CX294560

BLAST of CX294560 vs. ExPASy Swiss-Prot
Match: CP17A_RANDY (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Rana dybowskii GN=CYP17A1 PE=2 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 4.888e-24
Identity = 64/187 (34.22%), Postives = 99/187 (52.94%), Query Frame = 1

Query:   49 DRLVDQRLKHRQEHGCSISTECKDILDTLL-----------NIIQDKSVEIETKHLKHFFADLFIAGNDTTSSTMEWAMAELLHNPXXXXXXXXXXXQTVGKCKPIEESDITRLPYLQAVVKETLRLHPAVPLLLPRKATKDVAIAGFTVPKGAQVFVNVWAIGRDESTWDNPHTFIPERFLGSNAD 576
            D+L+ +++   ++  C  +   KD++D LL           N+ QD  V +   H+     D+F AG +TTS+ ++WA+A LLH P             VG  +    SD   L Y +A + E LR+ P  PLL+P  A K+ +I  +T+PK A+V +N+W++  DE  W NPH F P+RFL  N +
Sbjct:  254 DQLLQKKINEHKDAFCGETV--KDLVDALLKAKLNMENNNSNVSQD--VGLTEDHILMTVGDIFGAGVETTSTVLKWAVAYLLHYPEVQKKIQEELDVKVGFGRYPLLSDRKILHYTEAAISEVLRIRPVSPLLIPHVALKESSIGEYTIPKEARVVINLWSLHHDEKEWVNPHLFSPDRFLDENGN 436          

BLAST of CX294560 vs. ExPASy Swiss-Prot
Match: CP17A_ICTPU (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Ictalurus punctatus GN=cyp17a1 PE=2 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 4.888e-24
Identity = 60/191 (31.41%), Postives = 98/191 (51.31%), Query Frame = 1

Query:   31 KMLEVFDRLVDQRLKHRQEHGCSISTEC-KDILDTLL--------NIIQDKSVEIETKHLKHFFADLFIAGNDTTSSTMEWAMAELLHNPXXXXXXXXXXXQTVGKCKPIEESDITRLPYLQAVVKETLRLHPAVPLLLPRKATKDVAIAGFTVPKGAQVFVNVWAIGRDESTWDNPHTFIPERFLGSNAD 576
            + + + D+L+ ++    +EH    S    +D+ D LL        N    + V +   HL     D+F AG +TT++ ++W++  L+H+P             +G+ +  + +D   LPYL+A ++E LR+ P  PLL+P  A  D  I  +TV KG +V VN+W++  DE  W NP  F PERFL    +
Sbjct:  239 RCVSIRDKLLQKKY---EEHKADFSDNIQRDLFDALLRAKNSSENNNTSTQDVGLTDDHLLMTVGDIFGAGVETTTTVLKWSILYLIHHPQVQRKIQEELDAKIGRDRHPQVNDRGNLPYLEATIREVLRIRPVSPLLIPHVALSDANIGEYTVQKGTRVIVNLWSLHHDEKEWKNPELFNPERFLNEEGN 426          

BLAST of CX294560 vs. ExPASy Swiss-Prot
Match: CP17A_PANTR (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Pan troglodytes GN=CYP17A1 PE=2 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 6.384e-24
Identity = 62/163 (38.04%), Postives = 86/163 (52.76%), Query Frame = 1

Query:  103 STECKDILDTLL---------NIIQDKSVEI-ETKHLKHFFADLFIAGNDTTSSTMEWAMAELLHNPXXXXXXXXXXXQTVGKCKPIEESDITRLPYLQAVVKETLRLHPAVPLLLPRKATKDVAIAGFTVPKGAQVFVNVWAIGRDESTWDNPHTFIPERFL 561
            S    ++LDTL+         N   D+  E+    H+     D+F AG +TT+S ++W +A LLHNP           Q VG  +    SD  RL  L+A ++E LRL P  P+L+P KA  D +I  F V KG QV +N+WA+  +E  W  P  F+PERFL
Sbjct:  256 SDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTQVIINLWALHHNEKEWHQPDQFMPERFL 418          

BLAST of CX294560 vs. ExPASy Swiss-Prot
Match: CP17A_ORYLA (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Oryzias latipes GN=cyp17a1 PE=2 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 6.384e-24
Identity = 62/184 (33.70%), Postives = 97/184 (52.72%), Query Frame = 1

