHHPDDVEPSLLKTLKDLKLEYLDLYLIHWPYAFQRGDTPFPRKEDGTLLYDDIDYKLTWAAMEKLVGKGLVRAIGLSNFNSRQIDDILSVASIKPTVLQVESHPYLAQVEL 195          

BLAST of CX294559 vs. ExPASy Swiss-Prot
Match: A1A1A_DANRE (Alcohol dehydrogenase [NADP+] A OS=Danio rerio GN=akr1a1a PE=2 SV=2)

HSP 1 Score: 186.422 bits (472), Expect = 9.540e-47
Identity = 92/189 (48.68%), Postives = 126/189 (66.67%), Query Frame = 2

Query:   53 LNTGAKIPSVGLGTWQSDPGVVGNAVAAAIKAGYRHIDCAQIYGNEKEIGLVL-KKFFEDAVVKREDLWITSKLWNAYHEPEDVPEALDRTLRDLQIDYLDLYLMHWPVKMKKGS--VGFKPE---NLDKPDIPSTWKAMEALYDSGKARAIGVSNFSTKKLGDLLEVARVPPAVNQVECHPSWQQQKL 601
            L+TG ++P+VGLGTW+S PG V  AV AA+  GYRHIDCA  Y NE+E+G  L ++      ++R+D+++TSKLWN  H P+DV EA  R+L DL++ YLDLYL+HWP+   +G   +   P+     D      TW AME L D G A+AIG+SNF+ K++ D+L +A+  P VNQVECHP   Q +L
Sbjct:    7 LSTGQRMPTVGLGTWKSAPGQVKQAVLAALDCGYRHIDCAAAYSNEREVGEALTERLGPGKSLRRDDIFVTSKLWNTKHHPDDVEEACRRSLSDLRLSYLDLYLIHWPMAFGRGDELIPRHPDGTIQYDDTHYRDTWAAMEKLVDQGLAKAIGLSNFNAKQIDDILSIAKHKPVVNQVECHPYLVQAEL 195          

BLAST of CX294559 vs. ExPASy Swiss-Prot
Match: AK1A1_CRIGR (Alcohol dehydrogenase [NADP+] (Fragment) OS=Cricetulus griseus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 184.496 bits (467), Expect = 3.625e-46
Identity = 94/181 (51.93%), Postives = 121/181 (66.85%), Query Frame = 2

Query:   80 VGLGTWQSDPGVVGNAVAAAIKAGYRHIDCAQIYGNEKEIGLVLKKFFEDA-VVKREDLWITSKLWNAYHEPEDVPEALDRTLRDLQIDYLDLYLMHWPVKMKKGSVGFKPEN------LDKPDIPSTWKAMEALYDSGKARAIGVSNFSTKKLGDLLEVARVPPAVNQVECHPSWQQQKL 601
            +GLGTW+S+PG V  A+  A+  GYRHIDCA +YGNE EIG  LK+       V RE+L++TSKLWN  H PEDV  AL +TL DLQ++YLDLYLMHWP   ++G   F P+N       D      TWKA+EAL   G  +A+G+SNF+++++ D+L VA V PAV QVECHP   Q +L
Sbjct:    2 IGLGTWKSNPGQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREELFVTSKLWNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAFERGDNPF-PKNDDGTIRYDSTHYKETWKALEALVAKGLVKALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNEL 181          

BLAST of CX294559 vs. ExPASy Swiss-Prot
Match: ALDR_RABIT (Aldose reductase OS=Oryctolagus cuniculus GN=AKR1B1 PE=2 SV=3)

HSP 1 Score: 182.956 bits (463), Expect = 1.055e-45
Identity = 97/194 (50.00%), Postives = 125/194 (64.43%), Query Frame = 2

Query:   44 HFVLNTGAKIPSVGLGTWQSDPGVVGNAVAAAIKAGYRHIDCAQIYGNEKEIGLVLKKFFEDAVVKREDLWITSKLWNAYHEPEDVPEALDRTLRDLQIDYLDLYLMHWPVKMKKGSVGFKPENLDKPDIPS------TWKAMEALYDSGKARAIGVSNFSTKKLGDLLEV--ARVPPAVNQVECHPSWQQQKL 601
            H VL  GAK+P +GLGTW+S PG V  AV  AI  GYRHIDCA +Y NE E+G+ L++  ++ VVKRE+L+I SKLW   H+   V  A  +TL DL++DYLDLYL+HWP   K GS  F P +     IPS      TW+AME L D G  ++IGVSNF+  ++  +L     +  PAVNQ+ECHP   Q+KL
Sbjct:    4 HLVLYNGAKMPILGLGTWKSPPGQVTEAVKTAIDLGYRHIDCAHVYQNENEVGVALQEKLKEQVVKREELFIVSKLWCTSHDKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKHGSEYF-PLDAAGNVIPSDTDFLDTWEAMEGLVDEGLVKSIGVSNFNHLQIERILNKPGLKYKPAVNQIECHPYLTQEKL 196          

BLAST of CX294559 vs. ExPASy Swiss-Prot
Match: ALDR_HUMAN (Aldose reductase OS=Homo sapiens GN=AKR1B1 PE=1 SV=3)

HSP 1 Score: 181.415 bits (459), Expect = 3.069e-45
Identity = 93/191 (48.69%), Postives = 121/191 (63.35%), Query Frame = 2

Query:   50 VLNTGAKIPSVGLGTWQSDPGVVGNAVAAAIKAGYRHIDCAQIYGNEKEIGLVLKKFFEDAVVKREDLWITSKLWNAYHEPEDVPEALDRTLRDLQIDYLDLYLMHWPVKMKKGSVGFKPENL-----DKPDIPSTWKAMEALYDSGKARAIGVSNFSTKKLGDLLEV--ARVPPAVNQVECHPSWQQQKL 601
            +LN GAK+P +GLGTW+S PG V  AV  AI  GYRHIDCA +Y NE E+G+ +++   + VVKRE+L+I SKLW  YHE   V  A  +TL DL++DYLDLYL+HWP   K G   F  +          +I  TW AME L D G  +AIG+SNF+  ++  +L     +  PAVNQ+ECHP   Q+KL
Sbjct:    6 LLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKL 196