CX295720

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: ABL2_MOUSE (Tyrosine-protein kinase ABL2 OS=Mus musculus GN=Abl2 PE=1 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 5.484e-12
Identity = 34/109 (31.19%), Postives = 56/109 (51.38%), Query Frame = 2

Query:   44 KMDMQASKEFRAELKVLTHVHHLNLVRLIGYC-FEGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNFRAKI 367
            K D    +EF  E  V+  + H NLV+L+G C  E    +V E++  GNL  +LR   R+ +     L +A   +  +EY+ +     +IHRD+ + N L+ +N   K+
Sbjct:  320 KEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKN---FIHRDLAARNCLVGENHVVKV 425          

HSP 2 Score: 32.3426 bits (72), Expect = 5.484e-12
Identity = 20/53 (37.74%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAVSGNV-SPKTDVFAFGVVLYEL 519
            DFGL++L   G+     +G +    +  PE+++ N  S K+DV+AFGV+L+E+
Sbjct:  427 DFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEI 478          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: ABL2_HUMAN (Tyrosine-protein kinase ABL2 OS=Homo sapiens GN=ABL2 PE=1 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 5.484e-12
Identity = 34/109 (31.19%), Postives = 56/109 (51.38%), Query Frame = 2

Query:   44 KMDMQASKEFRAELKVLTHVHHLNLVRLIGYC-FEGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNFRAKI 367
            K D    +EF  E  V+  + H NLV+L+G C  E    +V E++  GNL  +LR   R+ +     L +A   +  +EY+ +     +IHRD+ + N L+ +N   K+
Sbjct:  320 KEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKN---FIHRDLAARNCLVGENHVVKV 425          

HSP 2 Score: 32.3426 bits (72), Expect = 5.484e-12
Identity = 20/53 (37.74%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAVSGNV-SPKTDVFAFGVVLYEL 519
            DFGL++L   G+     +G +    +  PE+++ N  S K+DV+AFGV+L+E+
Sbjct:  427 DFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEI 478          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: Y1634_ARATH (Probable LRR receptor-like serine/threonine-protein kinase At1g63430 OS=Arabidopsis thaliana GN=At1g63430 PE=1 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 5.566e-12
Identity = 36/121 (29.75%), Postives = 64/121 (52.89%), Query Frame = 2

Query:   20 AIQKAAIKKMDMQASKE--FRAELKVLTHVHHLNLVRLIGYCFEGS---LCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNFRAKI 367
            A+    +K+ D     E  F+ E+  L  ++H N  +L+GYC E S     +V+E+  NG L +HL       ++W+ R++I +  ARGL+Y+H    P +   ++ S  I + ++F  K+
Sbjct:  386 AVISLCVKEEDWTGYLELYFQREVADLARLNHENTAKLLGYCKEISPFTRMLVFEYASNGTLYEHLHYGEAALVSWARRMKIVIGIARGLKYLHMELDPPFTISELSSNAIYLTEDFTPKL 506          

HSP 2 Score: 28.1054 bits (61), Expect = 5.566e-12
Identity = 29/121 (23.97%), Postives = 55/121 (45.45%), Query Frame = 1

Query:  352 LPRKDFGLTKLTEFGNASFYTSGLQGTFGYFPPEAVSGNVSPKTDVFAFGVVLYELISAKQAIVTTNETITQSKG-LVALFEEVLRQPAPRENLHKLVDPRLGDNYPLDSVIKMAQLARAC 711
            L R +  L  ++  G+     +G++  +       VSGN+      +AFG++L E++S +           + KG L+   +E L  P   E +  LVDP L  ++  + +  + ++A  C
Sbjct:  516 LARSEKNLRNISSQGSICVLPNGMESRY-----LDVSGNI------YAFGILLLEIVSGR-------PPYCKDKGFLIEWAKEFLEAP---EAMSGLVDPEL-KHFNQEDLETVCEVASQC 614          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: ROC11_DICDI (Probable serine/threonine-protein kinase roco11 OS=Dictyostelium discoideum GN=roco11 PE=3 SV=1)

HSP 1 Score: 59.3066 bits (142), Expect = 7.078e-12
Identity = 30/93 (32.26%), Postives = 57/93 (61.29%), Query Frame = 2

