CX294798

BLAST of CX294798 vs. ExPASy Swiss-Prot
Match: CDKL5_HUMAN (Cyclin-dependent kinase-like 5 OS=Homo sapiens GN=CDKL5 PE=1 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 6.655e-18
Identity = 61/169 (36.09%), Postives = 93/169 (55.03%), Query Frame = 1

Query:   28 IIAKYEILECVGSGAYSDVYKGRRLSDNLIVALKEVHDYQ-------SAFREIEALQILQNSPNVVVLHEYFWREDEDAVLVLEFLKTDLATVIAESKKKREGGGDRGISVGEIKRWMVQILCGVDACHRNTIVHRDLKPGNLLIGDDGVLKLADFGQARILL-GNEFN 510
            ++ K+EIL  VG GAY  V K R    + IVA+K+  D +       +  RE++ L+ L+   N+V L E F R  +   LV E+++ ++  ++ E           G+   ++K ++ Q++  +  CH+N IVHRD+KP NLLI  + VLKL DFG AR L  GN  N
Sbjct:    9 VMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQE-NIVELKEAFRRRGK-LYLVFEYVEKNMLELLEEMPN--------GVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNAN 167          

BLAST of CX294798 vs. ExPASy Swiss-Prot
Match: CDK16_RAT (Cell division protein kinase 16 OS=Rattus norvegicus GN=Cdk16 PE=1 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 6.655e-18
Identity = 61/155 (39.35%), Postives = 93/155 (60.00%), Query Frame = 1

Query:   40 YEILECVGSGAYSDVYKGR-RLSDNLIVALKEVH-DYQ-----SAFREIEALQILQNSPNVVVLHEYFWREDEDAVLVLEFLKTDLATVIAESKKKREGGGDRGISVGEIKRWMVQILCGVDACHRNTIVHRDLKPGNLLIGDDGVLKLADFGQA 483
            Y  L+ +G G Y+ VYKG+ +L+DNL VALKE+  +++     +A RE+  L+ L+++ N+V LH+    E +   LV E+L  DL   + +            I++  +K ++ Q+L G+  CHR  ++HRDLKP NLLI + G LKLADFG A
Sbjct:  165 YIKLDKLGEGTYATVYKGKSKLTDNL-VALKEIRLEHEEGAPCTAIREVSLLKDLKHA-NIVTLHDIIHTE-KSLTLVFEYLDKDLKQYLDDCGNV--------INMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLA 308          

BLAST of CX294798 vs. ExPASy Swiss-Prot
Match: CDC2_CAEEL (Cell division control protein 2 homolog OS=Caenorhabditis elegans GN=cdk-1 PE=1 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 6.655e-18
Identity = 58/155 (37.42%), Postives = 85/155 (54.84%), Query Frame = 1

Query:   49 LECVGSGAYSDVYKGRRLSDNLIVALKEVHDYQ-------SAFREIEALQILQNSPNVVVLHEYFWREDEDAVLVLEFLKTDLATVIAESKKKREGGGDRGISVGEIKRWMVQILCGVDACHRNTIVHRDLKPGNLLIGDDGVLKLADFGQARIL 492
            LE +G G Y  VYKG+    N +VA+K++           +A REI  L+ LQ+ PNVV L     +E+    L+ EFL  DL   + +       G D  + +  +K +  QIL  +  CH+  ++HRDLKP NLL+ ++G +KLADFG AR +
Sbjct:   25 LEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQH-PNVVGLEAVIMQENR-LFLIFEFLSFDLKRYMDQL------GKDEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDNNGAIKLADFGLARAI 171          

BLAST of CX294798 vs. ExPASy Swiss-Prot
Match: CDC2A_XENLA (Cell division control protein 2-A OS=Xenopus laevis GN=cdc2-A PE=1 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 6.655e-18
Identity = 59/157 (37.58%), Postives = 83/157 (52.87%), Query Frame = 1