Query:   61 DQRLKHR-QEHGCSISTEC-KDILDTLLNIIQD------------KSVEIETKHLKHFFADLFIAGNDTTSSTMEWAMAELLHNPXXXXXXXXXXXQTVGKCKPIEESDITRLPYLQAVVKETLRLHPAVPLLLPRKATKDVAIAGFTVPKGAQVFVNVWAIGRDESTWDNPHTFIPERFLGSN 570
            DQ L+ + +EH    S    +D+LD LL   +             ++V +   HL     D+F AG +TT++ ++WA+  L+H P           + VG  +P + SD   LP+L+A ++E LR+ P  PLL+P  A  D ++  FTV KG +V +N+W++  DE  W NP  F P RFL ++
Sbjct:  247 DQLLQKKFEEHKSDYSDHVQRDLLDALLRAKRSAENNNTAAEFSAEAVGLSDDHLLMTVGDIFGAGVETTTTVLKWAITYLIHYPEVQKQIQEELDRKVGVDRPPQLSDRGSLPFLEATIREVLRIRPVAPLLIPHVALSDTSLGDFTVRKGTRVVINLWSLHHDEKEWTNPDLFNPGRFLSAD 430          

BLAST of CX294560 vs. ExPASy Swiss-Prot
Match: CP17A_HUMAN (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Homo sapiens GN=CYP17A1 PE=1 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 1.422e-23
Identity = 61/163 (37.42%), Postives = 86/163 (52.76%), Query Frame = 1

Query:  103 STECKDILDTLL---------NIIQDKSVEI-ETKHLKHFFADLFIAGNDTTSSTMEWAMAELLHNPXXXXXXXXXXXQTVGKCKPIEESDITRLPYLQAVVKETLRLHPAVPLLLPRKATKDVAIAGFTVPKGAQVFVNVWAIGRDESTWDNPHTFIPERFL 561
            S    ++LDTL+         N   D+  E+    H+     D+F AG +TT+S ++W +A LLHNP           Q VG  +    SD  RL  L+A ++E LRL P  P+L+P KA  D +I  F V KG +V +N+WA+  +E  W  P  F+PERFL
Sbjct:  256 SDSITNMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL 418          

BLAST of CX294560 vs. ExPASy Swiss-Prot
Match: CP21A_PIG (Steroid 21-hydroxylase OS=Sus scrofa GN=CYP21 PE=1 SV=2)

HSP 1 Score: 109.383 bits (272), Expect = 1.857e-23
Identity = 63/188 (33.51%), Postives = 99/188 (52.66%), Query Frame = 1

Query:   37 LEVFDRLVDQRLKHRQEHGCSISTECKDILDTLLNIIQDKSVE-----IETKHLKHFFADLFIAGNDTTSSTMEWAMAELLHNPXXXXXXXXXXXQTVGKCKP---IEESDITRLPYLQAVVKETLRLHPAVPLLLPRKATKDVAIAGFTVPKGAQVFVNVWAIGRDESTWDNPHTFIPERFLGSNAD 576
            +E  D LV+++L+  +E    ++ + +D+LD +L     + VE     +   H+     DLFI G +TT++T+ WA+  LLH+P           + +G       +   D  RLP L A + E LRL P VPL LP +AT+  +I G+ +P+G  V  N+     DE+ W+ PH F P+RFL   A+
Sbjct:  229 IENRDHLVEKQLRRHKES--MVAGQWRDMLDYMLQEAGRQRVEEGQGQLLEGHVHMSVVDLFIGGTETTANTLSWAVVYLLHHPEIQWRLQEELDRELGPGAAGSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRATRPSSIFGYDIPEGTVVIPNLQGAHLDETVWEQPHEFRPDRFLAPGAN 414          

BLAST of CX294560 vs. ExPASy Swiss-Prot
Match: CP17A_RAT (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Rattus norvegicus GN=Cyp17a1 PE=1 SV=2)

HSP 1 Score: 109.383 bits (272), Expect = 1.857e-23
Identity = 58/161 (36.02%), Postives = 87/161 (54.04%), Query Frame = 1

Query:   97 SISTECKDILDTLLNIIQDKSVE------IETKHLKHFFADLFIAGNDTTSSTMEWAMAELLHNPXXXXXXXXXXXQTVGKCKPIEESDITRLPYLQAVVKETLRLHPAVPLLLPRKATKDVAIAGFTVPKGAQVFVNVWAIGRDESTWDNPHTFIPERFL 561
            SIS+    ++   +N   + S E         +H+     D+F AG +TT++ ++W +A L+HNP           Q VG  +    +D + L  L+A ++E LR+ P  P+L+P KA  D +I  FTVPK   V VN+WA+  DE+ WD P  F+PERFL
Sbjct:  257 SISSLTDILIQAKMNSDNNNSCEGRDPDVFSDRHILATVGDIFGAGIETTTTVLKWILAFLVHNPEVKKKIQKEIDQYVGFSRTPTFNDRSHLLMLEATIREVLRIRPVAPMLIPHKANVDSSIGEFTVPKDTHVVVNLWALHHDENEWDQPDQFMPERFL 417          