Query:   65 KEFRAELKVLTHVHHLNLVRLIGYCFEGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILI 343
            +EF  E+ +++ ++HLN+V+L G   +    +V EF  +G+L   L    +  + WS ++++ LD A+G+EY+     P+ +HRD++S NI +
Sbjct: 1233 QEFHHEMYIMSSLNHLNIVKLFG-SMQNPPRMVMEFAPHGDLYHFLEK--KKNIKWSFKVRLMLDIAKGIEYLQNQNPPI-VHRDLRSPNIFL 1321          

HSP 2 Score: 31.5722 bits (70), Expect = 7.078e-12
Identity = 16/58 (27.59%), Postives = 31/58 (53.45%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAVSGNVS--PKTDVFAFGVVLYELISAK 531
            DFGL++      + +  SGL G F +  PE +    S   K D ++F ++L+ +++ +
Sbjct: 1336 DFGLSQ-----QSLYSVSGLLGNFQWMAPETIGAEESYTEKIDTYSFSMILFTILTGE 1388          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: ABL1_MOUSE (Proto-oncogene tyrosine-protein kinase ABL1 OS=Mus musculus GN=Abl1 PE=1 SV=3)

HSP 1 Score: 58.9214 bits (141), Expect = 7.128e-12
Identity = 34/109 (31.19%), Postives = 56/109 (51.38%), Query Frame = 2

Query:   44 KMDMQASKEFRAELKVLTHVHHLNLVRLIGYCF-EGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNFRAKI 367
            K D    +EF  E  V+  + H NLV+L+G C  E    ++ EF+  GNL  +LR   R  ++    L +A   +  +EY+ +     +IHRD+ + N L+ +N   K+
Sbjct:  274 KEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKN---FIHRDLAARNCLVGENHLVKV 379          

HSP 2 Score: 31.9574 bits (71), Expect = 7.128e-12
Identity = 20/53 (37.74%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAVSGN-VSPKTDVFAFGVVLYEL 519
            DFGL++L   G+     +G +    +  PE+++ N  S K+DV+AFGV+L+E+
Sbjct:  381 DFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEI 432          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: ABL_MLVAB (Tyrosine-protein kinase transforming protein Abl OS=Abelson murine leukemia virus GN=ABL PE=1 SV=1)

HSP 1 Score: 58.9214 bits (141), Expect = 7.204e-12
Identity = 34/109 (31.19%), Postives = 56/109 (51.38%), Query Frame = 2

Query:   44 KMDMQASKEFRAELKVLTHVHHLNLVRLIGYCF-EGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNFRAKI 367
            K D    +EF  E  V+  + H NLV+L+G C  E    ++ EF+  GNL  +LR   R  ++    L +A   +  +EY+ +     +IHRD+ + N L+ +N   K+
Sbjct:  160 KEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKN---FIHRDLAARNCLVGENHLVKV 265          

HSP 2 Score: 31.9574 bits (71), Expect = 7.204e-12
Identity = 20/53 (37.74%), Postives = 34/53 (64.15%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAVSGN-VSPKTDVFAFGVVLYEL 519
            DFGL++L   G+     +G +    +  PE+++ N  S K+DV+AFGV+L+E+
Sbjct:  267 DFGLSRLMT-GDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEI 318          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: IRAK2_HUMAN (Interleukin-1 receptor-associated kinase-like 2 OS=Homo sapiens GN=IRAK2 PE=1 SV=2)

HSP 1 Score: 65.855 bits (159), Expect = 7.239e-12
Identity = 37/124 (29.84%), Postives = 62/124 (50.00%), Query Frame = 2

Query:   71 FRAELKVLTHVHHLNLVRLIGYCFEGSL-CVVYEFIENGNLSQHLRGSG-RDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNFRAKIXXXXXXXXXEMLHSTLVVFKVHL 436
            F+AEL++     H N++ ++G+C        +Y ++ NG+L   L+G G  DPL W  R+ I       +EY+H   +   IH ++KS+N+L+D+N   K+             S   + K HL
Sbjct:  254 FQAELQICLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRLQGQGGSDPLPWPQRVSICSGLLCAVEYLHGLEI---IHSNVKSSNVLLDQNLTPKLAHPMAHLCPVNKRSKYTMMKTHL 374          

HSP 2 Score: 25.0238 bits (53), Expect = 7.239e-12
Identity = 11/41 (26.83%), Postives = 25/41 (60.98%), Query Frame = 1