Query:   37 KYEILECVGSGAYSDVYKGRRLSDNLIVALKEVHDYQ-------SAFREIEALQILQNSPNVVVLHEYFWREDEDAVLVLEFLKTDLATVIAESKKKREGGGDRGISVGEIKRWMVQILCGVDACHRNTIVHRDLKPGNLLIGDDGVLKLADFGQAR 486
            +Y  +E +G G Y  VYKGR  +   +VA+K++           +A REI  L+ LQ+ PN+V L +    +D    L+ EFL  DL   +      +       I    +K ++ QIL G+  CH   ++HRDLKP NLLI   GV+KLADFG AR
Sbjct:    3 EYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQH-PNIVCLLDVLM-QDSRLYLIFEFLSMDLKKYLDSIPSGQY------IDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDSKGVIKLADFGLAR 151          

BLAST of CX294798 vs. ExPASy Swiss-Prot
Match: CDK7_RAT (Cell division protein kinase 7 (Fragment) OS=Rattus norvegicus GN=Cdk7 PE=2 SV=2)

HSP 1 Score: 90.1225 bits (222), Expect = 8.691e-18
Identity = 57/158 (36.08%), Postives = 93/158 (58.86%), Query Frame = 1

Query:   43 EILECVGSGAYSDVYKGRRLSDNLIVALKEVH----------DYQSAFREIEALQILQNSPNVVVLHEYFWREDEDAVLVLEFLKTDLATVIAESKKKREGGGDRGISVGEIKRWMVQILCGVDACHRNTIVHRDLKPGNLLIGDDGVLKLADFGQAR 486
            E L+ +G G ++ VYK R  + N IVA+K++             ++A REI+ LQ L + PN++ L + F  +   + LV +F++TDL  +I ++           ++   IK +M+  L G++  H++ I+HRDLKP NLL+ ++GVLKLADFG A+
Sbjct:    5 EKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH-PNIIGLLDAFGHKSNIS-LVFDFMETDLEVIIKDNSLV--------LTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAK 152          

BLAST of CX294798 vs. ExPASy Swiss-Prot
Match: CDK18_MOUSE (Cell division protein kinase 18 OS=Mus musculus GN=Cdk18 PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 8.691e-18
Identity = 63/156 (40.38%), Postives = 96/156 (61.54%), Query Frame = 1

Query:   40 YEILECVGSGAYSDVYKGR-RLSDNLIVALKEVH-DYQ-----SAFREIEALQILQNSPNVVVLHEYFWREDEDAVLVLEFLKTDLATVIAESKKKREGGGDRGISVGEIKRWMVQILCGVDACHRNTIVHRDLKPGNLLIGDDGVLKLADFGQAR 486
            Y  L+ +G G Y+ V+KGR +L++NL VALKE+  +++     +A RE+  L+ L+++ N+V LH+     D    LV E+L +DL       K+  +  G+  +++  +K +M Q+L G+  CH   I+HRDLKP NLLI + G LKLADFG AR
Sbjct:  121 YVKLDKLGEGTYATVFKGRSKLTENL-VALKEIRLEHEEGAPCTAIREVSLLKDLKHA-NIVTLHDLI-HTDRSLTLVFEYLDSDL-------KQYLDHCGNL-MNMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLAR 265          

BLAST of CX294798 vs. ExPASy Swiss-Prot
Match: CDC2_ORYLU (Cell division control protein 2 homolog OS=Oryzias luzonensis GN=cdc2 PE=2 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 8.691e-18
Identity = 60/156 (38.46%), Postives = 84/156 (53.85%), Query Frame = 1

Query:   40 YEILECVGSGAYSDVYKGRRLSDNLIVALKEVHDYQ-------SAFREIEALQILQNSPNVVVLHEYFWREDEDAVLVLEFLKTDLATVIAESKKKREGGGDRGISVGEIKRWMVQILCGVDACHRNTIVHRDLKPGNLLIGDDGVLKLADFGQAR 486
            Y  +E +G G Y  VYKGR  S   +VA+K++           +A RE+  LQ L++ PNVV L +   +E     L+ EFL  DL   +      +       +    +K ++ QIL G+  CHR  ++HRDLKP NLLI + GV+KLADFG AR
Sbjct:    4 YVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH-PNVVRLLDVLMQESR-LYLIFEFLSMDLKKYLDSIPSGQY------MDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKGVIKLADFGLAR 151          