BLAST of CX294560 vs. ExPASy Swiss-Prot
Match: CP1A1_CANFA (Cytochrome P450 1A1 OS=Canis familiaris GN=CYP1A1 PE=2 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 2.426e-23
Identity = 53/157 (33.76%), Postives = 85/157 (54.14%), Query Frame = 1

Query:  109 ECKDILDTLLNIIQDK------SVEIETKHLKHFFADLFIAGNDTTSSTMEWAMAELLHNPXXXXXXXXXXXQTVGKCKPIEESDITRLPYLQAVVKETLRLHPAVPLLLPRKATKDVAIAGFTVPKGAQVFVNVWAIGRDESTWDNPHTFIPERFL 561
            + +D+ D+L+   QDK      ++++  + + +   DLF AG DT ++ + W++  L+ NP             +G+ +    SD  +LPY++A + ET R    VP  +P   T+D +++GF +PKG  VFVN W I  D+  W NP  F PERFL
Sbjct:  281 QIRDVTDSLIEHCQDKRLDENANIQLSDEKIVNVVLDLFGAGFDTVTTAISWSLLYLVTNPNVQKKIQKELDTVIGRARQPRLSDRPQLPYMEAFILETFRHASFVPFTIPHSTTRDTSLSGFYIPKGRCVFVNQWQINHDQKLWGNPSEFQPERFL 437          

BLAST of CX294560 vs. ExPASy Swiss-Prot
Match: CP1A1_HUMAN (Cytochrome P450 1A1 OS=Homo sapiens GN=CYP1A1 PE=1 SV=1)

HSP 1 Score: 108.227 bits (269), Expect = 4.138e-23
Identity = 54/155 (34.84%), Postives = 84/155 (54.19%), Query Frame = 1

Query:  115 KDILDTLLNIIQDK------SVEIETKHLKHFFADLFIAGNDTTSSTMEWAMAELLHNPXXXXXXXXXXXQTVGKCKPIEESDITRLPYLQAVVKETLRLHPAVPLLLPRKATKDVAIAGFTVPKGAQVFVNVWAIGRDESTWDNPHTFIPERFL 561
            +DI D+L+   Q+K      +V++  + + +   DLF AG DT ++ + W++  L+ NP             +G+ +    SD + LPY++A + ET R    VP  +P   T+D ++ GF +PKG  VFVN W I  D+  W NP  F+PERFL
Sbjct:  279 RDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFL 433          

BLAST of CX294560 vs. ExPASy Swiss-Prot
Match: C77A1_SOLME (Cytochrome P450 77A1 (Fragment) OS=Solanum melongena GN=CYP77A1 PE=2 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 4.884e-23
Identity = 56/192 (29.17%), Postives = 89/192 (46.35%), Query Frame = 1

Query:    4 KRRITVYSAKMLEVFDRLVDQRLKHRQEHGCSISTECKDILDTLLNI-IQDKSVEIETKHLKHFFADLFIAGNDTTSSTMEWAMAELLHNPXXXXXXXXXXXQTVGKCKPIEESDITRLPYLQAVVKETLRLHPAVPLLLPRKATKDVAIAGFTVPKGAQVFVNVWAIGRDESTWDNPHTFIPERFLGSNAD 576
            ++R+     + +E    L+++R    Q  G   +      LDTL ++ ++ +        L    ++    G DTT++ +EW +  L+ NP             VG  K ++E+DI ++PYL AVVKE LR HP     L    T+ V +AG+ +P    V   V  I  D + W +P  F P+RFL    D
Sbjct:  232 RKRVNEVRKRQIETLVPLIEKRRSVVQNPGSDKTAASFSYLDTLFDVKVEGRKSGPTNAELVTLCSEFLNGGTDTTATALEWGIGRLMENPTIQNQLYQEIKTIVGD-KKVDENDIEKMPYLNAVVKELLRKHPPTYFTLTHSVTEPVKLAGYDIPMDTNVEFFVHGISHDPNVWSDPEKFDPDRFLSGRED 422          

HSP 2 Score: 27.7202 bits (60), Expect = 4.884e-23
Identity = 11/23 (47.83%), Postives = 17/23 (73.91%), Query Frame = 3

Query:  615 GRRICPGLPLAIRMLHLMVGSLI 683
            GRRICPGL +A   ++LM+  ++
Sbjct:  439 GRRICPGLGMATVHVNLMLARMV 461