Query:  421 LQGTFGYFPPEAVS-GNVSPKTDVFAFGVVLYELISAKQAI 540
            L+ +  Y P + +  G ++ + D+F+ G+VL E+++   A+
Sbjct:  375 LRTSAAYLPEDFIRVGQLTKRVDIFSCGIVLAEVLTGIPAM 415          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: BRAF1_COTJA (B-Raf proto-oncogene serine/threonine-protein kinase OS=Coturnix coturnix japonica GN=BRAF PE=2 SV=1)

HSP 1 Score: 54.6842 bits (130), Expect = 9.332e-12
Identity = 31/104 (29.81%), Postives = 55/104 (52.88%), Query Frame = 2

Query:   56 QASKEFRAELKVLTHVHHLNLVRLIGYCFEGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNFRAKI 367
            Q  + F+ E+ VL    H+N++  +GY  +  L +V ++ E  +L  HL             + IA  +A+G++Y+H  ++   IHRD+KS NI + ++   KI
Sbjct:  533 QQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLH-IIETKFEMIKLIDIARQTAQGMDYLHAKSI---IHRDLKSNNIFLHEDLTVKI 632          

HSP 2 Score: 35.8094 bits (81), Expect = 9.332e-12
Identity = 20/60 (33.33%), Postives = 32/60 (53.33%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAV----SGNVSPKTDVFAFGVVLYELISAK 531
            DFGL  +    + S     L G+  +  PE +        S ++DV+AFG+VLYEL++ +
Sbjct:  634 DFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQ 693          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: BRAF1_CHICK (B-Raf proto-oncogene serine/threonine-protein kinase OS=Gallus gallus GN=BRAF PE=1 SV=1)

HSP 1 Score: 54.6842 bits (130), Expect = 9.332e-12
Identity = 31/104 (29.81%), Postives = 55/104 (52.88%), Query Frame = 2

Query:   56 QASKEFRAELKVLTHVHHLNLVRLIGYCFEGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNFRAKI 367
            Q  + F+ E+ VL    H+N++  +GY  +  L +V ++ E  +L  HL             + IA  +A+G++Y+H  ++   IHRD+KS NI + ++   KI
Sbjct:  533 QQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLH-IIETKFEMIKLIDIARQTAQGMDYLHAKSI---IHRDLKSNNIFLHEDLTVKI 632          

HSP 2 Score: 35.8094 bits (81), Expect = 9.332e-12
Identity = 20/60 (33.33%), Postives = 32/60 (53.33%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAV----SGNVSPKTDVFAFGVVLYELISAK 531
            DFGL  +    + S     L G+  +  PE +        S ++DV+AFG+VLYEL++ +
Sbjct:  634 DFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQ 693          

BLAST of CX295720 vs. ExPASy Swiss-Prot
Match: BRAF1_MOUSE (B-Raf proto-oncogene serine/threonine-protein kinase OS=Mus musculus GN=Braf PE=1 SV=2)

HSP 1 Score: 54.6842 bits (130), Expect = 9.333e-12
Identity = 31/104 (29.81%), Postives = 55/104 (52.88%), Query Frame = 2

Query:   56 QASKEFRAELKVLTHVHHLNLVRLIGYCFEGSLCVVYEFIENGNLSQHLRGSGRDPLAWSTRLQIALDSARGLEYIHEHTVPVYIHRDIKSANILIDKNFRAKI 367
            Q  + F+ E+ VL    H+N++  +GY  +  L +V ++ E  +L  HL             + IA  +A+G++Y+H  ++   IHRD+KS NI + ++   KI
Sbjct:  530 QQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLH-IIETKFEMIKLIDIARQTAQGMDYLHAKSI---IHRDLKSNNIFLHEDLTVKI 629          

HSP 2 Score: 35.8094 bits (81), Expect = 9.333e-12
Identity = 20/60 (33.33%), Postives = 32/60 (53.33%), Query Frame = 1

Query:  364 DFGLTKLTEFGNASFYTSGLQGTFGYFPPEAV----SGNVSPKTDVFAFGVVLYELISAK 531
            DFGL  +    + S     L G+  +  PE +        S ++DV+AFG+VLYEL++ +
Sbjct:  631 DFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQ 690