BLAST of CX294798 vs. ExPASy Swiss-Prot
Match: CDC2_ORYLA (Cell division control protein 2 homolog OS=Oryzias latipes GN=cdc2 PE=2 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 8.691e-18
Identity = 60/156 (38.46%), Postives = 84/156 (53.85%), Query Frame = 1

Query:   40 YEILECVGSGAYSDVYKGRRLSDNLIVALKEVHDYQ-------SAFREIEALQILQNSPNVVVLHEYFWREDEDAVLVLEFLKTDLATVIAESKKKREGGGDRGISVGEIKRWMVQILCGVDACHRNTIVHRDLKPGNLLIGDDGVLKLADFGQAR 486
            Y  +E +G G Y  VYKGR  S   +VA+K++           +A RE+  LQ L++ PNVV L +   +E     L+ EFL  DL   +      +       +    +K ++ QIL G+  CHR  ++HRDLKP NLLI + GV+KLADFG AR
Sbjct:    4 YVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH-PNVVRLLDVLMQESR-LYLIFEFLSMDLKKYLDSIPSGQY------MDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKGVIKLADFGLAR 151          

BLAST of CX294798 vs. ExPASy Swiss-Prot
Match: CDC2_ORYJA (Cell division control protein 2 homolog OS=Oryzias javanicus GN=cdc2 PE=2 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 8.691e-18
Identity = 60/156 (38.46%), Postives = 84/156 (53.85%), Query Frame = 1

Query:   40 YEILECVGSGAYSDVYKGRRLSDNLIVALKEVHDYQ-------SAFREIEALQILQNSPNVVVLHEYFWREDEDAVLVLEFLKTDLATVIAESKKKREGGGDRGISVGEIKRWMVQILCGVDACHRNTIVHRDLKPGNLLIGDDGVLKLADFGQAR 486
            Y  +E +G G Y  VYKGR  S   +VA+K++           +A RE+  LQ L++ PNVV L +   +E     L+ EFL  DL   +      +       +    +K ++ QIL G+  CHR  ++HRDLKP NLLI + GV+KLADFG AR
Sbjct:    4 YVKIEKIGEGTYGVVYKGRHKSTGQVVAMKKIRLESEEEGVPSTAVREVSLLQELKH-PNVVRLLDVLMQESR-LYLIFEFLSMDLKKYLDSIPSGQY------MDPMLVKSYLYQILEGIYFCHRRRVLHRDLKPQNLLIDNKGVIKLADFGLAR 151          

BLAST of CX294798 vs. ExPASy Swiss-Prot
Match: CDK7_XENLA (Cell division protein kinase 7 OS=Xenopus laevis GN=cdk7 PE=1 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 1.135e-17
Identity = 59/160 (36.88%), Postives = 94/160 (58.75%), Query Frame = 1

Query:   37 KYEILECVGSGAYSDVYKGRRLSDNLIVALK--------EVHD--YQSAFREIEALQILQNSPNVVVLHEYFWREDEDAVLVLEFLKTDLATVIAESKKKREGGGDRGISVGEIKRWMVQILCGVDACHRNTIVHRDLKPGNLLIGDDGVLKLADFGQAR 486
            +YE L+ +G G ++ VYK R  + + IVA+K        E +D   ++A REI+ LQ L + PN++ L + F  +   + LV +F++TDL  +I ++           ++   IK +M+  L G++  H   I+HRDLKP NLL+ ++GVLKLADFG A+
Sbjct:   17 QYEKLDFLGEGQFATVYKARDKNTDRIVAIKKIKLGHRAEANDGINRTALREIKLLQELSH-PNIIGLLDAFGHKSNIS-LVFDFMETDLEVIIKDTSLV--------LTPAHIKSYMLMTLQGLEYLHHLWILHRDLKPNNLLLDENGVLKLADFGLAK 166